GPR(Ground Penetrating Radar) was used for imaging the interior of the historical masonry such as stone pagoda in order to provide the basic information of safely inspection. The scope of the imaging was restricted to the foundation part of stone pagoda that transferred the load of the pagoda to the ground. Kirchhoff migration and traveltime tomography was used for imaging the outer stone and the inside of stone pagoda, respectively. From the migrated images, we could measure the thickness and the shape of the boundaries of the outer stone in the foundation part. From the reconstructed tomograms for the physical model, we could get the GPR propagation velocity distribution and exactly find the position of the air in the model and calculate the average velocity with respect to the different filling materials. The properties and the shape of the interior materials of stone pagoda can be basic informations for the safety inspection.
In order to improve polymer electrolyte membrane fuel cell (PEMFC) durability, the durability of membrane electrode assemblies (MEA), in which the electrochemical reactions actually occur, is one of the vital issues. Many articles have dealt with catalyst layer degradation of the durability-related factors on MEAs in relation to loss of catalyst surface area caused by agglomeration, dissolution, migration, formation of metal complexes and oxides, and/or instability of the carbon support. Degradation of catalyst layer during long-term operation includes cracking or delamination of the layer which result either from change in the catalyst microstructure or loss of electronic or ionic contact with the active surface, can result in apparent activity loss in the catalyst layer. Membrane degradation of the durability-related factors on MEAs can be caused by mechanical or thermal stress resulting in formation of pinholes and tears and/or by chemical attack of hydrogen peroxide radicals formed during the electrochemical reactions. All of these effects, the mechanical damage of membrane and degradation of catalyst layers are more facilitated by uneven stress or improper MEA fabrication process. In order to improve the PEMFC durability, therefore, it is most important to minimize the uneven stress or improper MEA fabrication process in the course of the fabrication of MEA. We analyzed the effects of the MEA fabrication condition on the PEMFC durability with MEA produced using CCM (catalyst coated membrane) method. This paper also investigated the effects of MEA fabrication condition on the PEMFC durability by adding additional treatment process, hot pressing and pressing, on the MEA produced using CCM method.
Cloud computing is becoming an effective and efficient way of computing resources and computing service integration. Through centralized management of resources and services, cloud computing delivers hosted services over the internet, such that access to shared hardware, software, applications, information, and all resources is elastically provided to the consumer on-demand. The main enabling technology for cloud computing is virtualization. Virtualization software creates a temporarily simulated or extended version of computing and network resources. The objectives of virtualization are as follows: first, to fully utilize the shared resources by applying partitioning and time-sharing; second, to centralize resource management; third, to enhance cloud data center agility and provide the required scalability and elasticity for on-demand capabilities; fourth, to improve testing and running software diagnostics on different operating platforms; and fifth, to improve the portability of applications and workload migration capabilities. One of the key features of cloud computing is elasticity. It enables users to create and remove virtual computing resources dynamically according to the changing demand, but it is not easy to make a decision regarding the right amount of resources. Indeed, proper provisioning of the resources to applications is an important issue in IaaS cloud computing. Most web applications encounter large and fluctuating task requests. In predictable situations, the resources can be provisioned in advance through capacity planning techniques. But in case of unplanned and spike requests, it would be desirable to automatically scale the resources, called auto-scaling, which adjusts the resources allocated to applications based on its need at any given time. This would free the user from the burden of deciding how many resources are necessary each time. In this work, we propose an analytical and efficient VM-level scaling scheme by modeling each VM in a data center as an M/M/1 processor sharing queue. Our proposed VM-level scaling scheme is validated via a numerical experiment.
Heo, Dae Nyoung;Lee, Jun Young;Jeong, Naeyang;Ku, Bon Chul;Song, Choonghan
Journal of Korea Technology Innovation Society
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v.17
no.1
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pp.264-288
/
2014
The competition for attracting outstanding HRST (human resource for science and technology) who can lead technological innovation is heating up all over the world. The various concepts, which are brain drain, brain gain, brain overflow, brain migration, brain circulation, are used to explain the international mobility of HRST. But the concept of brain scout is the more adequate for explaining in the case of outstanding HRST as the main cause of excessive competition for scouting. This study analyzed the critical factors of the determinants of Korean students in the USA who have intentions of returning to Korea in view of brain scout. As the first step in this study, potential factors and hypothesis are established by the interviews. As the second step, the major factors are examined by surveys and hypothesis testing. Also, a new model for decision-making is proposed which describes intentions of returning to Korea by logistic regression analysis and contributions of each factor derived from this study were compared. Finally, policy implications for attracting outstanding HRST and the limit of this study are discussed.
