• Journal of Korean Academy of Fundamentals of Nursing
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• v.9 no.1
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• pp.86-100
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• 2002

Purpose: The purpose of the study was done to identify the nursing care needs of patients in the recovery room. Method: The subjects in this study were 127 patients in a recovery room between 6/9/2001 and 24/9/2001. The instrument used for this study was the descriptive questionnaire developed by Shin Hyun-Jin (1999). The data was analysed by frequency, percentage, mean, standard deviation, t-test, ANOVA, and factor analysis using the SPSS program. Result: 1) Kaiser - Meyer -O1kin sample appropriateness was 799 and Bartlett's test of sphericity significant probability was .000. 2) The mean score for nursing care need of patients in the recovery room was $4.17{\pm}.51$ of a total possible score of 5. The score of nursing need for different parameters was as follows : Educational need ($4.31{\pm}.49$), physical need ($4.27{\pm}.47$), emotional need ($4.11{\pm}.52$), environmental need ($3.99{\pm}.56$). 3) Differences in the needs for nursing care according to the demographics were significant for gender, marital status, operation experience, and departments consulted. General characteristic variables significantly related to nursing need were as follows: Physical need significantly related to the departments consulted (F=2.23, p=.036). Educational need significantly related to the marital status (F=2.55. p=.012), departments consulted (F=2.30, p= 031). Emotional need significantly related to the marital status (F=2.22, p=.028). Environmental need significantly related to the gender (t=-2.44, p= .016), marital status (F=2.01, p= .046). operation experience (t=-1.99. p= .048). Conclusion: Nursing care needs of patients in the recovery room are significantly related to educational need, physical need, emotional need and environmental need. Intervention plans and program need to be developed to improve strategies to meet nursing needs of patients in the recovery room.

• Journal of Life Science
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• v.17 no.9 s.89
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• pp.1224-1231
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• 2007

Insulin-like growth factor-I (IGF-I) and IGF-II have structure like insulin. In contrast to insulin, however, the bioavaility of IGFs is modulated by the IGF-binding protein (IGFBPs). Each of IGFBPs was different with molecular masses, biological characteristics, and immunological properties.. Human fibroblasts secrete IGFBPs that can modify IGF-I action. In diabetes mellitus, the most study of IGF systems have been investigated in insulin-dependent diabetes mellitus, non-insulin-dependent diabetes mellitus, and streptozotocin-in-duced animals in vivo. Recently, a little research regarding the IGFs system has been proposed in por-tion of cell in vitro. In this study, effects of low or high glucose condition on IGFBP-5 in GM10 was investigated. By western blotting analysis, IGFBP-5 level decreased in cells cultured at high glucose, but IGFBP-5 level of mRNA didn't change. IGFBP-5 protease that cleaves IGFBP-5 in conditioned me-dium had was inhibited by EDTA and heparin, like serine protease and metalloprotease. Furthermore, the protease activity was increased in high glucose cultivated condition. In results of gelatin zymog-raphy, molecular weight of proteolytic metalloenzymes was indentified 69-kDa and protease activity was increased in time-dependent manner. Although the mechanism has yet to be determined, IGFBP-5 proteolysis in GM10 cells cultured with high glucose may increase effects of IGFs to decrease the glu-cose level through dissociation of IGFs from IGFBPs. Therefore, we suggest that IGF- I and IGFBPs could be potential models in study of pathophysiology such as diabetes mellitus.

• The Korean Journal of Nuclear Medicine Technology
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• v.22 no.2
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• pp.67-73
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• 2018

$[^{11}C]PIB$ synthesis has been performed by a loop-methylation and HPLC purification in our lab. However, this method is time-consuming and requires complicated systems. Thus, we developed an on-cartridge method which simplified the synthetic procedure and reduced time greatly by removing HPLC purification step. We compared 6 different cartridges and evaluated the $[^{11}C]PIB$ production yields and specific activities. $[^{11}C]MeOTf$ was synthesized by using TRACERlab FXC Pro and was transferred into the cartridge by blowing with helium gas for 3 min. To remove byproducts and impurities, cartridges were washed out by 20 mL of 30% EtOH in 0.5 M $NaH_2PO_4$ solution (pH 5.1) and 10 mL of distilled water. And then, $[^{11}C]PIB$ was eluted by 5 mL of 30% EtOH in 0.5 M $NaH_2PO_4$ into the collecting vial containing 10 mL saline. Among the 6 cartridges, only tC18 environmental cartridge could remove impurities and byproducts from $[^{11}C]PIB$ completely and showed higher specific activity than traditional HPLC purification method. This method took only 8 ~ 9 min from methylation to formulation. For the tC18 environmental cartridge and conventional HPLC loop methods, the radiochemical yields were $12.3{\pm}2.2%$ and $13.9{\pm}4.4%$, respectively, and the molar activities were $420.6{\pm}20.4GBq/{\mu}mol$ (n=3) and $78.7{\pm}39.7GBq/{\mu}mol$ (n=41), respectively. We successfully developed a facile on-cartridge methylation method for $[^{11}C]PIB$ synthesis which enabled the procedure more simple and rapid, and showed higher molar radio-activity than HPLC purification method.

