• Korean Journal of Health Education and Promotion
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• v.10 no.2
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• pp.73-85
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• 1993

It is necessary to understand the relationship between socio-cultural elements and smoking, alcohol, and marijuana use behaviors in order to plan public health policy or health promotion program of Mexican Americans. Demographic, socioeconomic status, and acculturation are variables which reflect mechanisms socialization influences these behavior patterns among this population. Thus, this study investigates the prevalence of addictive behaviors and individual differences on addictive behaviors related to variables of acculturation, age, gender, education, and income. And the interrelations among addictive behaviors are also examined. The analyses used data for Mexican Americans from the U.S. Hispanic Health and Nutrition Examination Survey conducted from July 1982 through December 1984 by the National Center for Health Statistics. ANOVA and correlation coefficients were used for this study. This study found that there are gender differences among addictive behaviors in their prevalence. Both males' and females' alcohol and marijuana use behaviors are positively related to the acculturation. Females' smoking behavior is positively related to acculturation while males' smoking is negatively related to it. Income and education are negatively related to males' smoking and positively related to males' alcohol behavior. However, males' marijuana behavior is not related to income. Females' smoking behaviors is not significantly related income and education. Education and income are positively related to marijuana behavior among females. Age is related to all three addictive behaviors among both gender. Age is negatively related to both males' and females' marijuana use behavior. Interrelation between smoking and marijuana use behavior is not significant among males. However, interrelations between alcohol and marijuana use behavior and between alcohol and smoking are significant among both genders. Females' smoking and marijuana use behavior is also significantly related.

• Journal of the Korea Convergence Society
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• v.10 no.11
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• pp.463-470
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• 2019

Currently, the consumption process of Medical Marijuana is complicated, so it is necessary to provide patient-centered services. This study defined the consumption process of Medical Marijuana as three steps and five procedures for the user-centered consumption process direction study, and created a consumption journey map through user interviews with experience of purchasing Medical Marijuana to find the pain point in the consumption process. Then, based on the case studies of the United States and Canada, three scenarios applicable to Korea were presented according to the scope of implementation. It is meaningful that it is a user-centered study based on the experience of Medical Marijuana consumers and it is expected to be used as reference data in improving the consumption process in the future.

• Archives of Pharmacal Research
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• v.28 no.12
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• pp.1365-1375
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• 2005

The antiestrogenic effects of marijuana smoke condensate (MSC) and three major cannabinoids, i.e., $\bigtriangleup^{9}$-tetrahydrocannabinol (THC), cannabidiol (CBD), and cannabinol (CBN), were evaluated using in vitro bioassays, viz., the human breast cancer cell proliferation assay, the recombinant human estrogen receptor (ER) competitive binding assay, and the reporter gene assay. The inhibitory effects on estrogen were also examined using the ethoxyresorufin-O­deethylase (EROD) assay, the aromatase assay, and the 17$\beta$-estradiol ($E_{2}$) metabolism assay. The results showed that MSC induced the antiestrogenic effect via the ER-mediated pathway, while THC, CBD, and CBN did not have any antiestrogenic activity. This suggests that the combined effects of the marijuana smoke components are responsible for the antiestrogenicity of marijuana use. In addition, MSC induced the CYP1A activity and the $E_{2}$ metabolism, but inhibited the aromatase activity, suggesting that the antiestrogenic activity of MSC is also related to the indirect ER-dependent pathway, as a result of the depletion of the in situ $E_{2}$ level available to bind to the ER. In conclusion, pyrogenic products including polycyclic aromatic hydrocarbons (PAHs) in the non-polar fraction, which is the most biologically active fraction among the seven fractions of MSC, might be responsible for the antiestrogenic effect.

• Journal of The Korean Society of Clinical Toxicology
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• v.18 no.1
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• pp.47-50
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• 2020

A 21-year-old female patient complaining of hemiparesis was diagnosed with right middle cerebral artery infarction. No risk factor was found, despite an extensive young-age stroke work-up, except her history of marijuana use. The patient had smoked marijuana for treating depression for more than five years. Magnetic resonance angiography showed multifocal intra- and extracranial stenoses, suggesting cannabinoid-induced vasculopathy. Since the use of illicit drugs has increased nationwide, physicians should consider it as a possible cause of a stroke due to an unknown etiology.

