• Korean Journal of Medicinal Crop Science
• /
• v.19 no.3
• /
• pp.191-197
• /
• 2011

In this study, we investigated antioxidant activities and whitening effects of Acer mono sap by encapsulation of nanoparticles. Acer mono sap was through ultra high pressure process and then encapsulated by lecithin. Nano-encapsulated The nanoparticles of Acer mono sap showed highest free radical scavengering effect as 89.7% in adding sample (1.0 mg/ml), compared to sap of non-encapsulation. It was showed strong inhibition effect on melanin production test by Clone M-3 cells as 47.8%. High inhibitory of tyrosinase was also measured as 85.8% by adding lecithin nano-particle of 1.0 mg/ml. The nano-particles also showed 14.8% of low cytotoxicity against human normal fibroblast cells in adding 1.0 mg/ml of the highest concentration. These results indicate that Acer mono sap may be a source of cosmetic agents capable of improving whitening effect and antioxidant activites.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.18 no.8
• /
• pp.88-98
• /
• 2017

The purpose of this study is to investigate the effect of product selection of hospital workers cosmeceutical cosmetics on marketing communication among hospital workers who use cosmeceutical cosmetics that have emerged in line with the recent growing medical skin care field.Coping with complaints from consumers who buy cosmeceutical cosmetics in hospitals where cosmeceutical cosmetics are mainly used and sold, and minimizing the influence of negative issues will potentially strengthen consumer relationships. The study was conducted on 520 hospital workers who use cosmeceutical cosmetics in hospitals (dermatology, plastic surgery, women's clinic, and other hospitals) in Seoul, Gyeonggi and Incheon. A total of 502 questionnaires were used for the final analysis. The data analysis consisted of Cronbach's alpha, one-way ANOVA, exploratory factor analysis and Duncan test. Correlation analysis was performed to investigate the correlation between variables, and regression analysis was conducted to test hypotheses. The study results revealed that when choosing cosmetic cosmetics, marketing communication is influential. Especially, product value, quality, and price factors strongly affect marketing communication. This shows that we value the product and quality the most and we want a reasonable price. Considering this, we will pursue differentiated products only from cosmeceutical cosmetics and provide them as basic data necessary for securing potential customers and increasing the sales of cosmeceutical cosmetics in accordance with the changing trends.

• Korean Journal of Korean Medical Institute of Dermatology and Aesthetics
• /
• v.1 no.1
• /
• pp.145-157
• /
• 2005

Oriental cosmetics is based on oriental medical theory. In oriental medicine, skin reflects the condition of internal organ(臟腑) and qi-hyul(氣血). The oriental dermatology and aesthetics aim at the development of health and beauty using herbal medicine, acupuncture, chuna(推拿), qigong(氣功), and diet. And the oriental dermatology and aesthetics are related the branch of oriental medicine, such as oriental gynecology and oriental internal medicine.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
• /
• v.29 no.1
• /
• pp.81-92
• /
• 2016

Objectives : The purpose of this study is to confirm the moisturizing effects of Herbal cosmetics containing Sinhyotakrisan(SHTL) extracts on facial skin.Methods : A total of 23 women who visited Semyung Oriental Medical Center from January 10th, 2014 to Feburary 12th, 2014 were included in the study. Provided both cosmetics containing Sinhyotakrisan extract and control products, all the subjects applied one of them to half face and another to remaining half for 4 weeks. We observed change of skin hydration, skin elasticity, skin scale in 0 week, 2 weeks, and 4weeks. Statistical anyalysis was performed by using SPSS, and statistical significance was achieved if the proability was less than 5%(p<0.05).Results : 1. After 4 weeks of using SHTL, skin hydration showed a statistically significant increase compared with using control product(p=0.011). And improvement rate also did(p=0.031). 2. After 4 weeks of using SHTL, skin elasticity showed statistically significant increase compared with using control product(p=0.025). But improvement rate didn't showed statistically significant increase(p=0.068). 3. After 4 weeks of using SHTL, skin scale showed a statistically significant decrease compared with using control product(p=0.029). And improvement rate also did(p=0.047).Conclusions : Considering the above results, herbal cosmetics containing Sinhyotakrisan extracts were effective for skin moisturizing.

• YAKHAK HOEJI
• /
• v.52 no.3
• /
• pp.165-171
• /
• 2008

To develop effective skin whitening agents, we tested natural herbal extracts for their melanogenic inhibitory activities. Sedum samentosum was selected for its inhibitory effect on melanogenesis in B16 melanoma cells. Ethanolic extract of S. samentosum (SSE) was evaluated for antioxidative effect and tyrosinase inhibitory activity of melanogenesis. We investigated the changes in protein level and mRNA level of tyrosinase, tyrosinase related protein (TRP)-1 and TRP-2 by using western blotting and RT-PCR, respectively. SSE showed scavenging activities of free radicals and reactive oxygen species (ROS) with the $IC_{50}$ of 342.7 $\mug/ml$ against 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical and 64.69 $\mug/ml$ against superoxide radicals in the xanthine/xanthine oxidase system, respectively. SSE treatment suppressed the biosynthesis of melanin up to 46% and reduced tyrosinase activity up to 51% at 100 $\mug/ml$ in B16 melanoma cells. The tyrosinase activity and tyrosinase expression in B16 melanoma cells were reduced in a dose-dependent manner by SSE. Also, SSE was able to significantly inhibit tyrosinase and TRP-1 expression in mRNA level. These results suggest that SSE inhibited melanin production which may be dependent on tyrosinase activity and expression in B16 melanoma cells, and an effective whitening agent for the skin.

