• Title/Summary/Keyword: Meta study

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A study on the duration of Ginkgo biloba extract effective in improving cognitive function in the elderly: A systematic review and meta-analysis

  • Cui, Fengjiao;Nawaz, Hadia;Kim, Hyun Kyung;Go, Gwang-woong
    • Korean Journal of Food Science and Technology
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    • v.54 no.4
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    • pp.403-413
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    • 2022
  • Evidence regarding the efficacy of Ginkgo biloba extract on cognitive function has been contentious. This study evaluated the effective period of G. biloba intake to improve cognition in the elderly. PubMed, EMBASE, Cochrane, Web of Science, and PsycArticles databases were searched for short-listing relevant studies. Twenty-five studies fulfilled the inclusion criteria. Cognitive efficacy was assessed based on the duration of intervention. G. biloba intake for 3-6 months statistically significantly affected cognitive function (SMD= -0.21; 95% CI -0.39, -0.03; p=0.02). However, the improvement in activities of daily living (ADLs) was not statistically significant. Thus, G. biloba intake for more than three months improves cognition in the elderly people with cognitive impairment and AD dementia without any safety risk. Intake for up to six months does not improve ADLs significantly in mild to moderate dementia patients.

Analysis of the Prior Studies on the Theory of International Trade (무역이론에 관한 연구동향 분석)

  • Taek-Dong Yeo
    • Korea Trade Review
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    • v.45 no.6
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    • pp.181-205
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    • 2020
  • International trade theory is largely divided into the pure theory of international trade and the theory of trade policy. The pure theory of international trade is an academic field that conducts research related to the trade flow of goods and services between countries and the movement of production factors across borders. Meanwhile, the theory of trade policy studies the positive and normative aspects of trade policy which a government adopts to achieve its policy goals. In this study, about 230 papers in the field of international trade theory published in the Korea Trade Review over the past 45 years (1975~2019) are examined in meta analysis by period and subject. First, this study provides the main research subjects of international trade theory, and historically reviews the overall development of trade theory by paying attention to the core and pioneering papers, domestic and foreign. Second, the publications in the field of trade theory are classified by subject, and the domestic and foreign research trends are also examined for each subject with the analysis of major publication of this Journal.

Meta Analysis on the Trade Settlement Study and Research Outlook (무역결제 분야 연구의 메타분석과 전망)

  • Hee-Jung Yeo
    • Korea Trade Review
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    • v.46 no.2
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    • pp.371-387
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    • 2021
  • This paper analyzed 110 papers related to the field of trade settlement published in the Korea Trade Review for 40 years from 1980 to 2019. This study tried to provide an insight on research topics and to suggest future research directions. The papers were analyzed according to the detailed topics of trade settlement. Research trends were identified every ten years by investigating the most frequently used titles and keywords. The analysis found that the direction of the research changed in line with the changes in trade settlement practices. Future research lies in the field of electronicization of traditional settlement methods, search for alternative settlement methods, individual international microtransaction and trade fraud.

Ultrasonography for Facial Nerve Palsy: A Systematic Review and Meta-Analysis Protocol

  • Seojung Ha;Bo-In Kwon;Joo-Hee Kim
    • Journal of Acupuncture Research
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    • v.41 no.1
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    • pp.63-68
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    • 2024
  • Background: Facial nerve palsy presents a significant healthcare challenge, impacting daily life and social interactions. This systematic review investigates the potential utility of ultrasonography as a diagnostic tool for facial nerve palsy. Methods: Electronic searches will be conducted across various databases, including MEDLINE, EMBASE, CENTRAL (Cochrane Central register of Controlled Trials), CNKI (China National Knowledge Infrastructure), KMBASE (Korean Medical Database), ScienceON, and OASIS (Oriental Medicine Advanced Searching Integrated System), up to February 2024. The primary outcome will focus on ultrasonography-related parameters, such as facial nerve diameter and muscle thickness. Secondary outcomes will encompass clinical measurements, including facial nerve grading scales and electrodiagnostic studies. the risk of bias in individual study will be assessed using the Cochrane Risk of Bias assessment tool, while the grading of recommendations, assessment, development, and evaluations methodology will be utilized to evaluate the overall quality of evidence. Conclusion: This study aims to review existing evidence and evaluate the diagnostic and prognostic value of ultrasonography for peripheral facial nerve palsy.

