• 한국수학교육학회지시리즈E:수학교육논문집
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• 제35권4호
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• pp.359-376
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• 2021

본 연구는 수학 학습에서 긍정적이거나 부정적으로 발현되는 학습자의 감정이나 학습자가 보유한 수학에 대한 신념, 태도가 수학 학습 결과에 영향을 미친다는 연구에 기반하여 학습자 감정이나 정의적 요소들을 학습자 자신의 학습 목표나 목적에 맞게 조절할 수 있는 요소를 강구하고자 하였다. 이를 위하여 메타 정의에 관련된 연구들을 연결망 분석을 통하여 종합적으로 분석함으로써 메타 정의의 정의적 요소를 추출하고 이에 대한 개념을 분류, 그 의미를 탐색하였다. 그 결과 메타 정의의 정의적 요소로서 감정, 태도, 신념, 메타 정의의 개념 요소는 알아차리기(자각), 평가, 조절, 활용, 모니터링으로 도출할 수 있으며, 각 개념 요소에 대한 의미를 정의하였다. 본 연구 결과는 수학교육 분야에서 의미 있게 다뤄지는 정의적 영역과 관련하여 정의적 요소의 규명이나 특성에 대한 고찰을 넘어, 수학 학습에서 감정적 영역을 조절하고 이를 활용하기 위한 방안으로의 메타 정의의 개념 요소와 의미를 탐색하였다는데 그 의의가 있다.

• Journal of Acupuncture Research
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• 제38권2호
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• pp.110-121
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• 2021

The objective of this study was to conduct a systematic review and network meta-analysis to evaluate and compare the effectiveness of various types of acupuncture for menopausal hot flashes (HF). Randomized controlled trials (RCTs) were retrieved from 8 electronic databases, and the risk of bias was evaluated for the included studies. Pairwise meta-analysis and network meta-analysis were performed using Review Manager and R software for indirect comparison and ranking, respectively. In total, 23 RCTs (2,302 patients) were eligible for systematic review, of which 10 were included in network meta-analysis. Network meta-analysis showed manual acupuncture (MA) had the highest probability of reducing HF frequency and severity, followed by sham acupuncture (SA), electroacupuncture, usual care, or no treatment; furthermore, warm acupuncture significantly improved menopause-specific quality of life compared with MA or electroacupuncture. Compared with hormone replacement therapy, acupuncture had less efficacy in reducing HF frequency but enhanced menopause-specific quality of life. There was no significant difference between MA and SA in mitigating HF. The existing evidence showed that MA could be used for alleviating menopausal HF. However, it is recommended that more high-quality RCTs should be performed.

• Nutrition Research and Practice
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• 제17권1호
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• pp.62-72
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• 2023

BACKGROUND/OBJECTIVES: Many studies have revealed an association between fat mass and the obesity-related gene (FTO) and obesity. On the other hand, no meta-analysis was conducted with data from only Koreans. Therefore, this study performed a meta-analysis using Korean data to provide evidence for the association between FTO single nucleotide polymorphisms (SNPs) and the risk of obesity among Korean adults. SUBJECT/METHODS: Meta-analysis was finally conducted with data extracted from seven datasets of four studies performed on Korean adults after the screening passed. Five kinds of FTO SNPs (rs9939609, rs7193144, rs9940128, rs8050136, and rs9926289) were included, and the relationship between FTO SNPs and body mass index (BMI) was investigated using linear regression with an additive model adjusted for covariants, such as age, sex, and area. RESULTS: The minor alleles of FTO SNPs were associated with increased BMI (odds ratio [OR], 1.31; 95% confidence interval [CI], 1.21-1.42). In sub-group analysis, FTO rs9939609 T>A was significantly associated with BMI (OR, 1.23; 95% CI, 1.06-1.42). The other FTO SNPs together were significantly associated with BMI (OR, 1.37; 95% CI, 1.25-1.49). The publication bias was not observed based on Egger's test. CONCLUSIONS: This meta-analysis showed that minor alleles in the FTO SNPs were significantly associated with an increased BMI among Korean adults. This meta-analysis is the first to demonstrate that minor alleles in the FTO SNPs contribute significantly to the increased risk of obesity among Korean adults using data from a Korean population.

