• Parasites, Hosts and Diseases
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• 제46권4호
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• pp.261-263
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• 2008

Strongyloides stercoralis is a human intestinal parasite which may lead to complicated strongyloidiasis in immunocompromised. Here, a case of complicated strongyloidiasis in a patient with chronic lymphocytic leukemia is reported. Presence of numerous S. stercoralis larvae in feces and sputum confirmed the diagnosis of hyperinfection syndrome in this patient. Following recovery of filariform larvae from agar plate culture of the stool, the isolate was characterized for the ITS1 region of ribosomal DNA gene by nested-PCR and sequencing. Albendazole therapy did not have cure effects; and just at the beginning of taking ivermectin, the patient died. The most important clue to prevent such fatal consequences is early diagnosis and proper treatment.

• 전자통신동향분석
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• 제35권7호
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• pp.56-66
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• 2020

As the development of artificial intelligence (AI) technology spreads to various industrial sectors, diversity in AI utilization rapidly increases, creating rich user experience. In addition, AI is required to solve various social problems through the use of public data. The spread of AI utilization across all sectors will continue, covering such industrial and public demands. This article examines the domestic and international trends in AI utilization technologies and establishes the direction of research and development (R&D), which is highly consistent with Korea's AI policy. ETRI, which leads AI's national R&D, has used its experience to establish AI R&D implementation strategies as well as technology roadmaps for the utilization of AI to improve individual quality of life, continuous growth in society, industrial innovation, and the solutions to public societal problems. In addition, it has derived tasks and implementation strategies for developing AI utilization technologies in 10 major areas including medical services.

• Parasites, Hosts and Diseases
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• 제50권2호
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• pp.99-102
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• 2012

Serum samples, 100 in the total number, were collected from different laboratories in Tehran, Iran and tested for anti-Toxoplasma specific IgG and IgM antibodies using indirect immunofluorescent antibody test (IFAT). Using the IgG (chronic) and IgM (acute) positive samples, the IgG avidity test was performed by ELISA in duplicate rows of 96-well microtiter plates. One row was washed with 6 M urea and the other with PBS (pH 7.2), then the avidity index (AI) was calculated. Sixteen out of 18 (88.9%) sera with acute toxoplasmosis showed low avidity levels ($AI{\leq}50$), and 76 out of 82 (92.7%) sera in chronic phase of infection showed high avidity index (AI>60). Six sera had borderline ranges of AI. The results showed that the IgG avidity test by ELISA could distinguish the acute and chronic stages of toxoplasmosis in humans.

• 한국정보처리학회:학술대회논문집
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• 한국정보처리학회 2023년도 추계학술발표대회
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• pp.608-610
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• 2023

의료 분야에서 AI 모델의 활용이 증가하고 있지만, 모델의 예측 불확실성을 정확하게 평가하고 표현하는 것이 중요하다. 본 연구는 이러한 문제를 해결하기 위해 AI-driven 방식을 제안하며, 특히 의료 영상 변환 모델에 대한 불확실성 표현과 데이터 한계 극복 방법론을 제안한다. 제안된 AI-driven 안저영상 변환 모델은 기존 GAN과는 다르게 구조가 이루어져 있으며, 신뢰도가 낮은 영역을 구분하고 시각화하여 표현할 수 있다. 실험 결과, 제안된 방법은 기존 모델과 비교하여 영상 변환 성능이 크게 향상되었으며, 불확실성에 대한 정확도 평가에서도 AI-driven 방식이 높은 성능을 보인다. 결론적으로, 본 연구는 AI-driven 방식을 통해 의료 AI에서의 불확실성 표현의 가능성을 확인하였으며, 이 방식이 데이터의 한계와 불확실성을 극복할 수 있을 것으로 기대된다.

• Korean Journal of Radiology
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• 제23권10호
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• pp.1009-1018
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• 2022

Objective: This study aimed to investigate the feasibility of using artificial intelligence (AI) to identify normal chest radiography (CXR) from the worklist of radiologists in a health-screening environment. Materials and Methods: This retrospective simulation study was conducted using the CXRs of 5887 adults (mean age ± standard deviation, 55.4 ± 11.8 years; male, 4329) from three health screening centers in South Korea using a commercial AI (Lunit INSIGHT CXR3, version 3.5.8.8). Three board-certified thoracic radiologists reviewed CXR images for referable thoracic abnormalities and grouped the images into those with visible referable abnormalities (identified as abnormal by at least one reader) and those with clearly visible referable abnormalities (identified as abnormal by at least two readers). With AI-based simulated exclusion of normal CXR images, the percentages of normal images sorted and abnormal images erroneously removed were analyzed. Additionally, in a random subsample of 480 patients, the ability to identify visible referable abnormalities was compared among AI-unassisted reading (i.e., all images read by human readers without AI), AI-assisted reading (i.e., all images read by human readers with AI assistance as concurrent readers), and reading with AI triage (i.e., human reading of only those rendered abnormal by AI). Results: Of 5887 CXR images, 405 (6.9%) and 227 (3.9%) contained visible and clearly visible abnormalities, respectively. With AI-based triage, 42.9% (2354/5482) of normal CXR images were removed at the cost of erroneous removal of 3.5% (14/405) and 1.8% (4/227) of CXR images with visible and clearly visible abnormalities, respectively. In the diagnostic performance study, AI triage removed 41.6% (188/452) of normal images from the worklist without missing visible abnormalities and increased the specificity for some readers without decreasing sensitivity. Conclusion: This study suggests the feasibility of sorting and removing normal CXRs using AI with a tailored cut-off to increase efficiency and reduce the workload of radiologists.

