Journal of Nutrition and Health
- Volume 26 Issue 6
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- Pages.661-671
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- 1993
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- 2288-3886(pISSN)
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- 2288-3959(eISSN)
Effect of Maternal Dietary $\omega$ 3 and $\omega$ 6 Polyunsaturated Fatty Acids on the Fatty Acid Composition of the Second Generation Rat Brain
어미 쥐의 $\omega$ 3계 및 $\omega$ 6계 지방산 식이가 제2세대 쥐의 뇌조직 지방산 성분에 미치는 영향
Abstract
The change in fatty acid composition in brain tissue of the second generation rats(Sprague-Dawley strain) was studied using four different fat diets(Corn oil=CO, Soybean oil=SO, Perilla oil=PO, Fish oil=FO, 10% by Wt). The experimental diets were started from pregnancy in four different groups, each consisting of 9 rats. The seound generation rats were fed the same diet as their mothers. Animals were anesthetized with ether at 0, 3, 9 & 16 weeks of age. Whole brains were dissected out, brain tissues were, then, homogenized and lipids were extracted from brain tissues. The fatty acid compositions were measured after methylation by gas-liquid chromatography at 0, 3, 9 and 16 weeks of age of offspring. The changes in the relative concentrations of polyunsaturated fatty acids(PUFA) or more specifically docosahexaenoic acid(22 : 6,
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