• Journal of Microbiology and Biotechnology
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• 제30권2호
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• pp.287-295
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• 2020

The differences between luminal microbiota (LM) and mucosal microbiota (MAM) were little known, especially in duodenum. In this study, LM and MAM in colon and duodenum of mice were investigated through 16S rRNA high-throughput sequencing. The lowest bacterial diversity and evenness were observed in duodenal LM (D_LM), followed by duodenal MAM (D_MAM). Meanwhile, the bacterial diversity and evenness were obviously increased in D_MAM than these in D_LM, while no significant difference was observed between colonic MAM (C_MAM) and colonic LM (C_LM). PCoA analysis also showed that bacterial communities of LM and MAM in duodenum were completely separated, while these in colon overlapped partly. The ratio of Firmicutes to Bacteroidetes (F/B) in D_MAM was significantly higher than that in D_LM. Lactobacillus was largely enriched and was the characteristic bacteria in D_LM. The characteristic bacteria in D_MAM were Turicibacter, Parasutterella, Marvinbryantia and Bifidobacterium, while in C_LM they were Ruminiclostridium_6, Ruminiclostridium_9, Ruminococcaceae_UCG_007 and Lachnospiraceae_UCG_010, and in C_MAM they were Lachnospiraceae_NK4A136, Mucispirillum, Alistipes, Ruminiclostridium and Odoribacter. The networks showed that more interactions existed in colonic microbiota (24 nodes and 74 edges) than in duodenal microbiota (17 nodes and 29 edges). The 16S rDNA function prediction results indicated that bigger differences of function exist between LM and MAM in duodenum than these in colon. In conclusion, microbiota from intestinal luminal content and mucosa were different both in colon and in duodenum, and bacteria in colon interacted with each other much more closely than those in duodenum.

• 대한수의사회지
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• 제9권3호
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• pp.62-66
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• 1965

Gross and histopathologic studies on a Korean-breed, 2-year-old, male dog revealed the ma1ignant lymphoma with the characteristic features of histiocytic type in the subcutis, intercostal muscle, heart, trachea, lung, spleen, liver, kidney, penis and panc

• 대한디지털의료영상학회논문지
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• 제8권1호
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• pp.45-49
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• 2006

• 대한한의학원전학회지
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• 제30권1호
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• pp.1-15
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• 2017

Objectives : Ge Songping(戈頌平) was a medical doctor in Qing Dynasty during the late $19^{th}$ century who annotated the original texts of four medical classics and wrote Suwenzhigui (素問指歸), Shanghanzhigui(傷寒指歸), Jinkuizhigui(金匱指歸), and Shennongbencaojingzhigui (神農本草經指歸). This paper's objective is to compile information about his writings, and shed a light on the unique characteristic of his scholarly works. Methods : Information regarding Ge Songping's life has been gathered through existing research papers and the sources revealed in the introduction. His works were divided into different formal characters as listed in part of the introduction and in the table of contents. Contents related to Yinyang(陰陽) found in Suwenzhigui were studied in order to discover his unique scholastic character. After selecting and analyzing three texts related to Yinyang, some characteristic terms and emphasized contents were studied. Results : The review yielded knowledge about Ge Songping's life, the times of his publications, the meanings of the names of his books, and basic information abou them. In terms of his scholarstic works, he used the ideas he gained from Shanghanlun(傷寒論) to form his medical theory, and used this to write annotations for four types of medical classics. The features of his theory of Yinyang can be divided into four categories. First, he coined the term Qiye(氣液) to bring contrast between yinyang as yinye(陰液) and yangqi(陽氣). Second, he shaped the temporal and spatial structure of the circulation of yinyang based on Shierdizhi(十二地支). Third, he explained the relationship between yin and yang while mainly focused on yangqi. Fourth, he explained the physiology and pathology mechanisms while focused on the circulation of ascending and descending and the idea of mutual beneficiary.

