• Nutritional Sciences
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• v.8 no.4
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• pp.250-255
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• 2005

The purpose of this study was to investigate the relationship among plasma leptin, lipid profiles, insulin levels, and percentage of body fat of 72 schoolchildren from Obese Clinic Center in Seoul. The subjects divided into two groups: 39 obesity children [obesity index greater than $20\%$] who did not have a discernable medical cause of their obesity and 33 children with a obesity index less than $20\%$. The mean age, height, and obesity index of the subjects were 10.4 years, 144.0 cm, and $21.3\%$, respectively. The mean glucose and insulin levels of the obese children were 80.5 mg/dl and $13.3\;{\mu}IU/mL$ and those of the non obese children were 82.0 mg/dl and $4.2\;{\mu}IU/mL$, respectively. Obese children had significantly (p<0.05) higher level of total cholesterol, triglyceride, VLDL-cholesterol, LDL-cholesterol, and insulin concentration than non-obese children. However obese children had a lower level of HDL-cholesterol than non-obese children. Plasma leptin level were also positively correlated with BMI (p<0.000l), body fat (p<0.0001), tricep skinfold thickness (p<0.0001), mid arm circumference (p<0.0001), and waist hip ratio (p<0.0001). Plasma leptin showed a significantly positive correlation with insulin (p<0.0001), total cholesterol (p<0.0001), LDL-cholesterol (p<0.0001), and triglyceride (p<0.0001) levels, however, it was negatively correlated with HDL-cholesterol (p<0.0001) levels. In conclusion, the concentration of leptin in the blood is significantly correlated with the amount of body fat, BMI, plasma insulin, and plasma lipid profiles.

• Journal of the Korean Dietetic Association
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• v.11 no.2
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• pp.216-222
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• 2005

In Korea, there are many kinds of functional foods to manage diabetes, however, they have not been evaluated or investigated systematically. The purpose of this study was to investigate the status of recognition and intake of functional foods among diabetic patients. The study subjects were 307 patients(male 135, female 172), who diagnosed with type 2 diabetes at Seoul National University of Bundang Hospital. Questionnaire survey was done from July to October, 2004 for the characteristics of patients and factors related to the use of functional foods. The mean age of the subjects was 64$\pm$10.2 years, and the mean duration of disease was 9.5$\pm$8.90 years. Approximately 49.8% of the subjects had experience to use functional foods at least once in past. Total number of functional foods used were 56 types. Red ginseng was used most frequently(27.9%), then followed by Silkworm powder(13.6%), Vitamin supplements(10.4%), Mulberry tree(7.1%), Cordyceps sinensis(6.8%) and Ginseng(4.2%). Functional foods were introduced by their friends.relatives(38.4%), family(29.1%), internet(13.9%), and the mass media(10.6%). Among respondents, 94.7% took functional foods with conventional diet therapies(diet, exercise and medication). The purpose of functional food use was to control blood glucose level(49.0%), to relieve fatigue and improve stamina(19.9%), to treat and prevent a disease(17.2%) and to help blood circulation(7.9%). Upon the question of further recommendation of functional foods to others, 74.8% of the subjects answered negative response. However, 12.6% of the subjects showed the further intention of using new product. Therefore, to guide the appropriate use of functional foods for diabetic patients, diabetic educator should provide the knowledge of the efficacy of functional foods and the desirable guidelines.

• Korean Journal of Community Nutrition
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• v.19 no.1
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• pp.12-26
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• 2014

