• 대한의용생체공학회:의공학회지
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• 제33권2호
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• pp.72-77
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• 2012

Phase Contrast MR Angiography(PC MRA) is excellent MRA technique for measuring the velocity of vessels in the human body. PC MRA need to at least four images for angiogram reconstruction and it caused longer scan time. Therefore, we used keyhole imaging combined PC MRA to reduce the scan time. However, keyhole imaging can lead the erroneous effects as loss of phase information or frequency discontinuous. In this study, we applied the keyhole imaging combined 2D PC MRA for improving the temporal resolution and also measured the velocity to evaluate the accuracy of phase information. We used 0.32T MRI scanner(Magfinder II, Scimedix, Korea). Using the 2D PC MRA pulse sequence, the vascular images for a human brain targeted on the Superior Sagittal Sinus(SSS) were obtained. We applied tukey window function for keyhole images to minimize the ringing artifact and erroneous factors that are induced frequency discontinuous and phase information loss. We also applied zero-padded algorithm to peripheral missing k-space lines to compare keyhole imaging results and the artifact power(AP) value was measured on the complex difference images to validate the image quality. Consider as based on our results, heavy image distortions and artifacts were shown until using at least 50% keyhole factor. Using above the 50% keyhole factors are shown well reconstructed and matched for magnitude images and velocity information measurements. In conclusion, we confirmed the image quality and velocity information of keyhole technique combined 2D PC MRA. Especially, measured velocity information through the keyhole imaging combination was similar to the velocity information of full sampled k-space image despite of frequency discontinuous and phase information loss in the keyhole imaging reconstruction process. Consequently, the keyhole imaging combined 2D PC MRA will give some clinical usefulness and advantages as improving the temporal resolution and measuring the velocity information via selecting the appropriate keyhole factor at low tesla MRI system.

• 대한디지털의료영상학회논문지
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• 제11권2호
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• pp.115-119
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• 2009

I think this will be valuable reference for assuring consistency and homogeneity of clarity and managing dental radiation equipment by experimentation of dental radiation equipment permanent which based on KS C IEC 61223-3-4 standard and KS C IEC 61223-2-7. Put a dental radiation generator and experiment equipment as source and film(sensor) length within 30 em, place the step-wedge above the film(sensor). Tie up tube voltage 60 kVp, tube current 7 mA and then get an each image through CCD sensor and film by changing the exposure time as 0.12sec, 0.25sec, 0.4sec. Repeat the test 5times as a same method. Measure the concentration of each stage of film image, which gained by experiment, using photometer. And the image that gained by CCD sensor, analyze the pixel value's change by using image J, which is analyzing image program provided by NIH(National Institutes of Health). In case of film, while 0.12sec and 0.25sec show regular rising pattern of density gap as exposure time's increase, 0.4sec shows low rather than 0.12sec and 0.25sec. In case of CCD sensor density test, the result shows opposite pattern of film. This makes me think that pixels of CCD's sensor can have 0~255 value but it becomes saturation if the value is over 255. The way that getting clear reception during decreasing human's exposed radiation is one of maintaining an equipment as a best condition. So we should keeping a dental radiation equipment's condition steadily through cyclic permanent test after factor examination. Even digital equipment doesn't maintain a permanent, it can maintain a clarity by post processing of image so that hard to set it as standard of permanent test. Therefore it would be more increase the accuracy that compare a film as standard image. Thus I consider it will be an important measurement to care for dental radiation equipment and warrant homogeneity, consistency of dental image's clarity through comparing pattern which is the result from factor test against cyclic permanent test.

• 전자공학회논문지S
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• 제35S권5호
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• pp.42-47
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• 1998

Bridcage RF coil is one of the most widely used RF coils in MRI. In order to use birdcage RF coils in open MRI systems, an open tructured birdcage RF coil has been investigated. By opening the ring structure of an original birdcage RF coil and driving the coil at two opening ends, the original birdcage RF coil can be modified to an open structured coil. In order to improve magnetic field uniformity of the open birdcage RF coil, driving voltage phases at the two opening ends can be controlled to be in-phase or out-of-phase each other. Operating frequency of the open birdcage RF coil has been theoretically derived, and the theoretical derivation has been verified by experiments.

