• 제목/요약/키워드: Matrix of knowledge

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Enamel matrix derivative for replanted teeth in animal models: a systematic review and meta-analysis

  • Kim, Sahng G.;Ryu, Steven I.
    • Restorative Dentistry and Endodontics
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    • 제38권4호
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    • pp.194-203
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    • 2013
  • Objectives: To investigate the effect of enamel matrix derivative (EMD) on periodontal healing of replanted teeth in animal models. Materials and Methods: The authors searched MEDLINE, PubMed, EMBASE, Cochrane Library, Web of Knowledge and Scopus for articles published up to Oct 2012. Animal studies in which EMD was applied in transplanted or replanted teeth with adequate controls and histological data were considered. Normal periodontal healing or root resorption determined by histology after EMD was applied in replanted teeth with adequate controls was used as outcome measures. The following search strategy was used: ('Emdogain' OR 'enamel matrix proteins' OR 'enamel matrix derivative') AND ('avulsion' OR 'transplantion' OR 'autotransplantation' OR 'replantation'). Results: Six animal studies were included in the final review. There was great heterogeneity in study design among included studies. Two studies with similar study designs were identified and analyzed by a meta-analysis. The pooled estimates showed a significantly higher normal healing and surface resorption and significantly less inflammatory and replacement resorption in EMD-treated groups compared with non-EMD-treated groups. Conclusions: With the limitations of this systematic review, the use of EMD led to greater normal periodontal healing and surface root resorption and less inflammatory and replacement root resorption in the presence of periodontal ligaments. However, no definite conclusion could be drawn with regard to the effect of EMD on periodontal healing and root resorption when no periodontal ligaments exist.

Leveraging and Fostering Diversity in the IS Discipline: Intradisciplinary Knowledge Building via the IT View-IS Phenomenon (VP) Matrix

  • Inchan Kim;Jama Summers
    • Asia pacific journal of information systems
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    • 제34권1호
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    • pp.49-90
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    • 2024
  • Intradisciplinary research refers to research that integrates ideas often associated with different research domains in a discipline. Such cross-fertilization leverages abundant diversity present in the IS discipline to tackle increasingly complex IS problems and grand challenges. Despite its importance and recent attention, a concerted, sustained effort toward intradisciplinary research is lagging. A fundamental issue we see is a lack of an elaborate IS research map that effectively shows similarities and differences among research domains and demonstrates types of ideas that may travel and integrate into different domains. We thus aim to propose an elaborate IS research map and compile research elements that can be tried and combined across research domains. To do so, we utilize two IS classics (i.e., IT views and IS phenomena), identify their complementarity, and interweave the two disparate ways of portraying the IS research field. The resultant view-phenomenon (VP) matrix specifies research domains based on two consistent, comprehensive criteria and helps researchers discern similarities and differences among research domains more effectively. The VP matrix also sheds light on a variety of research elements that can flow across research domains. The VP matrix along with the research elements together facilitate intradisciplinary efforts and, more broadly, help the IS discipline to prosper. The VP matrix is particularly helpful for doctoral students and young scholars.

인적 자원 소속성 분석을 위한 역할-수행자 이분 행렬 생성 알고리즘 (A Role-Performer Bipartite Matrix Generation Algorithm for Human Resource Affiliations)

  • 김학성
    • 디지털콘텐츠학회 논문지
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    • 제19권1호
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    • pp.149-155
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    • 2018
  • 본 논문에서는 BPM기반 인적 자원 소속성 분석을 위한 역할-수행자 이분 행렬 생성 알고리즘을 제안한다. 제안된 알고리즘은 정보제어넷 기반의 비즈니스 프로세스 모델로부터 역할-수행자 소속 관계를 추출하는 단계와 이로부터 역할-수행자 이분 행렬을 생성하는 단계로 구성된다. 결론적으로 생성된 행렬은 역할-수행자 소속성 네트워킹 지식을 발견하기 위한 데이터 구조로서 활용될 뿐 아니라 소셜 네트워크 분석 기법을 적용하여 BPM 기반 인적 자원 소속성 분석 결과를 도출할 수 있다.

