• The Korea Journal of Herbology
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• v.30 no.5
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• pp.29-43
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• 2015

Objectives : This study was aimed to analyze the correlation between the Herbology and contemporary research results, KCD-codes.Methods : Papers were searched in OASIS and PubMed, then they were categorized. Medicine or pharmacy articles about Menthae Herba were matched with the Herbology treatment and KCD-codes. Other articles were analyzed by abstract of the papers. KCD-codes and terms were arranged by the Herbology treatment. The Degree of Herbology research (HDR) was calculated by numbers of papers, study method, citation rates.Results : There were 97 articles about Menthae Herba. Among these there were 47 medicine and pharmacy articles about Menthae Herba, and 15 articles were matched to the Herbology treatment. Studies about Headache and Wind-warmth was more active than others. Analysis of other articles showed that studies about contraceptive and anti-oxidative effect, plant growth, protective effect from insect, component extraction technics were active, too. In HDR, headache was scored by 136, Wind-warmth by 104, Eye hemorrhage by 51, Discomport in the throat by 50, Distention and fullness in the chest and hypochondrium by 15, Rubella and Measles by 0.Conclusions : 97 articles about Menthae Herba were analyzed and 15 articles were matched to the Herbology treatment. Studies about headache, wind-warmth, eye-hemorrhage were more active than others of the Herbology treatment. And studies about contraceptive and anti-oxidative effect, plant growth, protective effect from insect, component extraction technics could be a new subject of the Herbology.

• Korean Journal of Acupuncture
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• v.28 no.3
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• pp.1-12
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• 2011

Objectives : The purpose of this study is to review laser acupuncture studies to find possibility for applying high intensity laser to acupuncture and moxibustion treatment. Methods : Searching papers was performed using search engines of five electronic databases, including Pubmed, Thomson ISI, EMBASE, Sciencedirect, and EBSCO, from inception to May 2011 without language limitation. Inclusion criteria were clinical studies with human, randomized controlled trials (RCTs), case-control studies, and case reports. Selecting papers was performed with titles and abstracts in first step, scrutinize full text in second step, and then the extrated data was analyzed by two authors independently. The methodological quality for RCTs was evaluated using Jadad's scale. Results : Total 8 papers, (3 RCTs, 5 controlld studies, and 1 case reports), were finally selected. The study dealt with surgical laser, argon and $CO_2$ laser was one for each, with GaAs laser was two, and with new semiconductor laser, GaN, were four. The output range was from 110 mW to 15 W. The study diseases were alcohol addiction, knee osteoarthritis, bronchopneumonia and asthma for children, and circulation. All studies reported positive effect. The methodological quality in all RCTs was low because of below 3 points and all studies had few subject numbers. Conclusions : We suggest that high intensity laser can be applied to acupuncture and moxibustion. Further rigorous and well-designed study will be needed for various disease. The oriental medical society needs to take active measures to study and clinical application of acupuncture and moxibustion treatment with high intensity laser.

• Herbal Formula Science
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• v.28 no.4
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• pp.407-428
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• 2020

Objectives : The purpose of this study is to review the effect of Guaruhaebaekbaekju-tang (GHBJ), Guaruhaebaekbanha-tang (GHBH) and Jisilhaebaekgyeji-tang (JHGJ) by summarizing Korean and English articles. Methods : The study was based on 23 papers published since 1995. Papers were searched on seven domestic electronic databases including Koreantk, NDSL, RISS, KISS, OASIS, Koreamed and Library of Korea University and three international electronic databases including PUBMED, Embase and Science Direct. Results : 1. 23 research papers were collected, including 13 in vitro studies, 6 in vivo studies, 2 case reports and 2 literature studies. 2. GHBJ, GHBH and JHGJ showed significant myocardial protective and anti-hyperlipidemic and anti-inflammatory effects. In addition, researches on anti-oxidant, thrombosis, and atherosclerosis have been conducted in various ways. 3. It can be confirmed that these studies are related to Chest and back pain (胸背痛), Insomnia by chest paralysis (胸痺不得臥), Stabbing pain that radiates from chest to back (心痛徹背), Chest numbness (心中痞), Obstruction of qi in the chest (留氣結在胸), Fullness sensation in chest (胸滿) among the terms. Conclusion : Through these results, close association was found between classic description and modern research about GHBJ, GHBH and JHGJ, and the possibility of providing objective evidence was confirmed. To improve the quality of the study, large scale studies will be required to evaluate the authority of GHBJ, GHBH and JHGJ.

