• 당뇨병
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• 제16권3호
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• pp.161-167
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• 2015

In Korea, diabetes mellitus, which causes micro and macrovascular complications, has been rapidly increasing during recent decades and has become a leading cause of disability-adjusted life years. The prevalence of diabetes mellitus was 12.4% in 2011 and that of prediabetes, a condition of high risk for developing diabetes mellitus, is 1.5- to 3-fold greater than that of diabetes. The diabetes prevention programs in other countries were shown to reduce or delay progression from prediabetes to diabetes mellitus. However, these results are not applicable to Korean people because of genetic and environmental differences. Therefore, we need to plan and perform a diabetes prevention study in Korean. Based on these results, we should design intervention tools for a Korean diabetes prevention program. We can consider several preventive interventions with lifestyle modification suitable for Korean people and pharmacologic treatments such as metformin or alpha-glucosidase inhibitor.

• 지역사회간호학회지
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• 제26권2호
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• pp.150-159
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• 2015

Purpose: This study was performed in order to identify the relationships among self-care behavior, health conservation, and cardiovascular risk factors and to examine the influence of self-care behavior and health conservation on cardiovascular risk factors among Korean elders with diabetes mellitus. Methods: The participants were 105 elders with diabetes mellitus using senior welfare centers and elderly leisure houses in Daegu. Data were collected through interviews during the period from April to May in 2014. Self-care behavior was measured with Kim's (1997) Self-care Behavior Scale, health conservation with Sung's (2005) Health Conservation Scale, and cardiovascular risk factors with the Arizona Heart Institute Cardiovascular Risk Factor Questionnaire. Collected data were analyzed through one-way ANOVA, independent t-test, Pearson's correlation, and stepwise multiple regression using the SPSS/WIN 19.0 program. Results: A negative correlation was found between self-care behavior and cardiovascular risk factors, and between health conservation and cardiovascular risk factors. Self-care behavior explained 6% and health conservation did 49% of variance in elderly diabetes mellitus patients' cardiovascular risk. Conclusion: The results indicate that, in order to reduce cardiovascular risk factors among Korean elders with diabetes mellitus, we need nursing interventions for increasing health conservation and self-care behavior.

• 기본간호학회지
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• 제23권4호
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• pp.393-401
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• 2016

Purpose: The purpose of this study was to examine the relationships among sexual function, sexual stress, and quality of life in middle aged women patients with diabetes mellitus. Methods: Data were collected through questionnaires distributed to 154 middle aged women patient with diabetes mellitus in one hospital. Results: The mean sexual function score was $12.99{\pm}9.11$. There were statistically significant differences in sexual function according to age, level of education, employment status, time of being diagnosed with diabetes mellitus, number of complications, self-monitoring of blood glucose, menopausal status, and level of glycosylated hemoglobin. The mean sexual stress score was $26.99{\pm}16.88$. The score of quality of life was $79.12{\pm}14.30$. There were statistically significant differences in quality of life according to level of education. Sexual function was negatively correlated with sexual stress (r=-.46 p<.001) and positively correlated with quality of life (r=.32, p<.001), while sexual stress was negatively correlated with quality of life (r=-.36 p<.001). Conclusion: Higher sexual dysfunction in middle aged women patients with diabetes mellitus was correlated with lower sexual stress and improved quality of life, while lower sexual stress was correlated with improved quality of life.

• 한국보건간호학회지
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• 제34권1호
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• pp.35-47
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• 2020

Objectives: This study investigated the effect of physical activity of adult Korean males on the prevalence of diabetes mellitus. Methods: This cross-sectional study used the raw data from the 2017 Community Health Survey. The subjects of this study were 74,494 men aged 19-64 years old. The data was analyzed applying the complex sampling design and using SPSS 23.0 Program. Descriptive statistics, Rao-Scott Chi-square tests and multiple logistic regression analysis were all performed. Results: The prevalence of diabetes mellitus was 6.4%. The walking activity was 58.5% and the over moderate intensity physical activity was 27.5%. After adjusting for age, marital status, educational level, household monthly income, drinking and smoking status, and BMI, those subjects without moderate intensity physical activity had a 1.14 times higher prevalence of diabetes mellitus (95% CI = 1.05-1.24) than those men with moderate intensity physical activity. Conclusion: In order to decrease the prevalence of diabetes mellitus among adult men, regular physical activities over a moderate intensity level should be emphasized and encouraged in daily life.

• Journal of Korean Dental Science
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• 제8권2호
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• pp.89-94
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• 2015

As popularity of dental implantation is increasing, the number of cases associated with complications also increase. Evaluation on diabetes mellitus is often neglected due to the disease's irrelevance to implantability. However, patients with diabetes mellitus are susceptible to infection due to impaired bactericidal ability of neutrophils, cellular immunity and activity of complements. Due to this established connection between diabetes mellitus and infection, a couple of cases were selected to present patients with diabetes mellitus with glycemic incontrollability, suffering from post-implantation dentigerous inter-fascial space abscess.

