• The Journal of the Korea Contents Association
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• v.18 no.4
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• pp.480-494
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• 2018

The purpose of this study is to develop a nursing activity cost calculation program based on Lee's doctoral dissertation using TD-ABC. The developed program has been supplemented with data storage, print out, and graph conversion functions to expand the application possibility. The development of the program consisted of three steps: program requirements analysis, program design and development, and program validation. This program was designed not only to do the cost calculation, but also to compare the cost-effectiveness and cost consumption trends. Consequently, this program is meaningful in that the nursing manager can obtain the cost information necessary for nursing unit management and extend the utilization so that the cost management strategy can be established based on the cost information. Therefore, we propose that the cost-management capacity of clinical nurses should be strengthened and the nursing performance measurement research should be expanded by applying it to various actual clinical nursing management settings. It is suggested that this program should be used as a training medium to strengthen nurse cost management capacity by combining nursing management curriculum at undergraduate level.

• Journal of the Institute of Electronics and Information Engineers
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• v.53 no.12
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• pp.67-75
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• 2016

DNA computing technology makes the interests on DNA storage and DNA watermarking / steganography that use the DNA information as a newly medium. DNA watermarking that embeds the external watermark into DNA information without the biological mutation needs the reversibility for the perfect recovery of host DNA, the continuous embedding and detecting processing, and the mutation analysis by the watermark. In this paper, we propose a reversible DNA watermarking based on circular histogram shifting of DNA code values with the prevention of false start codon, the preservation of DNA sequence length, and the high watermark capacity, and the blind detection. Our method has the following features. The first is to encode nucleotide bases of 4-character variable to integer code values by code order. It makes the signal processing of DNA sequence easy. The second is to embed the multiple bits of watermark into -order coded value by using circular histogram shifting. The third is to check the possibility of false start codon in the inter or intra code values. Experimental results verified the our method has higher watermark capacity 0.11~0.50 bpn than conventional methods and also the false start codon has not happened in our method.

• Clinical and Experimental Reproductive Medicine
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• v.29 no.2
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• pp.105-115
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• 2002

Objective : To evaluate the effects of the reactive oxygen species (ROS) generated with a xanthine (X) and xanthine oxidase (XO) system on sperm function, the change of sperm characteristics, lipid peroxidation, and DNA fragmentation in bovine spermatozoa. Materials and Methods: ROS were produced using a combination of 1000 uM X and 50 mU/ml XO. The ROS scavengers: superoxide dismu tase (SOD) (200 U/ml) and catalase (500 U/ml) were also tested. Spermatozoa were incubated for 2 hours in BWW medium with a combination of X-XO supplemented with or without ROS scavengers at $37^{circ}C$ under 5% $CO_2$ incubator. Sperm movement characteristics by CASA (computer-aided sperm analysis), HOST (hypoosmotic swelling test), Caionophore induced acrosome reaction, malondialdehyde formation for the analysis of lipid peroxidation, the percentage of DNA fragmentation using the method of TdT-mediated nick end labelling (TUNEL) by flow cytometry were determined after 2 hours incubation. Results: The action of ROS on bovine spermatozoa resulted in a decreased in capacity for sperm motility, Ca-ionophore induced acrosome reaction and membrane integrity, an increased in malondialdehyde formation and the percentage of sperm with DNA fragmentation. In the effects of antioxidant, catalase completely alleviated the toxic effects induced by the ROS in terms of sperm function and characteristics, however SOD exhibited no capacity to reduce the toxic effects. Conclusion: The ROS can induce significant damages to sperm functions and characteristics. The useful ROS scavengers can minimized the defects of sperm function and various damages of spermatozoa.

