Korean Journal of Clinical Laboratory Science (대한임상검사과학회지)

Korean Society for Clinical Laboratory Science (대한임상검사과학회)
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Correlation of Chronic Hepatitis B Virus Infection with Diabetes Mellitus Indicators

  • Lee, Jung Hwa (Department of Biomedical Laboratory Science, Eulji University School of Medicine) ;
  • Hyun, Sung Hee (Department of Biomedical Laboratory Science, Eulji University School of Medicine) ;
  • Park, Kap Tae (Department of Biomedical Laboratory Science, Eulji University School of Medicine) ;
  • Ahn, Tae Ho (Department of Biomedical Laboratory Science, Eulji University School of Medicine) ;
  • Kim, In Sik (Department of Biomedical Laboratory Science, Eulji University School of Medicine)
  • Received : 2012.11.12
  • Accepted : 2013.03.13
  • Published : 2013.03.30
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Abstract

Hepatitis B virus (HBV) infection has recently shown to be associated with diabetes mellitus. The objective of this study was to investigate the relationship between chronic hepatitis B and diabetes mellitus indicators. We evaluated anthropometry, metabolic syndrome risk factors, fasting glucose, HbA1c, and C-peptide among the normal and HBV subjects. The partial correlation and average comparison analysis were used to assess the independent association between chronic hepatitis B and diabetes mellitus indicators. Average comparisons of normal and HBV subjects were significantly different in fasting glucose (p<0.000), HbA1c (p<0.000), C-peptide (p<0.000), alanine transaminase (ALT) (p<0.000) and aspartate transaminase (AST) (p<0.000). We may suggest that HBV infection is related to diabetes mellitus indicators such as fasting glucose, HbA1c and C-peptide.

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