• Herbal Formula Science
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• v.25 no.2
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• pp.271-302
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• 2017

Objectives : Jakyakgamcho-tang has been used to treat muscular tension, spasm and pain. On this study, new clinical uses of Jakyakgamcho-tang were confirmed and the other pharmacological results were summarized by analysing trends of modern experimental studies and clinical studies. Methods : Papers related to Jakyakgamcho-tang were searched on PUBMED, RISS, and National Assembly Library, and classified by categories and effects of clinical application and a variety of experiment around abstract. Also, figures were used for sketching out a timeline of expressing when these papers were read and core research content was described as a digest for identifying research trends. Results : Until today, there are 104 researches about the antispasmodic, analgesic, anti-inflammatory effects of Jakyakgamcho-tang. In total, 91 papers were analyzed in this study. In matter of subject, researches on the antispasmodic effects were 17 cases, researches on the analgesic effects were 14 cases, researches on gynecological therapeutics were 14 cases, researches on pharmacokinetics were 12 cases, researches on the constituent identification were 7 cases, studies about constituents efficacy were 6 cases, studies about interactions with drugs were 6 cases. Conclusion : The traditional use of Jakyakgamcho-tang on muscle tension, spasm and pain has proven to have effects through the experimental evidences. Other effects of Jakyakgamcho-tang such as gynecological therapeutics, anti-inflammatory effects, are now emerging as a new area in clinical use. Futhermore as an auxiliary treatment, Jakyakgamcho-tang is a good alternative for muscle cramps during maintenance of hemodialysis, myalgia or arthralgia induced by anticancer drugs, amenorrhea induced by neuroleptics.

• Journal of the Korean Society for information Management
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• v.27 no.3
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• pp.103-123
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• 2010

Recently, research community in Korea has shown a rapid growth in collaborating with Asian countries. In this study, we analyzed research collaboration among Asian countries using network analysis of co-authored papers as well as subject categories. The network of co-authored papers among Asian countries over the 5-year period since 2005 revealed that Japan, China, and Korea were positioned at the central part of the network and highly productive in collaborative research. In the analysis of the subject categories of co-authored papers in four different Asian regions with 2009 data, physics and material science were found the most productive subject fields in collaborative research in Northeast Asia. On the other hand, medical science was the most collaborative subject field in the remaining Asian regions.

• Ceramist
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• v.22 no.3
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• pp.281-300
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• 2019

Surface enhanced Raman scattering (SERS) was first discovered in 1974 by an unexpected Raman signal increase from Pyridine adsorbed on rough Ag electrode surfaces by the M. Fleishmann group. M. Moskovits group suggested that this phenomenon could be caused by surface plasmon resonance (SPR), which is a collective oscillation of free electrons at the surface of metal nanostructures by an external light source. After about 40 years, the SERS study has attracted great attention as a biomolecule analysis technology, and more than 2500 new papers and 500 review papers related to SERS topic have been published each year in recently. The advantages of biomaterials analysis using SERS are as follows; ① Molecular level analysis is possible based on unique fingerprint information of biomolecule, ② There is no photo-bleaching effect of the Raman reporters, allowing long-term monitoring of biomaterials compared to fluorescence microscopy, ③ SERS peak bandwidth is approximately 10 to 100 times narrower than fluorescence emission from organic phosphor or quantum dot, resulting in higher analysis accuracy, ④ Single excitation wavelength allows analysis of various biomaterials, ⑤ By utilizing near-infrared (NIR) SERS-activated nanostructures and NIR excitation lasers, auto-fluorescence noise in the visible wavelength range can be avoided from in vivo experiment and light damage in living cells can be minimized compared to visible lasers, ⑥ The weak Raman signal of the water molecule makes it easy to analyze biomaterials in aqueous solutions. For this reason, SERS is attracting attention as a next-generation non-invasive medical diagnostic device as well as substance analysis. In this review, the principles of SERS and various biomaterial analysis principles using SERS analysis will be introduced through recent research papers.

