• Asian Pacific Journal of Cancer Prevention
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• 제13권11호
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• pp.5627-5632
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• 2012

Background: The aim of the study was to determine the prevalence of shisha smoking and associated factors among medical students in Malaysia. Materials and Methods: A cross-sectional study was conducted at the Management and Science University from December 2011 until March 2012. The questionnaire consisted of five sections including socio-demographic, social environment, knowledge about shisha, psychosocial factors, and personal shisha smoking behavior. Obtained data were analyzed using Statistical Package for the Social Sciences (SPSS 13). T-test was used to determine the relationships between shisha smoking and socio-demographic characteristic. Results: A total number of 300 medical students participated in this study. Mean age was $22.5{\pm}2.5$ years. The majority were female, Malay, single, from urban areas (67%, 54%, 97%, 73%; respectively). The prevalence of shisha smoking among medical students was found to be 20%. The study revealed that many students believed that shisha does not contains nicotine, carbon monoxide, does not lead to lung cancer, dental problems and does not lead to cardiovascular diseases (25%, 20.7%, 22.3%, 29%, 26.7%; respectively). Age and sex were found to be significantly associated with smoking shisha status among medical students (p=0.029, p<0.001; respectively). Furthermore, having parents, siblings and friends smokers of shisha were found to be significantly associated with shisha smoking status (p<0.001, p<0.001, p<0.001; respectively). Furthermore, family problems, problems with friends, financial problems and university life were found to significantly associated with shisha smoking status among medical students (p<0.001, p=0.002, p<0.001, p=0.002; respectively). Conclusions: There is a high prevalence of shisha smoking and a poor knowledge about its impact on health among medical students. More attention is needed to focus on medical education in this regard. The policies that are currently employed in order to reduce the cigarettes smoking should be applied to shisha smoking and shisha products.

• Journal of Genetic Medicine
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• 제16권2호
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• pp.49-54
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• 2019

Purpose: Potocki-Lupski syndrome (PTLS), is a recently identified, rare genomic disorder. The patients are affected by infantile hypotonia, poor growth and developmental delay. Facial dysmorphism may not be obvious in some patients. PTLS is associated with microduplication at chromosome 17p11.2. In the current study, three Korean patients are reported with their clinical and genetic features. Materials and Methods: The clinical findings of each patient were reviewed. Karyotyping and multiplex ligation-dependent probe amplification (MLPA) analyses were done for genetic diagnoses. Results: All the patients did not have the characteristic dysmorphic features, such as broad forehead, triangular face, asymmetric smile and palpebral fissures. On the other hand, all three patients were affected by variable degree of developmental delay, poor oral intake, failure to thrive, and language development disorders. Chromosome 17p11.2 duplication was identified by conventional karyotyping analysis only in one patient, whereas the other confirmed by MLPA analyses. Conclusion: Delayed development was mostly commonly observed in our patients without distinct dysmorphic facial features. In this respect, genomic screening in patients with developmental delay would identify more cases with PTLS to understand their long-term clinical courses with the development of adequate psychological and rehabilitation education program.

• Korean Journal of Oriental Medicine
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• 제3권1호
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• pp.17-40
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• 1997

${\ulcorner}$Classified Collection of Medical Prescriptions${\lrcorner}$(${\ulcorner}$醫方類聚${\lrcorner}$ is a medical book which classifies and edits the existing books. First of all, it is not until finishing the study of reference books that we can study the ${\ulcorner}$Classified Collection of Medical Prescriptions${\lrcorner}$ in earnest. We did not take traditional non-systematic methods to study the reference books of ${\ulcorner}$Classified Collection of Medical Prescriptions${\lrcorner}$ systematically. We investigated the title of 'reference book's name' as a reference book and did not investigate re-reference books. The number of reference books are one hundred forty-two volumes. Most of the reference books are medical books; some books are about Taoism and Buddhism. The title of the reference books are given a name by various methods. But these methods have a lot of problems. First, the same title book misapply an alias, the original text name and an abbreviated name. Second, a chapter name misapplies reference books. Third, reference books misapplies a chapter name. Forth, the writer and book name misapplies reference books and so on. From quotation collection about ${\ulcorner}$Classified Collection of Medical Prescriptions${\lrcorner}$'s characteristic point fellows below in three kinds. First, it emphasizes medical therapy. Second, most of Song(宋) period, Geum Yuan(金 元) period of China reference books take place in here. During this period it had accepted studying theory from clinical accumulation and the result of re-clinical studies reception based on theory research, and also had accepted Geum Yuan's expansive theory. Third, by adding technical books of a professional assortment, it has raised its profession of division.

