Neonatal Medicine

The Korean Society of Neonatology (대한신생아학회)
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A Case of Neonatal Lupus Erythematosus and Retrospectively Diagnosed with Asymtomatic Maternal Lupus Erythematosus

다형 홍반으로 발현한 신생아 루푸스와 역진단된 산모 루푸스 1례

  • Han, Ji-Yeon (Department of Pediatrics, College of Medicine, Konyang University) ;
  • Yoon, Jung-Min (Department of Pediatrics, College of Medicine, Konyang University) ;
  • Kim, June-Bum (Department of Pediatrics, College of Medicine, Konyang University) ;
  • Lim, Jae-Woo (Department of Pediatrics, College of Medicine, Konyang University) ;
  • Lee, Young-Hyuk (Department of Pediatrics, College of Medicine, Konyang University) ;
  • Ko, Kyong-Og (Department of Pediatrics, College of Medicine, Konyang University)
  • 한지연 (건양대학교 의과대학 소아청소년과학교실) ;
  • 윤정민 (건양대학교 의과대학 소아청소년과학교실) ;
  • 김준범 (건양대학교 의과대학 소아청소년과학교실) ;
  • 임재우 (건양대학교 의과대학 소아청소년과학교실) ;
  • 이영혁 (건양대학교 의과대학 소아청소년과학교실) ;
  • 고경옥 (건양대학교 의과대학 소아청소년과학교실)
  • Published : 2011.11.30
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Abstract

Neonatal lupus erythematosus (NLE) is a rare disease characterized by typical clinical features and the transplacental passage of maternal autoantibodies, particularly anti-SSA/Ro. The major clinical manifestations are cutaneous lupus lesions, congenital heart block, hematological disorders, and hepatobiliary diseases. We report a case of NLE presenting with multiple round and oval target-like erythematous skin lesions and abnormal liver function, born to a clinically asymptomatic mother whose diagnosis was made retrospectively only after her newborn's diagnosis. Both the infant and the mother were positive for the anti-SSA/Ro and anti-SSB/La antibodies.

저자들은 다형 홍반과 구강 궤양으로 발현하였고 빈혈, 혈소판 감소증, 간기능 이상 등을 동반한 신생아 루푸스 환아의 확진과 신생아 진단을 통하여 무증상 산모 루푸스를 역으로 진단한 1례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

Keywords

References

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