• Asian Pacific Journal of Cancer Prevention
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• v.15 no.23
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• pp.10251-10254
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• 2015

Uterine cancer is the most common invasive gynaecological cancer in Australia. Early detection is a key predictive factor achieved by increasing public awareness and participation in screening. This observational study measures awareness of gynaecological malignancies, particularly uterine, among women in two rural areas of New South Wales, Australia. Patients presenting to gynaecology clinics in January to March 2014 were invited to complete a structured questionnaire. Women with a history of cancer and incomplete questionnaires were excluded. Of the 382 patients invited to participate, 329 (86%) responded with complete feedback. Most respondents were younger than than 50 years (66%) and married with at least 2 children (74%). The majority (94%) of participants had no awareness of uterine cancer and many (46%) were unable to identify common risk factors including obesity, diabetes and hypertension. The ability to identify risk factors was correlated to age, marital status and obesity. The study identifies poor awareness on uterine malignancies in two typical areas of rural Australia. Although external validity is limited by sociological factors, poor awareness of uterine cancer among rural patients in this study represents a valid public health concern. It is imperative to improve awareness of uterine cancer and available screening programs to facilitate early detection and cure.

• The Journal of Korean Medicine
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• v.29 no.4
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• pp.104-113
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• 2008

Objectives: The aim of this study was to investigate the influence of five herbal medicines on cytochrome P450 (CYP) 3A4 drug-metabolizing enzymes in human liver microsomes. Methods: By using of human liver microsomes, we extracted Cnidium officinale Makino, Rhus verniciflua Stokes, Prunus persica Batsch, Corydalis remota Fisch, Carthamus tinctorius Linne, which are called Hwalhyulgeoouhyak(活血祛瘀藥). Then they were incubated and measured for relative enzyme activity under incubation conditions compared to ketoconazole, which is known as a representative inhibitor of CYP 3A4. Results: We showed that all of five traditional herbal medicines had no inhibition effect of CYP 3A4 at 10, 20, 30, 40, and 50${\mu}g/m{\ell}$ doses in human liver microsomes, although Rhus verniciflua Stokes (RVS) showed a little inhibition as about 95% enzyme activity of control. However, this result was not enough to prove that RVS has a CYP 3A4 inhibition effect. Moreover, we can't confirm that those rates have significant induction effect on CYP 3A4. Conclusions: The result of this study could support that those herbal medicines are more reliable than chemical drugs, even if this is a basic step to prove that result.

• Clinical and Experimental Pediatrics
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• v.48 no.10
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• pp.1050-1054
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• 2005

Purpose : Relactation refers to the re-establishment of a milk supply and nursing after the cessation of nursing for a variable period. We aimed to analyze the practical issues related to successful relactation in the lactation clinic. Methods : The medical records of 51 mothers who had visited the lactation clinic for relactation were retrospectively analyzed. Breastfeeding greater than 90% was considered to as relactation success. Perinatal characteristics, the number of visits to the clinic, need for medication and the breastfeeding supplementer, and the reason for failure were analyzed. Results : Relactation appears to be easier for women who had lactated previously. With optimal care, support and motivation, some who had never lactated were able to start lactation. Conclusion : Relactation is a practical method to ensure breastfeeding in motivated women. Supplemental use of drugs and the breastfeeding supplementer system contribute to the success of relactation.

• Journal of Korean Neurosurgical Society
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• v.59 no.3
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• pp.269-275
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• 2016

Objective : Although middle cerebral artery (MCA) aneurysms are less amenable to coil embolization, an increasing number of studies support favorable endovascular treatment for them. The purpose of this study is to compare the outcomes of two different treatments (surgery versus coiling) and evaluate the benefits of surgical clipping for MCA aneurysms. Methods : Here we retrospectively analyzed the outcomes of 178 ruptured and unruptured MCA aneurysms treated in patients between September 2008 and April 2012. Parameters assessing treatment outcomes include degree of aneurysm occlusion, presence of regrowth, clinical status, and complications. Results : Among 178 MCA aneurysms, 153 were treated surgically. After a mean follow-up of 12 months, the surgery group showed a clinically significant complete occlusion rate (98%) compared with the coiling group (56%) (p<0.001). Follow-up radiologic evaluation showed a higher regrowth rate (four of 16 cases) in the coiling group than in the surgery group (one of 49 cases) (p=0.003). There was no statistically significant difference in favorable clinical outcome rate between the two groups. The procedure-related permanent morbidity and mortality rates were 2% (three of 153 cases) in the surgery group and 0% (0 of 25 cases) in the coiling group. Conclusion : Compared to endovascular treatment, surgical neck clipping for both ruptured and unruptured MCA aneurysms results in a significantly higher complete obliteration rate and less regrowth. Therefore, even in this endovascular era, we still recommend surgical clipping as the primary treatment option for MCA aneurysms rather than coil embolization.