• 대한디지털의료영상학회논문지
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• 제12권2호
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• pp.81-87
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• 2010

The setting parameters of ultrasound scanner give influences to change of image. Sonographers have used a Matlab program to make Low Contrast Sensitivity(LCS) value and compared original images in order to evaluate the use of the supersonic diagnosis machinery. We confirmed the change of image in Grayscale values using Photoshop program. Experiment equipment of our research used A Medison Accuvix V10, A Multi-Tissue Ultrasound Phantom(040 GSE) of CHRIS Company, A Adobe Photoshop CS4 Program, A Convex Probe, A USB memory stick, A Probe Fixation Equipment. The method used Gain, Dynamic Range(DR) of the setting parameters of ultrasound scanner and researched Gain and DR was set to 10 dB. We changed the different settings to see the changes of images using Grayscale values of a Photoshop program about tissue images of a phantom. This study evaluated DR and Gain whether it is an image controller to get the optimum contrast to produce an image to see the how effect on the images. We did not use Gateway in supersonic diagnosis machinery. We can easily open to open the files through Photoshop program before we get Digital Imaging and Communications in Medicine(DICOM) files use USB memory stick in supersonic diagnosis machinery. When we diagnosed the lesion of the patient with ultrasound, the contrast and the Gray scale value of image are very important. In this research, we determined the optimum setting parameters that provided useful information to diagnose disease and evaluated the change of improved images.

• 대한방사성의약품학회지
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• 제2권2호
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• pp.118-122
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• 2016

Integrin ${\alpha}_v{\beta}_3$ plays an important role in the tumor metastases and angiogenesis. Arginine-glycine-aspartate (RGD) peptide motif binds to the integrin ${\alpha}_v{\beta}_3$. General $^{68}Ga$-labeled cyclic RGD peptides was rapidly eliminated from the circulatory system by renal excretion because of its hydrophilic property. The purpose of this study was to develop a novel $^{68}Ga$-labeled cyclic RGD peptides, which could acquire enhanced PET tumor images with improved pharmacokinetics by adopting biphenyl group between chelator and RGD peptides. $^{68}Ga$-DOTA-2P-c(RGDyK) was demonstrated a 12% higher lipophilicity level than $^{68}Ga$-DOTA-c(RGDyK) as a reference compound. In the animal PET, $^{68}Ga$-DOTA-2P-c(RGDyK) represented relatively lower blood-clearance, and an increased signal to noise ratio compared to $^{68}Ga$-DOTA-c(RGDyK). From these perspective, $^{68}Ga$-DOTA-2P-c(RGDyK) could be a good candidate for in integrin ${\alpha}_v{\beta}_3$-expressed tumor imaging.

• Nuclear Medicine and Molecular Imaging
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• 제43권5호
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• pp.451-458
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• 2009

목적: 광학적 분자 발광영상은 발광효소를 이용하여 발광하는 빛의 신호를 영상화하는 기법이다. 발광하는 광량이 분자 변화 또는 세포 수와 비례하고 신호 대 잡음비가 좋아서 영상을 얻고, 정략분석이 가능하다. 이 연구에서는 정량적 분석을 위해 비례적 측정 정량화기법을 개발하였다. 대상 및 방법: 개발 중인 ALIS (animal light imaging system) 광학발광영상 카메라에서 박테리아 수를 달리한 박테리아 광원 3가지와 또 다른 3가지 광원을 이용하여 발광영상을 측정하였다. 일정한 세기의 광원에 대해서 측정 방법을 수학적으로 표현하기 위해 cd와 광속의 개념을 이용하여 간단한 수식을 유도하였다. 실험을 통해 측정시간 1초를 기준으로 얻어진 값으로 표준 정량화 함수를 얻었다. 얻어진 정량화 함수를 이용하여 박테리아를 이용한 실험에 필요한 함수의 상수 값을 구했으며, 세 가지 세기가 다른 광원을 이용하여 측정한 값을 측정시간과 함께 정량화 식에 대입하여 측정하였다. 결과: 표준측정함수를 이용하여 측정시간에 비례하는 정량적 값을 얻을 수 있었다. 정량화결과를 측정시간으로 나눠준 값은 일정하였으며, 측정시간에 대비한 비례적 값을 얻을 수 있었다. 결론: 측정한 결과를 정량화 함수에 대입하여 정량화시킨 값은 표준정량화 하기에 적합하였다. 이 정량화 방법은 다른 광학적 분자영상 장비에 적용하여도 빛의 세기를 표준화 시킬 수 있을 뿐 만 아니라 성격이 다른 각각의 광원에 대해서도 보다 정량적인 분석을 시행할 수 있으므로, 새로운 표준 정량화 방법으로 발전시킬 수 있을 것으로 기대한다.