• 대한한의학원전학회지
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• 제29권2호
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• pp.13-29
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• 2016

Objectives : The purpose of this study is to investigate the concept of the Chukbu(尺膚) diagnosis in Huangdineijing(黃帝內經) and explain the characteristic of Chukbu(尺膚) diagnosis and causes of its clinical applicational decline. It will help the application of the Chukbu(尺膚) diagnosis to clinical treatment. Methods : The Sikuquanshu(四庫全書) database and Traditional Chinese Medical(TCM) books web database were used. The related contents of the Chukbu(尺膚) diagnosis in Huangdineijing (黃帝內經) and its annotation books were analyzed. The mentions on the Chukbu(尺膚) diagnosis in other medical books were examined. Results & Conclusions : The Chukbu(尺膚) diagnosis is important in the diagnostic system of the Huangdineijing(黃帝內經). The Chukbu(尺膚) diagnosis is composed of inspection and palpation. Its characteristic is something different compared to that of the Chongumaek(寸口脈) diagnosis; it relatively diagnoses condition of exterior disease(表病). The causes of its clinical applicational decline are relative inconvenience, limits of feudal society, and development of Zangfubianzheng(臟腑辨證) in that era.

• Molecules and Cells
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• 제37권1호
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• pp.17-23
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• 2014

We already had reported that Bcl-w promotes invasion or migration in gastric cancer cells and glioblastoma multiforme (GBM) by activating matrix metalloproteinase-2 (MMP-2) via specificity protein 1 (Sp1) or ${\beta}$-cateinin, respectively. High expression of Bcl-w also has been reported in GBM which is the most common malignant brain tumor and exhibits aggressive and invasive behavior. These reports propose that Bcl-w-induced signaling is strongly associated with aggressive characteristic of GBM. We demonstrated that Sp1 protein or mRNA expression is induced by Bcl-w using Western blotting or RT-PCR, respectively, and markedly elevated in high-grade glioma specimens compared with low-grade glioma tissues using tissue array. However, relationship between Bcl-w-related signaling and aggressive characteristic of GBM is poorly characterized. This study suggested that Bcl-w-induced Sp1 activation promoted expression of glioma stem-like cell markers, such as Musashi, Nanog, Oct4 and sox-2, as well as neurosphere formation and invasiveness, using western blotting, neurosphere formation assay, or invasion assay, culminating in their aggressive behavior. Therefore, Bcl-w-induced Sp1 activation is proposed as a putative marker for aggressiveness of GBM.

• 한국의사학회지
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• 제29권1호
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• pp.1-9
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• 2016

The word Euisaeng (醫生) is shorthand the Euihaksaengdo (medical cadets), that means has been changed according to the times. Throughout the Goryeo dynasty, Euisaeng was not mean medical student, but also primary healthcare. Existing research on Euisaeng of Joseon dynasty has been grouped together, despite the identity and characteristic differences between the central and local Euisaeng. The authors have separated the two, and a review of the literature focuses on local Euisaeng. The authors found the following facts in this study. First, status of Oebang-euisaeng (local medical cadets) was declined in the latter than in the early Joseon. Second, Oebang-euisaeng of the late Joseon was Layered Hyang'ri. Third, The local medical cadets was important, the role of primary healthcare. On the other hand, The central medical cadets was important, the role of a student learning medicine.

• 한국광학회:학술대회논문집
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• 한국광학회 2002년도 하계학술발표회
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• pp.148-149
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• 2002

중적외선 분광학(mid-IR spectrocopy) 에서는 2.5～15 $\mu\textrm{m}$ 의 파장을 갖는 적외선을 시료에 조사하여 absorption spectrum 을 측정하는데 이 대역은 주로 분자들의 fundamental band 가 나타나는 영역으로 각 분자의 characteristic absorption band 가 비교적 깨끗하게 분리되어 있어 특정 compound 의 존재 유무를 확인하는데 쓰여 왔다. 그러나 보통의 경우에 시료에는 한 가지 화합물만이 존재하는 것이 아니고 여러 가지 화합물이 섞여 있는 경우가 많다. (중략)

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2006년도 추계학술대회 논문집
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• pp.563-564
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• 2006

• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 1999년도 Japanese Journal of Medical Physics
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• pp.49-51
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• 1999