• 식품기술
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• 제15권2호
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• pp.3-24
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• 2002

펩타이드와 단백질은 전사, 번역, 후번역 단계에 걸친 모든 생물학적 반응을 조절한다. 그러나 분자수준에서 구조와 기능에 대한 우리의 이해는 초보적인 수준이다. 구조와 기능의 연관성에 대한 문제는 펩타이드와 단백질 자체에 대한 것과는 좀 다르다는 것을 명확히 할 필요가 있다. Multidomain을 갖는 단백질은 작고 통합적이며, 구조적으로 제한된 부분으로 쪼개는 것은 천연 단백질의 활성을 모방하여 저분자의 nonpeptide를 설계하는데 있어서 주요한 일이다. 결정적인 역할을 수행하는 domain을 모방하는 것은 특이성과 치료 효과에 있어서 자연적으로 얻어지는 단백질 물질과 비교하여 이로운 특성을 갖을 수 있고 분자 인지 분야에 관한 연구에 유용한 단서를 제공한다(Chen etal., 1992). 한편 펩타이드는 환경에 의해 구조가 심하게 영향을 받아 특성이 쉽게 변한다(Marshall et al., 1978). 수용액 내에서 이러한 구조적 유동성 때문에 그들이 결합할 수용체나 생리활성을 띄는 구조를 결정하는 것은 어렵고 복잡한 일이다(Fauchre,1987; Hruby, 1987). 구조를 한정하면 이러한 결정을 매우 쉽게 할 수 있다(Hrubyet al., 1987). 단백질 모방학은 분자지각 연구에 강력한 수단이며, 복잡한 단백질과 펩타이드의 구조-기능관계를 탐구하고 분석하는데 독특한 방법이다. 이 장에서는 매우넓고 빠르게 확장되고 있는 Peptidomimetic연구를 간략히 소개하고 있다. 단 본문은 기술 범위를 N-Methylated 아미노산과 스테로이드 등으로 제한하여 소개한다.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2007년도 학술발표회 논문집
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• pp.311-315
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• 2007

본 연구에서는 칼만필터(Kalman filter) 개념을 도입한 추계학적 편차보정 기법을 활용하여 실시간으로 레이더 및 관측강우에 대한 불확실성을 줄일 수 있는 레이더 최적강수 산정기법 개발에 관한 연구를 수행하였다. 개발된 레이더 강우량 추정기법은 한강유역을 대상으로 적용되었으며, 여기서 사용된 레이더 자료는 기상청에서 수집한 레이더 합성 CAPPI(Constant Altitude Plan Position Indicator) 자료이다. 자료기간은 2004년 7월 및 2006년 7월의 각 한달치 10분 간격의 레이더 자료가 사용되었고, 본 기간에 대응하는 약 130여개 지점의 기상청 AWS(Automatic Weather Station) 강우 관측자료가 편차보정을 위해 사용되었다. 매개변수별 편차추정 분석을 수행한 결과, 한강유역의 주어진 자료기간에 대한 적절한 편차추정을 위해 N=10, $i_T=2mm/h$의 매개변수를 선정하여 레이더 강수추정 오차에 대한 편차를 계산하여 개발 보정기법을 적용하였다. 그 결과 본 연구에서 개발한 추계동역학적 편차보정 기법은 Marshall-Palmer 기법의 높은 편차를 1에 가깝게 줄일 수 있는 것으로 나타났고, 홍수기 급박한 재해상황에서 보다 신속히 레이더 강수장을 제공할 수 있는 현업적 보정기법으로써의 유용성이 매우 높은 것으로 평가되었다.

• World Technopolis Review
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• 제3권3호
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• pp.122-138
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• 2014

The number of environment-related technologies has increased remarkably over the past two decades, as has the public's interest in effective resource use and ways to reduce the effects of global warming. Industries that are based on environment-related technologies are thus growing rapidly. Previous studies revealed that externalities derived from the population concentration in urban areas positively affect agglomerations of high-tech industries. Such externalities have been named the "knowledge spillover effect". The purposes of the present paper are to (1) give a thumbnail sketch of the locations of environment-related industries around the world, using the Organisation for Economic Co-operation and Development environment-related patent statistics, and (2) explicate the effects of the Marshall-Arrow-Romer (MAR) and Jacobs externalities, which result from population concentrations in urban areas, on the agglomeration of environment-related industries in Sweden. The analysis revealed that environment-related industries are located chiefly in urban areas across the globe, and that only the MAR externalities influenced positively on the agglomeration of these industries in Sweden.

