• Journal of Menopausal Medicine
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• 제24권3호
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• pp.183-187
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• 2018

Objectives: The present mini review aimed to summarize the existing knowledge regarding the beneficial and adverse effects of raloxifene in menopausal women. Methods: This study is a review of relevant publications about the effects of raloxifene on sleep disorder, depression, venous thromboembolism, the plasma concentration of lipoprotein, breast cancer, and cognitive function among menopausal women. Results: Raloxifene showed no significant effect on depression and sleep disorder. Verbal memory improved with administration of 60 mg/day of raloxifene while a mild cognitive impairment risk reduction by 33% was observed with administration of 120 mg/day of raloxifene. Raloxifene was associated with a 50% decrease in the need for prolapse surgery. The result of a meta-analysis showed a significant decline in the plasma concentration of lipoprotein in the raloxifene group compared to placebo (standardized mean difference, -0.43; 10 trials). A network meta-analysis showed that raloxifene significantly decreased the risk of breast cancer (relative risk, 0.572; 95% confidence interval, 0.327-0.881; P = 0.01). In terms of adverse effects of raloxifene, the odds ratio (OR) was observed to be 1.54 (P = 0.006), indicating 54% increase in the risk of deep vein thrombosis (DVT) while the OR for pulmonary embolism (PE) was 1.05, suggesting a 91% increase in the risk of PE alone (P = 0.03). Conclusions: Raloxifene had no significant effect on depression and sleep disorder but decreased the concentration of lipoprotein. Raloxifene administration was associated with an increased risk of DVT and PE and a decreased risk of breast cancer and pelvic organ prolapse in postmenopausal women.

• 한국보육지원학회지
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• 제6권1호
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• pp.23-45
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• 2010

본 연구는 우리나라 취업모와 보육시설에 다니는 24-48개월 자녀 67쌍을 대상으로 이들의 정서적 가용성 경향을 알아보고 어머니와 아동의 정서적 가용성을 설명하는 취업모와 아동 관련 변인은 무엇인지 조사하였다. 어머니-아동의 정서적 가용성은 Biringen, Robinson과 Emde(1998)가 개발한 정서적 가용성 척도(Emotional Availability Scales: EA, 3rd)를 사용하였고, 어머니의 일/가족 갈등, 어머니의 양육 스트레스, 어머니의 우울수준, 아동기질, 개인적 배경을 측정하였다. 본 연구 결과는 다음과 같다. 취업모와 보육시설에 다니는 24-48개윌 된 자녀의 정서적 가용성은 전체적으로 중간점수 보다 약간 높은 수준으로 나타났다. 취업모 관련변인에 따른 어머니-아동 정서적 가용성의 차이에서는 취업모의 교육 수준, 가정의 경제적 수준이 유의하였으며, 어머니-아동 정서적 가용성과 자녀와의 관계로 인한 양육스트레스 간에는 유의한 부적 상관관계가 나타났다. 아동 관련변인에 따른 어머니-아동 정서적 가용성의 차이에서는 아동이 보육시설에 처음 등원한 시기 변인만 유의한 경향이 나타났다. 취업모와 아동 관련변인 중 가정의 경제적 수준, 자녀관계 양육스트레스, 아동의 보육시설 첫 등원 시기가 어머니의 민감성과 아동의 반응성차원을 20%정도 유의하게 설명하였다.

• Asian Pacific Journal of Cancer Prevention
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• 제17권2호
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• pp.545-552
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• 2016

Background: The purpose of this study was to explore the effectiveness of a spiritual care training package in maternal caregivers of children with cancer. Materials and Methods: This study was a quasi-experimental study with pretest and posttest design consisting of a sample of 42 mothers of children diagnosed as having cancer. Participants were randomly assigned to either an experimental or a control group. The training package consisted of seven group training sessions offered in a children's hospital in Tehran. All mothers completed the Spirituality & Spiritual Care Rating Scale (SSCRS) and the Depression, Anxiety and Stress Scale (DASS-21) at pre and post test and after a three month follow up. Results: There was significant difference between anxiety and spiritual, religious, Personalized care and total scores spiritual care between the intervention and control groups at follow-up (P<0.001).There was no statistically significant difference in stress and depression scores between the intervention and the control groups at follow-up. Conclusions: Findings show that spiritual care training program promotes spirituality, personalized care, religiosity and spiritual care as well as decreasing anxiety in mothers of children with cancer and decreases anxiety. It may be concluded that spiritual care training could be used effectively in reducing distressful spiritual challenges in mothers of children with cancer.

