• Progress in Medical Physics
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• v.19 no.4
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• pp.201-208
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• 2008

Physical evaluations provide the basis for an objective and quantitative analysis of the image quality. Nonetheless, there are limitations in using physical evaluations to judge the utility of the image quality if the observer's subjectivity plays a key role despite its imprecise and variable nature. This study proposes a new method for objective and quantitative evaluation of image quality to compensate for the demerits of both physical and subjective image quality and combine the merits of them. The images of chest phantom were acquired from four digital radiography systems on clinic sites. The physical image quality was derived from an image analysis algorithm in terms of the contrast-to-noise ratio (CNR) of the low-contrast objects in three regions (lung, heart, and diaphragm) of a digital chest phantom radiograph. For image analysis, various image processing techniques were used such as segmentation, and registration, etc. The subjective image quality was assessed by the ability of the human observer to detect low-contrast objects. Fuzzy integral was used to integrate them. The findings of this study showed that the physical evaluation did not agree with the subjective evaluation. The system with the better performance in physical measurement showed the worse result in subjective evaluation compared to the other system. The proposed protocol is an integral evaluation method of image quality, which includes the properties of both physical and subjective measurement. It may be used as a useful tool in image evaluation of various modalities.

• The Korean Journal of Cytopathology
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• v.7 no.1
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• pp.23-30
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• 1996

Chromatin texture, which partly reflects nuclear organization, is evolving as an important parameter indicating cell activation or transformation. In this study, chromatin pattern was evaluated by image analysis of the electron micrographs of follicular and papillary carcinoma cells of the thyroid gland and tested for discrimination of the two neoplasms. Digital grey images were converted from the electron micrographs, nuclear images, excluding nucleolus and intranuclear cytoplasmic inclusions, were obtained by segmentation; grey levels were standardized; and grey level histograms were generated. The histograms in follicular carcinoma showed Gaussian or near-Gaussian distribution and had a single peak, whereas those in papillary carcinoma had two peaks(bimodal), one at the black zone and the other at the white zone. In papillary carcinoma, the peak in the black zone represented an increased amount of heterochromatin particles and that at the white zone represented decreased electron density of euchromatin or nuclear matrix. These results indicate that the nuclei of follicular and papillary carcinoma cells differ in their chromatin pattern and the difference may be due to decondensed chromatin and/or matrix substances.

• Journal of the Korean Society of Radiology
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• v.16 no.4
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• pp.453-462
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• 2022

In this paper, the artificial intelligence (AI) technology used in the medical image analysis field was analyzed through a literature review. Literature searches were conducted on PubMed, ResearchGate, Google and Cochrane Review using the key word. Through literature search, 114 abstracts were searched, and 98 abstracts were reviewed, excluding 16 duplicates. In the reviewed literature, AI is applied in classification, localization, disease detection, disease segmentation, and fit degree of registration images. In machine learning (ML), prior feature extraction and inputting the extracted feature values into the neural network have disappeared. Instead, it appears that the neural network is changing to a deep learning (DL) method with multiple hidden layers. The reason is thought to be that feature extraction is processed in the DL process due to the increase in the amount of memory of the computer, the improvement of the calculation speed, and the construction of big data. In order to apply the analysis of medical images using AI to medical care, the role of physicians is important. Physicians must be able to interpret and analyze the predictions of AI algorithms. Additional medical education and professional development for existing physicians is needed to understand AI. Also, it seems that a revised curriculum for learners in medical school is needed.

• Journal of Biomedical Engineering Research
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• v.22 no.2
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• pp.127-132
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• 2001

의료 영상에서 관심 있는 부위를 3차원으로 재구성하여 보는 것은, 정확한 진단을 위해서 매우 중요하다. 이러한 3차원 재구성을 위해서는 관심 있는 영역의 분할이 필수적인 선행작업이다. 본 논문에서는 관도계 기관의 분할을 위해서 슬라이스 영상의 정보를 이용한 3차원 영역 성장법을 제안한다. 제안된 방법은 2차원 슬라이스 영상에서 영역 성장법에 의해 영역을 확장시키고, 그 이웃한 슬라이스들에 씨앗점을 전달하여 재귀적으로 3차원 체적을 확장하여 영상을 분할한다. 이때, 이웃한 슬라이스간의 영역의 크기의 제약을 이용하여 새나감을 방지한다. 제안된 방법을 기관지의 분할에 적용한 결과, 새나감 없이 뾰족한 가지들까지도 성공적으로 분할했으며, 튜브의 중심 축이 고차원 곡선인 경우에도 성공적으로 분할했다.