• Journal of Korean Society of Steel Construction
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• v.27 no.5
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• pp.423-433
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• 2015

A double split tee connection, which is a beam-column moment connection, shows different behavioral characteristics under the influences of the thickness of a T-stub flange, a high-strength bolt gauge distance, and the number and diameter of a high-strength bolt. A double split tee connection is idealized and designed that a flexural moment normally acting on connections can be resisted by a T-stub and a shear force by a shear tap. However, where a double split tee connection is adopted to a low-and medium-rise steel structure, a small-sized beam member can be adopted. Then, a shear tab may not be bolted to the web of a beam. This study was conducted to suggest the details of a connection to secure that a double split tee connection with a geometric shape has a sufficient capacity to resist a shear force. To verify this, this study was conducted to make a three-dimensional nonlinear finite element analysis on a double split tee connection.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.15 no.5
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• pp.145-155
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• 2020

In this study, the purpose of the study is to derive the relationship between factors affecting the establishment of start-up companies, technical innovation performance, and technology commercialization, and to confirm the effects of start-up factors and technology commercialization on the technological innovation performance based on the analysis. For this research, a survey was conducted on employees aged 20 or older who were employed in large national enterprises or medium and small-sized enterprises, etc. and the results of the empirical analysis were as follows. Firstly, the factors influencing start-ups were found to have a significant impact on the technology commercialization(manufacturing capacity, producing capacity). Secondly, technology commercialization had a significant impact on the technological innovation performance(business performance, customer performance), and thirdly, technology commercialization had a partial mediating effect in the relationship between start-up factors and technical performance. This study confirmed that the factors of start-up, technology commercialization, and technological innovation performance have statistically significant impact relations, and further research on start-up factors and technology commercialization is necessary for the technological innovation and creation of companies.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.20 no.6
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• pp.561-567
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• 1987

The purpose of this study was to find out the removal capacity of harmful ammonia by different filter media in the submerged biological filters in a given space of chamber. Four materials, pile cloth, corrugated skylight roofing plate, embossed plastic plate, and gravel, were used as the experimental filter media. Each filter medium was placed in two aquariums, each aquarium measuring $90cm\times60cm\times60cm\;(depth)$. Under the normal operating condition, the average of mean ammonia removal rates during the first and second functioning periods by each filter material which occupied tile space in the filter chamber (aquarium) was as follows: 1. Pile cloth: $8.381\;g{\cdot}m^{-3}.\;day^{-1}$ 2. Corrugated skylight roofing plate: $7.834\;g{\cdot}m^{-3}.\;day^{-1}$ 3. Embossed plastic plate: $7.797\;g{\cdot}m^{-3}.\;day^{-1}$ 4. Gravel: $7.051\;g{\cdot}m^{-3}.\;day^{-1}$ Thus, there were no significant differences between the media, but at the time of practical application of these materials, some other factors such as investment cost, easiness for the removal of excess detritus accumulated in tile interstices of filter media, etc. should be fallen into consideration. When large units are required, in particular, removal of excess detritus from tile gravel bed is extremely difficult, and in case of pile cloth filters the installation work is much complicated and a problem in supporting the structure when drained also exists. In these respects, corrugated skylight roofing plate and embossed plastic plate seem to be more optimal, but again in practice the local situation for the availability and the price of the materials should be rechecked and the fitness of tile materials in the particular filter chambers under use or under consideration for construction must be taken into account.

• Tuberculosis and Respiratory Diseases
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• v.69 no.6
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• pp.456-464
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• 2010

Background: Synergistic antitumor effects of the combined chemoimmunotherapy based on dendritic cells have been reported recently. The aim of this study is to search new applicability of gefitinib into the combination treatment through the confirmation of gefitinib effects on the monocyte derived dendritic cells (moDCs); most potent antigen presenting cell (APC). Methods: Immature and mature monocyte-derived dendritic cell (im, mMoDC)s were generated from peripheral blood monocyte (PBMC) in Opti-MEM culture medium supplemented with IL-4, GM-CSF and cocktail, consisting of TNF-${\alpha}$ (10 ng/mL), IL-$1{\beta}$ (10 ng/mL), IL-6 (1,000 U/mL) and $PGE_2$ ($1{\mu}/mL$). Various concentrations of gefitinib also added on day 6 to see the influence on immature and mature MoDCs. Immunophenotyping of DCs under the gefitinib was performed by using monoclonal antibodies (CD14, CD80, CD83, CD86, HLA-ABC, HLA-DR). Supernatant IL-12 production and apoptosis of DCs was evaluated. And MLR assay with $[^3H]$-thymidine uptake assay was done. Results: Expression of CD83, MHC I were decreased in mMoDCs and MHC I was decreased in imMoDCs under gefitinib. IL-12 production from mMoDCs was decreased under $10{\mu}M$ of gefitinib sinificantly. Differences of T cell proliferation capacity were not observed in each concentration of geftinib. Conclusion: In spite of decreased expressions of some dendritic cell surface molecules and IL-12 production under $10{\mu}M$ of gefitinib, significant negative influences of gefitinib in antigen presenting capacity and T cell stimulation were not observed.