• Asian-Australasian Journal of Animal Sciences
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• 제15권6호
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• pp.767-771
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• 2002

Breeding efficiencies were compared among three population schemes: a single population, a population with two subpopulations and a population with three sub-populations. A simulation experiment of selection was carried out for 10 generations with 20 replications each by comparing average breeding values and inbreeding coefficients among the three population schemes. Phenotypes of three traits were generated with a model comprising 36 loci, each with additive genetic effects and residuals distributed normally. Among the three population schemes, the single population scheme was definitely superior to the other two with regards to selection response and inbreeding. The multiple sub-population scheme was, however, considered to be an alternative population scheme when the difference in economic weights of the traits was small among the sub-populations, assuming moderate inbreeding depression for traits and crossbreeding. The scheme with two sub-populations had a higher genetic value than that with three subpopulations; however, the genetic values of the schemes were comparable when maternal heterosis was taken into account. The choice of population schemes may depend on the cost-sharing policy between the breeding population and the commercial population rather than just the breeding efficiency.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제13권1호
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• pp.177-188
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• 2002

연구 목적：정신과 치료를 받고 있는 청소년 중 외톨이 혹은 왕따인 청소년과 비외톨이인 청소년의 문제 행동 및 이들의 어머니의 양육 태도를 비교 분석한다. 연구 방법：청소년 정신과 환자 25명에게 외톨이 설문지, 왕따 설문지를 작성하도록 하였고, 이들의 어머니에게 아동청소년 행동평가척도(Child Behavior Checklist, CBCL)중 8개 하위 요인, 자녀양육태도 척도(Maternal Behavior Research Instrument, MBRI)의 일부, 자녀에 대한 관심 척도 등을 작성하도록 하였다. 외톨이 설문지 및 왕따 설문지 점수를 근거로 15명의 외톨이-왕따 집단과 10명의 비외톨이 집단으로 나눈 뒤, 두 집단 간의 나머지 설문지 점수를 비교하였고, 또한 외톨이 설문지와 왕따 설문지의 점수와 나머지 설문지 점수의 상관관계를 알아보았다. 결 과：1) CBCL의 8개 하위 요인(p<.05), 우울/불안 하위 요인(p<.05) 및 사고 문제 하위 요인(p<.01)에서 외톨이-왕따 집단의 점수가 비외톨이 집단의 점수보다 유의하게 높았다. 또한, 외톨이 설문지 점수는 CBCL의 8개 하위 요인(r=.516), 우울/불안 하위 요인(r=.483), 사고 문제 하위 요인(r=.651), 사회적 미성숙 하위요인(r=.517)과 유의한 상관관계를 보였으며, 왕따 설문지 점수는 CBCL의 주의력 문제 하위 요인(r=.414), 사고 문제 하위 요인(r=.446), 사회적 미성숙 하위 요인(r=.531)과 유의한 상관관계를 보였다. 2) 그러나, MBRI 점수 및 자녀에 대한 관심 척도 점수에서는 두 집단간에 유의한 차이를 보이지 않았으며, 외톨이 설문지 혹은 왕따 설문지 점수와 MBRI 점수 혹은 자녀에 대한 관심 척도 점수 사이의 상관관계에서도 통계적으로 유의한 결과를 보이지 않았다. 결 론：정신과 치료를 받고 있는 청소년 중 외톨이-왕따에 해당되는 청소년의 어머니는 비외톨이 청소년의 어머니보다 자녀들의 사고 문제 및 우울/불안 등의 정서적 문제를 더 높게 평가하였다. 그러나, 자녀들에 대한 양육 태도에 대해서는 차이를 두지 않는 것으로 보인다. 향후 보다 많은 환자들을 대상으로 한 추가 연구가 필요할 것이다.