The purpose of this study was to investigate the relationships among serum adiponectin, leptin and vitamin D concentrations and the metabolic syndrome in Korean farmers. 105 (26 males, 79 females) farmers (39~78 years, mean age $59.4{\pm}9.6$ years) in Gangwon - area were included in this study. Anthropometric measurements and biochemical blood analysis of subjects were carried out. The prevalence of obesity, abdominal obesity, hypertension, diabetes, hypertriglyceridemia, hypercholesterolemia and hyper LDL-cholesterolemia, metabolic syndrome were 51.9%, 65.7%, 49.5%, 15.3%, 17.3%, 13.5%, 11.5% and 40.9%, respectively. Serum adiponectin and leptin levels ($8.90{\mu}g/ml$ and 12.6 ng/ml) of females were significantly higher than those ($6.49{\mu}g/ml$ and 4.88 ng/ml) of males. But there was no significant difference in 25(OH)vitamin D concentration between males (15.4 ng/ml) and females (16.9 ng/ml). In the subjects with metabolic syndrome, the adiponectin levels were significantly lower and leptin levels were significantly higher than those of the subjects without metabolic syndrome. Serum adiponectin level had positive correlations with HDL-cholesterol level (r = 0.325, p < 0.001), but showed negative correlations with triglyceride and fasting blood glucose concentrations, body weight and waist/hip circumference ratio (r = -0.202 ~ -0.317, p < 0.05). Serum leptin and 25(OH)vitamin D concentrations were positively correlated with body fat (kg, %) and BMI, waist and hip circumferences (r = 0.244 ~ 0.682, p < 0.001). The results of this study suggested that adiponectin and leptin levels could be credible indices to predict chronic diseases in farmers. However, further research on vitamin D should be carried out considering another factors.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.9
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• pp.157-166
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• 2017

This study was conducted to identify the level of diabetes self-care knowledge, confidence, behavior and quality of life in elderly people with diabetes. The participants were 205 elderly with diabetes who visited a citizen health center located in D city. Korea. The data were collected from April, 20th to August 31th, 2015, and were analyzed by the t-test and ANOVA. The results were as follows; 1) The mean scores for diabetes self-care knowledge, confidence, behavior, and quality of life were 6.99 (2.17), 71.27 (10.21), 62.78 (1.29) and 0.86, respectively. 2) There were significant differences in the self-care behavior according to the education level, duration of diabetes mellitus and subjective health, and the quality of life differeddepending on the level of subjective health(F=35.253, p=0.000). 3) Knowledge of diabetes diet was the lowest among the various aspects of diabetes self-care knowledge. Confidence for exercise was lowest, while confidence for medication and blood sugar check was highest. However, the participants exhibited good medication behavior, whereasthey did not carry out blood glucose checks in their self-care management behavior. The most uncomfortable aspect of the quality of life was found to be pain and discomfort. Based on the results of this study, it is necessary to develop guidelines and methods for dietary education reflecting the dietary habits of Koreans, and to investigatethe reasonsfor thelow performance of theblood glucose check. In addition, customized nursing interventionstaking into consideration the characteristics of elderly with diabetes need to be developed and verified.

• Clinical and Experimental Pediatrics
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• v.48 no.11
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• pp.1239-1243
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• 2005

Purpose : Iron accumulation interferes with hepatic insulin extraction and affects insulin synthesis and secretion. The purpose of this study is to investigate the correlation between serum ferritin and type 2 diabetes mellitus. Methods : We compared the serum ferritin level among 18 patients in an impaired glucose tolerance (IGT) group, 36 in a type 1 diabetes group, eight in a type 2 diabetes group and 29 in a healthy control group. The correlation between serum ferritin levels and sex, body mass indices(BMI), blood pressure(BP), serum fasting sugar level and serum fasting insulin level were also analyzed. Results : The mean log ferritin were $1.33{\pm}0.32$(healthy control group), $1.63{\pm}0.19$(IGT group) and $1.90{\pm}0.30$(type 2 diabetes group). In the IGT group, log ferritin was higher than in the healthy control group(P=0.001). The log ferritin of the type 2 diabetes group was higher than that of the healthy control group(P=0.001). Comparing log ferritin to other factors, log ferritin had a significant positive correlation with body mass indices(P<0.001), systolic blood pressure(P=0.001), and fasting glucose(P=0.001), fasting insulin(P=0.002). Conclusion : Compared to the normal healthy group, serum ferritin concentrations were significantly higher in the IGT group and the type 2 diabetes group. The elevation of serum ferritin concentration may be a risk factor of type 2 diabetes mellitus.

