• Title/Summary/Keyword: Mean Curve

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Predictive value of C-reactive protein for the diagnosis of meningitis in febrile infants under 3 months of age in the emergency department

  • Lee, Tae Gyoung;Yu, Seung Taek;So, Cheol Hwan
    • Journal of Yeungnam Medical Science
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    • v.37 no.2
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    • pp.106-111
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    • 2020
  • Background: Fever is a common cause of pediatric consultation in the emergency department. However, identifying the source of infection in many febrile infants is challenging because of insufficient presentation of signs and symptoms. Meningitis is a critical cause of fever in infants, and its diagnosis is confirmed invasively by lumbar puncture. This study aimed to evaluate potential laboratory markers for meningitis in febrile infants. Methods: We retrospectively analyzed infants aged <3 months who visited the emergency department of our hospital between May 2012 and May 2017 because of fever of unknown etiology. Clinical information and laboratory data were evaluated. Receiver operating characteristic (ROC) curves were constructed. Results: In total, 145 febrile infants aged <3 months who underwent lumbar punctures were evaluated retrospectively. The mean C-reactive protein (CRP) level was significantly higher in the meningitis group than in the non-meningitis group, whereas the mean white blood cell count or absolute neutrophil count (ANC) did not significantly differ between groups. The area under the ROC curve (AUC) for CRP was 0.779 (95% confidence interval [CI], 0.701-0.858). The AUC for the leukocyte count was 0.455 (95% CI, 0.360-0.550) and that for ANC was 0.453 (95% CI, 0.359-0.547). The CRP cut-off value of 10 mg/L was optimal for identifying possible meningitis. Conclusion: CRP has an intrinsic predictive value for meningitis in febrile infants aged <3 months. Despite its invasiveness, a lumbar puncture may be recommended to diagnose meningitis in young, febrile infants with a CRP level >10 mg/L.

Analysis of Partial Least Square Regression on Textural Data from Back Extrusion Test for Commercial Instant Noodles (시중 즉석 조리 면의 Back Extrusion 텍스처 데이터에 대한 Partial Least Square Regression 분석)

  • Kim, Su kyoung;Lee, Seung Ju
    • Food Engineering Progress
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    • v.14 no.1
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    • pp.75-79
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    • 2010
  • Partial least square regression (PLSR) was executed on curve data of force-deformation from back extrusion test and sensory data for commercial instant noodles. Sensory attributes considered were hardness (A), springiness (B), roughness (C), adhesiveness to teeth (D), and thickness (E). Eight and two kinds of fried and non-fried instant noodles respectively were used in the tests. Changes in weighted regression coefficients were characterized as three stages: compaction, yielding, and extrusion. Correlation coefficients appeared in the order of E>D>A>B>C, root mean square error of prediction D>C>E>B>A, and relative ability of prediction D>C>E>B>A. Overall, 'D' was the best in the correlation and prediction. 'A' with poor prediction ability but high correlation was considered good when determining the order of magnitude.

The seismic reliability of two connected SMRF structures

  • Aval, Seyed Bahram Beheshti;Farrokhi, Amir;Fallah, Ahmad;Tsouvalas, Apostolos
    • Earthquakes and Structures
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    • v.13 no.2
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    • pp.151-164
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    • 2017
  • This article aims to investigate the possible retrofitting of a deficient building with soft story failure mode by connecting it to an adjacent building which is designed based on current code with friction dampers at all floors. Low cost and high performance reliability along with significant energy dissipation pertaining to stable hysteretic loops may be considered in order to choose the proper damper for connecting adjacent buildings. After connecting two neighbouring floors by friction dampers, the sliding forces of dampers at various stories are set in two arrangements: uniform sliding force and then variable sliding force. In order to account for the stochastic nature of the seismic events, incremental dynamic analyses are employed prior and after the installation of the friction dampers at the various floors. Based on these results, fragility curves and mean annual rate of exceedance of serviceability and ultimate limit states are obtained. The results of this study show that the collapse mode of the deficient building can affect the optimum arrangement of sliding forces of friction dampers at Collapse Prevention (CP) performance level. In particular, the Immediate Occupancy (IO) performance level is not tangible to the sliding force arrangement and it depends solely on sliding force value. Generally it can be claimed that this rehabilitation scheme can turn the challenge of pounding two adjacent buildings into the opportunity of dissipating a large amount of the seismic input energy by the friction dampers, thus improving significantly the poor seismic performance of the deficient structure.

