• YAKHAK HOEJI
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• v.44 no.5
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• pp.379-383
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• 2000

Stanozolol (STZ, 17$\alpha$-methyl-17$\beta$-hydroxy-5$\alpha$-androstano-(3,2-c) pyrazole), an anabolic steroid, is an abused drug by body-builders or atheletes, as well as medicine for treatment of aplastic anemia and vascular thrombosis. In human volunteers, the major urinary metabolite of STZ was reported to be 3'-hydroxystanozolol that was identified by gas chromatography-mass selective detector (GC/MSD). The objective of this experiment is to investigate the in vitro metabolism of STZ in liver S-9 faction of polychlorinated biphenyl-induced rats. Reaction mixture including STZ as substrate and the S-9 faction was extracted with diethyl ether and quantified by the selected ion monitoring mode of GC/MSD. The selected concentration of substrate STZ is 100 nmole and the selected time for incubation in the reaction mixture was determined to 60 min. The amount of 3'-hydroxystanozolol produced was increased by about 6-fold in the reaction medium including the liver S-9 fraction of polychlorinated biphenyl-induced rats, compared to that of untreated rats. Inhibitors of cytochrome P450, SKF-525A and 7,8-benzoflavone, decreased the production of 3'-hydroxystanozolol by about 89~100% and 65~75%, respectively; In conclusion, hydroxylation of STZ into 3'-hydroxystanozolol is confirmed by GC/MSD and is catalyzed by cytochrome P450.

• Journal of Environmental Health Sciences
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• v.26 no.2
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• pp.108-115
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• 2000

The mass fraction of PM10 had a bimodal distribution in the middle of between 2.1 ${\mu}{\textrm}{m}$, and the average mass fraction of particles less than 2.1~3.1 ${\mu}{\textrm}{m}$ was 54.1% for Pb and 890.8 ng/㎥ for Fe, respectively. For the concentration of PM10 and metallic elements by seasonal variation, PM10 showed bimodal distribution, while metallic elements showed different distributions by their sources. The ratios of fine particles to total mass were 0.45 for PM10, 0.41 for Cr, and 0.20 for Fe, 0.57 for Zn, 0.68 for Cd and 0.63 for Pb, respectively. That facts indicated that PM10, Zn, Cd, Cr and Pb were from anthropogenic sources, and Fe was from natural source. The geometric means and geometric standard deviations by seasonal variations were 3.6 ${\mu}{\textrm}{m}$ , 2.31 ${\mu}{\textrm}{m}$ in winter, 3.0 ${\mu}{\textrm}{m}$ , 2.49 ${\mu}{\textrm}{m}$ in spring, 2.7 ${\mu}{\textrm}{m}$ , 2.03 ${\mu}{\textrm}{m}$ in summer respectively. And, total efficiency of cascade impactor by seasonal variations were 49.6% in winter, 45.9% in spring and 44.5% in summer.

• Transactions of the Korean Society of Machine Tool Engineers
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• v.14 no.2
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• pp.55-61
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• 2005

The machining Parts must be Produced within the specification of drawing and those will be able to meet faction and efficiency. At that time, it is very important not only precision machine and machining technique but also the measurement technique. So, the improvement of measurement technique is to be joined together at once with improvement of machining technique. Finally, the quality and value of the parts are decided by precision measurement. This paper aims to study on the measurement uncertainty when the machined parts are inspected with 3-dimensional coordinate measuring machine. The objectives remove an error of measurement and remove a quality of mass products.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.24 no.3
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• pp.402-410
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• 2000

