DOI QR코드

DOI QR Code

Ischemic Stroke after Use of Cannabis: a Case Report and Review of Literature

  • Jung, Jo Sung (Department of Radiology, Soonchunhyang University College of Medicine) ;
  • Park, Yae Won (Department of Radiology, Ewha Womans University College of Medicine) ;
  • Lee, Seung Ah (Department of Neurology, Ewha Womans University College of Medicine) ;
  • Song, Tae Jin (Department of Neurology, Ewha Womans University College of Medicine) ;
  • Lim, Soo Mee (Department of Radiology, Ewha Womans University College of Medicine)
  • 투고 : 2018.07.10
  • 심사 : 2018.08.31
  • 발행 : 2018.09.30

초록

Cannabis or marijuana is the most commonly used recreational drug after alcohol in the world, and usage is generally recognized as having few serious adverse effects. However, usage is restricted in South Korea. The report of ischemic stroke associated with cannabis is rare in literature. We present a case of a 47-year-old female patient with no underlying disease presenting with acute ischemic stroke after smoking cannabis in South Korea. The result for synthetic cannabinoid metabolites (delta-9 tetrahydrocannabinol) screening was positive. Absence of other vascular risk factors and drug screening results suggest a causal role of cannabis in this ischemic stroke case. The patient eventually progressed to brain death. The underlying mechanism, clinical manifestation, and imaging findings of cannabis-related stroke will be reviewed.

키워드

참고문헌

  1. Singh NN, Pan Y, Muengtaweeponsa S, Geller TJ, Cruz- Flores S. Cannabis-related stroke: case series and review of literature. J Stroke Cerebrovasc Dis 2012;21:555-560 https://doi.org/10.1016/j.jstrokecerebrovasdis.2010.12.010
  2. Chung H, Park M, Hahn E, Choi H, Choi H, Lim M. Recent trends of drug abuse and drug-associated deaths in Korea. Ann N Y Acad Sci 2004;1025:458-464 https://doi.org/10.1196/annals.1316.056
  3. Ashton CH. Adverse effects of cannabis and cannabinoids. Br J Anaesth 1999;83:637-649 https://doi.org/10.1093/bja/83.4.637
  4. Vachhani P, Phipps M, Raghavan P. Recurrent extracranial internal carotid artery vasospasm associated with recreational marijuana use. Clin Imaging 2017;43:6-8 https://doi.org/10.1016/j.clinimag.2016.12.010
  5. Barber PA, Pridmore HM, Krishnamurthy V, et al. Cannabis, ischemic stroke, and transient ischemic attack: a case- control study. Stroke 2013;44:2327-2329 https://doi.org/10.1161/STROKEAHA.113.001562
  6. Wolff V, Lauer V, Rouyer O, et al. Cannabis use, ischemic stroke, and multifocal intracranial vasoconstriction: a prospective study in 48 consecutive young patients. Stroke 2011;42:1778-1780 https://doi.org/10.1161/STROKEAHA.110.610915
  7. Mateo I, Pinedo A, Gomez-Beldarrain M, Basterretxea JM, Garcia-Monco JC. Recurrent stroke associated with cannabis use. J Neurol Neurosurg Psychiatry 2005;76:435- 437 https://doi.org/10.1136/jnnp.2004.042382
  8. Finsterer J, Christian P, Wolfgang K. Occipital stroke shortly after cannabis consumption. Clin Neurol Neurosurg 2004;106:305-308 https://doi.org/10.1016/j.clineuro.2004.02.001
  9. Johnson S, Domino EF. Some cardiovascular effects of marihuana smoking in normal volunteers. Clin Pharmacol Ther 1971;12:762-768 https://doi.org/10.1002/cpt1971125762
  10. Uhegwu N, Bashir A, Hussain M, Dababneh H, Misthal S, Cohen-Gadol A. Marijuana induced reversible cerebral vasoconstriction syndrome. J Vasc Interv Neurol 2015;8:36- 38

피인용 문헌

  1. Harmful Effects of Smoking Cannabis: A Cerebrovascular and Neurological Perspective vol.10, pp.None, 2018, https://doi.org/10.3389/fphar.2019.01481