Predicting the mortality of pneumonia patients visiting the emergency department through machine learning (기계학습모델을 통한 응급실 폐렴환자의 사망예측 모델과 기존 예측 모델의 비교)

  • Bae, Yeol;Moon, Hyung Ki;Kim, Soo Hyun
    • Journal of The Korean Society of Emergency Medicine
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    • v.29 no.5
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    • pp.455-464
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    • 2018
  • Objective: Machine learning is not yet widely used in the medical field. Therefore, this study was conducted to compare the performance of preexisting severity prediction models and machine learning based models (random forest [RF], gradient boosting [GB]) for mortality prediction in pneumonia patients. Methods: We retrospectively collected data from patients who visited the emergency department of a tertiary training hospital in Seoul, Korea from January to March of 2015. The Pneumonia Severity Index (PSI) and Sequential Organ Failure Assessment (SOFA) scores were calculated for both groups and the area under the curve (AUC) for mortality prediction was computed. For the RF and GB models, data were divided into a test set and a validation set by the random split method. The training set was learned in RF and GB models and the AUC was obtained from the validation set. The mean AUC was compared with the other two AUCs. Results: Of the 536 investigated patients, 395 were enrolled and 41 of them died. The AUC values of PSI and SOFA scores were 0.799 (0.737-0.862) and 0.865 (0.811-0.918), respectively. The mean AUC values obtained by the RF and GB models were 0.928 (0.899-0.957) and 0.919 (0.886-0.952), respectively. There were significant differences between preexisting severity prediction models and machine learning based models (P<0.001). Conclusion: Classification through machine learning may help predict the mortality of pneumonia patients visiting the emergency department.

Mid-term (2009-2019) demographic dynamics of young beech forest in Albongbunji Basin, Ulleungdo, South Korea

  • Cho, Yong-Chan;Sim, Hyung Seok;Jung, Songhie;Kim, Han-Gyeoul;Kim, Jun-Soo;Bae, Kwan-Ho
    • Journal of Ecology and Environment
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    • v.44 no.4
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    • pp.241-255
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    • 2020
  • Background: The stem exclusion stage is a stage of forest development that is important for understanding the subsequent understory reinitiation stage and maturation stage during which horizontal heterogeneity is formed. Over the past 11 years (2009-2019), we observed a deciduous broad-leaved forest in the Albongbunji Basin in Ulleungdo, South Korea in its stem exclusion stage, where Fagus engleriana (Engler's beech) is the dominant species, thereby analyzing the changes in the structure (density and size distributions), function (biomass and species richness), and demographics. Results: The mean stem density data presented a bell-shaped curve with initially increasing, peaking, and subsequently decreasing trends in stem density over time, and the mean biomass data showed a sigmoidal pattern indicating that the rate of biomass accumulation slowed over time. Changes in the density and biomass of Fagus engleriana showed a similar trend to the changes in density and biomass at the community level, which is indicative of the strong influence of this species on the changing patterns of forest structure and function. Around 2015, a shift between recruitment and mortality rates was observed. Deterministic processes were the predominant cause of tree mortality in our study; however, soil deposition that began in 2017 in some of the quadrats resulted in an increase in the contribution of stochastic processes (15% in 2019) to tree mortality. The development of horizontal heterogeneity was observed in forest gaps. Conclusions: Our observations showed a dramatic shift between the recruitment and mortality rates in the stem exclusion stage, and that disturbance increases the uncertainty in forest development increases. The minor changes in species composition are likely linked to regional species pool and the limited role of the life-history strategy of species such as shade tolerance and habitat affinity. Our midterm records of ecological succession exhibited detailed demographic dynamics and contributed to the improvement of an ecological perspective in the stem exclusion stage.