• Clinical and Experimental Reproductive Medicine
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• 제47권1호
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• pp.61-67
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• 2020

Objective: In this study, specimens from testicular biopsies of men with nonobstructive azoospermia (NOA) were used to investigate whether RNF8 gene could serve as a biomarker to predict the presence of sperm in these patients. Methods: Testicular biopsy specimens from 47 patients were classified according to the presence of sperm (positive vs. negative groups) and investigated for the expression of RNF8. The level of RNF8 gene expression in the testes was compared between these groups using reverse-transcription polymerase chain reaction. Results: The expression level of RNF8 was significantly higher in testicular samples from the positive group than in those from the negative group. Moreover, the area under the curve of RNF8 expression for the entire study population was 0.84, showing the discriminatory power of RNF8 expression in differentiating between the positive and negative groups of men with NOA. A receiver operating characteristic curve analysis showed that RNF8 expression had a sensitivity of 81% and a specificity of 84%, with a cutoff level of 1.76. Conclusion: This study points out a significant association between the expression of RNF8 and the presence of sperm in NOA patients, which suggests that quantified RNF8 expression in testicular biopsy samples may be a valuable biomarker for predicting the presence of spermatozoa in biopsy samples.

• Journal of The Korean Society of Emergency Medicine
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• 제29권5호
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• pp.399-407
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• 2018

Objective: Regionalization is one of the principal subjects for the advancement of rural emergency medical service systems in South Korea. This study shows the characteristics of interhospital transfer and status of the incidence of three major emergency disorders (acute myocardial infarction [AMI], acute stroke, and severe trauma) in one local province. Methods: A retrospective study was conducted for patients with three major emergency disorders who visited emergency medical facilities in one local province from January 2013 to December 2015, on the basis of the National Emergency Department Information System (NEDIS) data. Results: The incidence of three major emergency disorders had increased annually. Patients with each of these disorders tended to choose distinguishing methods of visiting emergency medical facilities. AMI patients tended to visited emergency medical facilities using private cars or on foot, while severe trauma patients usually visited by 119 ambulance, and acute stroke patients used 119 ambulance and private car in similar amounts. Overall, 65% of AMI patients were treated in intraregional medical facilities, but about 70% of acute stoke and severe trauma patients were transferred outside of the region. Conclusion: Because each of these disorders has an individual characteristic, it is difficult to expect a solution for the problems associated with emergency disorders just by assuring the availability of medical resources. Based on regionalization, a policy to provide the optimal treatment for those emergency disorders should be developed by planning public medical service systems based on the individual characteristics of emergency disorders, the standardized transfer plans of emergency patients and the assurance for mobilization and sharing of confined medical resources.

• The Journal of Korean Medical History
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• 제27권2호
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• pp.39-51
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• 2014

Objectives : The term ByunJeung is usually used to represent the characteristic of Korean Medicine. However the meaning of ByunJeung has not been consistent. After the 1980s when Traditional Chinese Medicine was introduced into Korea, the meaning of ByunJeung in Korea became diverse. In this paper, we aimed to research how the meaning of ByunJeung has been varied. Methods : We used four major journal database in Korea to search articles related to ByunJeung. Using the terms such as "변증" and "辨證", which mean ByungJeung in Korean and Chinese, we collected 500 articles in total. Among them, we chose only 61 articles selectively which mainly focused on the meaning of ByunJeung. We categorized those according to the specific meaning of ByunJeung which each article used, and qualitatively analyzed those articles. Results : Articles related to ByunJeung were categorized into three different groups. The first group was for the articles which dealt with changing meanings of ByunJeung. The second group was for the articles which focused on the modernized meaning of ByunJeung. The third group was for the articles which was on the traditional meaning of ByunJeung. Conclusions : The term ByunJeung holds a key concept in the current field of Korean medicine. Nevertheless, since the meaning of ByunJeung has been diverse, it often caused confusion among the people who used the term ByunJeung. Therefore we need to clarify the exact meaning when we intend to use the term. Also there should be a further discussion on the meaning of ByunJeung in the field of Korean medicine to facilitate better understanding on the characteristic of Korean medicine.

