• Perspectives in Nursing Science
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• 제11권1호
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• pp.1-9
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• 2014

Purpose: The purpose of this study was to demonstrate a two-year global health project to improve maternal and child health (MCH) in Ethiopia. Methods: This is a descriptive case study. The target area is Kilte Awlaelo Woreda in Tigray Regional State, Ethiopia. A baseline survey was conducted to identify the needs of community residents and health care professionals. A MCH program was developed according to a project design matrix that included: infrastructure renovation of health centers; continuing education for midwives, nurses, and health extension workers (HEWs); and improvement of residents' MCH awareness. Project evaluation will examine the structure, process, and outcomes of the program. Results: The baseline survey showed low rates of family planning (31%) and antenatal and postnatal care use (36.1% and 69%, respectively). The institutional birth rate was 13.5%. Midwives and nurses received 2~4 educational programs about family planning and perinatal care. HEWs were also given practical education. Water and electrical infrastructure of all five health centers in the Kilte Awlaelo Woreda were renovated. Additionally, medical supplies and equipment were provided. Community health education on perinatal care, family planning, and personal hygiene was presented. Conclusion: This study highlights the role of nursing in global health and provides basic information on the development and outcomes of the global health project.

• 아동학회지
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• 제38권3호
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• pp.33-48
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• 2017

Objective: This study examined the relationships among sleep problems, executive function and social behavior during the preschool period. In addition, the mediating role of executive function between sleep problems and social behavior was investigated. Methods: A total of 304 preschool children participated in this study. The data were collected through maternal reports. Results: First, preschoolers' sleep problems were found to be significantly related to overt aggression and prosocial behavior. Second, preschoolers with sleep problems displayed lower levels of executive function. Third, preschoolers' executive function was significantly associated with social behavior. Lastly, preschoolers' executive function fully mediated the relationship between sleep problems and overt aggression, and between sleep problems and prosocial behavior. That is, preschoolers' sleep problems had effects on overt aggression and prosocial behavior, only through the effects on executive function. Conclusion: This study contributes to the sleep literature by examining the role of executive function and emphasizes the importance of forming a healthy sleep habit during the preschool period.

• 운동영양학회지
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• 제13권1호
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• pp.23-28
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• 2009

The expression of c-Fos and c-Jun represents neuronal activity and plays a crucial role in the shaping of the development of brain. During the late pregnancy, exercise is known to influence neuronal activity of offspring. In the present study, the effect of swimming during pregnancy on the expression of c-Fos and c-Jun in the CA1, CA2, CA3 regions, and the dentate gyrus of the hippocampus of rat offspring was investigated using immunohistochemistry. Pregnant rats in the swimming group were forced to swim for 10 min once a day from 15 days after pregnancy until delivery. The expression of c-Fos and c-Jun in the CA1, CA2, CA3 regions, and the dentate gyrus of the hippocampus of pups was significantly increased by maternal swimming during late pregnant period. The present results show that prenatal swimming may enhance the neuronal activity of pups and affect the neonatal brain development.

• 한국발생생물학회지:발생과생식
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• 제3권1호
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• pp.69-74
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• 1999

인슐린 유사 성장 호르몬 1과 2 (IGF-1 & IGF-2)는 착상 전 초기배아 발생을 조절하는 중요한 요소이다. 생쥐 착상 전 초기배아에서 IGF-1의 역할에 관한 연구를 위해, IGF-1과 IGF-1 수용체의 전사물의 존재 여부를 난자와 착상 전 초기배아에서 조사하였다. 새로이 고안된 IGF-1 primer를 이용하여 난자에서 전사물을 검출하였다. 그리고, PCR 산물을 제한효소인 Msp I으로 절단하여 확인하였다. 이 실험에서 IGF-1과 IGF-1 수용체의 전사물이 난자와 착상 전 초기배아에서 모두 검출됨을 보였다. GV-난자에 다량 존재하는 mRNA는 4- 혹은 8-세포기까지 지속적으로 감소하다가 이후에 다시 증가하는 양상을 보였다. GV-난자에서 IGF-1과 IGF-lR 전사물이 존재한다는 것은 초기배아에 존재하는 전사물이 모계유래 산물임을 암시한다. 또한, 난자와 착상 전 초기배아에 IGF-1과 IGF-1 수용체 전사물이 존재하는 것으로 보아 착상 전 초기배아에서 IGF-1은 자가 분비되어 IGF-1 수용체의 신호전달 경로를 통하여 배아발생에 작용하는 것으로 사료된다.

