• 대한의용생체공학회:의공학회지
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• 제37권6호
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• pp.209-214
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• 2016

Binaural hearing aids with a voice transmitter have been widely used to enhance sound quality in noisy environment. However, this system has a limitation on sound-source localization. In this study, we investigated automatic directional-gain control method using geomagnetic sensors to provide directional information to binaural hearing aid user. The loudness gains of two hearing aids were differently controlled based on the directional information between a speaker position and a viewing direction of hearing aids user. This relative directional information was measured by two geomagnetic sensors on hearing aids user and a speaker. The results showed that the loudness gains were accurately controlled and could provide directional information based on the cue of interaural level differences.

• IMMUNE NETWORK
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• 제14권4호
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• pp.219-225
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• 2014

We examined the immunogenicity of H-2 class I-restricted and HLA-A2-restricted epitopes through peptide immunization of HLA-A2-transgenic mice that also express mouse H-2 class I molecules. All four of the tested epitopes restricted by H-2 class I robustly elicited T-cell responses, but four of seven epitopes restricted by HLA-A2 did not induce T-cell responses, showing that HLA-A2-restricted peptide epitopes tend to be poorly immunogenic in HLA-A2-transgenic mice. This finding was confirmed in HLA-A2-transgenic mice infected with a recombinant vaccinia virus expressing hepatitis C virus proteins. We examined the precursor frequency of epitope-specific naïve $CD8^+$ T cells in HLA-A2-transgenic and conventional C57BL/6 mice and found that the poor immunogenicity of HLA-A2-restricted peptide epitopes is related to the paucity of naïve $CD8^+$ T-cell precursors in HLA-A2-transgenic mice. These results provide direction for the improvement of mouse models to study epitope repertoires and the immunodominance of human T-cell responses.

• 보건교육건강증진학회지
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• 제7권2호
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• pp.1-14
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• 1990

This papaer discusses the recent tendencies of health approach in the developed countries and suggests the strategy of health approach in order to cope with the changing environmental conditions of Korea in 2000's. In 2000's, Korea will have the environmental conditions and health problems similar to those of the developed countries at present. The American and European developed countries have shown the integrative approach trend by the interdisciplinary cooperation based on the holistic health conception, for example, as in the behavioral medicine, with the active drive of the medical self care movement and the national health preactice movement. The basic solution to the 2000's main health problems such as high morbidity of chronic diseases and high medical expenditure is to decrease the health need through the health promotion, disease prevention and early. ditection and early treatment of disease. The above actions need to induce the public to change their health behavior in the desirable direction through the national health practice movement and the health self care movement. The succeed of the movements depends upon how to use effectively the mass media, health and administrative organizations, schools, industrial and medical insurance organizations with the strong government support of health and preventive policies and programs.

• Applied Microscopy
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• 제26권2호
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• pp.177-195
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• 1996

Fine structure of the processes of intramembranous ossification and endochondral ossification at the tip of the distal phalanx of human fetuses was studied by electron microscopy. In 50 mm fetus, intramembranous ossification of the tip of cartilaginous phalanx was first noted. The osteoblasts of the perichondral zone of tip of cartilaginous phalanx started to lay down a thick membranous bony lamella. Most of the hypertrophied chondrocytes in the marginal parts of tip of the distal phalanx remained viable after being embeded in mineralized cartilaginous septa. The tuberosity of the distal phalanx was formed by membranous bony trabeculae on the exterior of the subperiosteal cap at 80 mm fetus. At this stage endochondral ossification was first observed in distal extremity of the distal phalanx. The maority of hypertrophied chondrocytes in the center of distal extremity appeared to be disintegrating. Resorption of calcified matrix was undertaken by perivascular cells and chondroclasts. From the periosteum, zone of calcification, vascular sprouts expanded within a recently opened lacunae, and the invading osteoblasts laid down osteoid and bone. After 120 mm fetus, endochondral and subperiosteal ossification proceeded in only one direction, just proximally. These findings demonstrate that intramembranous ossification, calcification, and endochondral ossification start at tip of the distal phalanx instead of at the center of the shaft, as was the case in other long bones.

