• Advances in nano research
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• v.13 no.2
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• pp.121-134
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• 2022

Emerge of nanotechnology impacts all aspects of humans' life. One of important aspects of the nanotechnology and nanoparticles (NPs) is in the food production industry. The safety of such foods is not well recognized and producing safe foods using nanoparticles involves delicate experiments. In this study, we aim to incorporate intelligent computer simulation in predicting safety degree of nanofoods. In this regard, the safety concerns on the nano-foods are addressed considering cytotoxicity levels in metal oxides nanoparticles using adaptive neuro-fuzzy inference system (ANFIS) and response surface method (RSM). Three descriptors including chemical bond length, lattice energy and enthalpy of formation gaseous cation of 15 selected NPs are examined to find their influence on the cytotoxicity of NPs. The most effective descriptor is selected using RSM method and dependency of the toxicity of these NPs on the descriptors are presented in 2D and 3D graphs obtained using ANFIS technique. A comprehensive parameters study is conducted to observe effects of different descriptors on cytotoxicity of NPs. The results indicated that combinations of descriptors have the most effects on the cytotoxicity.

• Fisheries and Aquatic Sciences
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• v.25 no.10
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• pp.517-524
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• 2022

Over production of methylglyoxal (MGO) a highly reactive dicarbonyl compound, has been associated in progressive diabetes with vascular complication. Therefore, we investigated whether hot water extract of Loliolus beka meat (LBM-HWE) presents a preserve effect against MGO-induced cellular damage in human umbilical vein endothelial cells (HUVECs). The LBM-HWE extract showed to inhibit MGO-induced cytotoxicity. Additionally, the LBM-HWE reduced mRNA expression of pro-inflammatory cytokines, and reduced MGO-induced advanced glycation end product (AGEs) formation. Furthermore, LBM-HWE induced glyoxalase-1 mRNA expression and reduced MGO-induced carbonyl protein formation in HUVECs. The results implicate that LBM-HWE has protective ability against MGO-induced HUVECs toxicity by preventing AGEs formation. In conclusion, LBM-HWE could be used as a potential treatment material for the prevention of vascular complications of diabetes.

• Journal of Radiopharmaceuticals and Molecular Probes
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• v.6 no.2
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• pp.131-138
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• 2020

Fluorine compounds have attracted interest of scientists for immense applications in medicinal chemistry and pharmaceuticals. Recently, photoredox catalysts, both organic-based and metal-based compounds, have been employed in organic synthetic methodology to achieve desirable products due to facile operation and mild reaction condition. Various protocols to prepare fluorination adducts in the presence of photoredox catalysts have been developed from several starting materials with formation of radical scaffolds. In this review, we describe recent advances in the fluorination using light.

• The Ewha Medical Journal
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• v.40 no.3
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• pp.99-103
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• 2017

Antimicrobials were one of the great invention of modern era. However, the abuse of antimicrobial both in human and animals has led to a high rate of occurrence of antimicrobial resistant microbes. Disease treatment caused by antimicrobial resistant microbes including superbacteria has emerged as critical issue worldwide. Communication and cooperation among researchers in diverse fields are needed to solve the resistance to antimicrobials. Culture Collection of Antimicrobial Resistant Microbes (CCARM) has taken a leadership role an intermediary among various research fields by providing certified antimicrobial resistant microbes with their information since 1999. CCARM collects antimicrobial resistant microbes from clinical, agricultural animals and products, and environmental fields, and classifies and stores them according to their origins, species and antimicrobial resistance mechanisms. CCARM is performing the roles (collection, deposit, preservation, distribution, service, and consulting) of Biological Resource Center designated by Organisation for Economic Co-operation and Development.

• Journal of Marine Bioscience and Biotechnology
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• v.15 no.2
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• pp.90-95
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• 2023

This study aimed to develop low-salt seasoned Gim (김) with new functionality to meet the diversification of the export market and consumer demand for Gim, which is one of the four major seafood products in Chungcheongnam-do province. Spirulina, a microalgae containing essential amino acids, vitamins, and minerals, is known to have antioxidant components such as phycocyanin. Therefore, to determine the suitability of spirulina as a seasoning material, we conducted seaweed. It can be used as a substitute for seasoning salt in the development of low-salt seasoned laver with enhanced functionality.

