• Proceedings of the KOSOMBE Conference
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• v.1995 no.05
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• pp.19-22
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• 1995

A biomechanical study was made to demonstrate the superior mechanical performance of the newly designed Miniplate staple to the conventional Coventry staple in high tibial osteotomy(HTO). Using twenty fresh porcine tibiae, the fixational strengh of the two different types of staple in HTO was compared. To minimize the error due to the specimen-to-specimen individuality, the bone mineral density of the tibiae was measured with a bone densitometry (Dual photon absorptionometer, Luner, USA) and those with $0.8\;{\sim}\;1.2\;gm/cm^2$ at the proximal tibia was used in the biomechanical test. Testing was performed on a material testing system (Autogram ET-5, Shimatzu, Japan) with aid of a commercial data processor (IBM 80386/ ASYST). Using two differant loading modes, 'pull-out' and 'push-out', the maximum resistant force required to release the staple from the substrate bone was recorded. In the pull-out test, ten non-osteotomized specimens were used and the staple was pullout by subjecting an axial tension on the head of the staple inserted. While in the pull-out test where ten tibiae osteotomized in the usual way of HTO were used, the staple was not directly loaded. In this testing, as a mimic condition of the natural knee, the distal part of the specimen tibia was pushed horizontally in order for the staple to be pulled out while the proximal tibia was fixed. The pull-out strength of Coventry staple and miniplate staple were found to be $27.88\;{\pm}\;5.12\;kgf$ and $182.47\;{\pm}\;32.75\;kgf$, respectively. The push-out strength of Coventry staple and miniplate staple were $18.40\;{\pm}\;4.47\;kgf$ and $119.95\;{\pm}\;19.06\;kgf$, respectively. The result revealed that miniplate staple had the pull-out/ push-out strength at least fivetimes higher than Coventry staple. Based on the measured data, it was believed that the newly designed miniplate staple could provide much better postoperative fixation in HTO. The postoerative application of long leg casting may not be needed after HTO surgery.

• Journal of Microbiology and Biotechnology
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• v.20 no.12
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• pp.1653-1663
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• 2010

The first gene (${\alpha}$-gal1) encoding an extracellular ${\alpha}$-Dgalactosidase from the thermophilic fungus Talaromyces emersonii was cloned and characterized. The ${\alpha}$-gal1 gene consisted of an open reading frame of 1,792 base pairs interrupted by six introns that encoded a mature protein of 452 amino acids, including a 24 amino acid secretory signal sequence. The translated protein had highest identity with other fungal ${\alpha}$-galactosidases belonging to glycosyl hydrolase family 27. The ${\alpha}$-gal1 gene was overexpressed as a secretory protein with an N-terminal histidine tag in the methylotrophic yeast Pichia pastoris. Recombinant ${\alpha}$-Gal1 was secreted into the culture medium as a monomeric glycoprotein with a maximal yield of 10.75 mg/l and purified to homogeneity using Hisbinding nickel-agarose affinity chromatography. The purified enzyme was maximally active at $70^{\circ}C$, pH 4.5, and lost no activity over 10 days at $50^{\circ}C$. ${\alpha}$-Gal1 followed Michaelis-Menten kinetics ($V_{max}\;of\;240.3{\mu}M/min/mg,\;K_m\;of\;0.294 mM$) and was inhibited competitively by galactose ($K_m{^{obs}}$ of 0.57 mM, $K_i$ of 2.77 mM). The recombinant T. emersonii ${\alpha}$-galactosidase displayed broad substrate preference, being active on both oligo- and polymeric substrates, yet had strict specificity for the ${\alpha}$-galactosidic linkage. Owing to its substrate preference and noteworthy stability, ${\alpha}$-Gal1 is of particular interest for possible biotechnological applications involving the processing of plant materials.