As the combustion process of CWM consists of the water evaporation, the release and combustion of volatile matter, and the combustion of char for every particle, it is more complex than that of existent liquid fuel. Though the many studies on CWM combustion have been carried out by the single droplet using hanging methods or the multiple droplet using atomization methods, any report don't presents definite solution about the effects by the initial water evaporation and combustion of volatile. When CWM is suddenly exposed in the high temperature surroundings, the internal water evaporates and then each droplet builds up pores. Besides, porosity rate changes along the temperature of surroundings, the composition ratio of CWM, and the initial diameter of droplet. In result, because it affects the whole combustion rate, the combustion of CWM has complex mechanism as compared with the combustion of liquid or gas fuel. Therefore, concentrating on porous structure of CWM, this study has proceeded to acquire the basic data on the CWM injection combustion and closely examines the effects of the first stage combustion on the whole combustion by measuring the diameter variations, pore rate, mass fraction burned, and the internal temperature changes of CWM droplet. The results demonstrate that $60{\sim}70%$ of initial mass is reduced during water evaporation and volatile combustion period, and swelling rate, mass faction burned, and density variation are greatly concerned with atomization of CWM etc.

• Transactions of the Korean Society of Automotive Engineers
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• v.5 no.4
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• pp.70-83
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• 1997

We made a selection of engine operating conditions in the natural aspiration type diesel engine as load and speed. The effects on the power, smoke emission and cylinder pressure characteristics of these variations in operating conditions were observed experimentally. Also, the smoke emission was predicted by using the Arrhenius equation and empirical equation of the smoke emission was made. At the same time, the correlations, between the combustion and smoke emission characteristic were examined. From the above results, it is clear that to prevent power dropping and to decrease exhaust fume whin the conditions are changed, one should improve the intake system. To do this, the best way is to lower the air-fuel mixing ratio. We found that the parameters of the indicated mean effective pressure, maximum pressure and its location and combustion duration, etc. change the motion in accordance with the conditions described above. Also, we found that the variation of the pressure cycle comes from an amplified variation of the early part of process. From the analysis of comparing combustion and exhaust fume, the exhaust fume is produced at the latter time of combustion and decreased when the combustion ratio is higher. Also, we developed a special formula which can predict the exhaust fume value according to the engine load and speed.

• Journal of Korean Academy of Nursing
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• v.26 no.4
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• pp.833-852
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• 1996

Regular long term dance movement could be one of ways to induce improvement of psychophysiological variables, resulting in improvement of quality of life. However, there have been few studies to evaluate the effect of dance movement training on both physiological and psychological variables in the elderly. This study was focused to determine the effect of Korean traditional dance movement training on psychophysiological variables-body weight, body fat, lean body mass, muscle strength, muscle endurance, flexibility, agility, resting heart rate and blood pressure, depression and life satisfaction-in Korean elderly women. Thirty four subjects, aged between 65 and 75years who have normal cognition, sensory function, cerebellum function, cardiovascular function, participated in this study. Seventeen experimental group subjects were selected from E-elderly university in Kyung Gi province, and Seventeen control group subjects were selected from N-welfare facility in Seoul City. Seventeen experimental group subjects participated for 12weeks dance movement program. Korean traditional dance movement program was developed on the basis of Korean traditional dance and music by the author. The program consisted of approximately 50minutes of dance, 3times a week for 12weeks. During 50minutes workout, there were 15minutes of warm-up dancing, 25minutes of conditioning dance and 10minutes of cool-down dancing. The intensity for the conditioning phase was at between 60% and 65% of age-adjusted maximum heart rates. The body weight, body fat, lean body mass, muscle strength(grip strength, leg strength), muscle endurance, flexibility, agility, resting heart rate and blood pressure, depression and life satis-faction were measured prior to and following the experimental treatment. The participants in dance movement were interviewed focusing on subjective feeling following 12 week's regular dance movement. Data were analyzed with mean, standard deviation, percentage of change, X²-test, t-test, and ANCOVA test using SPSS PC/sup +/ program. Subjective feeling was categorized into cognitopsy-chological and physiological responses. Results were obtained as follows : 1) The body weight (F=15.52, p=.000), body fat (F=18.33, p=.000) and lean body mass (F=7.28, p=.011) of the experimental group were significantly lower than those of the control group following the dance movement training. 2) The leg strength (F=30.96, p=.000), muscle endurance (F=9.06, p=.005), agility(F=44.92, 000), flexibility(F=6.84, p=.014) of the experimental group were significantly higher than those of the control group following the dance movement training. There was no significant difference of grip strength(F=.43, p=.515) between experimental and control groups. 3) The heart rate(F=26.96, p=.000), systolic (F=10.40, p=.000) and diastolic(F=3.99, p=.005) blood pressure at rest of the experimental group were significantly lower than those of the control group following the dance movement training. 4) No significant difference of score of depression (F=3.49, p=.071) was observed between experimental and control groups. 5) Score of life satisfaction of experimental group was remarkably higher than that of control group following 12weeks of dance movement training (p<0.05). 6) Thematic responses about the dance movement following the training were positive. "I feel good" was the most frequent among cognitopsychological responses and "I feel lightness of body" was the most frequent among physiological responses. The results suggest that Korean traditional dance movement training can improve psychophysiological variables of Korean elderly.