Proceedings of the Korea Concrete Institute Conference
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2008.04a
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pp.525-528
/
2008
For well-constructed concrete, its service life is a long term and it has an enough durability performance. However, for cracked concrete, it is clear that cracks should be preferential channel for the penetration of aggressive substance such as chloride ions according to author's previous researches. In order to enhance the lifetime of cracked concrete, critical issues in the performance of the concrete is the risk of chloride-induced corrosion. Even though crack width can be reduced due to the high reinforcement ratio, the question is to which extend these cracks may jeopardize the durability of cracked concrete. If the size of crack is small, surface treatment system can be considered as one of the best options to extend the service life of concrete structures exposed to marine environment simply in terms of cost effectiveness versus durability performance. Thus, it should be decided to undertake an experimental study on the effect of different types of surface treatment system, which are expected to seal the concrete and the cracks to chloride-induced corrosion in particular. In this study, it is examined the effect of surfaced treated systems on chloride penetration through microcracks. Single surface treatments of penetrant or coating and double application were considered as an experimental variation. RCM (Rapid Chloride Migration) testing is accomplished to visualize chloride penetration via cracks.
The gas permeability behavior of unsaturated bentonite-based materials is of major importance for ensuring effective sealing of high-level radwaste repositories. This study investigated this by taking a sample of Granular Bentonite Material (GBM) at the end of the Engineered Barrier Emplacement (EB) experiment in the Opalinus Clay, placing it under different humidity conditions until it achieved equilibration, and testing the change in the gas permeability under loading and unloading. Environmental humidity is shown to have a significant effect on the water content, saturation, porosity and dry density of GBM and to affect its gas permeability. Higher sensitivity to confining pressure is exhibited by samples equilibrated at higher relative humidity (RH). It should be noted that for the sample at RH=98%, when the confining pressure is raised from 1 MPa to 6 MPa, gas permeability can be reduced from 10-16 m2 to 10-19 m2, which is close to the requirements of gas tightness. Due to higher water content and easier compressibility, samples equilibrated under higher RH show greater irreversibility during the loading and unloading process. The effective gas permeability of highly saturated samples can be increased by 2-3 orders of magnitude after 105℃ drying. In addition, cracks possibly occurred during the dehydration and drying process will become the main channel for gas migration, which will greatly affect the sealing performance of GBM.
Caval syndrome is a severe complication of canine heartworm disease in which affected dogs present with various clinical signs that are often life-threatening. In cases of severe infection, adulticidal treatment has numerous complications as a result of a marked immune response against dead worms. Therefore, several surgical and non-surgical methods, including interventional extraction, have been applied in veterinary medicine. Despite the usefulness and efficiency of conventional retrieval devices, a few associated limitations must be addressed to reduce their risks and increase their applicability. Herein, we introduced a case of treating three dogs with caval syndrome by applying a newly developed heartworm basket device. The dogs were diagnosed with heartworm disease by heartworm antigen testing and direct smear. Imaging findings revealed remarkable remodeling of the right heart and pulmonary vessels and the presence of heartworms in the right heart. Additionally, heartworms were confirmed in the distal part of the abdominal aorta and femoral arteries in one dog, indicating aberrant systemic migration of the worms. Under general anesthesia, the heartworm basket device was introduced into the right heart via femoral venotomy and arteriotomy in one dog and jugular venotomy in the other two dogs. Although the number of cases in this study was small, the basket device was successful in gradual and cautious extraction of the heartworms in all three dogs. They exhibited good prognosis of clinical symptoms as indicated by imaging analyses.
Aram Kang;Minjoo Yeom;Hyekwon Kim;Sun-Woo Yoon;Dae-Gwin Jeong;Hyong-Joon Moon;Kwang-Soo Lyoo;Woonsung Na;Daesub Song
IMMUNE NETWORK
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v.21
no.1
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pp.11.1-11.10
/
2021
Coronavirus causes an infectious disease in various species and crosses the species barriers leading to the outbreak of zoonotic diseases. Due to the respiratory diseases are mainly caused in humans and viruses are replicated and excreted through the respiratory tract, the nasal fluid and sputum are mainly used for diagnosis. Early diagnosis of coronavirus plays an important role in preventing its spread and is essential for quarantine policies. For rapid decision and prompt triage of infected host, the immunochromatographic assay (ICA) has been widely used for point of care testing. However, when the ICA is applied to an expectorated sputum in which antigens are present, the viscosity of sputum interferes with the migration of the antigens on the test strip. To overcome this limitation, it is necessary to use a mucolytic agent without affecting the antigens. In this study, we combined known mucolytic agents to lower the viscosity of sputum and applied that to alpha and beta coronavirus, porcine epidemic diarrhea virus (PEDV) and Middle East respiratory syndrome coronavirus (MERS-CoV), respectively, spiked in sputum to find optimal pretreatment conditions. The pretreatment method using tris(2-carboxyethyl)phosphine (TCEP) and BSA was suitable for ICA diagnosis of sputum samples spiked with PEDV and MERS-CoV. This sensitive assay for the detection of coronavirus in sputum provides an useful information for the diagnosis of pathogen in low respiratory tract.