• Journal of Ginseng Research
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• v.41 no.4
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• pp.456-462
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• 2017

Background: Abnormal activation of matrix metalloproteinases (MMPs) plays an important role in UV-induced wrinkle formation, which is a major dermatological problem. This formation occurs due to the degeneration of the extracellular matrix (ECM). In this study, we investigated the cutaneous photoprotective effects of Ultraflo L treated ginseng leaf (UTGL) in hairless mice. Methods: SKH-1 hairless mice (6 weeks of age) were randomly divided into four groups (8 mice/group). UTGL formulation was applied topically to the skin of the mice for 10 weeks. The normal control group received nonvehicle and was not irradiated with UVB. The UV control (UVB) group received nonvehicle and was exposed to gradient-UVB irradiation. The groups (GA) receiving topical application of UTGL formulation were subjected to gradient-UVB irradiation on $0.5mg/cm^2$ [GA-low (GA-L)] and $1.0mg/cm^2$ [(GA-high (GA-H)] of dorsal skin area, respectively. Results: We found that topical treatment with UTGL attenuated UVB-induced epidermal thickness and impairment of skin barrier function. Additionally, UTGL suppressed the expression of MMP-2, -3, and -13 induced by UVB irradiation. Our results show that topical application of UTGL protects the skin against UVB-induced damage in hairless mice and suggest that UTGL can act as a potential agent for preventing and/or treating UVB-induced photoaging. Conclusion: UTGL possesses sunscreen properties and may exhibit photochemoprotective activities inside the skin of mice. Therefore, UTGL could be used as a potential therapeutic agent to protect the skin against UVB-induced photoaging.

• Journal of Convergence for Information Technology
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• v.10 no.7
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• pp.240-248
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• 2020

This study compares and analyzes the tasks and evaluation methods of national technically qualified Skin Esthetic through systematic literature review of prior studies on qualification tests for Skin Esthetic qualification and process evaluation types that have been reorganized based on NCS. The national technical qualification is based on the ability to work through memorization-oriented theoretical tests and simple repetition of functions, and the Qualified qualification is relatively short in the period of test execution, and the reliability of its internal evaluation at the enforcement agency continues to be reduced. In the future, national technical qualification require innovation in the qualification system to reflect skilled demand at industrial sites, and course-based qualification for require supplementation and improvement of education and training courses so that they can learn skilled skills at the site.

• Journal of Digital Convergence
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• v.16 no.10
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• pp.357-366
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• 2018

The purpose of this study is to provide data for the development of a nursing intervention program by analyzing the concept of prisoner correction. From April 1st, 2016, to July 30th, the research literature on all domestic and international prisoner correction from 2011 to 2015 were searched using PubMed and NDSL RISS. 37 documents were analyzed according to conceptual analysis method procedures by Walker and Avant. In order to promote a positive attitude toward life through internal reflection of prisoner correction, individual characteristics for improvements in problem solving abilities, social adaptation abilities, re-socialization and the protection of the people and society to inmates displaying anti-social and moral behaviors that violated the law. The purpose of this study was to establish a desirable direction for prisoner correction, and provide a theoretical basis for the development of a nursing intervention program.

• Journal of Korean Public Health Nursing
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• v.20 no.1
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• pp.5-15
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• 2006

Purpose: The objectives of this study was to measure the outcomes of interventions on the health and social welfare of the elderly in a rural community in Korea. The project involved integrating services of one public health center with that of one social welfare agency, which were under different administrative structures. Method: A single group pretest-posttest design was used for this research. Seventy-five elderly residents living alone in a rural community participated in the study. All of them had coverage of free basic medical care and social welfare services by the government. Major activities for the intervention included: developing partnerships among community leaders/institutes; forming committees of community residents; educating care providers and volunteers; developing 8 integrated service programs and instruments; and organizing the networks. The 20-month intervention was care-managed by a public health nurse whom collaborated with social worker, and was assisted by volunteers. The t-test was utilized to analyze the outcome variables including the elder's health, social welfare and quality of life. A major limitation of this study was the lack of a control group. Results: The outcome of the intervention was shown by improved elder's health, social welfare needs, and quality of life. Integrating the services of public health centers with those of social welfare agencies is an effective way to improve the health of the elderly in the community. Conclusion: Developing community capacity with such integrated services will pay an important role in improving the health of the elderly who live alone.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.26 no.4
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• pp.397-403
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• 2015

In this paper, a method of ISAR geometric calibration is represented by using impulse-radio UWB radar. The ir-UWB is good for using a signal processing in time domain, so, it does not occur a multi-path or coupling problem. If a signal that between antennas and target is assumed a plane wave, a center of rotation in ISAR geometry model can be estimated by using point target. Before image is reconstructed with sinogram, the center of rotation can be calculated by using least square fitting. This method can be obtained a more contrast image, and a maximum value of entropy of image. The method, that estimates a center of rotation in received data, will be used a initial setup of instruments or a periodic compensation to reconstruct image. It would be useful in medical, security and surveillance imaging equipments that have a fixed geometry.

