• Journal of Korean Society of Industrial and Systems Engineering
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• v.39 no.3
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• pp.83-89
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• 2016

The group formation problem of the machine and part is a critical issue in the planning stage of cellular manufacturing systems. The machine-part grouping with alternative process plans means to form machine-part groupings in which a part may be processed not only by a specific process but by many alternative processes. For this problem, this study presents an algorithm based on self organizing neural networks, so called SOM (Self Organizing feature Map). The SOM, a special type of neural networks is an intelligent tool for grouping machines and parts in group formation problem of the machine and part. SOM can learn from complex, multi-dimensional data and transform them into visually decipherable clusters. In the proposed algorithm, output layer in SOM network had been set as one-dimensional structure and the number of output node has been set sufficiently large in order to spread out the input vectors in the order of similarity. In the first stage of the proposed algorithm, SOM has been applied twice to form an initial machine-process group. In the second stage, grouping efficacy is considered to transform the initial machine-process group into a final machine-process group and a final machine-part group. The proposed algorithm was tested on well-known machine-part grouping problems with alternative process plans. The results of this computational study demonstrate the superiority of the proposed algorithm. The proposed algorithm can be easily applied to the group formation problem compared to other meta-heuristic based algorithms. In addition, it can be used to solve large-scale group formation problems.

• Journal of Oriental Neuropsychiatry
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• v.28 no.3
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• pp.217-230
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• 2017

Objectives: This study was conducted to review studies on somatization disorder in traditional Chinese medicine. Methods: We reviewed studies in the China National Knowledge Infrastructure (CNKI) to 2017. Keywords were 軀體化障碍, Somatization disorder, somatic symptom disorder. We included Randomized Controlled Trial (RCT), and excluded non-Randomized Controlled Trial (nRCT), non-related somatization disorder or traditional Chinese medicine, non-clinical trials, dissertations for degrees. Jadad scale and Cochrane Library's Risk of Bias (RoB) were used for assessment of the quality of studies. Results: Twelve studies were selected. The Chinese Classification of Mental Disorders-3 (CCMD-3) was most frequently used as diagnostic criteria for somatization disorder. As for outcome measurement, Hamilton Rating Scale for Depression (HAMD) was used most commonly. Meta-analysis of 10 studies revealed effective rate of Chinese Herbal Medicine groups (CHM) was significantly higher than Western Medicine groups (WM) (RR: 1.14, 95% CI: 1.02 to 1.27, p=0.02, $I^2=40%$). There was no significant difference in effective rate of CHM+WM and WM (RR: 1.12, 95% CI: 0.84 to 1.49, p=0.46, $I^2=83%$). And also, effective rate of Acupuncture group (Acu) revealed no significant difference compared to that of WM (RR: 1.17, 95% CI: 0.95 to 1.44, p=0.13, $I^2=84%$). For HAMD, there was significant difference in CHM vs, WM group and Acu vs. WM group. Quality of selected 12 RCTs was low. Conclusions: Therapies practiced in traditional Chinese medicine may be effective options for somatization disorder. treatment. For further clinical studies in Korean medicine, this study could be groundwork for development of diagnosis and treatment on somatization disorder.

• Journal of Korean Clinical Nursing Research
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• v.23 no.3
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• pp.376-387
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• 2017

Purpose: This study was to systematically review the contents and effects of nurse-led transitional care programs for discharged patients from hospital to home. Methods: Randomized controlled trials published between 2005 and 2015 were searched in Pubmed, Embase, Cochrane(Central Register of Controlled Trials) and CINAHL. Data were analyzed using Cochrane Review Manager(Revman) software 5.3. Results: Nine studies were selected and analyzed. Patient assessment, education and discharge planning were included in pre-discharge phase. Referring, communication and care planning were performed by nurses in transition phase. Home and phone visits, monitoring and multidisciplinary advices were included in post-discharge phase. Various outcome measures such as hospital utilization(30 days readmission and emergency department visit), quality of life, and cost were used to identify effectiveness of nurse-led transitional care programs. 30 days readmission(OR=.73, 95% CI 0.54, 0.98; p=.03) and emergency department visit(OR=.67, 95% CI 0.50, 0.88; p=.005) were statistically significant in meta-analysis. However, participant blinding was not done in seven studies which put at the risk of performance bias. Conclusion: The results indicated that nurse-led transitional care program is effective in reducing unnecessary hospital utilization. Nevertheless, small sample size and risk at performance bias are the limitation of this study. Thus, we suggest that well-designed randomized controlled trials need to be conducted.