• Journal of Applied Tourism Food and Beverage Management and Research
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• v.8
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• pp.123-144
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• 1997

This study, by setting the systems of room sale promotion, analyzing the actual status and the present working state with its center on the 'RHotel' that is a special grade-two hotel and the sales promotion activities of each type, intends to understand the presentstatus of the hotel and present its problems and the method for improvement. The strategy of salespromotion and the ineffectivenessof the system organization were found to be imminent in the sales promotion activities as its problems, and the importanceis being not attached to the actual substance rather than to the actualresults, such as the advertisement and publicity strategies, the irrationality of sales personnel controland its evaluation method, and therefore, the goal-oriented control is not being takenad its problems are emerging. Therefore, as an improvement plan, we ought to put the plan of the hotel merchandising into action for customers to buy what they want, the establishment of the customer-oriented sales promotionservice and the communication channel using the brand-new managerial skills, systemaizesales promotion method sand strategies, develop the organizational and systematic strategies develop the organizatinal and systemactic strategies and goods for the sake of the image-making and room sales promotion of hotels, develop the activation ways of flexible operation, and also need to develop the skills of sales promotion. Accordingly, by doing irrationalsales activities in the system and the promotion with its center on the sales promotion department, and it sis urgently required that we streng then the comodity developments fitting the hotel's traits, such as uniformpolicy of cost, mass-communicationactivities for sales promotion, the improvement of non-effectiveness, and advertisement of hotel items, and the publishing of public relation books. Therefore, the best weapon for hotels before other purchaseis to be discriminatized from other competitive hotel with theunderstanding of the psychology and activities of customers, and the communicatin with customers, and to set up organicprograms of sales promotionstrategies. Also we must promote our sales in accordance with the desire of new customers, gater the market information of customers, all the time, and systematize the facility improvement, managerial policy, business strategiescorresponding with the desire of customers. By doing so, we are able to seek, at the same time, both the satis faction of customers and the sales maximization of the hotels that will perfrom the activities of sales promotion and management.

• Korean Journal of Food Science and Technology
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• v.34 no.2
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• pp.311-318
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• 2002

A new bacteriocin producing lactic acid bacteria having antagonistic activity against Lactobacillus plantarum, was isolated from Kimchi. It was identified as Leuconostoc mesenteroides, and designated as Leuconostoc mesenteroides B7. The bacteriocin from Leuconostoc mesenteroides B7 named as bacteriocin B7 was stable in the pH range $2.5{\sim}9.5$. Bacteriocin B7 was active over a wide temperature range from $4^{\circ}C$ to $120^{\circ}C$. It was inactivated by proteinase K, trypsin, ${\alpha}-chymotrypsin$, and protease treatments indicating its proteinous nature. Tricine-SDS-PAGE of the purified bacteriocin B7 showed the presence of a single band, having a molecular mass of about 3,500 dalton. Mixed culture of the producer and the indicator, Lb. plantarum KFRI 464 or Lb. delbruekii KFRI 347, increased production of bacteriocin B7. This result suggested the presence of bacteriocin inducing factor in the indicator strain. The inducing factor was localized in cell debris and intracellular faction of the indicator cell, Lb. plantarum KFRI 464. Treatment of the inducing factor with proteinase K destroyed inducing activity. This result strongly suggested that the inducing factor is a protein.