• 자원ㆍ환경경제연구
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• 제16권1호
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• pp.65-98
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• 2007

본 연구의 목적은 국내에서 수행된 습지가치추정 선행연구를 대상으로 메타회귀분석을 실시하여, 습지가치에 영향을 미치는 인자들을 규명하고 정책적 시사점을 도출하며, 국내 자연환경 가치추정 분야에 메타회귀분석의 적용 가능성을 검토하는 데 있다. 메타회귀분석은 기존에 축적되어 있는 연구로부터의 정보를 희귀분석을 사용하여 종합하는 기법으로써, 선행연구에서 관찰되는 가치추정치를 종속변수로 연구의 특성, 예를 들면, 대상지의 특성, 추정기법, 모집단의 인구 사회학적 특성 등을 설명변수로 설정하여 분석한다. 이야기체 문헌검토와 비교할 때 메타회귀분석의 가장 큰 장점은 연구자의 자의적 판단을 피하고 통계적 신뢰성에 기반을 둔 객관적인 결론을 도출할 수 있다는 점이다. 실증분석 결과 우리나라의 경우 단위면적당 습지가치는 어떤 습지기능을 대상으로 하였는지보다는 어떤 가치추정기법을 사용했는지에 따라 더 큰 영향을 받는 것으로 나타났다. 또한 습지면적과 습지가치는 유의한 음의 상관관계를 보임으로써 생태학적 원칙보다는 경제학적 원칙이 적용되고 있음을 확인할 수 있었으며, 이러한 점은 습지보호 및 관리정책에 시사하는 바가 크다. 본 연구의 사례분석을 통해 메타회귀분석은 선행연구 결과를 종합하고 관련정책 수립시 유용한 정보를 제공할 수 있는 분석의 틀로써 충분한 활용 가능성을 갖고 있는 것으로 판단된다. 그러나 본 연구는 메타분석의 활용 가능성뿐만 아니라 한계 및 불확실성의 존재를 확인하는 계기도 되었다. 메타회귀분석의 유효성과 신뢰성을 높이기 위해서는 지속적인 관련연구의 DB 구축, 개별연구의 질 향상을 위한 노력, 추정모델의 개선을 위한 연구 등이 병행해서 이루어져야 할 것으로 생각된다.

• Asian Pacific Journal of Cancer Prevention
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• 제17권10호
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• pp.4615-4621
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• 2016

Background: There has not been a general estimation about survival rates of breast cancer cases in Iran. Therefore, the present study aimed to assess survival using a meta-analysis. Materials and Methods: International credible databases such as Scopus, Web of Science, PubMed, Science direct and Google Scholar and Iranian databases such as Magiran, Irandoc and SID, from 1997 to 2015 were searched. All articles covering survival rate of breast cancer were entered into the study without any limits. Quality assessment of the articles and data extraction were performed by two researchers using the modified STROBE checklist, which includes 12 questions. Articles with scores greater than 8 were included in the analysis. A limitation of this meta-analysis was different methods for presenting of results in the papers surveyed. Results: A total of 21 articles with a sample of 12,195 people were analyzed. The one-year, three-year, five-year and ten-year survival rates of breast cancer in Iran were estimated to be 95.8% (94.6-97.0), 82.4% (79.0-85.8), 69.5% (64.5-74.5), 58.1% (39.6-76.6), respectively. The most important factors affecting survival of breast cancer were age, number of lymph nodes involved, size of the tumor and the stage of the disease. Conclusion: The five- and ten- year survival rates in Iran are lower than in developed countries. Conducting breast cancer screening plan support (including regular clinical examination, mammography), public training and raising awareness should be helpful in facilitating early diagnosis and increasing survival rates for Iranian women.

• Journal of Preventive Medicine and Public Health
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• 제43권2호
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• pp.185-192
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• 2010

Objectives: We conducted a meta-analysis to investigate the relationship between low external doses of ionizing radiation exposure and the risk of cancer mortality among nuclear power plant workers. Methods: We searched MEDLINE using key words related to low dose and cancer risk. The selected articles were restricted to those written in English from 1990 to January 2009. We excluded those studies with no fit to the selection criteria and we included the cited references in published articles to minimize publication bias. Through this process, a total of 11 epidemiologic studies were finally included. A publication bias was tested for using Egger's test. The homogeneity test was performed before the integration of each of the standardized mortality ratios (SMRs) and the result proved that the studies were heterogeneous. Results: We found significant decreased deaths from all cancers (SMR = 0.75, 95% CI = 0.62 - 0.90), all cancers excluding leukemia, solid cancer, mouth and pharynx, esophagus, stomach, rectum, liver and gallbladder, pancreas, lung, prostate, lymphopoietic and hematopoitic cancer. The findings of this meta-analysis were similar with those of the 15 Country Collaborative Study conducted by the International Agency for Research on Cancer. A publication bias was found only for liver and gallbladder cancer (p = 0.015). Heterogeneity was observed for all cancers, all cancers excluding leukemia, solid cancer, esophagus, colon and lung cancer. Conclusions: Our findings of low mortality for stomach, rectum, liver and gallbladder cancers may explained by the health worker effect. Yet further studies are needed to clarify the low SMR of cancers, for which there is no useful screening tool, in nuclear power plant workers.

