• Journal of The Geomorphological Association of Korea
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• v.18 no.1
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• pp.101-112
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• 2011

Coastal terrace was developed at 7.2m height near Shinchon village in Geoje Island. It is located on the east side of southern coast in Korean Peninsula, where sea-level changes caused by ebb and flow of the tide, embayment are relatively low. Due to the breccia layer by mass-movement, dark grayish clayey formation, marine origin's rounded gravel are deposited sequentially in a cross-section of coastal terrace, so it provides a good example which understand Holocene sea level changes to determine the effect on the various sedimentary environments. For the purpose of identifying the morphogenetic process, Grain size, Roundness, XRD, AMS dating analysis was attempted. As a result, after last glacial age, Holocene sea level rise to +5.6m(4,740±100yrs BP). At that time, various geomorphological features are considered to be formed.

• Journal of Cardiovascular Imaging
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• v.31 no.2
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• pp.98-104
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• 2023

BACKGROUND: We aimed to investigate left ventricular (LV) global longitudinal strain (GLS) in end-stage renal disease patients and its change after kidney transplantation (KT). METHODS: We retrospectively reviewed patients who underwent KT between 2007 and 2018 at two tertiary centers. We analyzed 488 patients (median age, 53 years; 58% male) who had obtained echocardiography both before and within 3 years after KT. Conventional echocardiography and LV GLS assessed by two-dimensional speckle-tracking echocardiography were comprehensively analyzed. Patients were classified into three groups according to the absolute value of pre-KT LV GLS (|LV GLS|). We compared longitudinal changes of cardiac structure and function according to pre-KT |LV GLS|. RESULTS: Correlation between pre-KT LV EF and |LV GLS| were statistically significant, but the constant was not high (r = 0.292, p < 0.001). |LV GLS| was widely distributed at corresponding LV EF, especially when the LV EF was > 50%. Patients with severely impaired pre-KT |LV GLS| had significantly larger LV dimension, LV mass index, left atrial volume index, and E/e' and lower LV EF, compared to mildly and moderately reduced pre-KT |LV GLS|. After KT, the LV EF, LV mass index, and |LV GLS| were significantly improved in three groups. Patients with severely impaired pre-KT |LV GLS| showed the most prominent improvement of LV EF and |LV GLS| after KT, compared to other groups. CONCLUSIONS: Improvements in LV structure and function after KT were observed in patients throughout the full spectrum of pre-KT |LV GLS|.

• Restorative Dentistry and Endodontics
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• v.49 no.3
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• pp.25.1-25.9
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• 2024

Objectives: This study aimed to evaluate the color stability and solubility of Biodentine and NeoPutty in contact with different irrigation solutions. Materials and Methods: Biodentine and NeoPutty were set in cylindrical molds with 7 mm diameter and 1.5 mm high and immersed in distilled water, 17% ethylenediaminetetraacetic acid (EDTA), 2% chlorhexidine (CHX), 9% 1-hydroxyethylidene 1,1-diphosphonate (HEDP), and 5% sodium hypochlorite (NaOCl) solutions for 24 hours. The color change was measured with a spectrophotometer. The solubility values were calculated as the mass loss was expressed as a percentage of the original mass using an analytical balance with 10^-4 g accuracy. Data were analyzed with Kruskal-Wallis followed by Mann-Whitney U tests, and 2-way analysis of variance test followed by Bonferroni corrections for pairwise comparisons for solubility and color stability with a 5% significance threshold, respectively. Results: Biodentine exhibited higher color changes compared to the NeoPutty contact with all solutions except distilled water (p < 0.05). Both hydraulic cements (HCs) showed higher discoloration values immersion in CHX followed by NaOCl. No statistically significant difference was found between Biodentine and NeoPutty regardless of irrigation solution in terms of solubility (p > 0.05). Solubility values were lower in the distilled water group compared to EDTA and CHX (p < 0.05). Conclusions: Tested HCs showed solubility and color changes at various rates. NeoPutty could be an appropriate material in aesthetic areas. The usage of HEDP as an irrigant solution can be considered suitable for various endodontic treatments due to its relatively lower solubility and discoloration values.