• Journal of the Korean Chemical Society
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• v.60 no.1
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• pp.16-20
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• 2016

The solvolysis rate constants of biphenyl-4-carbonyl chloride (C₆H₅C₆H₅COCl, 1) in 19 different solvents are well correlated with the extended Grunwald-Winstein equation, using the N_T solvent nucleophilicity scale, Y_Cl solvent ionizing scale, and I aromatic ring parameter with sensitivity values of 0.31±0.10, 0.46±0.05, and 0.96±0.20 for l, m, and h, respectively. These l, m, and h values can be considered to support a dissciative S_N2 reaction pathway. This interpretation is further supported by the activation parameters, i.e., relatively small positive ΔH^‡ (15.3~16.1 kcal/mol) values and large negative ΔS^‡ (−17.2~−20.0 cal/mol·K) values.

• Human Ecology Research
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• v.58 no.4
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• pp.585-599
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• 2020

This study investigated children's interests in learning English, affected by educational activities in and out of institutes, and mothers' perceptions regarding early childhood English education. We recruited, 253 mothers of 3- to 5-year-old children in either general kindergartens or English immersion institutes. They answered questions on socioeconomic status, perceived interest in English by their children, their perceptions regarding early childhood English education, and English education outside institutes. In addition, 42 English teachers provided information within institutes such as class time per week, teacher-pupil rate, and language use policy during class. The collected data were analyzed through SPSS 22 for frequency analysis, descriptive statistics, independent t-test, and hierarchical multiple regression analysis. The major findings are as follows. First, the two groups were in distinct learning environment. Second, mothers' perceptions and outside-institute activities were significantly different between the two groups. Third, the English interests of children at both institutes were influenced by mothers' worries and at-home English interactions. Fourth, education within institutes did not affect both group's English interests. Fifth, private education and socioeconomic status did not affect both group's English interests. Lastly, only the children's interests in English immersion institutes were affected by gender and mother's perceived necessities. Focusing children's interests, this study helps in understanding young children's affective aspects regarding learning English. The findings are expected to be a guideline for each home and institute to increase children's interest in learning English.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.17 no.1
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• pp.13-20
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• 2007

This study was performed to investigate the concentrations of PM($PM_{10}$, $PM_{2.5}$, $PM_{1}$) and it's affecting factors in the subway from line 1 to line 8 in Seoul metropolitan area, from Sep. 1 to 30, 2005. PM concentrations were measured at the entrances and centers in subway passenger cabins by a light scattering equipment. And the affecting factors to PM were estimated based on the number of passenger, door open and close and running area etc. The geometric means of $PM_{10}$, $PM_{2.5}$ and $PM_{1}$ concentration in Seoul subway passenger cabins were $214{\mu}g/m^3$, $86.6{\mu}g/m^3$ and $27.0{\mu}g/m^3$, respectively. These mean concentrations in subway carriage were higher when it ran on an underground track than on a ground track. And running time(7AM-9AM, 11AM-13PM, 6PM-8PM) significantly influenced to the concentrations of $PM_{10}$, $PM_{2.5}$ and $PM_{1}$. Daily profile of $PM_{10}$ and $PM_{2.5}$, $PM_{1}$ expressed as an 10 minutes average, showed similar variation pattern over day period. In correlation analysis, significant relations among $PM_{10}$, $PM_{2.5}$ and $PM_{1}$ were detected(p〈0.01). In particular, correlation coefficient between $PM_{10}$and $PM_{1}$ was highly significant(r=0.94). Further study is needed to identity the sources of PM in subway cabins and to compare pollutants concentration among subway lines.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.19 no.5
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• pp.211-217
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• 2019

