• Animal cells and systems
• /
• 제12권2호
• /
• pp.97-100
• /
• 2008

A new marine sponge in the family Tethyidae, Tethya uljinensis n. sp. was collected from Uljin, Korea in 2007. Halicometes koreana in the family Tethyidae was redescribed. Tethya uljiensis n. sp. is closely to Tethya simi. in skeletal structure and spicule composition. But, it differs in the size of spicules(stronyloxea) and shape of oxyaster.

• 한국동물학회:학술대회논문집
• /
• 한국동물학회 1996년도 한국생물과학협회 국제학술대회
• /
• pp.72.2-72
• /
• 1996

No Abstract, See Full Text

• 한국해양바이오학회지
• /
• 제1권2호
• /
• pp.63-70
• /
• 2006

본 연구에서는 U937 인체 백혈병 세포의 증식에 미치는 PTX-2의 영향을 조사한 결과, PTX-2의 처리에 따라 U937 세포는 처리 농도 및 처리 시간 의존적으로 심한 형태적 변형과 함께 증식이 억제되었다. 이러한 PTX-2 처리에 의한 U937 세포의 증식억제는 apoptosis 유발과 관련이 있었으며, 이를 DAPI staining에 의한 apoptotic body 형성, flow cytometry를 이용한 sub-G1 세포 빈도의 정량적 분석을 통하여 확인하였다. 이러한 PTX-2 처리에 의한 U937 세포의 apoptosis 유발은 Bcl-2 family에 속하는 anti-apoptotic 인자인 Bcl-$X_L$의 발현 감소 및 IAPs family에 속하는 유전자들의 선택적 발현 감소와 연관성이 있음을 알 수 있었다. 이상의 결과들은 인체 암세포에서 PTX-2의 항암작용을 이해하는데 중요한 자료가 될 것이고 나아가 PTX-2을 포함한 그와 유사한 항암제 후보물질들의 연구에 있어서 기초 자료로서 사용될 수 있을 것으로 생각된다.

• 한국수산과학회지
• /
• 제48권1호
• /
• pp.1-15
• /
• 2015

Tissue engineering is an emerging, innovative technology to improve or replace the biological functions of damaged tissues and organs. Scaffolds are important materials for tissue engineering as they support cell attachment, migration, and differentiation. Marine sponges naturally contain scaffolds formed by extracellular matrix proteins (collagen and sponging) and strengthened by a siliceous or calcium carbonate skeleton. Coral skeletons are also derived naturally formed by essential calcium carbonate in the form of aragonite, and are similar to human bone. In addition, collagen extracted from jellyfish is a biosafe alternative to bovine and porcine collagen and gained attention as a potential source for tissue engineering. Moreover, cuttlefish bone is an excellent calcium source and can be used to generate bio-synthetic calcium phosphate. It has become a natural candidate for biomimetic scaffolds. This review describes the use of natural products derived from marine invertebrates for applications in bone tissue engineering based on studies from 2008 to 2014.

• Ocean and Polar Research
• /
• 제22권1호
• /
• pp.37-43
• /
• 2000

Epiphytic communities on marine plants of Seychelles (Indian Ocean Island group associated with East Africa) were investigated in January - March of 1989 during the $15^{th}$ biological voyage of the research vessel cademic Alexander Nesmeyanov. A seagrass species, Thalassodendron ciliatum, and macroalgae (Sargassum spp. and Halimeda spp.) were tested for host substrates and biomass of their dominant epiphytes were assessed. Also, in order to understand the effect of shading and nutrient filtering by epiphytes, two series of photosynthetic rates were compared for Th. ciliatum host leaves having 10% and no epiphytes. Total of 84 species of algae and main taxons of benthic animals were identified from three different host plants. An average biomass of the epiphytes on Th. cihiatum was $184.6g\;kg^{-1}$ and dominant species were green alga Halimeda opuntia, red algae Dictyurus occidentalis and Gelidiella myrioclada. These dominant species and their biomass were remarkably varied with depth increment. On Sargassum spp., an average biomass of the epiphytes was $0.18g\;kg^{-1}$ and the maximum biomass was never exceeded $0.16g\;kg^{-1}$. In the case of Halimeda spp. an average biomass of the epiphytes was $8.0g\;kg^{-1}$, and dominant species were Peyssonnelia dubyi, sponges and decapods. Photosynthetic rates of Th. ciliatum were significantly reduced in the leaves having 10% epiphytes (1.72 times lower, t=6.718, p<0.001).