• Progress in Medical Physics
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• 제28권4호
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• pp.164-170
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• 2017

One of the methods to consider the effect of respiratory motion of a tumor target in radiotherapy is to establish a treatment plan with the internal target volume (ITV) created based on an accurate analysis of the target motion displacement. When this method is applied to intensity modulated radiotherapy (IMRT), it is expected to yield a different treatment dose distribution under the motion condition according to the IMRT method. In this study, we prepared ITV-based IMRT plans with conventional IMRT using fixed gantry angle beams, RapidArc using volumetric modulated arc therapy, and tomotherapy using helical therapy. Then, the variation in dose distribution caused by the target motion was analyzed by the dose measurement in the actual motion condition. A delivery quality assurance plan was prepared for the established IMRT plan and the dose distribution in the actual motion condition was measured and analyzed using a two-dimensional diode detector placed on a moving phantom capable of simulating breathing movements. The dose measurement was performed considering only a uniform target shape and motion in the superior-inferior (SI) direction. In this condition, it was confirmed that the error of the dose distribution due to the target motion is minimum in tomotherapy. This is thought to be due to the characteristic of tomotherapy that treats the target sequentially by dividing it into several slices. When the target shape is uniform and the main target motion direction is SI, it is considered that tomotherapy for the ITV-based IMRT method has a characteristic which can reduce the dose difference compared with the plan dose under the target motion condition.

• Journal of radiological science and technology
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• 제32권2호
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• pp.147-151
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• 2009

In general, the discrete confidence judgments that use five-step assessment method have been used to assess the medical images by ROC. TPF or FPF can be computed easily with this independent reading test. However, during experiments, it happens frequently that adequate distribution for observers is required to smoothly estimate the ROC curve. In addition, data becomes invalid for distribution of the created categories. To solve such problems or to apply the ROC interpretation to data that is not obtained from the experimental observation, the continuous confidence judgements (CCJ) has been proposed, which implements ROC interpretation using continuously-distributed experimental results without category classification has been used. As the use of CCJ to assess medical images was barely reported in Korea, we applied it to the assessment of chest digital images in this study. The results showed that a smooth ROC curve was obtained conveniently by the commercialized program and the characteristic value was measured easily. Therefore, it is recommended that this method can be applied to the assessment of digital medical images.

• Proceedings of the Korean Society of Medical Physics Conference
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• 한국의학물리학회 2002년도 Proceedings
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• pp.396-399
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• 2002

Intense quasi-monochromatic x-ray irradiation from the linear plasma target is described. The plasma x-ray generator employs a high-voltage power supply, a low-impedance coaxial transmission line, a high-voltage condenser with a capacity of about 200 nF, a turbo-molecular pump, a thyristor pulse generator as a trigger device, and a flash x-ray tube. The high-voltage main condenser is charged up to 55 kV by the power supply, and the electric charges in the condenser are discharged to the tube after triggering the cathode electrode. The x-ray tube is of a demountable triode that is connected to the turbo molecular pump with a pressure of approximately 1 mPa. As electron flows from the cathode electrode are roughly converged to the molybdenum target by the electric field in the tube, the weakly ionized plasma, which consists of metal ions and electrons, forms by the target evaporating. In the present work, the peak tube voltage was almost equal to the initial charging voltage of the main condenser, and the peak current was about 20 kA with a charging voltage of 55 kV. When the charging voltage was increased, the linear plasma x-ray source grew, and the characteristic x-ray intensities of K-series lines increased. The quite sharp lines such as hard x-ray lasers were clearly observed. The quasi-monochromatic radiography was performed by a new film-less computed radiography system.

• The Journal of Pediatrics of Korean Medicine
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• 제32권4호
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• pp.51-62
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• 2018

Objectives The purpose of this study is to analyze the characteristic of pediatric patients who visited oriental medical hospital for growth treatment. Methods The study was conducted with 130 pediatric patients who visited ${\bigcirc}{\bigcirc}$ Korean medicine hospital from January 2016 to August 2017. The patient's data was classified by sex, age, pattern identification and diseases. The classified data was analyzed to find the correlations and characteristics among variables. Results There were 50.8% of boys and 49.2% of girls. 6.2% of the total patients were in 'early childhood', 50.8% were in 'late childhood' and 43.1% were in 'puberty' stage. In terms of pattern identification, 44.6% of the total patients were 'Spleen-lung Qi Deficiency', 53.8% were 'Lung-kidney Yin Deficiency' and 1.5% were 'Weakness of Heart and gallbladder'. 44.3% of the patients had various diseases including rhinitis (77.6% of 120.7%). Height percentile of the children with using the Growth chart of 2017 was lower than using the Growth chart of 2007. Predicted height based on the child's bone-age were higher than the predicted height based on the parental height, although both of the precited factors were correlated to the current child's height. Conclusions This study showed the characteristic of the pediatric patients who visited oriental medical hospital for growth treatment. It helps to determine prognosis and treatment, and to explain treatment measures.