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Development of depression diagnosis system using EEG signal (뇌파 측정 신호를 이용한 우울증 진단장치 개발)

  • Kim, Kyu-Sung;Jung, Ju-Hyeon;Lee, Woo-Cheol
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.12
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    • pp.452-458
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    • 2017
  • In this study, a device was developed for diagnosing depression using EEG signals from July 2016 to June 2017. For normal people, the left alpha rhythm is more activated than the right alpha rhythm, but for the depressed patients, the right alpha rhythm is more activated than the left one. An analog circuit and digital low pass filter were used for noise removal and amplification of EEG, and the Hamming window function was applied to eliminate the signal leakage generated by the fast Fourier transform. To verify the validity of the developed diagnosis system, the EEG of 20 university students in the 3rd and 4th grade with an average age of 24 years was measured. Calculations of the relative value of the left and right alpha rhythm for the depression diagnosis revealed a minimum, maximum, and mean value of 66.7, 113.3, and 92.2, respectively. In addition, 7 out of 20 subjects were between 90 and 95, and those with a higher mean deviation of approximately 20 tended to have mild depression. These results can provide meaningful data for the development of depression treatment equipment by solving the left and right brain asymmetry problem, and it may be applied usefully to diagnose depression after clinical trials on a large number of depressed patients.

Performance of a Hollow Fiber Membrane Bioreactor for the Treatment of Gaseous Toluene (중공사막 결합형 생물반응기를 이용한 기체상 톨루엔 제거 특성 검토)

  • Son, Young-Gyu;Kim, Yong-Sik;Khim, Jee-Hyeong;Song, Ji-Hyeon
    • Journal of Korean Society of Environmental Engineers
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    • v.27 no.8
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    • pp.886-891
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    • 2005
  • In this study, a novel bioreactor system using a submerged hollow fiber membrane module (so called hollow fiber membrane bioreactor, HFMB) was applied to investigate feasibility and biodegradation capacity of the system for the treatment of gaseous toluene. First an abiotic test was conducted to determine the mass transfer coefficient, showing the value was similar to that obtained from a diffuser system using fine bubbles. Second, in the presence of toluene-degrading microorganisms, the HFMB was operated at different inlet toluene loading rates of 50, 100, $500\;g/m^3/hr$, and overall removal efficiencies were maintained in the range of $70{\sim}80%$. In addition, elimination capacities(EC) were increased up to $800\;g/m^3/hr$, which was substantially higher than maximum ECs for toluene reported in the biofiltration literature. Consequently, the HFMB was considered as an alternative method over other conventional VOC-treating technologies.

The Methane Production from Organic Waste on Single Anaerobic Digester Equipped with MET (Microbial Electrochemical Technology) (미생물 전기화학 기술이 설치된 단일 혐기성소화조에서 유기성폐기물로부터 메탄생성)

  • Park, Jungyu;Tian, Dongjie;Lee, Beom;Jun, Hangbae
    • Journal of Korean Society of Environmental Engineers
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    • v.38 no.4
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    • pp.201-209
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    • 2016
  • Theoretical maximum methane yield of glucose at STP (1 atm, $0^{\circ}C$) is 0.35 L $CH_4/g$ COD. However, most researched actual methane yields of anaerobic digester (AD) on lab scale is lower than theoretical ones. A wide range of them have been reported according to experiments methods and types of organic matters. Recent year, a MET (Microbial electrochemical technology) is a promising technology for producing sustainable bio energies from AD via rapid degradation of high concentration organic wastes, VFAs (Volatile Fatty Acids), toxic materials and non-degradable organic matters with electrochemical reactions. In this study, methane yields of food waste leachate and sewage waste sludge were evaluated by using BMP (Biochemical Methane Potential) and continuous AD tests. As the results, methane production volume from the anaerobic digester equipped with MET (AD + MET) was higher than conventional AD in the ratio of 2 to 3 times. The actual methane yields from all experiments were lower than those of theoretical value of glucose. The methane yield, however, from the AD + MET occurred similar to the theoretical one. Moreover, biogas compositions of AD and AD + MET were similar. Consequently, methane production from anaerobic digester with MET increased from the result of higher organic removal efficiency, while, further researches should be required for investigating methane production mechanisms in the anaerobic digester with MET.

