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Survival Rate of Breast Cancer in Iran: A Meta-Analysis

  • Abedi, Ghasem;Janbabai, Ghasem;Moosazadeh, Mahmood;Farshidi, Fereshte;Amiri, Mohammad;Khosravi, Ahmad
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.10
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    • pp.4615-4621
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    • 2016
  • Background: There has not been a general estimation about survival rates of breast cancer cases in Iran. Therefore, the present study aimed to assess survival using a meta-analysis. Materials and Methods: International credible databases such as Scopus, Web of Science, PubMed, Science direct and Google Scholar and Iranian databases such as Magiran, Irandoc and SID, from 1997 to 2015 were searched. All articles covering survival rate of breast cancer were entered into the study without any limits. Quality assessment of the articles and data extraction were performed by two researchers using the modified STROBE checklist, which includes 12 questions. Articles with scores greater than 8 were included in the analysis. A limitation of this meta-analysis was different methods for presenting of results in the papers surveyed. Results: A total of 21 articles with a sample of 12,195 people were analyzed. The one-year, three-year, five-year and ten-year survival rates of breast cancer in Iran were estimated to be 95.8% (94.6-97.0), 82.4% (79.0-85.8), 69.5% (64.5-74.5), 58.1% (39.6-76.6), respectively. The most important factors affecting survival of breast cancer were age, number of lymph nodes involved, size of the tumor and the stage of the disease. Conclusion: The five- and ten- year survival rates in Iran are lower than in developed countries. Conducting breast cancer screening plan support (including regular clinical examination, mammography), public training and raising awareness should be helpful in facilitating early diagnosis and increasing survival rates for Iranian women.

Research clinical trends on Gigong(氣功, Qigong) in the Korean Journal (한국(韓國) 저널에 게재(揭載)된 기공관련(氣功關聯) 임상(臨床) 연구(硏究) 동향(動向) 분석(分析) )

  • Han, Chang-Hyun;Lee, Sang-Nam;Kwon, Young-Kyu;Ahn, Sang-Woo;Choi, Sun-Mi
    • Journal of Korean Medical classics
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    • v.21 no.3
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    • pp.297-306
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    • 2008
  • Background : Gigong(氣功, Qigong) is one energy-healing intervention used to prevent and cure ailments and to improve health through regular practice. Although Gigong(氣功, Qigong) - neither itself nor its postulated mechanism of action - are within the paradigm of modern Western medical science, effects on the human body could be possible. Objectives : This study aims to review the bibliography, biological responses and therapeutic effects of Gigong. In the process, this review will grasp trends in this field of studies and will direct further researches into the right direction. Method : The computerized Korean databases were searched from their respective inceptions up to January 2008. The search terms used were 'Gi(氣, Qi)', 'Gigong(氣功, Qigong)', 'Doin(導引)', 'Training', 'Bioenergy', 'life nurturing' and random or Korean language terms related to Gigong. Several specialized journals were also manually searched for relevant articles. Result : Since the 1990's, Gigong papers in the Korean Literature is increased. Clinical research studies are among the most control design study. Research subjects are less patient than the general public. The most common treatment disease was Musculo-skeletal disorder Conclusions : The depth study for the each Gigong(氣功, Qigong) is needed. Specifically, I think it should be a clinical studies and qualitative research methods for evaluation are needed.

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Analysis of Research Trends on Postpartum-women Healthcare : A Scoping Review (스코핑 고찰 방법을 통한 산욕기 산모 건강관리에 대한 연구동향 분석)

