• Title/Summary/Keyword: Meta study

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Analgesic efficiency of dexketoprofen trometamol in third molar surgery: a systematic review and meta-analysis

  • Bishwa Prakash Bhattarai;Diane Isabel Selvido;Dinesh Rokaya
    • Journal of Dental Anesthesia and Pain Medicine
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    • v.24 no.5
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    • pp.305-318
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    • 2024
  • This study aims to compare the analgesic efficacy of dexketoprofen trometamol (DT) with other analgesic drugs for pain relief after third molar surgery. The PubMed, Scopus, and Web of Science databases were searched to identify randomized controlled trials comparing DT with other analgesics for third molar surgery. The outcome measures were the sum of pain intensity differences (SPID), total pain relief (TOTPAR) at the 6th and 8th postoperative hours, time to rescue medication, and tolerability. In total, four studies met our inclusion criteria. A total of 660 third molar surgeries were performed: 365 in the DT group and 295 in the active control group. Compared to other analgesics, DT produced significantly better pain relief at the 6th postoperative hour: SPID (MD, 0.33; P = 0.01) and TOTPAR (MD, 0.41; P = 0.02). However, there were no statistically significant differences in the efficiency of pain relief at the 8th postoperative hour, time to rescue medication, or tolerability. Overall, a 25 mg dose produced the best results for pain relief. In conclusion, DT (25 mg) is a viable alternative to contemporary analgesics for pain relief after third molar surgery, particularly during the early postoperative period.

Black Lung Disease Among Coal Miners in Asia: A Systematic Review

  • Kurnia A. Akbar;Kraiwuth Kallawicha
    • Safety and Health at Work
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    • v.15 no.2
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    • pp.123-128
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    • 2024
  • Background: Coal miners are highly prone to occupational health risks, such as black lung disease. This study aims to assess the prevalence of black lung disease and the factors associated with black lung disease among coal miners in Asia. Method: This systematic review, conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines, searched through the scientific literature of the following databases: EBSCO, ScienceDirect, PubMed, and Scopus. We selected articles that studied black lung disease among coal miners from 48 countries in Asia and were published between 2014 and 2023. Article quality was evaluated using the Critical Appraisal Skills Program. Result: The seven articles that we review studied a total of 653,635 coal miners from various types of coal mines from three countries in Asia. Of these miners, 59,998 experienced black lung disease. Black lung disease is prevalent among 9.18% of coal miners in Asia, which is approximately four times higher than the worldwide prevalence. Common factors that influence black lung disease in Asia include age, years of dust exposure, smoking, drinking, working types, and sizes of mines, type of mines, respiratory functions, spirometry parameters, tenure, lack of attention to occupational health, inefficient surveillance, and weak occupational health service. Conclusion: Although the prevalence of black lung disease among coal miners in Asia is considerably high, it can be addressed through effective prevention measures, monitoring, control, and case reporting.

Predicting the impact of global warming on carbonation of reinforced concrete structures in Zambia and Japan

  • Wanzi A. Zulu;Miyazato Shinichi
    • Advances in concrete construction
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    • v.17 no.5
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    • pp.245-255
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    • 2024
  • The problem of carbonation-induced corrosion has become a concern in recent times, especially in the 21st century, due to the increase in global temperatures and carbon dioxide (CO2) concentration in the atmosphere possessing a significant threat to the durability of reinforced concrete (RC) structures worldwide, especially in inland tropical regions where carbonation is the most significant concrete degradation mechanism. Therefore, a study was conducted to predict the impact of global warming on the carbonation of RC structures in Lusaka, Zambia, and Tokyo, Japan. The Impact was estimated based on a carbonation meta-model that applies the analytic solution of Fick's 1st law using literature-based concrete mix design data and forecasted local temperature and CO2 concentration data over a 100-year period with relative humidity assumed constant. The results showed that CO2 diffusion increased between 17-31%, effecting a 40-45% rise in carbonation coefficient and a significant reduction in corrosion initiation time of 50-52% in the two cities. Moreover, for the same water-cement ratio, Lusaka showed almost twice higher carbonation coefficient values and one third shorter corrosion initiation time compared to Tokyo, mainly due to its higher temperature and low relative humidity. Additionally, the carbonation propagation depth at the end of 100 years was between 12-22 mm in Tokyo and 18-40 mm in Lusaka. These findings indicate that RC structures in these cities are at risk of rapid deterioration, especially in Lusaka, where they are more vulnerable.