• 한국초지조사료학회지
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• 제18권1호
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• pp.35-42
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• 1998

Eleven Italian ryegrass cultivars were examined for their genetic polymorphisms and phylogenetic relationships using randomly amplified polymorphic DNA (RAPD) markers. In RAPD analysis of 34 random primers, 96 of total 162 bands obtained from 16 primers were polymorphic and sizes of polymorphic band ranged between 0.5 and 1.5kb. Number of bands amplified per primer was varied from 3 to 16 and average number was 14.8. Phylogenetic relationship among cultivars based on the RAPD analysis was examined using UPGMA computer program. In pairwise genetic similarity test of 11 Italian ryegrass cultivars, Grazer and Orlando showed highest coefficient of genetic similarity as 0.740, whereas Marshall and Orlando was lowest as 0.438. Eleven Italian ryegrass cultivars were grouped into 3 major clusters and genetic distance of clusters ranged between 0.567 and 0.646, indicating low level of genetic variation.

• 한국수의병리학회:학술대회논문집
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• 한국수의병리학회 2005년도 Proceedings of The 2nd Asian Society of Veterinary Pathology Symposium(Vol.2) and 2005 Annual Meeting of The Korean Society of Veterinary Pathology(Vol.9)
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• pp.91-91
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• 2005

• 한국농공학회:학술대회논문집
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• 한국농공학회 1999년도 Proceedings of the 1999 Annual Conference The Korean Society of Agricutural Engineers
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• pp.313-318
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• 1999

This study is basic research to improve quality of asphalt concrete mixture, to preserve environment, and to recycle waste vinly. The mixing method and proper content of waste vinyl were determined through preliminary mix design. This study performed mix designs using 2 type gradations of aggregate in addtion content of wate vinly. Marshall stability at optimum asphalt content of asphalt concrete mixture addtin wate vinly was satisfied with the specification of the Ministry of Construction and Transportation , and its values indicated that dense grade asphalt concrete mixture containing waste vinyl were higher than common dense grade mixture (control). From this study, it was confirmed that addtion of waste vinyl improved quality of asphalt concrete mixture.

• Animal cells and systems
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• 제2권2호
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• pp.165-176
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• 1998

Seasonal changes in microzooplankton abundance were identified in the mesohaline Chesapeake Bay and several tributaries from July 1992 through December 1995. Ciliates numerically dominated, comprising over 90% of the total microzooplankton density and aloricate ciliates usually outnumbered loricate ciliates. Copepod nauplii accounted for the highest microzooplankton biomass (>75% in dry weight). Rotifers made small contributions to the total microzooplankton density and biomass (<5%). Time series analysis indicated a twelve month cycle in microzooplankton abundance, and mid-summer(August) peaks for copepod nauplii, and a spring through fall peaks (May-October) for ciliates. Rotifers showed two seasonal peaks: one in mid-summer(August) at the river stations and the other in mid-winter(February) at the mesohaline stations. Seasonal peaks of copepod nauplii and rotifers coincided with the mesozooplankton abundance peak. On the other hand, ciliate maximum usually occurred between the phytoplankton and mesozooplankton peaks. This pattern of microzooplankton seasonality suggests the intermediate trophic role of microzooplankton (especially ciliates) between the phytoplankton(especially picophytoplankton) and mesozooplankton in Chesapeake Bay and its tributaries.

• 천문학회보
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• 제43권2호
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• pp.56.3-56.3
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• 2018

We proceed to develop the control software of GMACS, which is a wide-field, multi-object, moderate-resolution optical spectrograph for the Giant Magellan Telescope (GMT). Flexure Compensation System (FCS) prototype is one of the electronics and mechanical prototypes for GMACS. In this poster, we present the software design for the FCS prototype by using the software system modeling language, SysML. We also show two development tools to control the prototype that communicates via EtherCAT: using TwinCAT and Visual C++ on Windows 10, and GMT Software Development Kit (SDK) and C++ on Linux. We discuss the way to design the GMACS control software, which would not depend on the development tools.

• 호남수학학술지
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• 제43권4호
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• pp.641-653
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• 2021

Armstrong enumerated the number of Fuss-Catalan paths with a given type and Rhoades provided the number of Dyck paths with a given type and a given number of blocks. In this paper we generalize those results to enumerate the number of Fuss-Catalan paths with a fixed type and a fixed number of blocks. We provide two proofs of this result. The first one uses the Chung-Feller theorem and a certain polynomial, while the second one is bijective. Also, we give a conjecture generalizing this result to the family of small Fuss-Schröder paths.

• 천문학회보
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• 제44권2호
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• pp.35.2-35.2
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• 2019

The next decade will see great advances in ground-based spectroscopic observing capabilities: facilities that are under development today will have larger collecting areas and greater spectroscopic multiplexing capabilities than ever before, and are sure to revolutionize the scientific productivity of our field. In this talk I will review the status of two of these next-generation facilities, the Giant Magellan Telescope's wide-field multiobject optical spectrograph, GMACS, and the Maunakea Spectroscopic Explorer project, a massively multiplexed spectroscopic facility currently under development in Hawaii that features an 11.25m diameter primary mirror which feeds 4,332 fibers and a suite of low- and high-resolution spectrographs. These two projects are scientifically quite complementary and both present exciting instrument development opportunities over the next few years.