  • Lee, Do-Eun;Park, Han-Song;Jin, Joon-Soo;Min, Beak-Ki;Youn, In-Ae;Suh, Hyo-Weon;Seo, Joo-Hee
    • The Journal of Korean Medicine
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    • v.41 no.3
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    • pp.32-54
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    • 2020
  • Objectives: The purpose of this scoping review is to describe the research trends of postpartum healthcare for postpartum women, as well as to identify further direction for research in the area of postpartum healthcare. Methods: This study was conducted sequentially according to the Scoping Review Method referred to as 'frameworks of Arskey and O'Malley'. We searched for articles published as of May 15th, 2020 in seven Korean databases in order to obtain the data. A key term search strategy was employed, including terms such as "Postpartum period care", "Postpartum health", "Postpartum care", and "Postpartum status" to identify relevant studies. Results: Eighty-three articles were selected from a total of 259. The research has been undertaken steadily since 1997, particularly in the fields of Nursing and Korean medicine. In terms of study design, survey studies were the majority (48.2%), followed by interventions and experimental papers (32.5%). However, qualitative research areas are lacking. The research topics were largely divided into two categories: postpartum care characteristics and postpartum care interventions. The characteristics of postpartum care were highly connected with care for mental health. Among the postpartum care interventions, the most common employed was Korean medicine intervention. Conclusion: This study confirms that management of mental health during the postpartum period is necessary. In addition, it is necessary to identify the experiences of postpartum women and the effectiveness of a postpartum care intervention program through the utilization of qualitative research methods. In particular, such research is needed in the field of Korean medicine.

Analysis of reports on orphan lung diseases in Korean children

  • Jang, Sun-Jung;Seo, Hyun-Kyung;Yi, Sung-Jae;Kim, Kyong-Min;Jee, Hye-Mi;Han, Man-Yong
    • Clinical and Experimental Pediatrics
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    • v.53 no.6
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    • pp.711-717
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    • 2010
  • Purpose: Orphan lung diseases are defined as lung diseases with a prevalence of 1 or less in 2,000 individuals. Despite an increase in the numbers of patients with such diseases, few studies on Korean children have appeared. To obtain epidemiologic and demographic data on these diseases, we systematically reviewed reports on pediatric orphan lung diseases in Korea over the last 50 years. Methods: We reviewed 223 articles that have appeared since 1958 on orphan lung diseases in Korean children. These articles described a total of 519 patients aged between 0 and 18 years. We classified patients by year of publication, diagnosis, geographic region, and journal. Results: Of 519 patients, 401 had congenital cystic lung diseases and 66 had bronchiolitis obliterans. About 80% of patients were described in reports published in three journals, Pediatric Allergy and Respiratory Disease (Korea), the Korean Journal of Pediatrics, and the Korean Journal of Thoracic and Cardiovascular Surgery, in which papers on 157 (30.2%), 138 (26.6%), and 111 (21.4%) patients appeared, respectively. The frequency of publication of case reports has increased since 1990. Of the 519 patients, 401 (77.3%) were from Seoul/Gyeonggi-do and 72 (13.9%) from Busan/Gyeongsangnam-do. Conclusion: The prevalence of pediatric orphan lung disease has increased since 1990, and some provinces of Korea have a higher incidence of these diseases than do others. Studies exploring the incidence of pediatric orphan lung diseases in Korea are needed for effective disease management.

Lack of Prognostic Value of Human Epidermal Growth Factor- Like Receptor 2 Status in Inflammatory Breast Cancer (IBC): a Meta-analysis

  • Li, Xiu-Juan;Zha, Quan-Bin;Xu, Xin-Yu;Xia, Lei;Zhang, Zhe;Ren, Zhao-Jun;Tang, Jin-Hai
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.22
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    • pp.9615-9619
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    • 2014
  • Inflammatory breast cancer (IBC) is a rare, aggressive form of breast cancer which is more likely to be her-2/neu amplified. While the her-2/neu status has been utilised to predict prognosis, the published data are inconsistent. The present meta-analysis was conducted to determine whether the her-2/neu status predicts outcomes. Papers were selected from the PubMed database based on defined inclusion and exclusion criteria. Parameters such as total patients, follow-up time and outcome statistics (i.e. overall survival (OS), relapse-free survival (RFS) were collected. The analysis included 6 studies with 2,838 IBC patients. The summary hazards ratio (HR) estimating the association of OS with HER-2-positive disease was 0.96 (95% confidence interval (95%CI: 0.85-1.10)), with similar findings for RFS (HR=0.81, 95%CI: 0.61-1.09). No obvious statistical heterogeneity was detected. This meta-analysis suggests that HER-2-positive status is not an independent adverse prognostic factor for survival among IBC patient cases.