Ultrasonographic Evaluation of Diffuse Thyroid Disease: a Study Comparing Grayscale US and Texture Analysis of Real-Time Elastography (RTE) and Grayscale US

  • Yoon, Jung Hyun;Lee, Eunjung;Lee, Hye Sun;Kim, Eun-Kyung;Moon, Hee Jung;Kwak, Jin Young
    • International journal of thyroidology
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    • v.10 no.1
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    • pp.14-23
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    • 2017
  • Background and Objectives: To evaluate and compare the diagnostic performances of grayscale ultrasound (US) and quantitative parameters obtained from texture analysis of grayscale US and elastography images in evaluating patients with diffuse thyroid disease (DTD). Materials and Methods: From September to December 2012, 113 patients (mean age, $43.4{\pm}10.7years$) who had undergone preoperative staging US and elastography were included in this study. Assessment of the thyroid parenchyma for the diagnosis of DTD was made if US features suggestive of DTD were present. Nine histogram parameters were obtained from the grayscale US and elastography images, from which 'grayscale index' and 'elastography index' were calculated. Diagnostic performances of grayscale US, texture analysis using grayscale US and elastography were calculated and compared. Results: Of the 113 patients, 85 (75.2%) patients were negative for DTD and 28 (24.8%) were positive for DTD on pathology. The presence of US features suggestive of DTD showed significantly higher rates of DTD on pathology, 60.7% to 8.2% (p<0.001). Specificity, accuracy, and positive predictive value was highest in US features, 91.8%, 84.1%, and 87.6%, respectively (all ps<0.05). Grayscale index showed higher sensitivity and negative predictive value (NPV) than US features. All diagnostic performances were higher for grayscale index than the elastography index. Area under the curve of US features was the highest, 0.762, but without significant differences to grayscale index or mean of elastography (all ps>0.05). Conclusion: Diagnostic performances were the highest for grayscale US features in diagnosis of DTD. Grayscale index may be used as a complementary tool to US features for improving sensitivity and NPV.

Analysis of Composition and Diversity of Natural Regeneration of Woody Species in Jebel El Gerrie Dry Land Forest East of Blue Nile State, Sudan

  • Abuelbashar, Ahmed Ibrahim;Ahmed, Dafa-Alla Mohamed Dafa-Alla;Siddig, Ahmed Ali Hassabelkreem;Yagoub, Yousif Elnour;Gibreel, Haithum Hashim
    • Journal of Forest and Environmental Science
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    • v.38 no.2
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    • pp.90-101
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    • 2022
  • The study aims to assess composition, diversity and population indices of natural regeneration of woody species in Jebel El Gerrie forest reserve, Blue Nile State, Sudan. We conducted field work between December 2018 and January 2019. We used random sampling to collect vegetation data in the forest where we made a total of 90 circular sample plots (radius 17.84 m) and distributed them proportionally to the area of each of the four density-based vegetation classes of the forest i.e. high density (C1), medium density (C2), low density (C3) and crop land (C4). In each sample plot we identified all regenerating tree species and counted their regeneration frequencies. We calculated ecological metrics of regeneration frequency, density, abundance, richness, evenness, diversity and importance value index (IVI) and drew abundance rank curve. Results revealed that out of fifteen mature tree species present, natural regeneration of 8 species, which belong to 6 families, was observed. The relatively most frequently naturally regenerating and abundant species were Anogeissus leiocarpa and Combretum hartmannianum. Richness, evenness and diversity of regenerating species were 1.33, 0.82 and 1.7, respectively. One-way ANOVA (α=0.05) of mean regeneration densities disclosed that there were significant differences (F3,86=16.77, p=0.000) between C2 & C3 (p=0.000) and C2 & C4 (p=0.000). While regeneration of seven tree species were absent, two, two and four species were of good, poor and fair regeneration status, respectively. A comparison of mean density of natural regeneration with that of parent trees reflects a poor regeneration status of the forest. The study provides empirical results on the regeneration status of species and signifies the need for management interventions for species conservation and restoration, maintenance of biodiversity and sustainable production.

Effect of stress-strain curve changing with equal channel angular pressing on ultimate strength of ship hull stiffened panels