네트워크분석을 통한 직업건강간호학회지 논문의 지식구조 분석 (Knowledge Structure of the Korean Journal of Occupational Health Nursing through Network Analysis)

  • 권선영;박은정
    • 한국직업건강간호학회지
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    • 제24권2호
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    • pp.76-85
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    • 2015
  • Purpose: The purpose of this study was to identify knowledge structure of the Korean Journal of Occupational Health Nursing from 1991 to 2014. Methods: 400 articles between 1991 and 2014 were collected. 1,369 keywords as noun phrases were extracted from articles and standardized for analysis. Co-occurrence matrix was generated via a cosine similarity measure, then the network was analyzed and visualized using PFNet. Also NodeXL was applied to visualize intellectual interchanges among keywords. Results: According to the results of the content analysis and the cluster analysis of author keywords from the Korean Journal of Occupational Health Nursing articles, 7 most important research topics of the journal were 'Workers & Work-related Health Problem', 'Recognition & Preventive Health Behaviors', 'Health Promotion & Quality of Life', 'Occupational Health Nursing & Management', 'Clinical Nursing Environment', 'Caregivers and Social Support', and 'Job Satisfaction, Stress & Performance'. Newly emerging topics for 4-year period units were observed as research trends. Conclusion: Through this study, the knowledge structure of the Korean Journal of Occupational Health Nursing was identified. The network analysis of this study will be useful for identifying the knowledge structure as well as finding general view and current research trends. Furthermore, The results of this study could be utilized to seek the research direction in the Korean Journal of Occupational Health Nursing.

정보통신 기술지식의 파급효과에 대한 실증분석 (An Empirical Analysis on the Diffusion Impact of IT Technological Knowledge)

  • 조형곤;박광만;이영용;박용태;김문수
    • 기술혁신연구
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    • 제8권1호
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    • pp.73-94
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    • 2000
  • The main objective of this research is to examine the spillover effects of technological knowledge from IT industry to other industrial sectors and, based on empirical findings, to draw policy implications and suggest policy directions. To this end, we divide IT industry into IT equipment and IT service, assuming that these two sub-sectors are considerably different each other in terms of technology knowledge flow. Other industries are classified into 17 different sectors based on the KSIC of 1990. As the proxy measure of technological knowledge, the notion of R&D stock is employed. The Input/output(I/O) Table is used to define the inter-industrial flow pattern and to draw the knowledge flow matrix. As the research methodology, cost function model is employed to gauge the spillover effects of technological knowledge of IT industry. Based on the results of analysis, it is found that the economic impact of technology diffusion also exhibits a different pattern between IT equipment and IT service. The diffusion of IT equipment tends to show labor-substitution effect whereas IT service displays labor-creation effect. This fact should be considered in devising industry, education, and labor policy. The expectations from this research are as follows. First, the sectoral pattern, difference between IT equipment and service in particular, identified from this research may shed light on the sector-specific policy direction. It is emphasized that a sector-specific approach, rather than an aggregate approach, is relevant for formulating IT policy. Second, it is expected that the importance of technology diffusion programs and policy measures are recognized among policy makers in IT industry.

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네트워크 분석을 통한 암 생존자 지식구조 연구 (A Study on the Knowledge Structure of Cancer Survivors based on Social Network Analysis)

  • 권선영;배가령
    • 대한간호학회지
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    • 제46권1호
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    • pp.50-58
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    • 2016
  • Purpose: The purpose of this study was to identify the knowledge structure of cancer survivors. Methods: For data, 1099 articles were collected, with 365 keywords as a Noun phrase extracted from the articles and standardized for analyzing. Co-occurrence matrix were generated via a cosine similarity measure, and then the network analysis and visualization using PFNet and NodeXL were applied to visualize intellectual interchanges among keywords. Results: According to the result of the content analysis and the cluster analysis of author keywords from cancer survivors articles, keywords such as 'quality of life', 'breast neoplasms', 'cancer survivors', 'neoplasms', 'exercise' had a high degree centrality. The 9 most important research topics concerning cancer survivors were 'cancer-related symptoms and nursing', 'cancer treatment-related issues', 'late effects', 'psychosocial issues', 'healthy living managements', 'social supports', 'palliative cares', 'research methodology', and 'research participants'. Conclusion: Through this study, the knowledge structure of cancer survivors was identified. The 9 topics identified in this study can provide useful research direction for the development of nursing in cancer survivor research areas. The Network analysis used in this study will be useful for identifying the knowledge structure and identifying general views and current cancer survivor research trends.