• 한국ITS학회 논문지
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• 제21권4호
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• pp.167-189
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• 2022

SAE 기준 자율주행 레벨 2, 3의 경우 완전 자율주행이 불가능하므로 주행에 있어 제어권 전환 과정이 필수적이며, 제어권 전환 소요시간은 자율주행시스템의 안전성을 결정하는 가장 중요한 요소이다. 이에 따라 제어권 전환 소요시간에 대한 연구가 활발히 진행되고 있으나, 각 연구는 독립적으로 시행되어 다양한 연구 결과를 통합한 일반적인 결론 도출이 필요한 실정이다. 따라서, 본 연구는 개별 연구 결과를 통합해서 통합적인 의견을 제시하는 메타분석 기법을 사용하여 제어권 전환 소요시간에 영향을 주는 요인을 분석하였다. 메타분석 결과, 총 10개의 영향요인이 선정되었으며 대부분이 비운전 업무 유형과 관련되어 있었다. 또한, 향후 제어권 전환 및 비운전 업무 연구 수행 방향성 측면에서 시사점을 제시하였다.

• Journal of Acupuncture Research
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• 제28권6호
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• pp.1-17
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• 2011

Objectives : This study aimed to review randomized controlled trials of acupuncture performed in South Korea that used sham acupuncture as a control group. Methods : The following databases were searched through the end of September 2011: Koreanstudies information service system (KISS), Korean medical database (KMbase), national discovery OR science leaders (NDSL), oriental medicine advance searching integrated system (OASIS), and research information service system (RISS). The following search terms were used: acupuncture AND (sham or placebo). The reference lists of searched articles and Korea institute of oriental medicine (KIOM) reports(2005~2009) were identified. The following data were extracted: year/first author, disease, number of participants, blinding, intervention, outcome, and result. Where appropriate, we performed meta-analysis. The methodological quality was assessed according to the Jadad scale and 'risk of bias' by Cochrane Handbook procedure. Results : Twenty-nine studies were included in this review. In eighteen studies, penetrating sham controls were used as the control intervention, whereas the remaining eleven studies adopted non-penetrating sham controls such as the Park Sham Device or blunt auricular acupuncture. Nine studies showed statistically significant difference in outcomes. Twelve studies concerning insomnia after stroke, chronic tension-type headache, idiopathic Parkinson's disease, Hwa-Byung, and smoking cessation were included in meta-analysis. A meta-analysis of insomnia after stroke only found significant difference(MD -4.31, 95% Cl -6.19 to -2.42, $p$<0.00001). In general, all of the studies showed low methodological quality(Jadad score: mean 2.1). Risk of bias by Cochrane Handbook procedure varied. Conclusions : The results of this study could not suggest conclusive evidence that acupuncture is more effective than sham acupuncture in several diseases. In the future, more studies with rigorous acupuncture trials using sham controls should be conducted.

• 콘크리트학회논문집
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• 제20권1호
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• pp.89-97
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• 2008

메타카올린을 시멘트 치환재로, 잔골재를 폐타이어 잔입자로 일부 치환시킴으로써 건축물 화재시 고강도콘크리트를 폭렬로부터 보호하는 한편, 내부에 배근된 철근의 온도 상승을 억제하는 방법의 검토 및 이들 재료를 혼입한 고강도콘크리트의 기초적 성상에 대하여 검토하였다. 검토 결과 메타카올린은 콘크리트 자체의 내화성을 향상시키며, 고강도콘크리트의 내부 팽창압의 상쇄 기능을 폐타이어 잔입자가 분담할 수 있는 것으로 확인되었다. 세부적으로는 메타카올린을 시멘트에 대해 4$\sim$8%의 중량비로, 폐타이어 잔입자를 0.6$\sim$3 mm의 입도 범위를 사용하며, 잔골재인 모래에 대해 5$\sim$10%의 중량비로 치환하는 것이 고강도콘크리트의 폭렬 방지를 위해 유효한 배합 수준인 것으로 분석되었다.

• 대한간호학회지
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• 제43권6호
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• pp.746-759
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• 2013

Purpose: Infrared thermometers are increasingly used as a convenient, non-invasive assessment method for febrile children. However, the diagnostic accuracy of the infrared thermometer for children has been questioned, particularly in relation to sensitivity and specificity. The aim of this study was to evaluate diagnostic accuracy of infrared thermometers in febrile children. Methods: Articles published between 1966 and 2012 from periodicals indexed in the Ovid Medline, Embase, CINAHL, Cochrane, KoreaMed, NDSL, KERIS and other databases were selected, using the following keywords: 'infrared thermometer'. The QUADAS-II was applied to assess the internal validity of the diagnostic studies. Selected studies were analyzed using meta-analysis with MetaDisc 1.4. Results: Nineteen diagnostic studies with high methodological quality, involving 4,304 children, were included. The results of meta-analysis showed that the pooled sensitivity, specificity and AUC (Area Under the Curve) of infrared tympanic thermometers in children over 1 year were 0.80 (95% CI 0.78, 0.81), 0.94 (95% CI 0.93, 0.95) and 0.95 respectively. However the diagnostic accuracy of infrared tympanic thermometers in children with hyperthermia was low. Conclusion: The diagnostic accuracy of infrared tympanic thermometer was similar to axillary and rectal thermometers indicating a need for further research to substantiate these findings in children with hyperthermia.