• Journal of the Korea Convergence Society
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• v.8 no.2
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• pp.269-276
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• 2017

The purpose of this study is to review empirical research on Form-focused instruction (FFI) in Korean language education from a critical perspective to better understand the effectiveness of FFI. To achieve this goal, several databases were searched to locate relevant experimental and quasi experimental studies published in peer-reviewed journals. Out of 66 studies collected, 12 studies met the inclusion criteria. The studies were then analyzed in terms of subjects, target grammar, treatment, measurement, and the learning outcomes of different techniques. In general, several types of FFI techniques had positive effects on helping learners acquire Korean as a second or foreign language. The results of the study will provide a conceptual framework which identifies the major factors affecting the effectiveness of FFI. The results will also be able to inform future meta-analytical research of existing studies.

• Journal of Korean Academy of Nursing
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• v.26 no.2
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• pp.372-386
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• 1996

Recently, the ratio of elderly in the population are fast growing due to socio-economical development and the better medical service. Proportionally, the health problems in elderly are increasing, too. Medical professionals must try so that the elderly have the better life through health promotion and disease prevention as well as disease treatment. This study evaluated the effect of walking exercise program on the cardiorespiratory function and the flexibility in the elderly women. The design of research was one group pretest-posttest design. The subjects were eleven elderly women over sixty years old to live in K-city, Kyonggi-do. The type of exercise was walking, which was the most popular exercise in questionnaire. The exercise intensity was 40％∼60％ of the target heart-rate by Karvonen's method and maintained by the heart-rate monitor. The exercise period was five weeks and the exercise frequency was three times per week. The exercise duration was forty minutes at first and gradually increased up to an hour. In order to evaluate the effect of walking exercise, we measured VO/sub₂ max, resting heart -rate, systolic/diastolic blood pressure, FVC, FEV/sub₁, the flexibility before and after the five week's exercise program. The data are analyzed by the paired t-test and Wilcoxon signed rank test using SAS package. The results are as follows : 1) The hypothesis that cardiorespiratory function will be improved was partly supported. In VO/sub₂ max（p＝0.0001）, resting heart-rate（p＝0.0030）, systolic/diastolic blood-pressure（p＝0.0387／ p＝0.0024）, there was significant difference. FVC and FEV/sub₁ were increased after the exercise, but there were no significant difference. 2) The hypothesis that the flexibility will be improved was supported. There was significant difference in the flexibility（p＝0.0140）. As the further study, it is necessary to reevaluate the effect with more refined design. We also need to try meta-analysis about the results of previous studies obtained in the experimental setting and compare our result obtained in the field setting with them.

• Journal of Advanced Navigation Technology
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• v.17 no.1
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• pp.123-131
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• 2013

If Industrial state-of-the-art technology that made through IT convergence should be to build safely environment that can protect then IT technology and manufacturing industry become convergence and a growth engine become stable positioning. In each industry, there has been a steady effort for the industrial security. However, they introduced only managerial/technical/physical countermeasures. Therefore, it is difficult to find a reference point as industrial security necessity, protecting coverage and things and so on. It is to lack that academic research in industrial security for protecting industrial technology. In detail, a clear definition lack for industrial security. And target range classification lack for industrial security studies. In this study, we redefined the concept of industry security through previous studies. Academic classification designed industrial security studies through delphi method. we analyzed industry security trends based industrial security studies classification and presented domestic industry research orientations.