  • Sekban, Dursun Murat;Olmez, Hasan
    • Structural Engineering and Mechanics
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    • v.78 no.4
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    • pp.473-484
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    • 2021
  • Similar to other structures, ultimate strength values showing the maximum load that the structure can resist without damaging has great importance on ships. Therefore, increasing the ultimate strength values will be an important benefit for the structure. Low carbon steels used in ships due to their low cost and good weldability. Improving the ultimate strength values without interfering with the chemical composition to prevent of the weldability properties of these steels would be very beneficial for ships. Grain refinement via severe plastic deformation (SPD) is an essential strengthening mechanism without changing the chemical composition of metallic materials. Among SPD methods, equal channel angular pressing (ECAP) is one of the most commonly used one due to its capacity for achieving bulk ultrafine-grained (UFG) materials. When the literature is examined, it is seen that there is no study about ultimate strength calculation in ships after ECAP. Therefore, the mean purpose of this study is to apply ECAP to a shipbuilding low carbon steel to be able to achieve mechanical properties and investigate the alteration of ship hull girder grillage system's ultimate strength via finite element analysis approach. A fine-grained (FG) microstructure with a mean grain size of 6 ㎛ (initial grain size was 25 ㎛) was after ECAP. This microstructural evolution brought about a considerable increase in strength values. Both yield and tensile strength values increased from 280 MPa and 425 MPa to about 420 MPa and 785 MPa, respectively. This improvement in the strength values reflected a finite element method to determine the ultimate strength of ship hull girder grillage system. As a result of calculations, it was reached significantly higher ultimate strength values (237,876 MPa) compared the non-processed situation (192,986 MPa) on ship hull girder grillage system.

A case study of gust factor characteristics for typhoon Morakat observed by distributed sites

  • Liu, Zihang;Fang, Genshen;Zhao, Lin;Cao, Shuyang;Ge, Yaojun
    • Wind and Structures
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    • v.35 no.1
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    • pp.21-34
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    • 2022
  • Gust factor is an important parameter for the conversion between peak gust wind and mean wind speed used for the structural design and wind-related hazard mitigation. The gust factor of typhoon wind is observed to show a significant dispersion and some differences with large-scale weather systems, e.g., monsoons and extratropical cyclones. In this study, insitu measurement data captured by 13 meteorological towers during a strong typhoon Morakot are collected to investigate the statistical characteristics, height and wind speed dependency of the gust factor. Onshore off-sea and off-land winds are comparatively studied, respectively to characterize the underlying terrain effects on the gust factor. The theoretical method of peak factor based on Gaussian assumption is then introduced to compare the gust factor profiles observed in this study and given in some building codes and standards. The results show that the probability distributions of gust factor for both off-sea winds and off-land winds can be well described using the generalized extreme value (GEV) distribution model. Compared with the off-land winds, the off-sea gust factors are relatively smaller, and the probability distribution is more leptokurtic with longer tails. With the increase of height, especially for off-sea winds, the probability distributions of gust factor are more peaked and right-tailed. The scatters of gust factor decrease with the mean wind speed and height. AS/NZ's suggestions are nearly parallel with the measured gust factor profiles below 80m, while the fitting curve of off-sea data below 120m is more similar to AIJ, ASCE and EU.

Anatomic reconstruction for acromioclavicular joint injuries: a pilot study of a cost-effective new technique

  • Pattu, Radhakrishnan;Chellamuthu, Girinivasan;Sellappan, Kumar;Kamalanathan, Chendrayan
    • Clinics in Shoulder and Elbow
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    • v.24 no.4
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    • pp.209-214
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    • 2021
  • Background: The treatment for acromioclavicular joint injuries (ACJI) ranges from a conservative approach to extensive surgical reconstruction, and the decision on how to manage these injuries depends on the grade of acromioclavicular (AC) joint separation, resources, and skill availability. After a thorough review of the literature, the researchers adopted a simple cost-effective technique of AC joint reconstruction for acute ACJI requiring surgery. Methods: This was a prospective single-center study conducted between April 2017 and April 2018. For patients with acute ACJI more than Rockwood grade 3, the researchers performed open coracoclavicular ligament reconstruction using synthetic sutures along with an Endobutton and a figure of 8 button plate. This was followed by AC ligament repair augmenting it with temporary percutaneous AC K-wires. Clinical outcomes were evaluated using the Constant Murley shoulder score. Results: Seventeen patients underwent surgery. The immediate postoperative radiograph showed an anatomical reduction of the AC joint dislocation in all patients. During follow-up, one patient developed subluxation but was asymptomatic. The mean follow-up period was 30 months (range, 24-35 months). The mean Constant score at 24 months was 95. No AC joint degeneration was noted in follow-up X-rays. The follow-up X-rays showed significant infra-clavicular calcification in 11 of the 17 patients, which was an evidence of a healed coracoclavicular ligament post-surgery. Conclusions: This study presents a simple cost-effective technique with a short learning curve for anatomic reconstruction of acute ACJI. The preliminary results have been very encouraging.