• Journal of Nutrition and Health
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• 제30권2호
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• pp.155-169
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• 1997

This study investigated the effect of weight control by using the commercial appetite suppressant ((-)-hydroxycitric acid(HCA) formula) and nutrition education on 72 obese women over a period of 8 weeks. During the study it conducted nutritional education for women to control their weight, thus analyzed their changes in anthropometric variables. All obese women were randomized in a double-blind method to consume either HCA(HCA group : experimental group) or placebo(placebo group : control group). Two groups were also divided randomly into 2 groups combined with commercial formula diet in 1 meal a day(HD group and PD group : HCA + gormula diet and placebo + formula diet) or not(HO group and conducted with 4 groups(HD, HO, PD, and PO group). All subjects were assigned to consume 800-1500kcal/d balanced diet which is 500kcal less than their usual energy requirement. To evaluate the effect of the weight control program, weight, percent of body fat, waist and hip circumferences, and 5 skinfold thickness were measured up to 5 times in all obese women. The mean weight of the subjects at the onset of the study was 76.5$\pm$10.6kg. The mean body mass index(BMI) wa 30.1$\pm$3.8 and it was in the upper 5 percentile of mean BMI of Korean women. At the end of the program, mean weight loss was 3.5kg after 2 weeks(p<0.001), and 5.8kg after 4 weeks(p<0.001). The waist, hip ratio(WHR) and skinfold thickness measurements of biceps, triceps, subscapular, suprailiac and abdominum showed significant reduction over the entire study period(p<0.05). These outcome were evaluated by effect of nutritional education and counselling. The reduction of % of body fat was significantly different among the 4 groups. Women who administrated HCA demonstrated more change in weight, BMI than the placebo group. There was also significant reduction in body composition (% of body fat, WHR, and skinfold thickness) than the other groups. The HD group which was administrated HCA combined with formula diet was more decreased than other groups. It showed that this program using commercial HCA and formula diet induced not only a change in weight but also a change in body composition. The outcome of this study suggests that HCA has a more effctive change on weight control which is carried out with nutritional education and counselling.

• 한국자동차공학회논문집
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• 제11권6호
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• pp.183-189
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• 2003

The study of the automotive noise reduction has been concentrated on the reduction of the automotive engine noise because the engine noise is the major cause of automotive noise. However, many studies of automotive engine noise led to the interest of the noise reduction of the exhaust and intake system. Recently, the active control method is used to reduce the noise of an automotive exhaust and intake system. It is mostly used the LMS(Least-Mean-Square) algorithm as an algorithm of active control because the LMS algorithm can easily obtain the complex transfer function in real-time. Especially, Filtered-X LMS (FXLMS) algorithm is applied to an Active Noise Control system. However, the convergence performance of LMS algorithm went bad when the FXLMS algorithm was applied to an active control of the induction noise under rapidly accelerated driving conditions. So, in order to solve this problem, the modified FXLMS algorithm is proposed. In this study, the improvement of the control performance using the modified FXLMS algorithm under rapidly and suddenly accelerated driving conditions was identified. Also, the performance of an active control using the LMS algorithm under rapidly accelerated driving conditions was evaluated through the theoretical derivation using a chirp signal to have similar characteristics with the induction noise signal.

• Journal of Korean Neurosurgical Society
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• 제42권4호
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• pp.305-310
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• 2007

Objective : Combined antero-posterior fixation has been a standard method for bilateral interfacetal dislocation in cervical spine. The purpose of this study is to evaluate the efficacy and complication of anterior cervical stabilization in treatment of bilateral interfacetal dislocation. Methods : A total of 65 cases of traumatic bilateral interfacetal dislocation in cervical spine who were managed in our institution, from Mar. 1997 to Feb. 2006, were included in this study. Closed reduction was tried in all cases before operation. If closed reduction was accomplished successfully, only anterior cervical fixation was performed (Group I), and attempted to place screws bicortically as possible with unicortical screws. If failed, posterior open reduction with fixation was first tried, followed by anterior cervical fixation (Group II). All patients were evaluated for neurological outcome and radiological evidence of healing. Results : The Group I included 47 patients and the Group II, 18 patients. The improvement of Frankel grade and increase of mean cervical lordosis angles were not statistically different between two groups. Screw-plate system used did not influence the outcome. On follow up, solid bone fusion was evident and there were no cases of instability in both groups. Conclusion : Our study demonstrated that anterior cervical fixation on BID is safe and effective in comparison with combined antero-posterior cervical fixation.