The CCND1 G870A Gene Polymorphism and Brain Tumor Risk: a Meta-analysis

  • Qin, Ling-Yan;Zhao, Li-Gang;Chen, Xu;Li, Ping;Yang, Zheng;Mo, Wu-Ning
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.8
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    • pp.3607-3612
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    • 2014
  • Background: In recent years, numerous studies have been performed to investigate the CCND1 G870A gene polymorphism impact on brain tumors susceptibility. Unfortunately, the results of previous studies were inconsistent. Therefore, we performed a meta-analysis to derive a more precise estimation of any association. Materials and Methods: We conducted a search in PubMed, Embase and CNKI covering all published papers up to November, 2013. Odds ratios (ORs) and their 95% confidence intervals (95%CIs) were applied to assess associations. Results: A total of 6 publications including 9 case-control studies met the inclusion criteria. The pooled ORs for the total included studies showed significant association among comparison A vs G (OR= 1.246, 95%CI= 1.092-1.423, p= 0.001), homozygote comparison AA vs GG (OR= 1.566, 95%CI= 1.194-2.054, p= 0.001), heterozygote comparison AG vs GG (OR= 1.290, 95%CI= 0.934-1.782, p= 0.122), dominant model AA/GA vs GG (OR= 1.381, 95%CI= 1.048-1.821, p= 0.022) and recessive model AA vs GA/GG (OR= 1.323, 95%CI= 1.057-1.657, p= 0.015) especially in glioma. Conclusions: CCND1 G870A polymorphism may increase brain tumor risk, especially for gliomas. However, more primary large scale and well-designed studies are still required to evaluate the interaction of CCND1 G870A polymorphism with brain tumor risk.

The Dispute on the Modernization of Korean Medicine after the Restoration of Independence -Based on the 1950s and from the 1990s to the Present- (해방 이후 한의학의 현대화 논쟁 - 1950년대와 1990년대 이후의 논의를 바탕으로 -)

  • Lee, Tae-Hyung;Jung, Yoo-Ong;Lee, Duk-Ho;Kim, Nam-Il
    • Journal of Society of Preventive Korean Medicine
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    • v.16 no.3
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    • pp.53-73
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    • 2012
  • Objectives : The inclusion of Korean Medicine in the national health care system led to the need of a serious discussion on its modernization. This paper looked at how these discussions were progressed. Especially, a difference in the meaning of 'science' in the 1950s and the 1990s was observed. Methods : Articles related to the medical dispute between Korean and Western Medicine in "EE LIM", especially the ones from the 1950s, were selected, classified and analyzed. Research papers on Evidence-Based Medicine were also analyzed. Evidence-Based Medicine was a new medical research methodology in the 1990s. Articles on Evidence-Based Medicine were searched and selected from journal databases: DBpia, KISS, RISS, and OASIS. Results : The problem of establishment of modernity of Korean Medicine in the recent times was addressed in the context of scientification and systematization. Accordingly, the academic societies of Korean Medicine aimed for scientification. But efforts to secure the identity of Korean Medicine opposed to western science were also made. Meanwhile, Evidence-Based Medicine established in 1992 presented a different concept of science. This led to a new means of acknowledgement of Korean Medicine in the modern society. Conclusions : The modernization process of Korean Medicine up to now was a course of scientification. But as this process did not fully reflect its characteristics, the modernization of Korean Medicine still remains a pending question. A modern study methodology that fully reflects the identity of Korean Medicine needs to be established.