• Journal of Korean Society of Steel Construction
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• v.17 no.4 s.77
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• pp.419-429
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• 2005

The objective of this study is to clarify the structural features of members consisting of a connection, as part of the previous study on the CFT column-to-beam tensile connection with a combined cross diaphragm. This connection has the following merits: it evenly distributes the stress on the beam flange and the diaphragm and reduces the stress concentration by improving the stress transfer route and restraining the abrupt deformation of the diaphragm. Finite element analysis was performed to find out the stress transfer through the sleeve, which is an important member of the connection with a combined cross diaphragm. The length and thickness of the sleeve were used as variables for the analysis. The analysis results showed that the length and thickness of the sleeve did not influence the capacity of the connection and played the role of a medium for the transfer of the stress from the diaphragm to the filled concrete. It was proposed that the appropriate length of the sleeve have the same value as the diameter of the sleeve and that the appropriate ratio of the sleeve diameter to the sleeve thickness be 20. Two equations for the evaluation of the load carrying the capacity of the connection were also proposed through the modification of the evaluation equation suggested in the previous study.

• Journal of Animal Environmental Science
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• v.18 no.2
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• pp.63-74
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• 2012

This experiment was carried out to investigate the effect of different stocking rate on growth, cast production and conversion efficiency of organic matter to tissues of earthworm. The carbon and nitrogen ratio (C/N) of tested Korean cow manure was 25.1, it was estimated an adequate ratio as feed for earthworms. The different stocking rates were 1:8(S-1), 1:16(S-2), 1:32(S-3) 1:64(S-4) 1:128(S-5) and 1:256 (S-6) as the ratios of earthworm fresh weight to biomass of Korean cow manure, respectively. A stocking rate of 1:32(S-3) was obtained a significantly highest values of increasing rate and conversion efficiency of organic matter to earthworm tissues. The mean values of increasin g rate of fresh weight and conversion efficiency of organic matter to earthworm tissues were 10.63 mg/day and 6.65% at the ratio of 1:32(S-3) with a rearing volume was $56.6cm^3$. A stocking rate of 1:8(S-1) was obtained a highest ratio of vermicasts, but showed a negative values of increasing rate and conversion efficiency of organic matter to earthworm tissues, it may due to severely food competition between individuals during the rearing periods. The pH, total nitrogen, available phosphorus, cation exchange capacity and exchangeable cations of vermicasts tended to increase with stocking rate. Especially, available phosphorus, cation exchange capacity and exchangeable cations of vermicasts tended to increase with rearing progressed. Vermicasts have the potential for improving plant growth when amended to container medium and soil according to increased availability of nutrients and improved physicochemical properties.

• Journal of the Korean Association of Geographic Information Studies
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• v.5 no.1
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• pp.27-37
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• 2002

The classification accuracy of land cover has been considered as one of the major issues to estimate pollution loads generated from diffuse landuse patterns in a watershed. This research aimed to assess the effects of the acquisition methods and sampling size of training reference data on the classification accuracy of land cover using an imagery acquired by optical sensor(OPS) on JERS-1. Two kinds of data acquisition methods were considered to prepare training data. The first was to assign a certain land cover type to a specific pixel based on the researchers subjective discriminating capacity about current land use and the second was attributed to an aerial photograph incorporated with digital maps with GIS. Three different sizes of samples, 0.3%, 0.5%, and 1.0% of all pixels, were applied to examine the consistency of the classified land cover with the training data of corresponding pixels. Maximum likelihood scheme was applied to classify the land use patterns of JERS-1 imagery. Classification run applying an aerial photograph achieved 18 % higher consistency with the training data than the run applying the researchers subjective discriminating capacity. Regarding the sample size, it was proposed that the size of training area should be selected at least over 1% of all of the pixels in the study area in order to obtain the accuracy with 95% for JERS-1 satellite imagery on a typical small-to-medium-size urbanized area.