• Journal of the Korean Applied Science and Technology
• /
• v.40 no.3
• /
• pp.453-461
• /
• 2023

This study was to verify the skin safety of Coptis Japonica extract(CJE) -containing cosmetics by patching them on sensitive skin and checking its stimulating level. 32 subjects diagnosed with sensitive skin by the result of the lactic acid injury test, were subjected to 20 ㎕ of solubilized essence mixed with 2% CJE on the test subjects' back and closed patched for 24 hours. No stimulus reactions were found by bare eyes and scored 0 stimulus figure points after they were taken off in 30 minutes, 24 hours, and 48 hours. Coptis japonica's medical efficacies such as antioxidant, and anti-inflammatory are expectable to be used as functional cosmetics, and this research would be the foundation of further research into its cosmetical usage.

• Journal of the Korean Applied Science and Technology
• /
• v.37 no.6
• /
• pp.1528-1534
• /
• 2020

This study examines the trends of the domestic age-friendly industry, examines the ingredients notified by the Ministry of Food and Drug Safety of aging cosmetics, and analyzes the research trends of raw materials other than the notices, and prepares data for the aged-friendly industry to quickly cope with changes in the cosmetics industry environment and aging people. I wanted to. In addition to the ingredients notified by the Ministry of Food and Drug Safety, research trends on the development of ingredients for anti-aging cosmetics are examined, and the anti-aging effects of each ingredient are examined. Through this, 'aging' and 'cosmetics', 'Anti-Aging', 'Anti-Aging', etc. In order to lead the development of anti-aging cosmetics related to the aging industry, research activities on products that are effective in preventing aging by strengthening the skin in addition to the four ingredients notified by the Ministry of Food and Drug Safety are constantly being conducted. In the functional cosmetics field notified by the Minister of Food and Drug Safety, it is believed that various basic research activities should be conducted so that research on anti-aging can be scientifically supported rather than a single research.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
• /
• v.21 no.3
• /
• pp.124-131
• /
• 2008

Objectives : The aim of this study was conducted to test dry infant skin by external application with herbs in cosmetics. Methods : A total of 25 infants who visited Daegu Hanny Oriental Medical Center from March 5th, 2008 to May 18th, 2008 were included in this study. In this study, they were treated with the cosmetic products(body wash, rotion, cream) containing herbs. For 4 weaks skin moisture content was measured by corneometer ClVI825. And satisfaction after using body wash, rotion, cream was checked. Results : There were no significant differences on sex and age. Change of skin moisture content between before treatment and after treatment (2, 4 weeks) showed significant changes(p<0.05). Satisfaction after using body wash, rotion, cream was near good. Conclusions : Considering the above results, we have concluded that cosmetics containing herbs have the remarkable effect on infant skin mosturizing.

• YAKHAK HOEJI
• /
• v.49 no.2
• /
• pp.174-179
• /
• 2005

The human skin is constantly exposed to environmental irritants such as ultraviolet, smoke, chemicals. Free radicals and reactive oxygen species (ROS) caused by these environmen tal facts play critical roles in cellular damage. These irritants are in themselves damaging to the skin structure but they also participate the immensely complex inflammatory reaction. The purpose of this study was to investigate the skin cell protective effect of Campsis grandiflora extract on the UVB-irradiated human dermal fibroblasts (HDFs). We tested free radical and superoxide scavenging effect in vitro. C. grandiflora extracts had potent radical scavenging effect by 82% at $100{\mu}g/ml$, respectively. For testing intracellular ROS scavenging activity the cultured HDFs were analyzed by increase in DCF fluorescence upon exposure to UVB 20 $MJ/cm^2$ after treatment of C.grandiflora extracts. The results showed that oxidation of CM-DCFDA was inhibited by C.grandiflora extracts effectively and C.grandiflora extracts has a potent free radical scavenging activity in UVB- irradiated HDFs. In ROS imaging using confocal microscope we visualized DCF fluorescence in HDFs directly. In conclusion, our results suggest that C.grandiflora can be effectively used for the prevention of UV-induced adverse skin reactions such as radical production, and skin cell damage.

• Proceedings of the Korea Contents Association Conference
• /
• 2006.11a
• /
• pp.47-51
• /
• 2006

As the recent announcement of the functional cosmetics law, the need of studies on efficacy evaluation of skin related cosmetics and medical supplies has grown. Especially to identify skin improvement, we have to compare the exact parts of the skin, however up to now it is compared only by image matching that is appeared to the human eye. This study proposes the automatical image matching system for improving the accuracy of evaluation a skin improvement. Firstly we define the feature of the skin pores and wrinkles, and extract anticipation region from skin images. And then, we calculate moments for each extracted regions and classify them as pores and wrinkles. After that, we calculate the vector by computing centroids between each regions. Through this process, we compare the vector similarities and perform the matching between existing image and reference image. To verify the efficiency of the algorithm several experiments are conducted.