• 가정간호학회지
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• 제8권1호
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• pp.5-24
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• 2001

The purpose of this study was to develop a parenting intervention program and determine the efficacy of the program with low-birth weight infants and their mothers. Nine dyads for the experimental group and twelve dyads for the control group discharged from the Neonatal Intensive Care Unit of a University Hospital in Seoul were recruited for the study. For the intervention group, programmed education and support which focused on the maternal sensitivity of the infant's behavior. rearing environment. motherinfant interaction and infant care were given to each subject. Individual counseling and home visits were provided at discharge, one week after discharge. and one and three months of corrected age in every infant. Structured questionaires were administered and feeding interactions were videotaped and coded by a blinded certified observer. A Quasi-experimental design was conducted for this study. Postpartum depression, maternal self esteem. infant care burden, HOME. mother-infant interaction, and infant development were measured. Results were in favor of the intervention versus the control group. On the Beck depression inventory, intervention mothers showed decreasing trends in depressive symptom vs control mothers although, there were statistically no significant differences between the two groups at each time. The mean score of experimental group was 11.55(mild depression state) at discharge and became 8,6(normal state) at 1 month of corrected age. On the other hand, the mean score of the control group was 13.92(mild depression state) at discharge and became 14.0. Maternal self esteem in both groups improved over time. Infant care burden in both groups was also shown to increase over time. There was a significant difference between the two groups in HOME(p=.0340) at 3 months of corrected age. HOME scores of the experimental group and the control's were 31.10 and 25.58, respectively. Mothers' emotional and language responses were significantly high in the intervention group compared with the control group(p=.0155). Intervention group (53.33) showed a significantly high quality of motherinfant interaction compared with the in control group (42.80)(p =.0340). Intervention group mothers appeared have a better quality of mother-infant interaction behaviors. On the other hand, there was no statistical difference in the infant part between groups. Intervention group infants had higher trends in a general developmental quotient: although, there was no statistical difference between groups. The general developmental quotient of intervention infants was 102.56 and control's was 91.28. However, the developmental quotient of the domain of 'individuality-sociality' was higher in the intervention group infants compared with the control's(p=.0155). The concerns identified by parents revealed two domains of an infants' health management -knowledge and skills in caregiving of lowbirthweight-infants, characteristics of lowbirthweight infants, identifying a developmental milestone, coping with emergency situations and relaxation strategies of mothers from the infant care burden. Interview data with the mothers of low-birth weight infants can be used to develop intervention program contents. Limited intervention time and frequency due to time and cost limitations of this study should be modified. The intervention should be continuously implemented when low-birth weight infants become three years old. An NNNS demonstration appeared to be a very effective intervention for the mothers to improve the quality of mother-infant interactions. Therefore intervening in the mothers of low-birth weight infants as early after delivery as possible is desirable. This study has shown that home visit interventions are worthwhile for mothers only beyond the approach as an essential factor in ability of facilitating a growth fostering environment. In conclusion. the intervention program of this study was very effective in enhancing the parenting for the mothers of low-birth weight infants, resulting in health promotion of low-birth weight infants. The home-visit outreach intervention program of this study will contribute to the health delivery system in this country where there is a lack of continuous follow-up programs for low-birth weight infants after discharge from NICU, if it is activated as part of the home visit programs in community health systems.

• Safety and Health at Work
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• 제11권1호
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• pp.19-25
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• 2020

Background: Childbirth represents a significant transition for women, with physical and psychological sequelae. Reentry to the workplace during the postpartum period is understudied, with implications for maternal well-being and job-related outcomes. This study's aim was to examine selected pregnancy, childbirth, and return-to-work correlates of overall self-rated health within the first month of work reentry after maternity leave. Methods: Between December 2016 and January 2017, we surveyed women employed at a large, public Midwestern university who had given birth in the past five years (N = 249) to examine self-rated overall health in the first month of work reentry. Using ordinal logistic regression, we examined whether physical or psychological health problems during pregnancy, childbirth complications, length of maternity leave, and depression and anxiety at work reentry were related to overall health. Results: Women who experienced depression (odds ratio [OR] = 0.096 [95% confidence interval {CI} = 0.019 to 0.483, p = 0.004]) and anxiety (OR = 0.164, [95% CI = 0.042 to 0.635, p = 0.009]) nearly every day reported worse health at work reentry than those with no symptoms. Controlling for demographics and mental health, women who experienced medical problems during pregnancy (OR = 0.540 [95% CI = 0.311 to .935, p = 0.028]) were more likely to report poor health, while taking a longer maternity leave (OR = 14.552 [95% CI = 4.934 to 42.918, p < 0.001]) was associated with reporting better health at work reentry. Conclusion: Women who experience medical complications during pregnancy, return to the workplace too soon after birth, and experience mental health symptoms are vulnerable physically as they return to work.