• The Journal of the Korea Contents Association
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• v.18 no.2
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• pp.47-56
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• 2018

The aim of this study is investigate the research trends by analyzing the researches related to Korean and international genetics in oncology nursing. We conducted a text network analysis focusing on the key words presented in the abstracts of papers published in journals related to genetics in oncology nursing. Nurse, Cancer, Genetic, Patient, Knowledge, Care, and Genetic Test were identified as keywords and centralized keywords. As a result of studying research trends over time, researches including keywords such as information, care, and knowledge have increased since the completion of the Human Genome Project in 2003. Key words classified through the meta paradigm of nursing were health, nursing, human, environment order. This study is meaningful in that it can be used to identify trends in tumor genetic nursing research and to set the direction of development of nursing intervention for hereditary cancer patients.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.7
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• pp.258-264
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• 2018

This paper presents application of a differential search (DS) meta-heuristic optimization algorithm for optimal operation of a micro grid system. The DS algorithm simulates the Brownian-like random-walk movement used by an organism to migrate. The micro grid system consists of a wind turbine, a diesel generator, a fuel cell, and a photovoltaic system. The wind turbine generator is modeled by considering the characteristics of variable output. Optimization is aimed at minimizing the cost function of the system, including fuel costs and maximizing fuel efficiency to generate electric power. The simulation was applied to a micro grid system only. This study applies the DS algorithm with excellence and efficiency in terms of coding simplicity, fast convergence speed, and accuracy in the optimal operation of micro grids based on renewable energy resources, and we compared its optimum value to other algorithms to prove its superiority.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.16
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• pp.6905-6910
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• 2014

Background: The relation ofsurvivin gene expression to survival and surgical prognostic factors in the patients with endometrial carcinoma is unclear. Materials and Methods: In this study, 62 cases who were operated due to endometrial carcinoma were investigated between 2003 and 2011 in the the gynecological oncology clinic of Female Disease Training and Investigation Hospital of Etlik Zubeyde, Hanim, Turkey. Clinical and surgical prognostic factors were investigated by screening the records of these cases. With the standard streptavidin-biotin immune peroxidase method, cytoplasmic and nuclear expression of survivin was investigated in sections with specific antibodies (1:100, diagnostic Bio Systems, USA) primer. The aim was to elucidate any relation between survivin expression and defined prognostic factors and survival. Results: There was no statistically significant relationship between cytoplasmic and nuclear indexes identified for survivin and age, body mass index, the levels of preoperative hemoglobin, platelet and Ca 125, stage, grade, lymph node meastasis, the number of meta statical lymph nodes (total, paraaortic and pelvic), myometrial invasion, serosal invasion, adnexal involvement, the presence of acid in the first diagnosis, the involvement of omentum, the adjuvant treatment application of the cases, the presence of recurrence and rate of mortality (p>0.05). Statistical significance was noted for the presence of advanced stage lymph node metastasis (pelvic, paraaortic, pelvic and paraaortic), serosal involvement, positive cytology, lymph vascular space invasion, intra abdominal metastasis, and omentum involvement. When investigated the relation between cytoplasmic and nuclear survivin indexes and total survival, the result was not statistically significant (p>0.05). Conclusions: In our study, there was no statistically significant relationship between the rates of cytoplasmic and nuclear survivin expression with identified prognostic factors and total or non-disease survival.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.12
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• pp.7111-7116
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• 2013

Introduction: Trastuzumab, an HER2-targeting agents, has shown efficacy in metastatic HER2-positive breast cancer patients. Single-agent clinical trials have evaluated therapeutic regimens using trastuzumab for metastatic breast cancer patients. The aim of our study is to evaluate the efficacy and safety of trastuzumab in combination with chemotherapy or hormone therapy in HER2-positive metastatic breast cancer patients. Methods: A literature research was conducted in PubMed and to identify appropriate studies from relevant reviews. Randomized controlled trials comparing chemotherapy or hormone therapy regimens in combination with trastuzumab were eligible. Dadta on clinical outcomes, including safety, efficacy, and patient characteristics were collected. Results: Seven articles describing five trials were included in our systematic review and meta-analysis. Partners of trastuzumab included in trials were anthracycline, paclitaxel, docetaxel, anastrozole and letrozole. The addition of trastuzumab to chemotherapy improved the overall survival (HR=0.79, 95%CI 0.65-0.96), while to hormone therapy did not (HR=0.85 95%CI 0.56-1.30). All trastuzumab-containing regimens increased cardiac toxicity (RR=3.37, 95%CI 1.26-9.02) and grade III-IV adverse events. Conclusions: Our study supports the addition of trastuzumab to chemotherapy which is effective and tolerated for metastatic breast cancer with HER2+ patients. Of note, more adverse events will occur followed the use of trastuzumab, especially cardiac toxicity, with two treatment regimens.