• Korean Journal of Occupational Health Nursing
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• v.8 no.2
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• pp.176-192
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• 1999

The purpose of this study is to analysis change of industrial health and safety before and after economic crisis(1997~1998). The data were obtained through mail interview with health supervisor(occupational health nurses) during February, 1999. The final sample was consisted of 127 respondents, 97 are selected in this study. The major findings were as follows: First, the percent of industries whose empl safe supervisors, physicians and industry hygi decreased in number is 79.4%, 3.8%, 50.0 21.5% in each. Second, man receiving over 1.5 million won as an average wage of health supervisor is 27.5% in 1997, but it decreased to 25.3% in 1998. Man receiving under 100~150 million won is 48.4% in 1997, but this percent decreased to 36.3% in 1998 and 13.6% of health supervisor regularly were transformed to contingent worker in 1998. Third, especially, budgets for health and saf work place decreased to 13.8% in 1998 than 19. Fourth, industrial accident case, unre accident case, occupational disease decreased than 1997, but mortality from industrial a increased in 250%. Fifth, according to the health diagnosis report, number of case with evidence of disease increased in liver disease, tuberculosis and so on, and number of case with evidence of occupational disease increased in noise induced hearing loss, pneumoconiosis. organic solvent poisoning and so on. Sixth, this survey shows that health council, health education in duty of health supervisor was conducted passive in 1998 thin 1997, and percent of hold two or more positions is 47.6% in medical insurance, 10.7% in accountant's business 8.3 in secretory. 7.1% in telephone operator awl 22.6% in etc. Seventh, distress of health supervisor after economic crisis is 30.9% in employment instability, 19.8% in hold two or more positions and decrease of budgets. For subjugation of the trouble, the respond of active policy of government occupied most.

• Tuberculosis and Respiratory Diseases
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• v.81 no.1
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• pp.19-28
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• 2018

Cancer is the leading cause of death in the Republic of Korea and cancer death accounts for 27.8% of the total deaths, which is not only a social issue but also a concern for the public. Among the cancer death rates, lung cancer mortality account for 34 deaths per 100,000 populations, making it the number one cancer death rate. In a preliminary report on cancer death in 2012, the lung cancer mortality ratio showed the regional variation indicating that there were differences in the qualitative level and the structure among the medical care benefit agency and in the assessment of the treatment process. Therefore, the Health Insurance Review and Assessment Service (HIRA) had begun evaluation of the assessment of lung cancer treatment since 2014 to improve the quality of lung cancer care through evaluation and feeds back the results of lung cancer care process. In this report, authors described the current Indicators for the lung cancer adequacy assessment proposed by HIRA and results of the evaluation reported in 2017.

• Journal of Digital Convergence
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• v.11 no.7
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• pp.173-184
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• 2013

Quantum Information Processing and Communication, based on the physical laws of Quantum mechanics, exploits fundamentally new modes of computation and communication and holds the promise of immense computing power beyond the capabilities of any classical computer. In Quantum Information Processing, replacing bits with qubits, one makes two-state quantum systems that do not possess in general the definite values of 0 or 1 of classical bits, but rather are in a so-called. "coherent superposition", of the two. Full exploitation of this additional freedom implies that new processing devices need to be designed and implemented, and that a large scale quantum computer can in principle be built. New discoveries will enable a range of exciting new possibilities including: greatly improved sensors with potential impact for mineral exploration and improved medical imaging and a revolutionary new computational paradigm that will likely lead to the creation of computing devices capable of efficiently solving problems that cannot be solved on a classical computer. In short, Quantum computing is an economy game changer, with a potential of disrupting entire industries and creating new ones.