The three major inventions of Jeju include the field wall of Kim Koo Pan Gwan in 1234, Jeongnang in the custom of grazing the people of Jeju, and Olleh in the tomb of Munbang-gui in 1406. Field wall, Oedam from the stone and the stone of numerical play, made Koendang, a friendship society. Even with a typhoon that is more than 30m/s, the Koendang which is about 1.5m high, will not collapse. Similarly, the main family networks of Jeju society do not collapse under any difficulties situation. When building a field wall, two stones, which are under the ground, are placed side by side, and the upper left stone is placed on top and the upper right stone is attached regularly. One stone or two stone is attached from the bottom to the top, and when a stone is small or large, a flat field is formed in one space. The Family networks is close to the grandfather, grandmother, father, mother, and me, and the distant kin represents a horizontal relationship. The field wall is a vertical relationship that builds up from bottom to top of the vertical relation, while the Koendang is a horizontal relationship where blood is distributed to the grandson of his upper grandparents. This paper proves by a non-orthogonal symmetric weighted Hadamard matrix of whether the stone in the middle of a field wall has large stones (small).

• Water for future
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• v.28 no.5
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• pp.219-233
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• 1995

A non-stationary multivariate model is selected in which the mean and variance of rainfall are not temporally or spatially constant. And the rainfall prediction system is constructed which uses the recursive estimation algorithm, Kalman filter, to estimate system states and parameters of rainfall model simulataneously. The on-line, real-time, multivariate short-term, rainfall prediction for multi-stations and lead-times is carried out through the estimation of non-stationary mean and variance by the storm counter method, the normalized residual covariance and rainfall speed. The results of rainfall prediction system model agree with those generated by non-stationary multivariate model. The longer the lead time is, the larger the root mean square error becomes and the further the model efficiency decreases form 1. Thus, the accuracy of the rainfall prediction decreases as the lead time gets longer. Also it shows that the mean obtained by storm counter method constitutes the most significant part of the rainfall structure.

• Journal of Plant Biotechnology
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• v.43 no.3
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• pp.332-340
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• 2016

Seed size traits are controlled by multiple genes in crops and determine grain yield, quality and appearance. However, the molecular mechanisms controlling the size of plant seeds remain unclear. We performed functional analysis of BrPATL4 encoding Sec14-like protein to determine the genetic architecture of seed size, shape and their association analyses. We used 60 $T_3$ transgenic rice lines to evaluate seed length, seed width and seed height as seed size traits, and the ratios of these values as seed shape traits. Pleiotropic effects on general architecture included small seed size, erect panicles, decreased grain weight, reduced plant height and increased sterility, which are common to other mutants deficient in gibberellic acid (GA) biosynthesis. To test whether BrPATL4 overexpression is deleterious for GA signal transduction, we compared the relative expression of GA related gene and the growth rate of second leaf sheath supplied with exogenous $GA_3$. Overexpression of BrPATL4 did not affect GA biosynthesis or signaling pathway, with the same response shown under GA treatment compared to the wild type. However, the causal genes for the small seed phenotype (D1, SRS1, and SRS5) and the erection of panicles showed significantly decreased levels in mRNA accumulation compared to the wild type. These results suggest that the overexpression of BrPATL4 can control seed size through the suppression of those genes related to seed size regulation. Although the molecular function of BrPATL4 is not clear for small seed and erect panicles of BrPALT4 overexpression line, this study provides some clues about the genetic engineering of rice seed architecture.

• Journal of Hospice and Palliative Care
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• v.12 no.4
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• pp.199-208
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• 2009

Purpose: The purpose of this study was to analyze the effect of death preparing education on death anxiety and meaning of life for volunteers. Methods: Data collection and intervention were carried out from January 11 to 25, 2009. The subjects included 60 volunteers in Jeonju city, and they were divided into two groups; 30 each of experimental group and control group. Death preparing education program contained 5 steps. Data were analyzed with t-test, $x^2$-test, and ANCOVA test with SPSS version 12.0. Results: The death anxiety scores in the experimental group were significantly lower than in the control group (F=4.01, P=0.046). The meaning of life scores in the experimental group were significantly higher than in the control group (F=6.32, P=0.015). Conclusion: The death preparing education program for volunteers was confirmed to be an effective intervention to lessen death anxiety and to improve the meaning of life. Therefore, I strongly recommend that this program should generously be applied to volunteers.