• Title/Summary/Keyword: Meta study

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The anti-diabetic effect of propolis using Hedges' standardized mean difference (헤지의 표준화된 평균차를 이용한 프로폴리스의 항-당뇨 효과)

  • Kim, Mi-Jin;Choi, Ki-Heon
    • Journal of the Korean Data and Information Science Society
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    • v.21 no.3
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    • pp.447-459
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    • 2010
  • The present study was carried out to summarize the effect of propolis in the diabetic rats by meta-analysis related studies. The association measure to test effect of propolis was Hedges's standardized mean difference between group of rats induced streptozotocin(STZ) or alloxan and group of rats induced STZ or alloxan treated with propolis about the considered 4 effect factors. In this particular fixed-effect model, blood glucose, Cholesterol, Triglyceride were significantly reduce. The case of heterogenous variable such as body weight, blood glucose, cholesterol, triglyceride, random-effect model was applied. In this model, blood glucose, triglyceride were decreased significantly in propolis treated group. According to the meta-regression analysis, period of injection was significant for body weight and blood glucose, cholesterol.

Lack of Association between the hOGG1 Ser326Cys Polymorphism and Gastric Cancer Risk: a Meta-analysis

  • Li, Bai-Rong;Zhou, Guo-Wu;Bian, Qi;Song, Bin
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.4
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    • pp.1145-1149
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    • 2012
  • Aim: To clarify any association between the hOGG1 Ser326Cys polymorphism and susceptibility to gastric cancer. Methods: A meta-analysis based on 11 eligible case-control studies involving 5,107 subjects was carried out to summarize the data on the association between hOGG1 Ser326Cys polymorphism and gastric cancer risk. Results: No association was found between hOGG1 Ser326Cys polymorphism and gastric cancer risk (dominant model: OR = 0.95, 95% CI: 0.83-1.09, p = 0.486, ph (p values for heterogeneity) = 0.419; additive model: OR = 1.02, 95% CI: 0.81-1.30, p = 0.850, ph = 0.181; recessive model: OR = 1.09, 95% CI: 0.80-1.48, p = 0.586, ph = 0.053). Subgroup analysis based on ethnicity (Asian and Caucasian) and smoking status (ever smoker and never smoker) did did notpresent any significant association. Sensitivity analysis did not perturb the results. Conclusions: This study strongly suggested there might be no association between the hOGG1 Ser326Cys polymorphism and gastric cancer risk. However, larger scale studies are needed for confirmation.

Association of Reduced Immunohistochemical Expression of E-cadherin with a Poor Ovarian Cancer Prognosis - Results of a Meta-analysis

  • Peng, Hong-Ling;He, Lei;Zhao, Xia
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.5
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    • pp.2003-2007
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    • 2012
  • Purpose: E-cadherin is a transmemberane protein which is responsible for adhesion of endothelial cells. The aim of our study was to assess existing evidence of associations between reduced expression of E-cadherin and prognosis of ovarian cancer with a discussion of potential approaches to exploiting any prognostic value for improved clinical management. Methods: We conducted a meta-analysis of 9 studies (n=915 patients) focusing on the correlation of reduced expression of E-cadherin with overall survival. Data were synthesized with random or fixed effect hazard ratios. Results: The studies were categorized by author/year, number of patients, FIGO stage, histology, cutoff value for E-cadherin positivity, and methods of hazard rations (HR) estimation, HR and its 95% confidence interval (CI). Combined hazard ratios suggested that reduced expression of E-cadherin positivity was associated with poor overall survival (OS), HR= 2.10, 95% CI:1.13-3.06. Conclusion: The overall survival of the E-cadherin negative group with ovarian cancer was significant poorer than the E-cadherin positive group. Upregulation of E-cadherin is an attractive therapeutic approach that could exert significant effects on clinical outcome of ovarian cancer.