• Imaging Science in Dentistry
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• 제44권2호
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• pp.155-160
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• 2014

Purpose: The purposes of this study were to develop a workstation computer that allowed intraoperative touchless control of diagnostic and surgical images by a surgeon, and to report the preliminary experience with the use of the system in a series of cases in which dental surgery was performed. Materials and Methods: A custom workstation with a new motion sensing input device (Leap Motion) was set up in order to use a natural user interface (NUI) to manipulate the imaging software by hand gestures. The system allowed intraoperative touchless control of the surgical images. Results: For the first time in the literature, an NUI system was used for a pilot study during 11 dental surgery procedures including tooth extractions, dental implant placements, and guided bone regeneration. No complications were reported. The system performed very well and was very useful. Conclusion: The proposed system fulfilled the objective of providing touchless access and control of the system of images and a three-dimensional surgical plan, thus allowing the maintenance of sterile conditions. The interaction between surgical staff, under sterile conditions, and computer equipment has been a key issue. The solution with an NUI with touchless control of the images seems to be closer to an ideal. The cost of the sensor system is quite low; this could facilitate its incorporation into the practice of routine dental surgery. This technology has enormous potential in dental surgery and other healthcare specialties.

• 한국방사선학회논문지
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• 제12권6호
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• pp.793-799
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• 2018

인공지능에 대한 관심이 높아짐에 따라 의료분야에서도 활발하게 인공지능이 연구되고 있다. 현재 국내에서는 엑스선 촬영, 컴퓨터단층촬영(Computer Tomography), 자기공명영상(Magnetic Resonance Imaging) 등의 의료영상장치에 인공지능이 접목되고 있으며 향후 방사선사 없이 환자의 방사선 영상을 획득 할 수 있는 인공지능을 탑재한 의료기기가 발명 될 것으로 예상된다. 본 연구는 엑스선 촬영에 있어서 환자 위치잡이에 대한 자동화에 대해서 초기 연구를 했다. 위치잡이에 대한 평가를 위해 엑스선 장비와 인체 팬텀을 사용했다. 프로그램은 Visual Studio 2010 MFC로 구현했으며 영상은 $1,450{\times}1,814$ 크기로 했다. 픽셀 값을 눈으로 식별 가능한 0 ~ 255 값을 갖는 명암으로 변환하여 모니터에 출력했다. 출력한 영상에 세 픽셀 좌표 값을 통해 각도를 예측하고 각도에 따른 음성안내에 따라 환자가 바른 위치잡이를 하도록 유도하는 절차 알고리즘 프로그램을 개발 했다. 다음 연구에서는 사용자가 좌표의 기준을 인공지능에게 전달하는 것이 아닌 인공지능 스스로 구조물을 파악하여 각도를 계산하는 연구를 진행할 것이다. 향후 위치잡이의 자동화를 통해 촬영부터 위치잡이까지 인공지능이 실시하도록 하는 연구에 도움이 될 것으로 예상된다.

• 의료ㆍ복지 건축 : 한국의료복지건축학회 논문집
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• 제12권2호
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• pp.69-77
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• 2006

Angiography means that a check up to know an abnormal condition in all the blood vessels include from the heart, aortae, cerobrovascular and abdonominal artery to hands and feet. Main examples of this are cerebral angiography, abdominal, liver for urinary anomaly, renovascular angiography, and artery and vein in arms and legs. Angiography uses radial rays or angiography equipment for an image output during interventional procedure and compositive diagnosis. The acts which performed in a projection room have changed drastically. In general, it is performed by using equipment which is attached one or two C-arms and the method of inserting catheter in vein after anesthesia. For this reason, some rooms that consist of angiography room units should be planned not only for expensiveness equipment and facilities also to be germ-free. Nowadays, in the angiography unit case, it is placed independently as the central part of many hospitals. It does not belong to the imaging medical department any more as considering raising filming times and the relation between C.C.U.(coronary care unit) and operation unit. This means the acts performed are diversified and well-organized rooms in support of diagnosis are required. However, it is difficult to plan the angiography room unit due to domestic researches and data on this unit are not enough. Therefore, this study aims at bringing up basic issue for architectural planning of the angiography unit in general hospital.

• 보건행정학회지
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• 제18권4호
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• pp.85-110
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• 2008

In this study, we explore the long-term demand forecasting of high-price medical equipments based on logistic and Bass diffusion model. We analyze the specific pattern of each equipment's diffusion curve by interpreting the parameter estimates of Bass diffusion model. Our findings are as follows. First, ultrasonic imaging system, CT are in the stage of maturity and so, the future demands of them are not too large. Second, medical image processing unit is between growth stage and maturity stage and so, the demand is expected to increase considerably for two or three years. Third, MRI is in the stage of take-off and Mammmography X-ray system is in the stage of maturity but, estimates of the potential number of adopters based on logistic model is considerably different to that based on Bass diffusion model. It means that additional data for these two equipments should be collected and analyzed to obtain the reliable estimates of their demands. Fourth, medical image processing unit have the largest q value. It means that the word-of-mouth effect is important in the diffusion of this equipment. Fifth, for MRI and Ultrasonic system, q/p values have the relatively large value. It means that collective power has an important role in adopting these two equipments.