• Journal of the Korean Society for Nondestructive Testing
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• v.31 no.5
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• pp.487-493
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• 2011

Alpha fetoprotein(AFP), which is serological marker for hepatocellular carcinoma, was quantitatively measured by its normal concentration, 10 ng/ml, with a label-free piezoelectric microcantilever mass sensor. The principle of detection is based on changes in the resonant frequency of the piezoelectric microcantilever before and after target molecules are attached to it, and its resonant frequency is measured electrically using a conductance spectrum. The resonant frequency of the developed sensor is approximately 1.34 MHz and the mass sensitivity is approximately 175 Hz/pg. The sensor has high reliability as mass sensor by reducing the effect of surface stress on resonant frequency due to attached proteins. 'Dip and dry' technique was used to react the sensor with reagents for immobilizing AFP antibody on the sensor and detecting AFP antigen. The measured mass of the detected AFP antigen was 6.02 pg at the concentration of 10 ng/ml, and 10.67 pg at 50 ng/ml when the immunoreaction time was 10 min.

• Journal of Veterinary Clinics
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• v.31 no.4
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• pp.307-312
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• 2014

A 16-year-old female Shih-Tzu, weighing 5 kg, presented with clinical symptoms of abdominal distension and urinary and fecal incontinence. Abdominal palpation detected a large mass. According to the radiographic findings, the bladder had been moved to the umbilicus by the mass and a large abdominal mass was confirmed in the lower abdominal area. Ultrasonography indentified a large heterogeneous mass with heterogeneous parenchyma and a focal anechoic area in the lower abdominal area. The complete blood count abnormalities suggested thrombocytosis and mild neutrophilia, and the serum chemistry indicated an elevated alkaline phosphatase value. During laparotomy, a firm mass that measured $10.5{\times}9.6cm$ was found between the uterine cervix and urinary bladder. The urethra was embedded in the mass. A diagnosis of leiomyosarcoma was established based on histopathology and histochemistry. One week after surgery, urinary retention symptoms that did not appear to be related to mechanical obstruction presented suddenly, but they did not respond to several drug treatments, thus long-term conservative therapy was adopted. The urinary symptoms disappeared on day 27 and the patient started to void large quantities of urine in a smooth and frequent manner. This case report describes the serial changes in the patient's status and the response after surgical remove of the urethra embedding leiomyosarcoma.

• Journal of Korean Medicine for Obesity Research
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• v.20 no.1
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• pp.20-30
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• 2020

Objectives: The purpose of this study is to verify the effects of H Gambitang (GB-001) on body composition and basal metabolic rate in pre- and post-menopausal obese woman retrospectively. Methods: The study was conducted on 57 middle-aged obese women. They were divided into two groups; pre-menopausal obesity group (Pr-MOG; n=34) and post-menopausal obesity group (Po-MOG; amenorrhea was continued to 14~48 month, n=23) with no significant difference of age, height, body weight and body mass index. All subjects took herbal medicine 3 times a day, for 6 weeks during treatment period. The weight, height, body fat mass, skeletal muscle mass, and basal metabolic rate of all subjects were measured on first visit. The following measurements were repeated after 2 weeks (2nd), 4 weeks (3rd) and 6 weeks (4th) with Inbody 370 (Biospace) equipment to identify changes of body fat mass, skeletal muscle mass, and basal metabolic rate. Results are represented as mean and standard deviation. Results: Po-MOG showed significantly lower decrease rate in weight reduction on 2~6 weeks while significantly higher decrease rate in skeletal muscle reduction on 4~6 weeks. There were no significant differences between two groups in body fat reduction rate and basal metabolic increasing rate. Conclusions: H Gambitang (GB-001) can be used not only in Pr-MOG but in Po-MOG in weight loss although the effect can be lower in Po-MOG. To prevent skeletal muscle mass loss in Po-MOG, following study on adjusting dose and components of H Gambitang (GB-001) thought to be necessary.