• Journal of KIISE:Computing Practices and Letters
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• v.15 no.9
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• pp.661-674
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• 2009

Recently, there has been much research and many attempts to enhance converged information technology services using new technology such as ubiquitous sensor networks (USN) in medical, environmental, industrial, and logistic areas. There has also been much research and various attempts to apply this new technology to agricultural areas. However, applications to the agricultural areas should be considered differently against the same areas such as medical, environmental, industrial, and logistics. Therefore, this paper suggests that an agricultural cultivating management and traceability system. This system is a unified system that supports the processes sowing seeds through selling agricultural products to consumers. Farmers can be provided with an effective calendar for cultivation and weather information in real time as well as the monitoring of the growth of farm products on the farm in real time using this system. Farmers can also control all equipment installed on the farm directly or remotely and the equipment can be controlled automatically when the measured values such as temperature and humidity deviate from the decent criteria which are set by farmers or this system. Additionally, the reliability for and the better quality of the agricultural products can be improved because farmers can use this unified system to cover all processes from sowing seeds to selling to consumers.

• Journal of Radiation Protection and Research
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• v.47 no.4
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• pp.204-213
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• 2022

Background: The accident at the Fukushima Daiichi nuclear power plant increased the level of anxiety related to the radioactive contamination of various foods sourced in Japan. Particularly, after the accident, the detection of artificial radionuclides in locally produced foods raised food safety concerns. In this study, the radioactivity concentrations and annual ingestions of ⁴⁰K and ¹³⁷Cs in food products commonly and frequently consumed by the general public were investigated, and the annual effective dose of each was evaluated. Materials and Methods: The 2016-2018 data from the Radiation Safety Management Report released by the Korea Nuclear Safety Technology Center was referenced for the evaluation of the amounts of ⁴⁰K and ¹³⁷Cs contained in food. Using the food-ingestion survey mentioned above as a reference, we selected 62 foods to include in our radioactivity concentration and dose assessment. We also developed a questionnaire and evaluated the responses from the subjects who answered the questionnaire. Results and Discussion: The radioactivity concentration of ¹³⁷Cs was found to be close to or below the level of minimum detectable activity. Additionally, the annual ingestion of 62 foods was 294.77 kg/yr, the effective doses from ⁴⁰K and ¹³⁷Cs were 136.4 and 0.163 μSv/yr, respectively. Conclusion: Thus, the findings confirmed that the effective dose from ⁴⁰K and ¹³⁷Cs in food tends to be lower than the effective dose limit of 1 mSv/yr suggested by the International Commission on Radiological Protection (ICRP) Publication 60. The questionnaire developed in this study is expected to be useful for estimating the annual effective dose status of Korean adults who consume foods containing ⁴⁰K and ¹³⁷Cs.

• Natural Product Sciences
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• v.10 no.1
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• pp.32-34
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• 2004

Two 2-phenoxychromones; a rare group of natural products, were isolated from the combined ethylacetate and chloroform fractions of the ethanolic extract of Ononis serrata frossk (Leguminosae) growing in Egypt. Structures were elucidated by chemical, spectroscopic methods as well as single X-ray diffraction analyses. The cytotoxic and antimicrobial effects of the two compounds were examined. It is worth to mention that this is the first report on the isolation of 2-phenoxychromones from the family Leguminosae.

• Korean Journal of Microbiology
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• v.12 no.2
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• pp.67-76
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• 1974

This experiment was carried out to identify and to compare the radiosensitivities of bacteriz isolated from the sources of different radiation exposure histories. Among 10 strains isolated in this investigation, 4 strains of bacteria, Bacillus firmus, Bacillus brevis, Baciilus subtilis and Bacillus sphaericus were isolated from high and low radioactive sites simulaneously. Bacterial strains isolated from radioactive sources such as reactor and isotope production rooms were more resistant to irradiation than the microganisms from medical products and laboratories, however, there was no significance in radiosensitivity in the same species of bacteriz, even if they were isolated from different radiation exposure histories.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.22 no.52
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• pp.355-363
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• 1999

As the indirect cost is increasing, ABC(Activity-Based Costing) Method that can distribute the indirect cost to each products is more effectively used. Especially for a Hospital to provide better medical service with patients, It's necessary that build ABC System to provide a regular cost information. This study proposed methodology enabling accurate cost analysis from importing concepts of ABC in a Hospital and presented a Cost Information Table for Work-Time Table and Output Services to calculate ABC.