Synthesis of Primary Studies Related to Clothing Involvement by Meta-analysis (의복관여 효과에 대한 메타분석)

  • Lee, Jongnam;Yu, Haekyung
    • Journal of the Korean Society of Clothing and Textiles
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    • v.37 no.3
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    • pp.386-398
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    • 2013
  • This study analyzes the effect of clothing involvement using meta-analysis. Metal-analysis (the analysis of analyses) is widely used in various academic areas to integrate individual empirical studies and generalize the knowledge of a specific research field. Previous studies regarding clothing involvement published since 1990 were researched from the KISS database using clothing involvement and fashion involvement as a keyword; subsequently, 127 articles were identified. Studies that had insufficient statistics or included clothing involvement as a moderating (or intervening variable) were eliminated; subsequently, 36 articles provided a total of 75 data sets that were used for the final analysis. Dependent variables were grouped into 10 categories to compare the differences between high and low involvement groups. The effect size of clothing involvement was large in non-personal information source; however, it was small in utility, brand royalty and quality. In the 7 categories of relational studies that showed homogeneity, the relation size regarding conformity was smaller than the personal information source.

A meta-analysis on the effects of the differentiated instruction in mathematics (수학과 수준별 수업의 효과에 대한 메타분석)

  • Kim, Sun Hee
    • The Mathematical Education
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    • v.54 no.4
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    • pp.335-350
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    • 2015
  • The purpose of this study was to investigate the effectiveness of the differentiated instruction in mathematics by a meta-analysis. Among the studies conducted for last twenty three years, the relevant 49 research articles were selected, 80 effect sizes were calculated for the cognitive domain and 70 effect sizes for the affective domain. Effect sizes were analyzed with school levels, student level, group organization method such as homogeneous vs. heterogeneous, class transfer and adjusting class sizes for each cognitive domain and affective domain. The results are as the followings: In the cognitive domain, the overall effect size of the differentiated instruction produced a medium effect(effect size=0.68, U3=75.17%). The differentiated instruction showed the highest effect size on elementary school and middle school, mid level students, heterogeneous group, class transfer and not adjusted class size. And in the affective domain, the overall effect size of the differentiated instruction produced a low effect(effect size=0.36, U3=65.36%). The differentiated instruction showed the highest effect size on elementary school, mid level students, and heterogeneous group. Thus the differentiated instruction was proved to be effective in mathematics classes.

Tai-chi for Low back pain: Systematic Review (태극권 운동이 요통에 미치는 영향 : 체계적 문헌 고찰)

  • Choo, Su-Cheol;Kim, Kyu-Jin;Kim, Eun-Bi;Hwang, Eui-Hyoung
    • The Journal of Churna Manual Medicine for Spine and Nerves
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    • v.13 no.1
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    • pp.35-44
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    • 2018
  • Objectives: To determine the effectiveness of Tai-chi in treatinglow back pain. Methods: We searched 9 electronic databases(Pubmed, CAJ, EMBASE, Cochrane Library, Web of Science, KISS, KISTI, NDSL, and RISS) till April 2018 and included randomized controlled trials(RCTs) that used Tai-chi for lower back pain treatment. The methodological quality of each RCT was assessed usingthe Cochrane risk of bias tool. Results: As per the inclusion criteria, 5 RCTswere found to be eligible for our review. These studies were divided into 4 groups and meta-analysis was performed. The meta-analysis of 1 study showed favorable results regardingthe use of Tai-chi. Twostudies showed favorable results regardingthe use of Tai-chi with Tuina rather than Tuina alone. All studies were observed to have a high risk of bias. Conclusions: There is limited evidence available to support the effectiveness of Tai-chi in relieving low back pain;hence, additionalwell-designed RCTs should be encouraged for better evidence.

Analysis of trusses by total potential optimization method coupled with harmony search

  • Toklu, Yusuf Cengiz;Bekdas, Gebrail;Temur, Rasim
    • Structural Engineering and Mechanics
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    • v.45 no.2
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    • pp.183-199
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    • 2013
  • Current methods of analysis of trusses depend on matrix formulations based on equilibrium equations which are in fact derived from energy principles, and compatibility conditions. Recently it has been shown that the minimum energy principle, by itself, in its pure and unmodified form, can well be exploited to analyze structures when coupled with an optimization algorithm, specifically with a meta-heuristic algorithm. The resulting technique that can be called Total Potential Optimization using Meta-heuristic Algorithms (TPO/MA) has already been applied to analyses of linear and nonlinear plane trusses successfully as coupled with simulated annealing and local search algorithms. In this study the technique is applied to both 2-dimensional and 3-dimensional trusses emphasizing robustness, reliability and accuracy. The trials have shown that the technique is robust in two senses: all runs result in answers, and all answers are acceptable as to the reliability and accuracy within the prescribed limits. It has also been shown that Harmony Search presents itself as an appropriate algorithm for the purpose.