Trend Review of Traditional Chinese Medicine Studies on Pharmacopuncture Treatment for Post-Stroke Depression (뇌졸중 후 우울증의 약침치료에 대한 중의학 임상논문 연구동향)

  • Lee, Yeogyeong;Khang, Hyunjin;Song, Geumju;Oh, Jiyeon;Kim, Sangbeom;Kim, Jongmin;Park, Sejin
    • Journal of Oriental Neuropsychiatry
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    • v.32 no.3
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    • pp.235-245
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    • 2021
  • Objectives: To provide clinical evidence of pharmacopuncture treatment for post-stroke depression by reviewing randomized controlled trials on Traditional Chinese medicine pharmacopuncture for post-stroke depression. Methods: Randomized controlled trials on pharmacopuncture treatment for post-stroke depression were searched from the China National Knowledge Infrastructure (CNKI). Literature searches of English and Chinese databases were performed. Selected literature was assessed with the Jadad scale. Results: Twelve papers were selected from 20 studies. The following results were obtained: 1) Pharmacopuncture was used for post-stroke depression; 2) Dengzhan-Xixin was the most used injection medicine for post-stroke depression; 3) BaiHui (GV20) was the most used in pharmacopuncture treatment; 4) Based on the Hamilton Depression Rating Scale (HAMD), it was confirmed that all studies using pharmacopunture had significant efficacy. Conclusions: For the treatment of post-stroke depression, Dengzhans-Xixin was commonly used as an injectable medication. Additional research studies on pharmacopuncture including its practical use are needed.

Literature Review on Private Health Insurance for Korean older adults (한국 노인대상 민간의료보험에 관한 선행연구 고찰)

  • Choi, Hyoung-Shim
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.22 no.4
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    • pp.75-82
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    • 2021
  • The purpose of this study was to review literature about private health insurance (PHI) schemes for Korean older adults published in Korea and abroad from 2015 to 2019, and to present the implications of the study and provide an overview of PHI utilization by Korean older adults. Nineteen quantitative academic research papers were selected and analyzed with respect to presentation time, research purpose, data source, and study design. Old age, low income, low education, and chronic disease were found to hinder enrollment in PHI schemes. Although the relationship between PHI and medical usage was not consistent, it was positively related to health outcomes such as subjective health status and health-related quality of life. Therefore, for PHI to fulfill the role of providing supplementary medical care for older adults with high medical demands, a national improvement policy should be developed to address the barriers that prevent older adults adopting PHI schemes, and empirical studies related to medical usages by and the health outcomes of older adults should be conducted in order to generate a basis for the use of PHI.

The Latest Research Trend on Korean Medicine of Rib Fractures: Focused on China National Knowledge Infrastructure (CNKI), PubMed (늑골골절의 한의학적 치료에 대한 최신 연구동향: China National Knowledge Infrastructure (CNKI), PubMed를 중심으로)

  • Park, Eun Sang;Hwang, Hyeon Ho;Park, Ki Hyun;Kim, Ho Geol;Im, Ji Sung;Kang, Jun Hyuk
    • Journal of Korean Medicine Rehabilitation
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    • v.32 no.4
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    • pp.47-60
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    • 2022
  • Objectives The purpose of this study is to identify the latest research trends regarding the nonsurgical treatment of rib fractures and suggest the direction for future research. Methods We searched for papers published from January 1, 2015 to July 1, 2022 in PubMed and the China National Knowledge Infrastructure (CNKI) based on keywords 'rib fracture'. 'Korean medicine', 'oriental medicine', 'TCM', 'moxibustion', 'acupunture', 'cupping', 'electroacupuncture', 'pharmacopuncture', 'fire needling'. Results A total of 79 studies were searched at first research. Then the studies were screening according to criteria and Finally 20 studies were selected. The oriental medical interventions analyzed in this study were fumigation method, herbal medicine, external application, acupuncture, ointment, herb fomentation, Tending Diancibo Pu far-infrared therapy. Conclusions Various oriental medical interventions such as herbal medicine, acupuncture, fumigation, herb fomentation, ointment, and physical therapy are being studied abroad for the treatment of rib fractures. It is considered that additional research related to the nonsurgical treatment for rib fractures is needed in the future in korea.