• 한국해양바이오학회지
• /
• 제7권2호
• /
• pp.42-51
• /
• 2015

The community structure of cultivable bacteria associated with the marine sponge, Petrosia corticata, collected from Jeju Island in summer (September) of 2012 and winter (January) of 2013, were compared by the PCR-ARDRA method. Bacterial strains were cultured for 4 days at $26^{\circ}C$ on Zobell medium and marine agar medium. After PCR amplification of 16S rRNA gene of individual strains, the restriction enzymes MspI and HaeIII were used to make restriction patterns. As a result, 24 ARDRA patterns from the summer sponge and 20 ARDRA patterns from the winter sponge were obtained. The sequencing result of 1-3 selected strains from each pattern showed over 98% similarities with the known sequences from the public database. At the phylum level, the bacterial community structures of both sponges (summer and winter) were identical qualitatively and composed of 4 phyla : Proteobacteria, Actinobacteria, Bacteroidetes, and Firmicutes. Alphaproteobacteria accounted for 42.5% of total in summer sponge and 25.2% in winter, decreasing in the winter sample. Gammaproteobacteria accounted for 27.5% of total in summer sponge and 35.2% in winter, increasing in the winter sample. At the genus and species level, summer sponge had more diverse bacterial communities than winter sponge. Actinobacteria, Bacteroidetes, and Firmicutes increased in the winter sample.

• Journal of Microbiology and Biotechnology
• /
• 제26권11호
• /
• pp.2006-2011
• /
• 2016

The marine sponges Hyrtios and Haliclona species, both of which are known to produce secondary bioactive metabolites, were used to extract 1304KO-327 and 1304KO-328. Such secondary metabolites are potentially antibacterial, antiviral, anti-inflammatory, antitumoral, antifungal, and antiplasmodial. In the present study, the effects of 1304KO-327 and 1304KO-328 were studied for their clinical and pathological importance. The cytotoxicity of 1304KO-327 and 1304KO-328 was assessed via MTT(3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay on HT-29, Caco-2, and Raw 264.7 cells. Rotavirus-infected Caco-2 cells were used to prove the antiviral effects of the marine sponge extracts. The test results cogently proved that the virus-inhibiting effects of the sponge extracts improved with extract concentration. Anti-inflammatory effects of the marine sponge extracts were tested on Lipopolysaccharide-treated Raw 264.7 cells. Nitric oxide and cytokine were produced by treatment of the cells with LPS and the inhibiting effects of the sponge extracts on $IL-1{\beta}$ formation were investigated. This study found that the NO production was decreased dose dependently, and $IL-1{\beta}$ formation was significantly reduced by the marine sponge extracts.

• Animal Systematics, Evolution and Diversity
• /
• 제21권2호
• /
• pp.243-250
• /
• 2005

2000년 7월부터 2005년 5월까지 울릉도와 추자도에서 SCUBA 다이빙으로 채집된 해면동물을 동정$\cdot$분류한 결과 깃해면속(Mycale)의 2종 죽도깃해면[Mycale (Aegogropila) jukdoensis n. sp.]과 추자깃해면[Mycale (Mycale) chujaensis n. sp.)이 신종으로 밝혀졌다. 죽도깃해면은 M. grandis와 골편의 구성에서는 유사하지만 시그마체와 라피드가 M. grandis의 것보다 크고, 두 종류의 준아령침상체를 가진다. 또한 죽도깃해면의 이조상체 I은 M. grandis의 것보다 작다. 추자깃해면은 M. sulgata와 성장형태와 미소골편의 크기가 매우 유사하지만, 추자깃해면은 두 종류의 준아령침상체를 갖는 대신 M. sulgata는 단지 한 종류를 갖는다.

• Ocean and Polar Research
• /
• 제29권3호
• /
• pp.273-282
• /
• 2007

For an efficient management and utilization of marine biodiversity information, we made an attempt to develop the Korea Marine Biodiversity Information System (KoMBIS), building a species name inventory of Korea marine organisms. The inventory includes 17 organism groups: phytoplankton, zooplankton, algae and halophyte, sponges, cnidarians, rotifers, nematodes, bryozoans, brachiopods, molluscs, echiurans, annelids, arthropods, echinoderms, urochordates and fish. The species names were collected from 37 different references and reviewed for validity by taxonomists, which resulted in 9,798 valid names in addition to 1,845 synonyms. The Korea marine species inventory is the first one of this kind, for previous Korean species name inventories were mostly composed of terrestrial and freshwater organisms. KoMBIS, the information system developed, contains not only the species name but also information on morphological and ecological characteristics such as distribution, DNA barcode, and references. This system is convenient for the inputting of new data and servicing users through the internet, so that management and utilization of the biodiversity information is more efficient. Linking the DNA barcode data with species information provides an objective measure for identification of a species, which accommodates the recommendation of Consortium for the Barcode of Life, and makes the Korea marine biodiversity information compatible with international databases. Considering the frequent exchange of marine organisms internationally via ballast water and such issues as climate change, this information system will be useful in many areas of marine biodiversity.

• Animal Systematics, Evolution and Diversity
• /
• 제5권1호
• /
• pp.33-58
• /
• 1989

한국산 일축해면류를 연구하기 위해 삼면 연안과 16개 도서지방에서 1987년부터 1988년 8월까지 채집한 표본과 그동안 한남대학교 생물학과에 미해결종으로 보관되어있던 표본들을 동정, 분류한 결과 12과 21속 41종이 분류되었고 이중 13종은 한국미기록종이고 2종은 신종이었다. 한국미기록종과 신종에 대하여는 특기 또는 기재와 도판을 첨가하였다.