Proplast and Porous Polyethylene which have porous structures as low-modulus polymers have been recently used in maxillofacial plastic and reconstructive surgery. The purpose of this study was to compare the response of adajacent tissue, new bone formation and stability after augmentation by differen methods of subperiosteal graft using proplast and purous polythylene in rabbit mandible. The augmentation procedure was carried out by dividing into two groups, A and B. A group consisted of subperiosteal graft on the cortex, and the other B group was made up only graft following artificial decortication in the mandibular body of rabbit. The experimental animals were sacrificed on the 1st, 2nd, 4th and 8th week after grafting for macroscopic and light microscopic examination. The samples extracted at the 6th postgrafting week were also used for biometric testing and scanning electron microscopic examination. The results obtained from this study were as follows : 1. Macroscopically, infection of graft site, deformation and migration of graft material were not observed in all experimental groups. 2. B group showed more rapid and increased bone formation and the greater stability than A group, and tissue response was similar to each other. 3. In the tissue response, macrophages and cellular infiltrations were observed in Proplast group, but few in PHDPE group. 4. In bone formation of A group, Proplast group showed no bone formation until the 8th week, but PHDPE group showed small quantity of osteoid tissue from the 2nd week and appositional bone growth with new bone formation at the 8th week. 5. In bone formation of B group, both Proplast and PHDPE group showed bone formation, but PHDPE group showed more rapid and larger bone formation. 6. In pattern of bone formation, Proplast group mainly showed appositional bone growth pattern connected with graft site. On the other hand, PHDPE group showed mixed pattern of new bone formation in the pore connective tissue with appositional bone growth from graff site. 7. The maximum mean values of shear stress were serially $111.3gf/mm^{2}$ in PHDPE of B group, $84.8gf/mm^{2}$ in PHDPE of A group, $32.9gf/mm^{2}$ in Proplast B group, and $15.7gf/mm^{2}$ in Proplast of A group. From above results, It was suggested that the capacity of bone formation and stability between bone and graft material were dependent on the pore size and structure of graft material itself, the state of graft site and tissue response.
Purpose: The aim of this study was to present new a model that allows the study of the bone healing process, with an emphasis on the biological behavior of different graft-to-host interfaces. A standardized "over-inlay" surgical technique combined with a differential histomorphometric analysis is presented in order to optimize the use of critical-size calvarial defects in pre-clinical testing. Methods: Critical-size defects were created into the parietal bone of 8 male Wistar rats. Deproteinized bovine bone (DBBM) blocks were inserted into the defects, so that part of the block was included within the calvarial thickness and part exceeded the calvarial height (an "over-inlay" graft). All animals were sacrificed at 1 or 3 months. Histomorphometric and immunohistochemical evaluation was carried out within distinct regions of interest (ROIs): the areas adjacent to the native bone (BA), the periosteal area (PA) and the central area (CA). Results: The animals healed without complications. Differential morphometry allowed the examination of the tissue composition within distinct regions: the BA presented consistent amounts of new bone formation (NB), which increased over time ($24.53%{\pm}1.26%$ at 1 month; $37.73%{\pm}0.39%$ at 3 months), thus suggesting that this area makes a substantial contribution toward NB. The PA was mainly composed of fibrous tissue ($71.16%{\pm}8.06%$ and $78.30%{\pm}2.67%$, respectively), while the CA showed high amounts of DBBM at both time points ($78.30%{\pm}2.67%$ and $74.68%{\pm}1.07%$, respectively), demonstrating a slow remodeling process. Blood vessels revealed a progressive migration from the interface with native bone toward the central area of the graft. Osterix-positive cells observed at 1 month within the PA suggested that the periosteum was a source of osteoprogenitor elements. Alkaline phosphatase data on matrix deposition confirmed this observation. Conclusions: The present model allowed for a standardized investigation of distinct graft-to-host interfaces both at vertically augmented and inlay-augmented sites, thus possibly limiting the number of animals required for pre-clinical investigations.
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