• Journal of the Optical Society of Korea
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• 제12권3호
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• pp.126-130
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• 2008

We propose and experimentally demonstrate an effective method to reduce near-field speckle noise at the output of a 50 ${\mu}m$ graded index multimode fiber using a short cylindrical piezoelectric transducer(PZT) vibrating in the radial direction. The fiber was coiled as tightly as possible around the mandrel of the PZT and a periodic stretching effect was caused by the radial oscillations of the actuator. The output of the optical fiber using the He-Ne laser source was intensively observed by a CCD camera. By counting all the pixels corresponding to relative intensity graded into 256 levels in the selected area and by calculating standard deviation and mean value of the intensity, we could measure the speckle contrast and vibration effect quantitatively with reduction ratio of pixels and line profile of the illuminated region. It was clearly observed that the characteristics of the speckle pattern in the vibration-on state were significantly improved over that of the vibration-off state due to time-averaged smoothing.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제43권2호
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• pp.83-87
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• 2017

Objectives: The purpose of this study is to evaluate the treatment efficacy of enucleation after decompression. Materials and Methods: A total of 17 patients with cystic lesion of the jaw were treated with decompression followed by enucleation. Pre- and post-decompression panoramic radiographs were analyzed. Results: The mean percentage of reduction after decompression was 64%. The reaction was graded as good (>80%) in five patients (29.4%), moderate (50%-80%) in nine patients (52.9%), and poor (<50%) in three patients (17.6%). The reduction rate of larger cystic lesions was faster than that of smaller lesions. However, the reduction rate was not affected by age. The duration of follow-up ranged from one to eight years. There were no complications, and one case recurred. Conclusion: Decompression is an effective method for the initial treatment of jaw cysts.

• 한국재료학회지
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• 제13권10호
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• pp.677-682
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• 2003

SiC nanowires were synthesized by carbothermal reduction using metal catalysts. Synthesized nanowires had mean diameters of 30∼50 nm and several $\mu\textrm{m}$ length. The kind of catalysts affects form of SiC nanowire because of difference of growth mechanisms. These differences were made by catalyst's physical property and relative activities to the source gas. Ni acted a conventional catalyst of VLS growth mechanism. But, Case of Fe, SiC nanowire was grown by stable VLS growth mechanism without relation of growth conditions. SiC nanowire was grown by two step growth model using Cr catalyst. Conversion ratios to the SiC nanowire were increased with growth conditions. Case of Cr, conversion ratio was about 45% that was higher than other catalyst used. This high conversion ratio was obtained by the addition VS growth to radial direction on the as-grown nanowires.

• 한국분말재료학회지
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• 제20권3호
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• pp.197-202
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• 2013

A novel route to prepare Nd-Fe-B magnetic particles by utilizing both spray drying and reduction/diffusion processes was investigated in this study. Precursors were prepared by spray drying method using the aqueous solutions containing Nd salt, Fe salt and boric acid with stoichiometric ratios. Precursor particles could be obtained with various sizes from 2 to $10{\mu}m$ by controlling concentrations of the solutions and the average size of $2{\mu}m$ of precursors were selected for further steps. After heat treatment of precursors in air, Nd and Fe oxides were formed through desalting procedure, followed by reduction processes in Hydrogen ($H_2$) atmosphere and with Calcium (Ca) granules in Argon (Ar) successively. Moreover, diffusion between Nd and Fe occurred during Ca reduction and $Nd_2Fe_{14}B$ particles were formed. With Ca amount added to particles after $H_2$ reduction, intrinsic coercivity was changed from 1 to 10 kOe. In order to remove and leach CaO and residual Ca, de-ionized water and dilute acid were used. Acidic solutions were more effective to eliminate impurities, but Fe and Nd were dissolved out from the particles. Finally, $Nd_2Fe_{14}B$ magnetic particles were synthesized after washing in de-ionized water with a mean size of $2{\mu}m$ and their maximum energy product showed 9.23 MGOe.