• 한국발생생물학회지:발생과생식
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• 제2권2호
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• pp.197-203
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• 1998

포유류 배아발생 중 DNA 메틸화는 세포분화와 유전자발현에서 중요한 역할을 하는 것으로 알려져 있다. 그러나, 생쥐 착상전 초기배아 발생 중 메틸화효소에 의해 유지되는 DNA 메틸화의 중요성과 자세한 기작은 잘 이해되고 있지 않다. 이 연구에서 DNA 메틸화의 역할에 관하여 알아보기 위하여, 성숙난자와 착상전 초기배아에서 DNA 메틸전이효소의 발현양상을 조사하였다. 이를 위해, DNA 메틸전이효소를 암호화하고 있는 cDNA에서 primer를 고안하였다. Primer의 정확도와 PCR조건의 적합화를 통하여, DNA MTase 전사물이 성숙난자와 착상전 초기배아에서 검출되었다. DNA MTase의 mRNA량은 성숙난자에서 가장 높으며, 전핵시기까지 비슷한 정도로 유지되었다. 이후 8-세포기까지 지속적으로 감소하다 상실기 배아에서 다시 검출되어 포배기까지 증가하는 양상을 보였다. 그리고, RNA polymerase II 억제제를 전핵시기 배아에 처리하여, 난자와 전핵시기 배아에 다량 존재하는 전사물이 모계유래인 것을 확인하였다. 결국, 난자와 전핵시기 배아에 상대적으로 다량 존재하는 DNA 메틸전이효소의 전사물은 아마도 착상전 초기배아에서 DHA 메틸화의 유지에 필요하며, 착상전 초기배아 발생에 있어서 유전자발현과 세포분화에 영향을 줄 것임을 시사하고 있다.

• 한국보육지원학회지
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• 제10권2호
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• pp.133-151
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• 2014

본 연구는 어머니가 만 2세 자녀와 함께 가상/역할 놀이와 책 읽기의 두 맥락에서 상호작용하는 동안 어머니가 사용하는 정신 상태 용어의 특성을 살펴보고 비교하는 데 그 목적이 있다. 연구대상은 서울시에 거주하는 36쌍의 어머니-만 2세 자녀 쌍이었다. 연구결과 어머니들은 책 읽기 맥락보다 가장/역할 놀이 맥락에서 정신 상태 용어를 더 많이 사용하였으나 세 가지 유형의 정신 상태용어를 사용하는 비율은 맥락에 따라 다르지 않았다. 두 맥락 모두에서 욕구 상태 언어를 정서 상태나 인지 상태 용어보다 자주 사용하였으나 어머니들이 사용하는 욕구 상태, 정서 상태, 인지 상태 용어는 개인 별로 편차가 매우 심했고, 하나의 맥락에서 정신 상태 용어를 많이 사용하는 어머니들은 다른 맥락에서도 정신 상태 용어를 많이 사용하였다. 본 연구의 결과는 자녀의 마음이론 발달에 기여하는 어머니 역할에 대한 실천적 시사점을 갖는다.