Vitamin D Receptor BsmI Polymorphism and Colorectal Cancer Risk: an Updated Analysis

  • Yu, Kun;Yang, Jing;Jiang, Yan;Song, Run;Lu, Qing
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.12
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    • pp.4801-4807
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    • 2014
  • Background: Previous studies have investigated the association between the vitamin D receptor (VDR) BsmI polymorphism and colorectal cancer (CRC) susceptibility, but the results were conflicting. The aim of this study is to quantitatively summarize the relationship between this polymorphism and CRC risk. Materials and Methods: Two investigators independently searched the Medline, Embase, China National Knowledge Infrastructure (CNKI) and Chinese Biomedicine databases for studies published before November 2013. Summary odds ratios (ORs) and 95% confidence intervals (95%CIs) for VDR BsmI polymorphism and CRC were calculated in a fixed-effects model (the Mantel-Haenszel method) and a random-effects model (the DerSimonian and Laird method) when appropriate. Results: This meta-analysis included 14 case-control studies, which included 10,822 CRC cases and 11,779 controls. Overall, the variant genotype (BB) of the BsmI was associated with a lower CRC risk when compared with the wild-type bb homozygote (OR=0.66, 95%CI: 0.49-0.88). Similarly, a decreased CRC risk was also found in the dominant and recessive models. When stratifying for ethnicity, source of controls, and study sample size, associations were observed among Caucasians, population-based studies and studies with large study sample size (>1000 subjects). Limiting the analysis to the studies within Hardy-Weinberg equilibrium, the results were persistent and robust. No publication bias was found in the present study. Conclusions: This updated meta-analysis suggests that the VDR BsmI polymorphism may be associated with a moderate protective effect against CRC.

An Investigation of Chemyon on Consumption Behavior of Asian and Western Consumers: Cross-Cultural Comparative Approach (체면 관점에서 본 동서양 소비자들의 소비행동에 관한 고찰: 비교문화 접근방법)

  • KIM, Young-Doo
    • The Journal of Industrial Distribution & Business
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    • v.10 no.5
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    • pp.37-47
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    • 2019
  • Purpose - It is well known that chemyon, referred to by Westerners as face, naturally penetrates the daily life of Asians and influences their cognition, emotion, and behavior. Studies related to chemyon have been conducted in marketing and consumer behavior fields (e.g., luxury products or brands, service failure and recovery, brand preferences, consumer decision making, wedding ceremony, gift giving). A bulk of studies demonstrate that chemyon influences consumption behavior in Asian consumers. Although chemyon significantly influences consumption behavior of Asian consumers, it is also a cultural phenomenon that is not completely explained within the Western viewpoint. Whereas a number of researchers have approached cross-cultural studies of Asian and Western consumers, a limited number of studies have examined it from the perspective of chemyom. The purpose of this study is to compare the phenomenon that chemyon (face) not only affects the consumption behavior of Asia and the West universally (pan-culturally), but also distinctively (culture-specifically). That is, the purpose of this study is to describe that chemyon (face) is not only a culture-specific phenomenon but also a universal phenomenon in the consumption behavior of Asian and Western consumers, even though the extent that chemyon (face) impacts consumption behavior is differentiated. This study aims to understand commonalities and differences between Asian and Western consumption behavior in terms of chemyon (face), and to suggest how to enhance marketing effectiveness in a global market based on understanding the consumption behavior of Asia and the West. Research design, data, and methodology - Using systematic literature review and meta-analysis, this study investigates consumption behavior of Asian and Western consumers from the perspective of chemyon (face). Systematic literature review was used to compare face (chemyon) consumption of Western consumers with that of Asian consumers. To verify systematic literature review, meta-analysis was also accomplished. Results - First, the influence of face (chemyon) on consumption behavior is observed in Western consumers as well as Asian consumers. Second, Asian consumers are more influenced by face (chemyon) than Western consumers. Conclusions - Overall, chemyon (face) can affect the consumption behavior of Asians as well as the consumption behavior of Westerners.

The Effects of Exercise Program on Pain and Balance ability in Patients with Total Knee Replacement : Meta-analysis

  • Park, Se-Ju
    • Journal of the Korea Society of Computer and Information
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    • v.26 no.5
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    • pp.119-126
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    • 2021
  • This study attempted to systematically and comprehensively analyze individual studies in which exercise program on total knee replacement patients. The electronic database for literature search used the Korean educational Academic Information (RISS), Korean Academic Information (KISS) and Nuri Media (DBPIA). We investigated a prior study of exercise program applied to total knee replacement patients from 2015 to February 2021. For meta-analysis, effect size of each individual study was extracted using R project for Statistical computing version 4.0.3. Rob 2.0 tool, developed by the Cochrane group, was used to evaluate the quality of each individual study. The overall effect size exercise program with pain and balance was 0.99 (95% CI=0.53-1.44), which was significantly different than large effect size (p<0.05). The sub-group for pain was analyzed, for effect size of 0.62 and the effect size of balance scale(timed up and go test) was 1.00. Through these results, it was found that exercise program is an effective exercise for total knee replacement patients, and further research is needs.