Web3.0 Metaverse Business Model Innovation of Sports Media

  • Song, Minzheong
    • International Journal of Internet, Broadcasting and Communication
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    • v.16 no.3
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    • pp.64-76
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    • 2024
  • We study three sports media start-ups that seek to promote business model innovation (BMI) in which Web 3.0 and metaverse are converged. In results, LM starts from an innovative digital space platform offering a unique combination of virtual real estate, games, and non-fungible tokens (NFTs) which come with real-world earning potential. It creates value by integrating virtual real estate, training academies, blockchain games, and meta shops to offer a unique experience, capture value by offering monetization tools for buying and trading limited edition NFTs of favorite influencers from various sports leagues, offering access to premier real-world events and VIP game contests, and delivers value by building community to play games with favorite athletes or teams including trivia games, allowing fans to engage with their favorite athletes in a unique exclusive way. SL starts from the customizable digital identities especially for young sports fans like generation (gen) Z to play, hang out, and express themselves with their own avatars. SI starts from a leading Web3.0 metaverse innovator creating NFTs with the greatest athletes of all time, allowing athletes and creators to set up a profile and mint NFTs directly onto the blockchain. It tries to have the partnerships with great athletes revolutionizing the sports media industry to connect sports heroes and their super fans through an immersive, artistic, inspirational NFTs and unlockable content creating a sticky community between them.

A Systematic Review on the Mental Health Status of Patients Infected With Monkeypox Virus

  • Anila Jaleel;Ghulam Farid;Haleema Irfan;Khalid Mahmood;Saeeda Baig
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.35 no.2
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    • pp.107-118
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    • 2024
  • Objectives: This study aims to extract and summarize the literature on the mental health status of patients with monkeypox. Methods: This review was carried out according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines using different databases and publishers such as Scopus, Sage, ScienceDirect, PubMed, BMJ, Wiley Online Library, Wolters Kluwer OVID-SP, and Google Scholar. The literature review was based on monkeypox and mental health. The year of publication was 2021-2023, during the monkeypox disease period. Data were extracted from opinions, editorials, empirical studies, and surveys. Results: Based on the literature related to the mental status of patients with monkeypox, the following themes and subthemes were identified: anxiety and depression, self-harm and suicidal tendencies, neuropsychiatric symptoms, mental health, social stigma, sex workers, vaccination, and stress-related diseases. Conclusion: A review of monkeypox virus infection studies reveals that 25%-50% of patients experience anxiety and depression due to isolation, boredom, and loneliness. Factors such as infected people, a lack of competence among healthcare professionals, and shame over physical symptoms exacerbate mental insults. The implications of society include increased self-harm, suicide, low productivity, fear of stigmatization, and transmission of infection.

The Change in Modeling Ability of Science-Gifted Students through the Co-construction of Scientific Model (과학적 모델의 사회적 구성 수업을 통한 과학 영재 학생들의 모델링 능력 변화)

  • Park, Hee-Kyung;Choi, Jong-Rim;Kim, Chan-Jong;Kim, Heui-Baik;Yoo, Junehee;Jang, Shinho;Choe, Seung-Urn
    • Journal of The Korean Association For Science Education
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    • v.36 no.1
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    • pp.15-28
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    • 2016
  • The purpose of this study is to investigate the changes of students' modeling ability in terms of 'meta-modeling knowledge' and 'modeling practice' through co-construction of scientific model. Co-construction of scientific model instructions about astronomy were given to 41 middle-school students. The students were given a before and after instruction modeling ability tests. The results show that students' 'meta-modeling knowledge' has changed into a more scientifically advanced thinking about models and modeling after the instruction. Students were able to be aware that 'they could express their thoughts using models', 'many models could be used to explain a single phenomena' and 'scientific models may change' through co-construction modeling process. The change in the 'modeling practice' of the students was divided into four cases (the level improving, the level lowering, the high-level maintaining, the low-level maintaining) depending on the change of pre-posttest levels. The modeling practice level of most students has improved through the instruction. These changes were influenced by co-construction process that provides opportunities to compete and compare their models to other models. Meanwhile, the modeling practice level of few students has lowered or maintained low level. Science score of these students at school was relatively high and they thought that the goal of learning is to get a higher score in exams by finding the correct answer. This means that students who were kept well under traditional instruction may feel harder to adapt to co-construction of scientific model instruction, which focuses more on the process of constructing knowledge based on evidences.