• 한국해안·해양공학회논문집
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• 제29권2호
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• pp.121-127
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• 2017

구조물에 작용하는 실제 파랑은 다방향 불규칙파로써 장대 구조물의 경우 파의 위상차로 인해 파력의 감소효과가 발생한다. 본 연구에서는 이러한 효과가 파괴확률에 기여하는 정도를 파악하고 기존의 모듈형 방파제에 비해 어느 정도의 안정성이 확보되는지 확인하고자 기존 방파제 및 파력감소계수를 이용한 장대케이슨 방파제의 활동 파괴모드에 대해 신뢰성해석을 수행하였다. 그 결과 기존의 모듈형 케이슨 방파제보다 장대케이슨 방파제의 신뢰도지수가 더 높게 나타났고, 설계변수 중 유의파고가 가장 높은 영향을 미치는 것으로 확인되었다. 추가로 파력감소계수의 산정에 사용되는 변수들의 평균값 변화에 따른 신뢰성해석을 수행하였으며, 해석 결과 각 변수 값과 파력감소계수의 관계에서 확인된 경향이 평균값 변화에 따른 신뢰도지수 결과의 경향에 나타나는 것을 확인할 수 있었다.

• 대한의용생체공학회:의공학회지
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• 제38권6호
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• pp.295-301
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• 2017

In this study, We subtracted the calcification blooming artifact from MDCT images of coronary atherosclerosis patients and verified their accuracy and usefulness. We performed coronary artery calcification stenosis phantom and a program to subtract calcification blooming artifact by applying 8 different image segmentation method (Otsu, Sobel, Prewitt, Canny, DoG, Region Growing, Gaussian+K-mean clustering, Otsu+DoG). As a result, In the coronary artery calcification stenosis phantom with the lumen region 5 mm the calcification blooming artifact was subtracted in the application of the mixture of Gaussian filtering and K- Clustering algorithm, and the value was close to the actual calcification region. These results may help to accurately diagnose coronary artery calcification stenosis.

• Genomics & Informatics
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• 제18권4호
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• pp.38.1-38.9
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• 2020

Chronotype is an important moderator of psychiatric illnesses, which seems to be controlled in some part by genetic factors. Clock genes are the most relevant genes for chronotype. In addition to the roles of individual genes, gene-gene interactions of clock genes substantially contribute to chronotype. We investigated genetic associations and gene-gene interactions of the clock genes BHLHB2, CLOCK, CSNK1E, NR1D1, PER1, PER2, PER3, and TIMELESS for chronotype in 1,293 healthy Korean individuals. Regression analysis was conducted to find associations between single nucleotide polymorphism (SNP) and chronotype. For gene-gene interaction analyses, the quantitative multifactor dimensionality reduction (QMDR) method, a nonparametric model-free method for quantitative phenotypes, were performed. No individual SNP or haplotype showed a significant association with chronotype by both regression analysis and single-locus model of QMDR. QMDR analysis identified NR1D1 rs2314339 and TIMELESS rs4630333 as the best SNP pairs among two-locus interaction models associated with chronotype (cross-validation consistency [CVC] = 8/10, p = 0.041). For the three-locus interaction model, the SNP combination of NR1D1 rs2314339, TIMELESS rs4630333, and PER3 rs228669 showed the best results (CVC = 4/10, p < 0.001). However, because the mean differences between genotype combinations were minor, the clinical roles of clock gene interactions are unlikely to be critical.