• The Journal of Engineering Geology
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• v.33 no.4
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• pp.573-586
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• 2023

Joints or weak planes can induce anisotropy in the strength and deformability of fractured rock masses. Comprehending this anisotropic behavior is crucial to engineering geology. This study used plaster as a friction material to mold specimens with a single joint. The strength and deformability of the specimens were measured in true triaxial compression tests. The measured results were compared with three-dimensional numerical analysis based on the distinct element method, conducted under identical conditions, to assess the reliability of the modeled values. The numerical results highlight that the principal stress conditions in the field, in conjunction with joint orientations, are crucial factors to the study of the strength and deformability of fractured rock masses. The strength of a transversely isotropic rock mass derived numerically considering changes in the dip angle of the joint notably increases as the intermediate principal stress increases. This increment varies depending on the dip of the joint. Moreover, the interplay between the dip direction of the joint and the two horizontal principal stress directions dictates the strength of the transversely isotropic rock mass. For a rock mass with two joint sets, the set with the steeper dip angle governs the overall strength. If a rock bridge effect occurs owing to the limited continuity of one of the joint sets, the orientation of the set with longer continuity dominates the strength of the entire rock mass. Although conventional three-dimensional failure criteria for fractured rock masses have limited applicability in the field, supplementing them with numerical analysis proves highly beneficial.

• Journal of Ginseng Research
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• v.38 no.2
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• pp.97-105
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• 2014

Background: Understanding what causes changes in the flux of free fatty acids (FFA) is important to elucidate the etiology of metabolic syndrome. The first aim of this study was to test whether or not hormones and the autonomic nervous system influence blood FFA levels. A secondary aim was to test by means of a multiple group path analysis whether the consumption of fermented red ginseng (FRG; Panax ginseng) would influence those causal relationships. Methods: Ninety-three postmenopausal women (age 50e73 yr) were randomly divided into two groups. One group (44 women; age, $58.4{\pm}5.9yr$; body mass index, $3.6{\pm}2.5kg/m^2$) was supplied place capsules and the other group (49 women, age $58.4{\pm}5.5yr$; body mass index, $22.9{\pm}2.4kg/m^2$) was supplied FRG capsules. Both prior to and after the study (2 wk), blood samples were collected from the participants and several blood variables were measured and analyzed. Results: Squared multiple correlations of FFA were 0.699 in the placebo group and 0.707 in the FRG group. The unstandardized estimate of estradiol (E2) for FFA was 0.824 in both groups. Conclusion: The path coefficients of cortisol and the branchial pulse for FFA were significantly different between the FRG group and the placebo group.

• Bulletin of the Society of Naval Architects of Korea
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• v.21 no.1
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• pp.21-34
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• 1984

This paper is concerned with the experimental investigation of transverse vibration characteristics in water of rectangular plates having an inner free cutout. Systematic experiments are carried out to investigate effects of the surrounding water on the added mass and the natural frequency of the plates due to the changes of the aspect ratio, hole size and eccentricity. The main subject is the clamped rectangular plate with a circular hole. For the purpose of comparative evaluations, some other common-type boundary conditions and hole shapes such as ellipses and rectangles are also investigated. Some of the results obtain are as follows; 1) For each given aspect ratio of the plate, there is a hole area ratio which gives a minimum value of the nondimensional frequency parameter for each mode. The hole area ratio increases as the order number of the mode increases. 2) The nondimensinal mass-increment parameter decreases as the aspect ration or the order number of the mode increases. For each given aspect ratio, the parameter the fundamental mode decreases monotonically as the hole area ratio increase. In cases of the second and higher order modes, however, each mode has a hole area ratio which gives a maximum value of the parameter for each aspect ratio more then 2/3. 3) Comparing elliptic holes with rectangular ones with same hole area ratio, nondimensional frequency parameters are almost same for each given ratio of the shorter axises to the longer one. 4) The influences of difference in boundary condion on nondimensional frequency parameters in water are similar to those in air.

• Journal of computational fluids engineering
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• v.8 no.2
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• pp.16-23
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• 2003

A numerical study of the mixing of two fluids(pure water and a solution of glycerol in water) in a microchannel was carried out. By varying the glycerol content of the glycerol/water solution, the variation in mixing behavior with changes in the difference of the properties of the two fluids(e.g., viscosity, density, diffusivity) was investigated. The mixing phenomena were tested for three micromixers: a square mixer, a three-dimensional serpentine mixer, and a staggered herringbone mixer. The governing equations of continuity, momentum and solute mass fraction were solved numerically. To evaluate mixing performance, a criterion index of mixing of mixing uniformity was proposed. In the systems considered, the Reynolds numbers based on averaged properties were 1 and 10. For low Reynolds number (Re = 1), the mixing performance varied inversely with mass fraction of glycerol due to the dominance of molecular diffusion. The mixing performance by diffusion deteriorated due to a significant reduction in the residence time of the fluid inside the mixers.