A Study on Data Migration using XMDR-DAI (XMDR-DAI를 이용한 데이터 이주 기법에 관한 연구)

  • Moon, Seok-Jae;Jung, Gye-Dong;Choi, Young-Keun
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.13 no.12
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    • pp.2707-2718
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    • 2009
  • Enterprises saved and controled data using individual and various database which were occurred on business. The saved data that were existed in the database were approached by business processing for specified achievement of service's aims and were occurred frequently data migration. This research propose the data migration method using XMDR-DAI(eXtended Meta-Data Registry-Data and Integration) that were occurred by approaching and integration in the process of business processing based on sql query.

A Study on the EDB System Structure for Integration of Design Data (설계 DATA 의 통합을 위한 EDB 시스템의 구조에 관한 고찰)

  • Kim, C.H.;Lim, C.K.;Chung, W.Y.;Kim, W.S.
    • IE interfaces
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    • v.7 no.3
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    • pp.137-145
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    • 1994
  • 현재까지의 EDB 시스템이 Data를 중심으로 한 관리나 프로세스 관리 같은 것들을 프로그램으로는 Hard Coding되어 있었던 관계로 인하여 단위업무의 성력화 또는 순수 데이터 관리 측면에서는 효율성을 가졌으나, 기업의 무한경쟁시대에 생존 수간으로서 행해지고 있는 BPR(Business Process Restructure) 또는 CE(Concurrent Engineering)에 대응 할 수 있는 유연성이 결여되어 있었다. 따라서 프로세스나 데이터에 관련된 규칙 또는 데이터가 있는 위치등과 같은 프로세스 및 데이터의 속성에 대한 정보를 Meta Database에 저장하여 보다 유연성이 있고 일관성 있게 데이터를 취급해 줄 필요성이 대두 되었다. 이러한 Meta Database를 사용자 시각에서 바라보면 프로세스가 변화 된다하더라도 일관된 실제 작업을 할 수 있을 것이다. 즉, 사용자는 자신이 사용하는 EDB의 단위 Application을 사용하면 새로 정의된 프로세스에 따라 자신의 데이터를 Release하고 시방변경, 삭제, 의뢰 등을 처리 할 수 있을 것이다. 따라서 현재의 EDB 시스템들의 개발이 전체의 개발 프로세스 중에서 일부만을 부분부문으로 개발하고 통합 할 뿐 실제 일관된 데이터의 유지나 공유가 매우 힘들었던 것을 부분적인 형태로 시스템이 구축된다하더라도 Meta Database를 통하여 개발 프로세스 전반에 걸친 다양한 PART 시스템간의 데이터 공유를 가능하게 할 수 있는 EDB 시스템구조에 대해 설명하고자 한다.

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Comparison between Cementless and Cemented Bipolar Hemiarthroplasty for Treatment of Unstable Intertrochanteric Fractures: Systematic Review and Meta-analysis

  • Yoo, Jun-Il;Cha, Yong-Han;Kim, Kap-Jung;Kim, Ha-Yong;Choy, Won-Sik;Hwang, Sun-Chul
    • Hip & pelvis
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    • v.30 no.4
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    • pp.241-253
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    • 2018
  • Purpose: This study was conducted to compare cemented and cementless bipolar hemiarthroplasty in elderly patients with unstable intertrochanteric fractures via meta-analysis and systematic review of relevant studies. Materials and Methods: Systematic review and meta-analysis were performed on 31 available clinical studies; 19 of these studies used cemented stems, 12 used cementless stems, one used both types of stems, and two studies involved a comparative analysis of both stem types. Results: There were statistically significant differences in rates of leg length discrepancy (LLD) greater than 1 cm between the cemented (event rate, 0.089) and cementless groups (event rate, 0.015 and 0.047; P=0.03). Conclusion: Cemented bipolar hemiarthroplasty and cementless bipolar hemiarthroplasty performed on elderly patients with unstable intertrochanteric fracture revealed similar mortality and complication rates; however, the rate of LLD greater than 1 cm was significantly higher in the cemented group compared with the cementless group.