• 대한임상검사과학회지
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• 제45권1호
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• pp.9-15
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• 2013

Hepatitis B virus (HBV) infection has recently shown to be associated with diabetes mellitus. The objective of this study was to investigate the relationship between chronic hepatitis B and diabetes mellitus indicators. We evaluated anthropometry, metabolic syndrome risk factors, fasting glucose, HbA1c, and C-peptide among the normal and HBV subjects. The partial correlation and average comparison analysis were used to assess the independent association between chronic hepatitis B and diabetes mellitus indicators. Average comparisons of normal and HBV subjects were significantly different in fasting glucose (p<0.000), HbA1c (p<0.000), C-peptide (p<0.000), alanine transaminase (ALT) (p<0.000) and aspartate transaminase (AST) (p<0.000). We may suggest that HBV infection is related to diabetes mellitus indicators such as fasting glucose, HbA1c and C-peptide.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제19권3호
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• pp.311-318
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• 1997

Ludwig's angina has been defined as a potentially lethal, rapidly spreading cellulitis, involving the sublingual and submandibular spaces, and is manifesed by a brawny, suprahyoid induration, tender swelling in the floor of mouth, elevation and posterior displacement of tongue. This paper is of interest not only because of severity of infection but also because of associated diabetic mellitus. Diabetes mellitus is a complex syndrome of disordered metabolism and elevated blood glucose, it results from deficiency of insulin secretion of combination of insulin resistance and inadequate insulin secretion. The effects of diabetic mellitus include neuropathy, vascular insufficiency, decreased leukocytic function, hematologic change etc. Clinically this may be refelected by the increased severity of infections seen in diabetics. The treatment of infections in diabetics are reduction of number of microbes through the use of appropriated antimicrobial agents and proper surgical drainage and improvement of the host factors by tight control of insulin replacement and immediate intervention to correct abnormalities of the local factors by drainage, debriment, and removal of avoidance of foreign bodies. The authors present the report of the Ludwig's angina in patient with diabetic mellitus, with literature review and good clinical result.

• BMB Reports
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• 제37권2호
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• pp.234-238
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• 2004

This study was designed to investigate, in the Turkish population, the association of methylene tetrahydrofolate reductase (MTHFR) C677T polymorphism and left ventricular hypertrophy (LVH) in patients with type II diabetes mellitus. Our study included 249 patients with type II diabetes mellitus (102 men, 147 women) and 214 healthy volunteers as controls (91 men, 123 women). MTHFR C677T genotypes were determined by polymerase chain reaction, restriction fragment length polymorphism techniques. No differences were observed in the distribution of MTHFR genotypes or allele frequencies in the cases versus the controls. The frequency of the MTHFR-mutated allele (T) was 31.7% in the type II diabetes mellitus versus 31.1% of the controls. The homozygous mutation (T/T) in the MTHFR gene was identified in 12% of the type II diabetes mellitus versus 9.3% of the controls. Patients with the TT genotype showed a higher prevalence of LVH when compared to patients with the CC and CT genotypes (p = 0.01). The MTHFR gene C677T mutation may be a possible risk factor for the development of LVH in the type II diabetic patients.

• Archives of Pharmacal Research
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• 제26권6호
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• pp.499-503
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• 2003

Because physiological changes that potentially alter pharmacokinetics occurs in diabetes mellitus patients, pharamacokinetics of drugs used in the treatment of hypertension was studied using acebutolol as a model anti-hypertensive drug. Thus, the pharmacokinetics of acebutolol was investigated after oral administration of acebutolol (15 mg/kg) to control rabbits and rabbits with acute or chronic diabetes mellitus induced by alloxan. Kidney and liver functions were documented for acute and chronic diabetes mellitus groups based on plasma chemistry data. After oral administration of acebutolol to acute and chronic groups, the plasma concentrations appeared higher; As a result, area under the plasma concentration-time curve from time zero to time infinity10575 and 8668 $\mu g\cdot$ h/mL for acute and chronic group, respectively. In comparison, the area was apparently smaller in the control group (i.e., 7132 $\mu g\cdot$ h/mL). The half-life in acute groups was significantly prolonged 8.45 h compared with the half-life in the control group (i.e., 6.30 h). Alteration in acebutolol pharmacokinetics was more pronounced in the acute group as evidenced by the significantly higher values the area under the plasma concentration time curve, absorption rate constant and maximum plasma concentration compared with chronic or control group. Therefore, these observations indicate that acebutolol pharmacokinetics may be affected in patients with diabetes mellitus, especially in the early stage of the disease.

• 가정간호학회지
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• 제24권2호
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• pp.160-168
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• 2017

Purpose: Optimism is an important psychological variable that functions positively in stress adaptation process. The purpose of this study was to identify either a mediating or moderating effect of optimism in the relationship between stress and well-being among mothers of children with diabetes mellitus. Methods: A sample of 109 mothers of children with diabetes mellitus was recruited in a tertiary hospital in B city and they completed self-reported questionnaires. Multiple regression analysis models were used to test the mediating and moderating effects of optimism in the relationship between stress and well-being. Results: The results of the multiple and hierarchical regression analysis showed that the role of optimism was examined a partial mediator of the relation between stress and well-being, not a moderator. Increased stress was associated with decreasing optimism and well-being, and increased optimism predicted increased well-being among mothers of children with diabetes mellitus. Conclusion: Optimism is more likely to play a role as mediator, rather than as a moderator. This finding suggests the importance of optimism in improving the well-being of mothers of children with diabetes mellitus.