• 한국멀티미디어학회논문지
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• 제25권2호
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• pp.345-352
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• 2022

Conducting AI-based fusion business due to the increment of ICT fusion medical device has been expanded. In addition, AI-based medical devices help change existing medical system on treatment into the paradigm of customized treatment such as preliminary diagnosis and prevention. It will be generally promoted to the change of medical device industry. Although the current demand forecasting of medical biotechnology commercialization is based on the method of Delphi and AHP, there is a problem that it is difficult to have a generalization due to fluctuation results according to a pool of participants. Therefore, the purpose of the paper is to predict demand forecasting for identifying promising technology based on building up big data in medical biotechnology. The development method is to employ candidate technologies of keywords extracted from SCOPUS and to use word2vec for drawing analysis indicator, technological distance similarity, and recommended technological similarity of top-level items in order to achieve a reasonable result. In addition, the method builds up academic big data for 5 years (2016-2020) in order to commercialize technology excavation on demand perspective. Lastly, the paper employs global data studies in order to develop domestic and international demand for technology excavation in the medical biotechnology field.

• 대한의용생체공학회:의공학회지
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• 제43권4호
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• pp.259-270
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• 2022

Artificial intelligence (AI) has been studied in various fields of medical imaging. Currently, top-notch deep learning (DL) techniques have led to high diagnostic accuracy and fast computation. However, they are rarely used in real clinical practices because of a lack of reliability concerning their results. Most DL models can achieve high performance by extracting features from large volumes of data. However, increasing model complexity and nonlinearity turn such models into black boxes that are seldom accessible, interpretable, and transparent. As a result, scientific interest in the field of explainable artificial intelligence (XAI) is gradually emerging. This study aims to review diverse XAI approaches currently exploited in medical imaging. We identify the concepts of the methods, introduce studies applying them to imaging modalities such as computational tomography (CT), magnetic resonance imaging (MRI), and endoscopy, and lastly discuss limitations and challenges faced by XAI for future studies.

• 스마트미디어저널
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• 제9권3호
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• pp.59-70
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• 2020

This paper presents a fully automatic tool to recognize the liver region from CT images based on a deep learning model, namely Multiple Filter U-net, MFUnet. The advantages of both U-net and Multiple Filters were utilized to construct an autoencoder model, called MFUnet for segmenting the liver region from computed tomograph. The MFUnet architecture includes the autoencoding model which is used for regenerating the liver region, the backbone model for extracting features which is trained on ImageNet, and the predicting model used for liver segmentation. The LiTS dataset and Chaos dataset were used for the evaluation of our research. This result shows that the integration of Multiple Filter to U-net improves the performance of liver segmentation and it opens up many research directions in medical imaging processing field.

• 한국방사선학회논문지
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• 제17권6호
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• pp.939-945
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• 2023

본 연구는 영상의학 분야에서 인공지능(AI) 기술 기반의 판독 보조 시스템의 'Time Behavior(시간반응성)' 속성을 측정하여 '성능 효율성'을 분석하였다. 의료 영상의 증가와 영상의학 전문의 수의 한계로 인해 인공지능(AI) 기술 기반의 솔루션이 증가하고 있으며, 관련된 연구가 많이 수행되고 있다. 하지만 대부분의 선행 연구가 인공지능의 진단 정확도에 초점을 맞췄다면, 본 연구는 Time Behavior의 중요성을 강조하여 수행하였다. 50개의 흉부 엑스레이 PA 이미지를 사용하여 측정한 결과, 평균 15.24초 만에 영상을 처리하여 높은 일관성과 안정성을 보여주었고, 이 처리 속도는 유명 글로벌 AI 플랫폼과 동등한 수준으로 영상의학과 워크플로우 효율성 부분에 크게 개선될 수 있는 가능성을 제시하였다. 앞으로 인공지능 기술이 영상의학 분야에서 큰 역할을 담당하여, 전반적인 의료 품질 향상과 효율성을 개선하는 데 도움이 될 것으로 기대한다.

• 한국인공지능학회지
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• 제11권4호
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• pp.9-13
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• 2023

In this study, we explored the potential of integrating interactive AI callbot technology into the medical consultation domain as part of a broader service development initiative. Aimed at enhancing patient satisfaction, the AI callbot was designed to efficiently address queries from hospitals' primary users, especially the elderly and those using phone services. By incorporating an AI-driven callbot into the hospital's customer service center, routine tasks such as appointment modifications and cancellations were efficiently managed by the AI Callbot Agent. On the other hand, tasks requiring more detailed attention or specialization were addressed by Human Agents, ensuring a balanced and collaborative approach. The deep learning model for voice recognition for this study was based on the Transformer model and fine-tuned to fit the medical field using a pre-trained model. Existing recording files were converted into learning data to perform SSL(self-supervised learning) Model was implemented. The ANN (Artificial neural network) neural network model was used to analyze voice signals and interpret them as text, and after actual application, the intent was enriched through reinforcement learning to continuously improve accuracy. In the case of TTS(Text To Speech), the Transformer model was applied to Text Analysis, Acoustic model, and Vocoder, and Google's Natural Language API was applied to recognize intent. As the research progresses, there are challenges to solve, such as interconnection issues between various EMR providers, problems with doctor's time slots, problems with two or more hospital appointments, and problems with patient use. However, there are specialized problems that are easy to make reservations. Implementation of the callbot service in hospitals appears to be applicable immediately.