Indocyanine green excretion test and changes of plasma enzyme activites in dogs (개에서의 indocyanine green 배설시험 및 혈장효소 활성치의 변화)

  • Kim, Cheol-ho;Choi, Il-kwan;Son, Min-soo;Kim, Jin-gu;Kang, Chung-boo
    • Korean Journal of Veterinary Research
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    • v.32 no.4
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    • pp.671-675
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    • 1992
  • This experiment was carried out to establish a proper method of indocyanine green(ICG) excretion test for a applicable liver function test in dogs. The half life(T1/2), fractional clearance rate(KICG) and retention rate after injection of ICG with or without administred carbon tetrachloride($CCl_4$) were also invested. The results obtained were as follows ; 1. The maximum absorbance of ICG in plasma was at 810nm. 2. Half life and fractional clearance rate when administered 0.25 and 0.50mg of ICG per Kilogram body weight were $6.33{\pm}0.58$ minutes and $0.11{\pm}0.99$/minute in the former, $10.01{\pm}1.0$ minutes and $0.07{\pm}0.007$/minute in the latter, respectively. The ICG removal rate was exponentially linear for the first 15 minutes after injection both, of 0.25 and 0.50mg of ICG. 3. One day following the administration of $0.0042m{\ell}\;CCl_4$ kilogram body weight which injected 0.50mg of ICG, half life was more longer and fractional clearance rate was significantly reduced than that of ICG single injection. 4. Plasma retention rate when 15, 30, 45 minutes after injection dose of 0.25 and 0.50mg ICG per Kilogram body weight, $14.7{\pm}4.8$, $5.1{\pm}3.1$, $2.6{\pm}1.6%$ in the former, $26.9{\pm}1.8$, $11.1{\pm}2.4$, $4.8{\pm}1.3%$ in the latter, respectively. However, after administration of $CCl_4$, plasma retention rate of ICG at a dose of 0.50mg, it was $39.3{\pm}0.9$, $16{\pm}2.9$, $10.7{\pm}0.1%$, respectively. 5. Plasma enzyme(AST, ALT, r-GTP) activities administered with $CCl_4$ were increased, but there was no change which injected any dose of single ICG injection. From these results, ICG excretion test to dog is applicable to evaluation of liver function in both clinical and research.

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Evaluation of Chemical Pre-treatment for the Optimization of CO2 Fixatiom Using by Carbonation Reaction with Serpentine (이산화탄소 광물고정화 효율 증가를 위한 사문석의 화학적 전처리에 관한 연구)

  • Jang, Na Hyung;Shim, Hyun Min;Hua, Xu Li;Kim, Hyung Teak
    • Applied Chemistry for Engineering
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    • v.19 no.5
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    • pp.526-532
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    • 2008
  • The proposed $CO_2$ storage technology in the present study is a one-step sequestration process that stabilizes $CO_2$ in a reactor with Serpentine. The advantage of this technology is associated with its high stability of final product so that the entire system is recognized as permanent environment-friendly $CO_2$ removal method. Since the sequestration reaction mechanisms are generally understood that carbonation reaction proceeds with very slow rate, so that pretreatment method to increases reaction rate of $CO_2$ carbonation reaction should be developed. To increase the reactivity of Serpentine with $CO_2$, two different methods of pretreatment are carried out in the present investigation. One is heat-treatment, the other is chemical pretreatment. In this study, only chemical pretreatment is considered leaching method of magnesium from Serpentine using sulfuric acid at the various reaction temperatures, times, and acid concentrations. Experimental results illustrated that pretreatment by sulfuric acid increases surface area of serpentine from $11.1209m^2/g$ to $98.7903m^2/g$ and extracts magnesium compounds. Single variable experiment demonstrated the enhancements of magnesium extraction with increased reaction temperature and time. Amount of magnesium extraction is obtained by using the data of ICP-AES as maximum extraction condition of magnesium is 2 M acid solution, $75^{\circ}C$ and 1hr. After performing chemical pretreatment, carbonation yield increased from 23.24% to 46.30% of weight.