Identification of matrix metalloproteinases secreted by human hepatocarcinoma HepG2 cells

  • Lee, Young Jae;Kim, Keun Cheon;Lim, Jeong Mook;Lee, Seung Tae
    • 한국동물생명공학회지
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    • 제37권1호
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    • pp.62-66
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    • 2022
  • To date, the development of anticancer drugs has been conducted using two-dimensional (2D) cell culture systems. However, since cancer cells in the body are generated and developed in three-dimensional (3D) microenvironments, the use of 2D anticancer drug screening can make it difficult to accurately evaluate the anticancer effects of drug candidates. Therefore, as a step towards developing a cancer cell-friendly 3D microenvironment based on a combination of vinylsulfone-functionalized polyethylene glycol (PEG-VS) with dicysteine-containing crosslinker peptides with an intervening matrix metalloproteinase (MMP)-specific cleavage site, the types of MMPs secreted from human hepatocarcinoma HepG2 cells, a representative cancer cell, were analyzed transcriptionally and translationally. MMP3 was confirmed to be the most highly expressed protease secreted by HepG2 cells. This knowledge will be important in the design of a crosslinker necessary for the construction of PEG-based hydrogels customized for the 3D culture of HepG2 cells.

Use of Acellular Biologic Matrix Envelope for Cardiac Implantable Electronic Device Placement to Correct Migration into Submuscular Breast Implant Pocket

  • Peyton Terry;Kenneth Bilchick;Chris A. Campbell
    • Archives of Plastic Surgery
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    • 제50권2호
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    • pp.156-159
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    • 2023
  • Breast implants whether used for cosmetic or reconstructive purposes can be placed in pockets either above or below the pectoralis major muscle, depending on clinical circumstances such as subcutaneous tissue volume, history of radiation, and patient preference. Likewise, cardiac implantable electronic devices (CIEDs) can be placed above or below the pectoralis major muscle. When a patient has both devices, knowledge of the pocket location is important for procedural planning and for durability of device placement and performance. Here, we report a patient who previously failed subcutaneous CIED placement due to incision manipulation with prior threatened device exposure requiring plane change to subpectoral pocket. Her course was complicated by submuscular migration of the CIED into her breast implant periprosthetic pocket. With subcutaneous plane change being inadvisable due to patient noncompliance, soft tissue support of subpectoral CIED placement with an acellular biologic matrix (ABM) was performed. Similar to soft tissue support used for breast implants, submuscular CIED neo-pocket creation with ABM was performed with durable CIED device positioning confirmed at 9 months postprocedure.

XCM Biologic Tissue Matrix xenograft and autologous micromucosa graft for vaginal reconstruction in Mayer-Rokitansky-Küster-Hauser syndrome

  • Gomes, Tatiana Gigante;Agostinho, Mariana;Cardoso, Mariana Conceicao;da Costa, Joao Nunes;Matias, Julio
    • Archives of Plastic Surgery
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    • 제48권2호
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    • pp.185-188
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    • 2021
  • Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome can be treated through numerous surgical and nonsurgical methods. We present a surgical technique in which a neovagina was reconstructed and shaped by a vaginal expander with acellular porcine dermal matrix (XCM Biologic Tissue Matrix) and mucosal interposition using microfragments harvested from the hymen. In our case, we found this procedure to be safe and effective, resulting in satisfactory sexual function and good cosmetic results, without donor site morbidity. To our best knowledge, this tissue-engineered biomaterial has never been used for vaginal reconstruction before.

MIMO Channel Capacity and Configuration Selection for Switched Parasitic Antennas

  • Pal, Paramvir Kaur;Sherratt, Robert Simon
    • ETRI Journal
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    • 제40권2호
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    • pp.197-206
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    • 2018
  • Multiple-input multiple-output (MIMO) systems offer significant enhancements in terms of their data rate and channel capacity compared to traditional systems. However, correlation degrades the system performance and imposes practical limits on the number of antennas that can be incorporated into portable wireless devices. The use of switched parasitic antennas (SPAs) is a possible solution, especially where it is difficult to obtain sufficient signal decorrelation by conventional means. The covariance matrix represents the correlation present in the propagation channel, and has significant impact on the MIMO channel capacity. The results of this work demonstrate a significant improvement in the MIMO channel capacity by using SPA with the knowledge of the covariance matrix for all pattern configurations. By employing the "water-pouring algorithm" to modify the covariance matrix, the channel capacity is significantly improved compared to traditional systems, which spread transmit power uniformly across all the antennas. A condition number is also proposed as a selection metric to select the optimal pattern configuration for MIMO-SPAs.