• 한국응급구조학회지
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• 제17권3호
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• pp.101-113
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• 2013

Purpose: The purpose of this study was to provide an appropriate direction for effective field practice program by analyzing the influencing factors on satisfaction of field instructor in ambulance ride practice of paramedic students in Korea. Methods: The questionnaires were filled out by 204 paramedic students from July 22 to September 13, 2013. The collected data were analyzed with SPSS WIN 19.0 program. Results: The stepwise multiple regression analysis revealed that the most powerful predictor of satisfaction of field instructor was sincerity of directions. A combination of sincerity of directions (38.2%), achievement(15.4%), improvement of knowledge(3.9%) 4-week field practice(3.0%), 2 week field practice(1.6%), 4 grade(1.8%) pre-expectation of field practice(1.8%) accounted for 65.6% of the variance in paramedic students. Conclusion: We proposed the effective field practice program as well as sincerity of directions of field instructors. It is necessary to discuss before ambulance ride practice within the faculty and the field instructors.

• 한국실내디자인학회논문집
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• 제24권3호
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• pp.165-175
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• 2015

Korean medical welfare facilities for the elderly provide the conveniences to care geriatric illness such as dementia and stroke. The medical welfare facility categorizes elderly care facilities, nursing homes, and geriatrics hospitals based on the Korean welfare of the aged act. The government makes an effort to secure feed rate and finances of medical welfare facilities. However, the qualitative improvement of facilities is inadequate. The purpose of this study is to analyze the conditions and problems of existing facilities using an environmental evaluation and to discuss the improvement direction related to the daycare centers for the elderly. The method of this study is literature review and field survey. Firstly, we analyzed the previous studies to develop the tool, evaluating the environment of day care centers for the old. Secondly, the items of environmental evaluation are deduced. Thirdly, we select the facilities to conduct field survey and analyze the results of field survey. Lastly, We discussed the problems and improvement directions through the results. It is judged that this study is an useful as the basic guideline to strengthen the minimum legal standards of day care center for the elderly due to the suggestion of insufficient environmental evaluation items.

• 한국정보통신학회논문지
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• 제3권4호
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• pp.715-722
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• 1999

본 연구는 노인복지정책을 위한 정보통신시스템을 어떠한 방향으로 개발해야 하는지를 분석하기 위해 연구하였으며, 연구방법으로는 문헌자료와 현장방문 면담조사를 병행하여 실시하였다. 문헌자료는 주로 이론적 배경을 중심으로 연구하였으며, 면담조사는 1999년 9월 15일에서 16일 양일간에 무작위적 방법에 의해 노인들을 면담하여 노인들이 지금 필요로 하는 것이 무엇인지를 파악하는데 이용하였다. 면담결과를 분석해 보면, 노인들이 가장 많이 요구하는 것이 경제적 요구 의료요구 주택요구ㆍ문화요구ㆍ교통요구ㆍ교육요구 순으로 나타내고 있다. 노인들의 요구에 의한 정보통신시스템의 개발은 경제적 요구에는 재택근무시스템ㆍ홈쇼핑시스템ㆍ홈뱅킹시스템이 필요하며, 의료요구에는 의료지원시스템ㆍ의료정보시스템ㆍ원격의료지원시스템, 주택요구에는 가정자동화시스템ㆍ인터넷시스템, 문화요구에는 이벤트정보시스템ㆍ여가정보시스템, 교통요구에는 자동교통지리시스템ㆍ자동운전시스템, 교육요구에는 원격교육시스템ㆍ지식학습지원시스템 등의 개발이 필요하다.

• 대한한의학방제학회지
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• 제21권2호
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• pp.29-43
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• 2013

Objectives : The aim of this study is reviewing the past legal definition and regulations, to provide basis for the future desirable direction of Korean herbal pharmaceutical industry and national herbal drug policies. Methods : We reviewed how concept of herbal medicinal preparation has been utilized and changed along with various national laws and regulations. And this study also reviewed problems related herbal medicinal preparation policies. Results : Since 1990s, especially inauguration of Korea Food & Drug Administration (KFDA) at 1998, the concept of crude drug preparation has constantly expanded and distorted the scope of herbal medicinal preparations. This resulted in decline of herbal medicinal preparation industry. Conclusions : It means policies related herbal medicinal preparation which was driven steadily during this decade have lost their consistency. Also, it restricted the various medical options which can guarantee people's health rights.