Study on the Pretreatment of Rice Hull to Enhance Enzymatic Saccharification Efficiency (효소 당화효율 증진을 위한 왕겨의 전처리 방법 연구)

  • Bark, Surn-Teh;Koo, Bon-Cheol;Moon, Youn-Ho;Cha, Young-Lok;Yoon, Young-Mi;Kim, Jung Kon;An, Gi Hong;Park, Kwang-Geun;Park, Don-Hee
    • Applied Chemistry for Engineering
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    • v.23 no.4
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    • pp.399-404
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    • 2012
  • The objective of this study was to investigate the efficient pretreatment method for bioethanol production from rice hull. Ammonia and sodium hydroxide as an alkaline solution and dilute sulfuric acid as an acidic solution were used in a batch reactor under high-temperature and high-pressure conditions. The highest enzymatic saccharification efficiency of 82.8% and ash removal rate of 94.7% were obtained in the dilute sulfuric acid treated sample after the sodium hydroxide solution treatment. The enzymatic saccharification efficiencies and ash removals of pretreated rice hull samples have very similar variation tendency. This means that the maximum obstructive factor for the enzymatic saccharification of rice hull is the ash (silicate) content in biomass. The findings suggest that the combined sodium hydroxide-dilute sulfuric acid treatment system under high-temperature and high-pressure conditions is a promising pretreatment method to enhance the enzymatic saccharification of the silica-rich biomass.

Preparation of Pelletized Porous Adsorbent with Pyrolysis Temperature and Its Toluene Gas Adsorption Characteristics (열분해 조건에 따른 펠렛형 다공성 흡착재의 제조 및 톨루엔 가스 흡착 특성)

  • Kim, Do Young;Kim, Yesol;Cho, Seho;Jung, Jin-Young;Kim, Min Il;Lee, Young-Seak
    • Applied Chemistry for Engineering
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    • v.24 no.6
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    • pp.587-592
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    • 2013
  • In this study, we prepared pelletized porous carbon adsorbent (PCA) according to the different pyrolysis temperature using activated carbon and polyvinyl alcohol (PVA) as a binder for the removal of toluene, which is one of the representative volatile organic compounds (VOCs). We investigated physical characteristics of PCA using FE-SEM, BET, TGA and evaluated their adsorption capacity for toluene using GC. It was confirmed that the formability of pellets composed of the activated carbon, PVA and solvent of mass mixing ratio was 1 : 0.2 : 0.8 was the most outstanding. Toluene adsorption capacity was evaluated by measuring the maximum time when more than 99% of toluene adsorbed on the pellet. The specific surface area of the adsorbent pyrolyzed at $300^{\circ}C$ was measured as 4.7 times in $941.9m^2/g$ compared to that of the unpyrolyzed pellet. Micropore volume and toluene adsorption capacity of PCA increased fivefold to be 0.30 cc/g and thirteenfold to be 26 hours compared to that of the unpyrolyzed pellet, respectively. These results were attributed to the change of pore size and specific surface area due to the PVA content and the different pyrolysis temperature.

Density Effect and Diversity of Fish in Water System at Both Reservoirs in the Youngsan-ri, Goseong-gun (고성군 용산리의 두 저수 수계에서 어류의 다양성과 밀도 효과)

  • Huh, Man Kyu;Choi, Byoung-Ki
    • Journal of Life Science
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    • v.25 no.5
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    • pp.533-538
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    • 2015
  • Four sites and one site were used to analyze fish diversity at the water systems of the Sineun reservoir and the Jeonchon reservoir, respectively. The field experiments were conducted to test the density dependence that could lead to population regulation by artificial inferences and environmental changes. We examined the effects of environmental factors on fish densities using SMATR freeware. It was estimated to be reduced to the density effect at four sites in 2012. Shannon-Weaver indices of the diversity (H’) of the Sineun reservoir were similar to those of the Jeonchon reservoir. Species diversity was in a range of 0.645 to 2.105. The H’ value of the upper region was higher than those of middle and low regions were, and values of richness were lower in downstream than upstream. Using the maximum likelihood solution for the removal estimators of two low regions of the river stations, the estimated migration probabilities from the resident fish to the migrated fish for five species (Cyprinus cuvieri, Carassius auratus, Pseudorasbora parva, Misgurnus mizolepis, and Oryzias latipes) had a mean of 0.623. Especially, migration probabilities from the Jeonchon reservoir to the Sineun reservoir for five species were high (a mean of 0.681). The period of migration was suggested to be about one month because of short geographical distances (50 m). We found no significant difference between the three categories in the distribution of the other four species, indicating the species probability was similar among stations.