• Journal of Physiology & Pathology in Korean Medicine
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• v.29 no.5
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• pp.361-369
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• 2015

Benign prostatic hyperplasia(BPH) is a common disease among male. However, its cause and treatment are not known and it is easy to relapse to the patients again after some treatment. Chinese has got an active research on BPH of traditional Chinese medicine. We researched the Chinese clinical papers from 2000 to 2014. After translating those papers, we analyzed total 45 papers by classifying those according to frequently used prescriptions, differentiation of symptoms, signs, addition and subtraction of each medicine and the quantity of frequently used medicines. Through this study it was to provide evidence in the diagnosis and treatment of BPH. The prescription of BPH was classified according to its stage. Mainly damp heat patterns(濕熱型) induce dysuria, Qi-stagnation and blood stasis patterns(氣滯血瘀型) induce pain, While Kidney deficiency patterns(腎虛型) induce sexual function disorder. This analysis report would be able to provide the basis of taking a research on BPH. In addition, it could be applied on a stereotype of BPH as well as a variety of symptoms with frequently used prescription and addition and subtraction of each medicine.

• Journal of Korean Medicine Rehabilitation
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• v.21 no.2
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• pp.203-210
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• 2011

Objectives : The aim of this study is to establish evidence-based guideline on infrared therapy on acupoints. Methods : We investigated all the articles in websites including Pubmed, China national knowledge Infrastructure(CNKI) and medical journals authorized by national research foundation of Korea. The key words are acupoints and infrared. For the first time, we withdrew some papers no relationship to key words by reading titles and abstracts. In the second, we only selected randomized clinical trials(RCT) published from 2000 to 2010. Results : Out of 62 papers, only 2 RCT were analyzed. One (RCT 1) was about depression patients with insomnia(jadad score: 1). The other(RCT 2) was about urimic pruritus patients(jadad score: 5). In RCT 1, experimental group was significantly better than control group. In RCT 2, there was not statistical signification between two groups. Conclusions : In reality, there were not many papers on infrared therapy applications. Further study just like RCTs may be needed to establish evidenced-based guideline on infrared.

• 한국노년학
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• v.28 no.4
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• pp.773-784
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• 2008

This paper is to suggest policy issues to be done in the future health policy for the elderly, analyzing contents of results suggested in academic papers published in Journal of the Korean Gerontological Society. Number of Papers published in the Journal is 61, occupying most of papers related with chronic disease, medical expenditures and health delivery system except dental and psychiatric health. Method used to be analyzed is mostly random sampling among community inhabitants or hospital patients. Policy issues are as follows in case of being based in the above analysis results. Firstly, it is necessary that the development of health promotion specialized for the elderly be developed and activated. Secondly, it is necessary that the primary health care system specialized for the elderly be constructed. Thirdly, it is necessary that the subacute care system specialized for the elderly be constructed after acute care services. Finally, it is necessary that the health care system specialized for the elderly in need of long-term care be constructed also.

• The Journal of Korean Obstetrics and Gynecology
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• v.22 no.4
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• pp.83-92
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• 2009

Purpose: The aim of this study was to review systemically journals on the studies for complementary and alternative medicine in the treatment of endometriosis. Methods: Through medical websites, foreign clinical literatures about complementary and alternative medicines of endometriosis were searched. The cite used was http://www.Pubmed.gov. And then they were divided into three groups. In vitro, in vivo, clinical studies. Results: 1. We researched 2 papers about in vitro. Both were used extract of herbal mixture. And they used CCL5, SE-1, COUP-TF, 17-$\beta$-HSD1, 17-$\beta$-HSD2 which were not commonly used in Korea. 2. We researched 8 papers about in vivo. Most of them used blood-activating stasis-dispelling medicine, just few used tonic medicine. And they used acupuncture which were not used in Korea. Most of Korean paper also used blood-activating stasis-dispelling medicine and rarely used tonic medicine. 3. We researched 19 papers about clinical studies. They had much more cases(average=60) than Korean paper. They were also used western medicine randomized sham-controlled trial. Conclusion: Afterward we need to study for comparing western medicine and herb medicine. And we concern about acupuncture therapy.