Recent Research Trends of Acupuncture for Wrinkle Treatment (주름 개선을 위한 침 연구의 현황분석)

  • Jung, Hyeon-Suk;Kim, Tae-Jun;Park, Ji-Yeun
    • Korean Journal of Acupuncture
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    • v.38 no.2
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    • pp.62-74
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    • 2021
  • Objectives : The aim of this study is to analyze the effect of acupuncture and the details of acupuncture treatment methods on skin wrinkles. Methods : Search was conducted in Pubmed, KISS, and NDSL databases for acupuncture studies on skin wrinkles. The detailed therapeutic techniques of acupuncture used for skin wrinkles and the effect of acupuncture on skin wrinkle improvement were analyzed. Then, the study results using the same indicator were compared through meta-analysis in order to compare the effects of acupuncture with the control group. The quality of randomized controlled trials (RCTs) was assessed using the risk of bias (ROB) assessment tool (Ver. 1.0, Cochrane Collaboration). Results : A total of 10 RCTs and 19 case series were included in this study. The most frequently used therapeutic technique for skin wrinkle improvement was Microneedle therapy system (MTS, n=19), and they were mostly used with aesthetic solutions (13 out of 19 studies). Skin wrinkle related indexes were most commonly used to evaluate skin wrinkle improvement (n=14). Panax Ginseng pharmacopuncture showed the most remarkable effect in improving the range of skin wrinkles and the depth of skin wrinkles. MTS+epidermal growth factor improved the levels of skin hydration, skin elasticity, and variation of skin pigment the most. MTS+Endothelial precursor cell improved the number of skin melanin the most. Three RCTs included in the meta-analysis showed moderate ROB on average. Conclusions : Acupuncture treatment was effective in improving skin wrinkles. However, a precise study design using unified indicators and appropriate controls needs to be performed in further studies in order to establish more convincing evidence of the effectiveness of acupuncture for improving skin wrinkles.

Association between polycystic ovary syndrome and risk of attention-deficit/hyperactivity disorder in offspring: a meta-analysis

  • Maleki, Azam;Bashirian, Saeid;Soltanian, Ali Reza;Jenabi, Ensiyeh;Farhadinasab, Abdollah
    • Clinical and Experimental Pediatrics
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    • v.65 no.2
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    • pp.85-89
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    • 2022
  • Background: There is evidence of a relationship between prenatal excess androgen exposure and central nervous developmental problems and attention-deficit/hyperactivity disorder (ADHD) in the offspring of mothers with polycystic ovary syndrome (PCOS). Purpose: Here we aimed to use a meta-analysis to investigate whether the offspring of mothers with PCOS are at an increased chance of developing ADHD. Methods: Three main English databases were searched for articles published through December 2020. The Newcastle-Ottawa Scale was used to assess study quality. Study heterogeneity was determined using I2 statistics and publication bias was assessed using Begg and Egger tests. The results are presented as odds ratio (OR) and relative ratio (RR) estimates with 95% confidence intervals (CIs) using a random-effects model. Results: Six articles (3 cohort and 3 case-control studies; 401,413 total ADHD cases) met the study criteria. Maternal PCOS was associated with an increased risk of ADHD in the offspring based on OR and RR (OR, 1.42; 95% CI, 1.27-1.57) and (RR, 1.43; 95% CI, 1.35-1.51), respectively. There was no heterogeneity among the included articles based on OR (I2=0.0%, P=0.588) and RR (I2=0.0%, P=0.878). Conclusion: Our study showed that maternal PCOS is a risk factor for ADHD. Therefore, screening their offspring for ADHD should be considered part of the comprehensive clinical care of women with PCOS.

Antimicrobial Activity of Propolis Extract and Their Application as a Natural Preservative in Livestock Products: A Meta-Analysis

  • Andre, Andre;Arief, Irma Isnafia;Apriantini, Astari;Jayanegara, Anuraga;Budiman, Cahyo
    • Food Science of Animal Resources
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    • v.42 no.2
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    • pp.280-294
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    • 2022
  • This study aimed to evaluate the effectiveness of propolis extract as a natural preservative for livestock products in term of chemical and microbiological characteristics by meta-analysis. The stages carried out in this study were identification, selection, checking suitability, and the resulting selected articles were used in the meta-analysis. The selection results obtained a total of 22 selected journal articles consisting of 9 articles for analysis of the antimicrobial activity of propolis extract and 13 articles for analysis of the chemical and mirobiological characteristics of livestock products. The articles were obtained from electronic databases, namely Science Direct and Google Scholar. The model used in this study is the random-effect model involving two groups, control and experimental. Heterogeneity and effect size values were carried out in this study using Hedge's obtained through openMEE software. Forest plot tests and data validation on publication bias was obtained using Kendall's test throught JASP 0.14.1 software. The results showed that there is a significant relationship between propolis extract with the results of the antimicrobial activity (p<0.05). In addition, the results of the application of propolis extract on the livestock products for the test microbes and the value of thiobarbituric acid reactive substances (TBARs) showed significant results (p<0.05). Conclusion based on the random-effect model on the effectiveness of antimicrobial activity of propolis extract and their apllication as a natural preservative of the chemical and microbiological characteristics of livestock products is valid by Kendall's test (p>0.05). Propolis in this case effectively used as natural preservatives in livestock products.