Studies on the Removal of Phytate from Korean Perilla (Perilla ocimoides, L.) Protein (들깨종실단백질 중의 phytate 제거에 관한 연구)

  • Park, Jin-Hee;Yang, Cha-Bum
    • Korean Journal of Food Science and Technology
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    • v.22 no.3
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    • pp.343-349
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    • 1990
  • The solubility of protein and phytate was measured at various pH's in distilled water and at various concentrations of NaCl, $CaCl_2\;and\;Na_2SO_3$ solutions, and then optimum condition for producing low phytate protein isolate from perilla flour was investigated. The protein solubility in water showed minimum at pH 4.0 and increased at pH higher or lower than 4.0, while phytate solubility was highest at pH 5.0 and decreased at pH higher or lower than 5.0. In NaCl solution, protein solubility was lowest between pH 3.0-4.0, while phytate solubility was high between pH 2.0-5.0 and abruptly decreased above PH 6.0. In $Na_2SO_3$ solution, protein solubility was lowest between pH 2.0-3.0 and phytate solubility showed maximum values between pH $5.0{\sim}6.0$, and it's solubility was low in 3% salt concentration at all pH ranges. In $CaCl_2$ solution, protein solubility in 3% salt concentration was relatively low at all pH ranges, and phytate solubility showed highest values between pH $2.0{\sim}3.0$ and abruptly decreased (1.0%) above pH 4.0. In order to make low phytate protein isolate, defatted perilla flour protein was extracted at pH9.0 and precipitated at pH 4.0 in 3% NaCl solution. The yield of low phytate protein isolate was 61.4% of total protein. This protein was found to contain 0.02% phytate by weight.

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RADIOLOGICAL EVALUATION OF FRACTURE LINE STABILITY DURING FUNCTIONAL LOADING AFTER MINIPLATE FIXATION OF MANDIBULAR ANGLE FRACTURES (하악 우각부 골절의 소형금속판 내고정 후 기능시 골접합선의 안정도에 관한 방사선학적 평가)

  • Suh, Chang-Ho;Bae, Jung-Soo;Chin, Byung-Rho
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.27 no.5
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    • pp.428-434
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    • 2001
  • After miniplate fixation of mandibular angle fractures, fracture line stability during functional loading was evaluated. Using panoramic radiographs, 15 mandibular angle fracture patients who were treated by open reduction and one miniplate fixation along the external oblique ridge, were evaluated at postoperative 1, 4 and 8 weeks. At each time, 2 radiographs were taken: one taken during maximum biting of hardened silicone sheet on the affected side molar area and the other on the non-affected side. The distraction gap of inferior border of mandible at each time and each side was measured and these data were analysed statistically with clinical findings. The differences of inferior border distraction gap during hardened silicone sheet biting on the affected side molar area and on the non-affected side molar area at 4 week radiographs were smaller than those of 1 week's except one case. At 8 week's radiographs, the fracture lines were so stabilized that it was almost impossible to find the gap differences except one case and there were increased radiopacity along the entire fracture lines. Clinically, bony union was confirmed in all cases during plate removal performed at postoperative 6 month. By statistical analysis(paired t-test), the inferior border distraction gap during biting of hardened silicone sheet on the affected side was significantly reduced during 1 and 4 week interval(p<0.01). The differences of inferior border distraction gap during biting on the affected side molar area and on the non-affected side molar area were also significantly reduced at 1 and 4 week interval(p<0.01). But the inferior border distraction(compression) gap during non-affected side biting was not significantly changed. From these findings, it could be concluded that fracture line stability during functional loading after one miniplate fixation of mandibular angle fractures stems mainly from reduction of inferior border distraction gap during affected side biting on time interval. According to these radiographic and clinical findings, the clinical superiority of one miniplate fixation technique in mandibular angle fracture treatment could be confirmed.

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