• KIPS Transactions on Computer and Communication Systems
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• v.10 no.11
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• pp.305-310
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• 2021

Artificial intelligence technology in the medical field initially focused on analysis and algorithm development, but it is gradually changing to web application development for service as a product. This paper describes a Urinary Stone segmentation model in abdominal CT images and an artificial intelligence web application based on it. To implement this, a model was developed using U-Net, a fully-convolutional network-based model of the end-to-end method proposed for the purpose of image segmentation in the medical imaging field. And for web service development, it was developed based on AWS cloud using a Python-based micro web framework called Flask. Finally, the result predicted by the urolithiasis segmentation model by model serving is shown as the result of performing the AI web application service. We expect that our proposed AI web application service will be utilized for screening test.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.3 no.3
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• pp.597-605
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• 1999

In this paper, we propose a cardioangiography sequence image coding scheme which use a subtraction between initial image and current frame inserted contrast dye. Stable regions are obtained by the multithreshold and meaningful region is extracted by the images with stable region. The image with meaningful region is classified into contour and texture information. Contour information is coded by contour coding. And texture information is approximated by two-dimensional polynomial function and each coefficients is coded. Experimental results confirm that the sequence of cardioangiography are well reconstructed at the low bit rate (0.02∼0.04 bpp) and high compression ratio.

• Journal of the Institute of Electronics Engineers of Korea SC
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• v.44 no.5
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• pp.55-61
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• 2007

In this paper, we propose a three-dimensional(3D) active shape models for medical image segmentation. In order to build a 3D shape model, we need to generate a point distribution model(PDM) and select corresponding landmarks in all the training shapes. The manual determination method, two-dimensional(2D) method, and limited 3D method of landmark correspondences are time-consuming, tedious, and error-prone. In this paper, we generate a 3D statistical shape model using the 3D model generation method of a distance transform and a tetrahedron method for landmarking. After generating the 3D model, we extend the shape model training and gray-level model training of 2D active shape models(ASMs) and we use the integrated modeling process with scale and gray-level models for the appearance profile to represent the local structure. Experimental results are comparable to those of region-based, contour-based methods, and 2D ASMs.

• Progress in Medical Physics
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• v.31 no.3
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• pp.111-123
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• 2020

Deep learning (DL) is a subset of machine learning and artificial intelligence that has a deep neural network with a structure similar to the human neural system and has been trained using big data. DL narrows the gap between data acquisition and meaningful interpretation without explicit programming. It has so far outperformed most classification and regression methods and can automatically learn data representations for specific tasks. The application areas of DL in radiation oncology include classification, semantic segmentation, object detection, image translation and generation, and image captioning. This article tries to understand what is the potential role of DL and what can be more achieved by utilizing it in radiation oncology. With the advances in DL, various studies contributing to the development of radiation oncology were investigated comprehensively. In this article, the radiation treatment process was divided into six consecutive stages as follows: patient assessment, simulation, target and organs-at-risk segmentation, treatment planning, quality assurance, and beam delivery in terms of workflow. Studies using DL were classified and organized according to each radiation treatment process. State-of-the-art studies were identified, and the clinical utilities of those researches were examined. The DL model could provide faster and more accurate solutions to problems faced by oncologists. While the effect of a data-driven approach on improving the quality of care for cancer patients is evidently clear, implementing these methods will require cultural changes at both the professional and institutional levels. We believe this paper will serve as a guide for both clinicians and medical physicists on issues that need to be addressed in time.

• Journal of Biomedical Engineering Research
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• v.19 no.4
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• pp.361-367
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• 1998

We student tow image characteristics, the smoothness and the similarity, which give rise to local and global redundancy in image representation. The smoothness means that the gray level values within a given block vary gradually rather than abruptly. The similarity means that any patterns in an image repeat itself anywhere in the rest of the image. In this sense, we proposed a lossless medical image compression scheme which exploits both types of redundancy. The proposed method segments the image into variable size blocks and encodes them depending on characteristics of the blocks. The proposed compression schemes works better 10~40[%] than other compression scheme such as the Huffman, the arithmetic, the Lempel-Ziv, HINT(Hierachical Interpolation) and the lossless scheme of JPEG with one predictor.

• Journal of Korea Multimedia Society
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• v.13 no.3
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• pp.430-437
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• 2010

It is essential for living donor liver transplantation that surgeon must understand the hepatic vessel structure to improve the success rate of operation. In this paper, we extract the liver boundary without other surrounding structures such as heart, stomach, and spleen using the contrast enhanced MDCT liver image sequence. After that, we extract the major hepatic veins (left, middle, right hepatic vein) with morphological filter after review the basic structure of hepatic vessel which reside in segmented liver image region. The purpose of this study is provide the overall status of transplantation operation with size estimation of resection part which is dissected along with the middle hepatic vein. The method of liver extraction is as follows: firstly, we get rid of background and muscle layer with gray level distribution ratio from sampling process. secondly, the coincident images match with unit mesh image are unified with resulted image using the corse coordinate of liver and body. thirdly, we extract the final liver image after expanding and region filling. Using the segmented liver images, we extract the hepatic vessels with morphological filter and reversed the major hepatic vessels only with a results of ascending order of vessel size. The 3D reconstructed views of hepatic vessel are generated after applying the interpolation to provide the smooth view. These 3D view are used to estimate the dissection line after identify the middle hepatic vein. Finally, the volume of resection region is calculated and we can identify the possibility of successful transplantation operation.