• Journal of Multimedia Information System
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• v.6 no.4
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• pp.293-302
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• 2019

In the past, there was a theory that influenza wasn't transmitted directly from birds but was infected to humans via swains. Recently, molecular level research has progressed, and it was confirmed that the avian influenza virus can directly infected to human lung and intestinal epithelial cells. Three pandemicsin the past 100 years were also infected to humans directly from birds. In view of such scientific background, we are developing a method for screening sick birds by monitoring the physiological characteristics of birds in a contactless manner with sensors. Here, the movement of respiratory muscles and abdominal muscles under autonomic innervation was monitored using a magnet and Hall sensor sewn on the thoracic wall, and other multimedia devices. This paper presents and discusses the results of experiments involving continuous periodic noise discovered during flight experiments with a data logger mounted on a Japanese pheasant from 2012 to 2015. A brief summary is given as the below: 1. Magnet and Hall sensor sewn to the left and right chest walls, bipolar electrocardiograms between the thoracic walls, posterior thoracic air sac pressure, angular velocity sensors sewn on the back and hips, and optical reflection of LEDs (blue and green) from the skin of the hips allow observation of periodic vibrations(fasciculations) in the waves. No such analysis has been reported before. 2. These fasciculations are presumed to be derived from muscle to maintain and control air sac pressure. 3. Since each muscle fiber is spatially Gaussian distributed from the sympathetic nerve, the envelope is assumed to plot a Gaussian curve. 4. Since avian trunk muscles contract periodically at all time, we assume that the sympathetic nerve dominates in their control. 5. The technique of sewing a magnet to the thoracic wall and measuring the strength of the magnetic field with a Hall sensor can be applied to screen for early stage of avian influenza, with a sensor attached to the chicken enclosure.

• Journal of Biomedical Engineering Research
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• v.24 no.5
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• pp.391-399
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• 2003

Intravascular oxygenation represents an attractive. alternative support modality for therapy originated with acute respiratory distress syndrome(ARDS). However. the clinical study concluded that more gas exchange was needed for intravascular oxygenation to be clinically effective in ARDS treatment. In this study, we tried to enhance gas exchange on the VIVLAD using microencapsulation of hemoglobin and perfluorocarbon emulsion(PFC emulsion). Blood gas measurements were performed by collecting blood samples from the arterial and venous sides of the circuit, and processing them in a blood/gas analyzer. The function of hemosome. blood/hemosome mixed solution. and blood/PFC emulsion mixed solution were tested by an oxygen dissociation curve using a blood/gas analyzer. As a result, it was shown that the oxygen transfer of hemosome and blood/hemosome mixed solution were higher than that of whole blood. Also. it showed that the carbon dioxide transfer of whole blood/PFC emulsion mixed solution was higher than that of others. Therefore, we determined that hemosome and PFC emulsion could increase oxygen transfer and carbon dioxide transfer. respectively.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.10
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• pp.4935-4942
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• 2013

The purpose of this study is to verify the effects of hospital employees' communication satisfaction on their perceived organizational effectiveness. Four research hypothesis are established for the purpose of this study. The subject of this study were 473 employees who were working at 10 general hospitals in Korea. The survey was done with structured questionnaire from January 3 to February 8, 2013. The results of stepwise regression analysis show that hospital employees' communication satisfaction positively affected organizational effectiveness. Interaction effects between employees' communication satisfaction and work types had stronger effect on organizational growth than organizational stability. It can be pointed out as an important issue that communication satisfaction score of medical support occupation is the lowest level(3.11 points out of 5 points). If hospitals want an integration of organization, it is required to develop method or skill to increase communication satisfaction among employees.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.5
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• pp.86-92
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• 2017

As the elderly population increases, real-time personal health monitoring is gaining new ground with advances in wireless communications. Such an approach is particularly beneficial to elderly and physically challenged people, as well as those who live alone and are not be able to seek help in case of medical emergencies. The aim of this study is to implement a wearable band which monitors personal vital signs, such as the body temperature and heart rate, and assists with healthcare decisions using a fuzzy logic based decision support system. Since the vital sign data measured from sensors are imprecise and their normal variation with age is nonlinear and not crisp, a fuzzy system is employed to deal with this imprecise or uncertain information. The proposed wearable band is designed to continuously capture and transmit vital signs and healthcare decisions to suitable apps developed for smartphones. In this way, health alerts can be sent to the guardian or caregiver who is registered in the apps.

• YAKHAK HOEJI
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• v.52 no.4
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• pp.283-287
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• 2008

Drug identification service and other drug-related query service are becoming increasingly important in hospital pharmacy. The goal of this research was to investigate current situation of the service in hospital pharmacy, which recently implemented the services as part of provision of advanced hospital pharmacy service in order to assure national health improvement. We investigated the report performed from November 2006 through April 2007 in a university hospital located in Daegu, Korea. Number of drug identification service performed was 81 cases during the first three months period (period I), but it increased to 222 cases during the second three months period (period II), which suggested that the service was welcomed by medical staff in the hospital. Time to process each case was about 30 minutes in the period I while it was only 16 minutes in the period II. Proportion of the unidentifiable cases remained at about 25% during the entire period, which suggests that the system for the identification task appears to have some limitations such as unsatisfactory support from the Korea Pharmaceutical Association, laws, and regulations. A vast majority of drug-related queries were mostly from physicians (60.5%) followed by nurses and pharmacists. Time to process each drug-related query was 10.6 minutes in the period I while it was 6.9 minutes in the period II. Queries answered immediately were about 70% of all queries in the period I, but increased to about 85% in the period II.

• Journal of the Korea Society for Simulation
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• v.25 no.2
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• pp.51-61
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• 2016

With high interest in the patient satisfaction of emergency medical services, there is a lot of effort into improving the process of Emergency Department(ED) utilizing the technology of Internet of Things(IoT). In this study, the core technologies of smart ED are examined and a decision support algorithm for medicine tasks is proposed. The proposed algorithm minimizes the decision risks such as task selection accountability, patient complaints, care delays and longer stay time. It can reduce the nurses burnout and improve the patient care with kindness and consideration. Ultimately, patient satisfaction, job satisfaction and professional identity of nurses can be increased. The comparative study was carried out by simulation in terms of the average length of patient stay in a simplified hypothetical ED system. In all the cases, the proposed algorithm was shown to perform substantially better than the other rule.