• 여성건강간호학회지
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• 제24권1호
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• pp.49-57
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• 2018

Purpose: Postpartum fatigue can impact maternal well-being and has been associated with levels of perceived self-care. This study aimed to examine the relationship among fatigue, depressive mood, self-care agency, and self-care action among postpartum women in Bangladesh. Methods: A descriptive cross sectional survey was done with 124 first-time mothers from two tertiary hospitals in Dhaka, Bangladesh. The Modified Fatigue Symptoms checklist, Denyes' Self Care Instrument, the Edinburgh Postnatal Depression Scale, and items on sociodemographic and delivery-related characteristics, were used in Bengali via translation and back-translation process. Results: High fatigue levels were found in 18.5% (n=23) and 73.4% had possible depression (n=91). There was a significant negative relationship between fatigue and self-care agency (r=-.31, p<.001), and self-care action (r=-.21, p<.05). Fatigue differed by level of self-care agency (t=4.06, p<.001), self-care action (t=2.36, p=.023), newborn's APGAR score (t=-2.93, p=.004), parental preparation class participation (F=15.53, p<.001), and postpartum depressive mood (t=-4.64, p<.001). Conclusion: Findings suggest that high level of self-care efficacy and behaviors can contribute to fatigue management, and highlight the need for practical interventions to better prepare mothers for postpartum self-care, which may, in turn, alleviate postpartum fatigue.

• 융합정보논문지
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• 제8권6호
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• pp.1-7
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• 2018

본 연구는 산욕기 산모의 삶의 질 에 영향을 미치는 요인을 파악하기 위해 시도 되었다. 본 연구는 D광역시 지역에 거주하는 출산 후 6-8주 이내의 여성 113명을 대상으로 한 서술적 조사연구이며 자료는 SPSS 21.0 프로그램을 이용하여, 기술통계, ANOVA, t-test, Pearson's correlation coefficient 및 Multiple regression analysis를 실시하였다. 자료수집은 2018년 8월부터 2018년 9월까지 하였다. 본 연구결과는 다음과 같다. 삶의 질에 가장 큰 영향요인은 양육스트레스(${\beta}=-.646$, p<.001), 피로(${\beta}=-.329$, p=.009)순으로 확인되었다. 양육스트레스(r=-.647, p<.01), 산후우울(r=-.826, p<.01), 피로(r=-.760, p<.01)는 삶의 질과 유의미한 상관관계를 보였다. 출산 후 산모는 공허감, 산후우울감 등 정서적 기분변화를 느끼는 경우 삶의 질 저하로 이어지기 때문에 산욕 기간 동안 신체적, 정신적 건강관련 간호중재 프로그램을 개발하는 것이 필요할 것이다.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제34권1호
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• pp.30-36
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• 2023

Objectives: This study examined the changes in anxiety and depressive symptoms in the parents of Korean adults with autism spectrum disorder (ASD) after participating in the Korean version of the Program for the Education and Enrichment of Relational Skills for Young Adults (PEERS^® -YA-K). Methods: Forty-six parents were enrolled (mean age 54.7 years; 22 fathers and 24 mothers), of whom 27 participated in the PEERS^® - YA-K as social coaches. Participants completed self-report scales, including the Test of Young Adult Social Skills Knowledge (TYASSK), Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), and Symptom Check-List-90-R (SCL-90-R). The scales were administered three times: before and after the 16-week program and 4 months after the program ended. Differences between participant variables at pretreatment, post-treatment, and follow-up were analyzed using paired-sample t-tests. Results: Participants showed a significant improvement in their social skills knowledge (TYASSK) (p<0.01). There was a significant improvement in the BAI and BDI scores of parents with severe depressive and anxiety symptoms at the baseline (p<0.05). Paternal paranoia and maternal hostility results also significantly improved on the SCL-90-R. Conclusion: This study suggests that PEERS^® -YA-K can reduce parental anxiety and depressive symptoms. To the best of our knowledge, this is the first to compare the degree of depression and anxiety after PEERS^® -YA-K in parents of adults with ASD.