• Journal of the Korea Convergence Society
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• v.11 no.5
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• pp.131-138
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• 2020

Service industry has become the most important industry among various economic activities. These rapid changes have made the business environment more integral and important to balance the interests of various stakeholders. However, when a new service enters South Korea, there is a need to establish an identity that helps the various stakeholders to have a consistent understanding because different stakeholders have different understandings about the service. This paper is a study on the application of the optimized identity to the medical Marijuana service and the implementation plan. It consists of three steps: theoretical consideration, development of the optimization identity structure, and application to the medical Marijuana service.

• Proceedings of the PSK Conference
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• 2000.10a
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• pp.95-99
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• 2000

• Investigative Magnetic Resonance Imaging
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• v.22 no.3
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• pp.168-171
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• 2018

Cannabis or marijuana is the most commonly used recreational drug after alcohol in the world, and usage is generally recognized as having few serious adverse effects. However, usage is restricted in South Korea. The report of ischemic stroke associated with cannabis is rare in literature. We present a case of a 47-year-old female patient with no underlying disease presenting with acute ischemic stroke after smoking cannabis in South Korea. The result for synthetic cannabinoid metabolites (delta-9 tetrahydrocannabinol) screening was positive. Absence of other vascular risk factors and drug screening results suggest a causal role of cannabis in this ischemic stroke case. The patient eventually progressed to brain death. The underlying mechanism, clinical manifestation, and imaging findings of cannabis-related stroke will be reviewed.

• YAKHAK HOEJI
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• v.52 no.3
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• pp.172-175
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• 2008

Stable isotope ratio of carbon and nitrogen ($\delta^{13}C$ & $\delta^{15}N$), and $\Delta^{9}$-tetrahydrocannabinol (THC) contents were measured on 37 Korean cannabis and 10 commercial grade marijuana seized in Korea. Factors influencing on the measured values and their variations were investigated. $\delta^{13}C$ value of cannabis is specified mainly by water availability. Korean cannabis showed relatively low $\delta^{13}C$ values ranging -33.29$\sim$-27.01% (mean=-31.01%), which reflect geographic conditions of Korea where is rainy, especially during summer. $\delta^{15}N$ values, which reflect individual planting conditions, were relatively high up to -0.5$\sim$18.0% (mean=6.44%). It reflects characteristics of Korean cannabis growing wild in forest or cultivated in fertile soil. Tetrahydrocannabinol is the major hallucinogenic compound of cannabis. Ethanol extracts of cannabis leaves were derivatized by N,O-bis(trimethylsilyl)trifluoroacetamide (BSTFA), and the derivatives were analyzed by GC-MS in selected ion monitoring (SIM) mode. THC contents of Korean cannabis ranged 0.11$\sim$4.34% (mean=1.47%), which were relatively low compared with commercial grade marijuana.

• Journal of Periodontal and Implant Science
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• v.54 no.4
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• pp.224-235
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• 2024

Purpose: This systematic review investigated whether drug use is associated with the presence of oral lesions and periodontitis. Methods: A search was performed for studies that analyzed the presence of periodontitis and/or oral lesions in users of crack, cocaine, and/or marijuana in the PubMed, Scopus, and Web of Science databases. Observational studies in English, Spanish, or Portuguese, without limitation of year, age, and sex, were included. Studies that did not evaluate periodontitis and oral lesions according to the eligibility criteria were excluded. Two authors independently performed study selection and data extraction using a standardized form. The risk of bias of studies included in the meta-analysis was assessed using the Joanna Briggs Institute Critical Appraisal Checklist. The meta-analysis included studies that investigated the association of drug use with the outcome. Results: The initial search resulted in 9,279 articles, from which 16 studies with 15,434 participants were included in the review and 8 studies were included in the meta-analysis. Most studies that evaluated periodontitis in drug users and non-users found a positive association in users. Most studies that analyzed oral lesions reported a higher prevalence, association, or risk of oral lesions in drug users than in non-users. A critical evaluation identified a need to improve the control and reporting of confounding factors in studies on this topic. An association was found between periodontitis and the use of crack, cocaine, and/or marijuana (odds ratio [OR], 1.84; 95% confidence interval [CI], 1.04-3.27; P=0.04) and between oral lesions and the use of these drugs (OR, 2.13; 95% CI, 1.58-2.86; P<0.001). Conclusions: Drug users are more likely to develop oral lesions and periodontitis than nonusers. However, the results should be interpreted with caution, considering the heterogeneity and quality of the studies included in the analysis.

• Communications for Statistical Applications and Methods
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• v.7 no.3
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• pp.711-720
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• 2000

A case study of modeling ordinal categorical response data with the MARS method is done. The study is to analyze the effect of some personal characteristics and socioeconomic status on the teenage marijuana use. The MARS method gave a new insight into the data set.