Evaluation of Chloride and Chemical Resistance of High Performance Mortar Mixed with Mineral Admixture (광물성 혼화재료를 혼입한 고성능 모르타르의 염해 및 화학저항성 평가)

  • Lee, Kyeo-Re;Han, Seung-Yeon;Choi, Sung-Yong;Yun, Kyong-Ku
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.5
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    • pp.618-625
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    • 2018
  • With the passing of time, exposed concrete structures are affected by a range of environmental, chemical, and physical factors. These factors seep into the concrete and have a deleterious influence compared to the initial performance. The importance of identifying and preventing further performance degradation due to the occurrence of deterioration has been greatly emphasized. In recent years, evaluations of the target life have attracted increasing interest. During the freezing-melting effect, a part of the concrete undergoes swelling and shrinking repeatedly. At these times, chloride ions present in seawater penetrate into the concrete, and accelerate the deterioration due to the corrosion of reinforced bars in the concrete structures. For that reason, concrete structures located onshore with a freezing-melting effect are more prone to this type of deterioration than inland structures. The aim of this study was to develop a high performance mortar mixed with a mineral admixture for the durability properties of concrete structures near sea water. In addition, experimental studies were carried out on the strength and durability of mortar. The mixing ratio of the silica fume and meta kaolin was 3, 7 and 10 %, respectively. Furthermore, the ultra-fine fly ash was mixed at 5, 10, 15, and 20%. The mortar specimens prepared by mixing the admixtures were subjected to a static strength test on the 1st and 28th days of age and degradation acceleration tests, such as the chloride ion penetration resistance test, sulfuric acid resistance test, and salt resistant test, were carried out at 28 days of age. The chloride diffusion coefficient was calculated from a series of rapid chloride penetration tests, and used to estimate the life time against corrosion due to chloride ion penetration according to the KCI, ACI, and FIB codes. The life time of mortar with 10% meta kaolin was the longest with a service life of approximately 470 years according to the KCI code.

Structure activity relationship on the herbicidal activity by the N-phenyl substituents of 2-(4-(6-chloro-2-benzoxazolyloxy)phenoxy)-N-Phenylpropionamide derivatives in down land (수답에서 2-(4-(6-chloro-2-benz-oxazolyloxy)phenoxy)-N-phenylpropionamide 유도체 중 N-phenyl 치환체들의 제초활성)

  • Sung, Nack-Do;Lee, Sang-Ho;Ko, Young-Kwan;Lee, Kyung-Mo;Kim, Dae-Whang;Kim, Tae-Joon
    • The Korean Journal of Pesticide Science
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    • v.4 no.2
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    • pp.21-28
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    • 2000
  • A new fourty six 2-(4-(6-chloro-2-benzoxazolyloxy)phenoxy)-N-phenylpro- pionamide derivatives were synthesized and the herbicidal activities against rice plant and barnyard grass with pre-emergence in down land were measured. The structure activity relationships (SAR) between the activities and physicochemical parameters of the substituted(X) N-phenyl group in substrates were analyzed and discussed by Free- Wilson and Hansch method from the basis on the former study (Sung. et. al., 1999). The conditions of selective herbicide activity both the barnyard grass and rice plant are shown that the optimal hydrophobicity, $({\pi})_{opt.}=1.34$ and electron donating with field effect (F<0) of meta and ortho, para-substituted mono or disubstituent on the N-phenyl ring were found to contribute significantly. The herbicidal activities against barnyard grass are roughly the same as the results in up land whereas damage to rice plant in down land more increase than that of up land. Degradation products in water are 2-(4-(6-chloro-2-benzoxazolyloxy)phenoxy)propionic acid ((A)) (obs. pKa=4.35 & obs. logP=4.77) and 6-chloro-2-benzoxazolone (B) (obs. pKa=8.40 & obs. logP=2.90). These results were supposing that the hydrolysis product of substrates, (A) is comparatively absorbed in rice plant but not in barnyard grass. And it is assumed from the SAR equations that the 2,6-dimethyl-4-methoxymethyl group substituent ($pI_{50}=5.41$, 3g/ha) is selected as the most highest herbicidal activity against barnyard grass in green house.