• Journal of Nutrition and Health
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• v.39 no.7
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• pp.641-648
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• 2006

This study was designed to evaluate the effect of the individual nutrition education for type 2 diabetes who participate the diabetes buffet. The subjects were 66 patients and divided into education (n=34) and control groups (n=32). The mean age of education and control groups were 59.8 and 56.6 years old, respectively. There were no differences in age and body mass index (BMI) between two groups. Initial glycosylated hemoglobin (HbA1c), post prandial plasma glucose (PP2), total plasma cholesterol, and blood pressure were not different between two groups. But fasting blood sugar (FBS) was higher in education group than in control group. On completion of the study, the education group showed significant decreases in body weight, BMI, FBS and PP2, however, the control group showed no changes in body weight, BMI and PP2, and showed a significant increase in FBS. Initial calorie and protein intakes of the education group did not meet the prescribed amount, however, mineral and vitamin intakes were higher than estimated average requirement (EAR). By the end of study, calorie and protein intakes were significantly increased to meet the prescription. In order to evaluate the effect of diet education, awareness of calorie requirement was used as an index of understanding diet prescription. The degree of awareness of calorie requirement was dependent on age: younger patients showed higher awareness than older subjects. The subject who showed better understanding of diet prescription showed lower levels of HbA1c, FBS, and PP2 at the end of the experiment period. The results of this study clearly show that individual diabetes diet education is effective to make the patient understand their diet prescription, and is effective to control body weight and blood sugar level. Awareness of calorie requirement could be used as an index of understanding of prescribed diet. Since age is an important variable to determine the awareness of calorie requirement, different strategies of nutrition education should be developed for different age groups, especially patients over 70 years old.

• Journal of Hospice and Palliative Care
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• v.17 no.1
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• pp.18-26
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• 2014

Purpose: Anorexia is a common symptom in terminal cancer patients. Some data have suggested a role of visfatin in regulating feeding behavior. We studied the relationship of a serum visfatin level and anorexia in cancer patients provided with hospice care. Methods: After informed consent was obtained, 69 cancer patients over 20 years old at a hospice center were enrolled in the study from July 2009 to July 2010. We characterized patients by age, sex, body mass index, primary cancer site, and Eastern Cooperative Oncology Group (ECOG) performance status, etc. Also, blood tests were performed to measure the level of hemoglobin, white blood cell (WBC), C-reactive protein (CRP), total cholesterol, albumin, lymphocyte count, glucose, blood urea nitrogen (BUN), creatinine, tumor necrosis factor-alpha (TNF-${\alpha}$), interukin-6, leptin and visfatin. Results: The mean age of subjects was 65.5 years old, According to univariate analysis, pulse, ECOG performance scale, opioid use and visfatin level were different between the anorexia and non-anorexic group (P<0.05). The median visfatin level was higher in the anorexia group than the good appetite group (P=0.0323). Serum visfatin concentrations were not related with either body mass index or serum leptin or total cholesterol levels, but it was negatively correlated with serum albumin levels (P=0.0198) and lymphocyte counts (P=0.0013). Conclusion: This study did not identify a novel link between visfatin levels and anorexia in cancer patients at a hospice.

• The Journal of Korean Academic Society of Nursing Education
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• v.4 no.1
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• pp.53-65
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• 1998

This study was designed and undertaken to analyse the factors associated with sexual satisfaction in diabetic patients. The data were collected from September to November, 1997. The subjects in this study were 77 diabetic patients who visited to check their blood glucose level to the outpatient department of internal medicine in one of hospitals located in Taejon city, The questionnaires developed by Derogatis L. R. were used. Data were analysed using percentages, means, 1-test, ANOVA and Peason-correlation coefficients, done with the SAS program. The results of this study were as follows ; 1. The mean score of sexual satisfaction in diabetic patients was higher than the mid level as 3.14 points in the 5 points scale and male patients' score was a little higher than female's. 2. The mean score of factors associated with sexual life was 3.54 points in spouses' support, 3.44 points in sexual attitude and 2.60 points in body image in the 5 points scale, and 2.76 points in the sexual act in the 6 points scale. The score of above all factors were higher in male patients than female patients. 3. The significant factors associated with sexual satisfaction were spouses' support, body image and sexual act. That is, the higher spouses' support, the more positive body image and the more frequent sexual act, the higher patients' sexual satisfaction. 4. In the relationships between the sexual satisfaction and the general characteristics of the diabetic patients, only religion and the period of disease were statistically significant differents, but the relationships between the sexual satisfaction and the period of disease showed a significant inverse correlation. This results showed that the degree of sexual satisfaction in diabetic patients was relatively high. The major factors associated with sexual satisfaction were spouses' support, body image and sexual act, religion and the period of disease. So, the above factors have to be considered during the nursing intervention on diabetic patients' sexual life.

