• Neonatal Medicine
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• 제18권2호
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• pp.391-394
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• 2011

저자들은 다형 홍반과 구강 궤양으로 발현하였고 빈혈, 혈소판 감소증, 간기능 이상 등을 동반한 신생아 루푸스 환아의 확진과 신생아 진단을 통하여 무증상 산모 루푸스를 역으로 진단한 1례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

• Clinical and Experimental Pediatrics
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• 제48권1호
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• pp.85-87
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• 2005

저자들은 피부 병변과 간기능 이상이 동반된 신생아 루푸스 1례를 경험하여 보고하는 바이다.

• Neonatal Medicine
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• 제28권3호
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• pp.139-142
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• 2021

Macrophage activation syndrome (MAS) is a potentially life-threatening complication in many autoimmune diseases. Early recognition and intervention are essential for a favorable outcome. Neonatal lupus, an acquired autoimmune disease in neonates caused by the transplacental passage of maternal autoantibodies, is rare and usually self-limited. Herein, we report a case of MAS in a patient with neonatal lupus, which improved with intravenous immunoglobulin.

• Clinical and Experimental Pediatrics
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• 제48권3호
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• pp.342-345
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• 2005

저자들은 전신성 홍반성 루푸스 산모에서 출생한 생후 1개월된 신생아에서 매우 드물게 나타나는 항-$U_1RNP$ 항체 양성으로 인한 신생아 홍반성 루푸스 1례를 경험하였기에 그 임상적 특징을 문헌고찰과 함께 보고하는 바이다.

• Clinical and Experimental Reproductive Medicine
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• 제26권2호
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• pp.265-269
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• 1999

Thrombocytopenic patients without detectable bound antiplatelet antibody should be diagnosed with idiopathic thrombocytopenic purpura (ITP) if no other cause of their decreased platelet count could be found. More recently the term "autoimmune thrombocytopenic purpura (ATP) has supplanted ITP since the disease is related to the production of autoantibodies against one's own platelets. This entity should not be confused with isoimmune thrombocytopenic purpura (also called alloimmune thrombocytopenic purpura). In this cases maternal antiplatelet antibodies directed against the PLA 1 antigen on the fetal platelets causes severe fetal and neonatal thrombocytopenia in a situation analogous to Rheusus disease. Antibodies to the negatively charged phospholipids, lupus anticoagulant, and anticardiolipin have been linked to adverse pregnancy events. Pregnant women possessing these antibodies have an increased risk of spontaneous abortion, stillbirths, intrauterine fetal growth retardation, preterm birth, and arterial and venous thrombosis. Antiphospholipid antibodies decrease or may even disappear between pregnancies only to recur with increased activity in a subsequent pregnancy and lead to loss. We have experienced a case of antiphospholipid syndrome associated with autoimmune thrombocytopenic purpura in patient with recurrent spontaneous abortion. So we report this case with a brief review of literatures.