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Efficacy and Safety of COVID-19 Vaccines in Adolescents: Systematic Review of Randomized Controlled Studies and Observational Studies

  • Soo-Han Choi;Su-Yeon Yu;Jimin Kim;Miyoung Choi;Youn Young Choi;Jae Hong Choi;Ki Wook Yun;Young June Choe
    • Pediatric Infection and Vaccine
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    • v.31 no.1
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    • pp.12-24
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    • 2024
  • The number of pediatric coronavirus disease 2019 (COVID-19) cases worldwide are increasing compared to the early phase of the pandemic, along with highly transmissible severe acute respiratory syndrome coronavirus variant and the increase in adult COVID-19 vaccination. We conducted a rapid systematic review and meta-analysis of published randomized clinical trials (RCTs) of the COVID-19 vaccines and the observational retrospective studies on adverse events after COVID-19 vaccination in adolescents. Seventeen studies were finally included in this systematic review. Meta-analysis showed that although vaccination in adolescents was significantly effective to prevent COVID-19 infection in retrospective studies (risk ratio [RR], 0.29; 95% confidence interval [CI], 0.22-0.37; I2 =100%), however the effect of preventing COVID-19 infection was lower than in RCTs (RR, 0.05; 95% CI, 0.01-0.27). In five retrospective studies, the pooled estimated proportion of participants with myocarditis and/or pericarditis was 2.33 per 100,000 of the population (95% CI, 0.97-5.61 per 100,000). Sub-group analysis with sex and vaccine doses showed that male (5.35 per 100,000) and the second dose (9.71 per 100,000) had significantly higher incidence of myocarditis and/or pericarditis than female (1.09 per 100,000) and the first dose (1.61 per 100,000), respectively. Our study showed that mRNA COVID-19 vaccines in adolescent recipients were favorable and effective against COVID-19 in RCT as well as observational studies. The safety findings of BNT162b2 vaccine in adolescents were explored and we found the difference of safety according to sex and vaccine doses. The occurrence of adverse events after mRNA COVID-19 vaccination should be monitored.

Qualitative Meta-analysis on Students' Understanding of Earth Science Concepts from the Perspective of Collective PCK: Focusing on the Concepts of Greenhouse Effect, Global Warming, and Climate Change (집단적 PCK 관점에서 학생들의 지구과학 개념 이해에 대한 질적 메타 분석: 온실 효과, 지구 온난화, 기후변화 개념을 중심으로)

  • Kwon Jung Kim;Eui Seon Choi;Ho Jun Kim;Jae Yong Park;Ki Young Lee
    • Journal of the Korean earth science society
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    • v.45 no.3
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    • pp.239-259
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    • 2024
  • In this study, a qualitative meta-analysis was conducted on research papers on earth science education to derive knowledge of students' understanding of specific science topics-greenhouse effect, global warming, and climate change-within the context of collective Pedagogical Content Knowledge (PCK). Twenty-two research papers addressing students' alternative conceptions (misconceptions) about these topics were selected and analyzed for their respective definitions, causes (mechanisms), and impacts. Semantic network analysis and a mental model framework were applied to synthesize the findings. The meta-analysis revealed several key insights: (1) Regarding the greenhouse effect, students often used the terms "greenhouse effect" and "global warming" interchangeably, lacked knowledge about the types of greenhouse gases, and misunderstood their roles. They commonly associated the greenhouse effect with environmental pollution or changes in the ozone layer, failing to recognize its relation to the heat balance between the surface and atmosphere. (2) Concerning global warming, students confused it with sea level rise and linked it to pollution, ozone layer changes, and glacier melting. They understood global warming as a disruption of the heat balance between the surface and atmosphere but had misconceptions about its environmental impacts. (3) In terms of climate change, students used the term interchangeably with global warming, weather change, and climate anomalies. They associated climate change with atmospheric pollution and ozone layer depletion but misunderstood its environmental impacts. As result, three mental models-categorical, mechanistic, and hierarchical misconceptions-were identified as collective PCK. The implications for enhancing earth science teachers' PCK were discussed based on these findings.