• Journal of Nutrition and Health
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• 제26권6호
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• pp.661-671
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• 1993

The change in fatty acid composition in brain tissue of the second generation rats(Sprague-Dawley strain) was studied using four different fat diets(Corn oil=CO, Soybean oil=SO, Perilla oil=PO, Fish oil=FO, 10% by Wt). The experimental diets were started from pregnancy in four different groups, each consisting of 9 rats. The seound generation rats were fed the same diet as their mothers. Animals were anesthetized with ether at 0, 3, 9 & 16 weeks of age. Whole brains were dissected out, brain tissues were, then, homogenized and lipids were extracted from brain tissues. The fatty acid compositions were measured after methylation by gas-liquid chromatography at 0, 3, 9 and 16 weeks of age of offspring. The changes in the relative concentrations of polyunsaturated fatty acids(PUFA) or more specifically docosahexaenoic acid(22 : 6, $\omega$3, DHA), the major $\omega$3 fatty acid component in rat brain at different age were similar to changes in the amount of DNA in brain tissue showing the maximum value during the lactation. The changes in saturated fatty acid(SFA) content showed a contrasting patten to those of PUFA, while monounsaturated fatty acid(MUFA) increased steadily throughout the experimental period. At birth, the relative concentrations of $\omega$3 series fatty acids the relative concentrations of PUFA, MUFA and SFA converged to very similar values respectively regardless of the dietary fatty acid compositions. In brain tissue, it is of value to note that while changes in relative concentrations of linoleic acid (18 : 2, $\omega$6, LA) and arachidonic acid(20 : 4, $\omega$6, AA) showed a precursor-product-like relationship, $\alpha$-linolenic acid(18 : 3, $\omega$3, $\alpha$-LnA) and DHA showed a different pattern. Even when the $\omega$3 fatty acid content in very low in maternal diet(CO), the second generation rat brain tissues appeared to secure DHA content, suggesting an essential role of this fatty acid in the brain. The fact that a large amount of $\alpha$-LnA in the maternal diet did not have a significant effect on the second generation rat brain $\alpha$-LnA content, indicated that DHA seemed essential component for the brain development in our experimental condition. In all groups, the relative content of $\alpha$-LnA in the brain tissues remained relatively constant throughout the experimental period at the very low level. The study of the specific concentrations and essential role(s) of DHA in each parts of brain tissue is needed in more details.

• Perspectives in Nursing Science
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• 제11권2호
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• pp.101-108
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• 2014

Purpose: The purpose of this study was to compare parenting stress between married migrant women and Korean women. Methods: Subjects were 68 married migrant women and 70 Korean women raising children aged seven years or younger, living in three different cities in Gangwon Do. To measure parenting stress, we used Kim's (1997) questionnaire that had been modified from Richard & Abidin's (1990) Parenting Stress Index (PSI). Results: There were significant differences between the two groups in age, academic credentials, job, monthly income, and achievement of maternal role. No statistically significant differences were found for parenting stress scores (p<.355), but there was a significant difference in the child characteristics of parenting stress (p<.007) between the two groups. There were no differences in the demographic variables influencing parenting stress between the two groups. Conclusion: The development of multi-cultural parenting and family support programs should consider the nationality and marital satisfaction of the family.

• 가정과삶의질연구
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• 제19권3호
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• pp.41-51
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• 2001

The purpose of this study was to investigate the relationships between mothers involvement of their childrens peer interaction, their memory of childhood peer relations, and their perception of childrens social competence. Subject consisted of 302 mothers of 4- to 6-year-old children. A sample of mothers completed a series of questionnaires assessing their peer experiences, perceptions about their childrens sociability, and a behavioral checklist of their involvement activities. The results indicated that mothers own sociability and their perceptions of their childrens sociability influenced their involvement. More intense maternal involvement occurred when mothers perceived their children to be sociable. Mothers with sociable peer recollections appeared to take more active role in their childrens social development.

• 아동학회지
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• 제30권3호
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• pp.85-98
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• 2009

The purpose of this study was to examine the path model of child's sex, temperament, maternal parenting behavior, and child's emotion regulation on child social behaviors. The subjects were 286 elementary school children. Data were gathered through questionnaires reported by mothers and teachers. Path analysis revealed that (1) mother's overprotective or coercive parenting behaviors effected neither child's emotion regulation nor social behaviors (2) child's sex and activity level effected child's aggression both directly and indirectly through child's emotion regulation (3) child's 'activity level' and 'avoidance' temperament effected child's social withdrawal both directly and indirectly through child' emotion regulation. Findings underscore the role of emotion regulation as a mediator in predicting child aggression and social withdrawal.