• Journal of Preventive Medicine and Public Health
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• v.52 no.4
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• pp.242-249
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• 2019

Objectives: Elderly individuals with diabetes should maintain a normal body mass index (BMI) to help control their blood glucose levels. This study investigated barriers to physical activity (PA), self-efficacy to overcome those barriers, and PA self-efficacy among elderly individuals with diabetes in relation to BMI. Methods: This cross-sectional study included 56 participants. Data were collected by a questionnaire interview and direct measurements for anthropometric data. PA self-efficacy was measured using 8 questions describing different levels of PA, where participants rated the strength of their belief that they could engage in that activity. Self-efficacy to overcome barriers was measured using 10 questions capturing participants' confidence in their ability to engage in PA despite different possible barriers. Mean scores for these parameters were analyzed using the chi-square test and the independent t-test. Results: In total, 89.3% of participants had a low PA level and 58.9% had more than 3 hours of sedentary activity per day. Furthermore, 55.4% were obese and 14.3% were overweight. The mean scores for PA self-efficacy and self-efficacy to overcome barriers were $59.1{\pm}26.4$ and $52.5{\pm}13.8$, respectively. PA level was related to BMI (p<0.001; r=0.116) and sedentary activity (p<0.05; r=0.274). PA self-efficacy and age were not related to BMI. Barriers to PA were associated with PA levels (p<0.05). Conclusions: Physical inactivity was a major problem in elderly individuals with diabetes, and was correlated with higher BMI. Lower levels of PA might be mediated by sedentary activity.

• Asian-Australasian Journal of Animal Sciences
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• v.18 no.12
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• pp.1752-1760
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• 2005

In this experiment, the effects of cage density (CD) and probiotic supplementation (PS) on laying performance, metabolic profile, and egg quality in peak-producing hens were evaluated. After blocking according to the cage location, Lohman layers (n = 180, 46 wks of age) were allocated randomly to two levels of CD (540 vs. 360 $cm^2$/hen) and three levels of PS (0, 0.15, and 0.30%). Probiotic contained Enterococcus faecium culture (10${\times}$10$^9$ cfu/g). Egg production (EP) and feed consumption (FC) were measured daily; egg weight (EW) was measured bi-weekly; BW was measured before and after the experiment; and blood samples were obtained at the end of the experiment. The data were analyzed using two-way ANOVA. Increasing CD decreased FC (125.0 vs. 120.8 g/d, p<0.0001) and FCR (1.93 vs. 1.87, p<0.0001) and did not alter EP, EW, and BW. Increasing level of PS linearly decreased FC (p<0.02) and FCR (p<0.006). Averages were 123.9, 123.2, and 121.6 g/d for FC and 1.91, 1.92, and 1.86 for FCR in hens supplemented with 0, 0.15, and 0.30% probiotic, respectively. Hens placed in high-density cages had greater serum corticosterone concentration than hens placed in normal-density cages (12.8 vs. 11.3 $\mu$g/dL, p<0.04); CD did not affect concentrations of other metabolites. Increasing level of PS linearly increased serum glucose, albumin, and creatine concentrations and quadratically increased total protein, globulin, Ca, and P concentrations. Average concentrations (mg/dL) were 260, 297, and 305 for glucose; 6.28, 8.09, and 7.58 for total protein; 1.98, 2.48, and 2.38 for albumin; 4.30, 5.62, and 5.19 for globulin; 0.40, 0.52, and 0.54 for creatine; 16.0, 16.5, and 16.3 for Ca; and 6.27, 8.14, and 7.17 for P in hens supplemented with 0, 0.15, and 0.30% probiotic, respectively. There was no effect of CD on egg quality. Increasing level of PS linearly improved yolk color (YC) and quadratically increased albumen index (AI) and Haugh unit (HU). The mean values were 9.67, 9.75, and 10.58 for YC; 8.94, 6.93, and 8.72% for AI; and 85.6, 74.9, and 82.9 for HU for hens supplemented with 0, 0.15, and 0.30% probiotic, respectively. There was also CD by PS effect on FC, EP, and serum glucose, total protein, albumin, globulin, creatine, Ca and P concentrations. In conclusion, increased CD partially depressed laying performance and caused stress. Probiotic supplementation improved laying performance and metabolic profile. It also partially alleviated the adverse effects of stress resulting from increased caging density.