• Journal of the Korean Society of Costume
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• v.62 no.1
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• pp.120-136
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• 2012

This thesis takes an aim to investigate the relationship between the costume and enlightenment ideology by studying the change of costume, and reviewing the portraiture of Queen Marie Antoinette. The method of this research is to select the 29 pieces among the portraitures from 1770 to 1793, and to analyze the headdress, shape of robes and ornaments. The results are as follows. The first period(1770-1774): The costume in this period of Dauphin of France is described as vivid, and simple like her characters, and also represents her active lifestyle. The ideology of equality between the two sexes from the enlightenment slightly influence the costumes seen inside the portrait of Dauphin. The second period (1775-1779): This is the early period of the Queen's enthronement and also before her childbirth. The relatively small number of portraits showed her as an authoritative figure because her skirts were expanded with huge panier, the waist were tightened with corset, and her headdress was enlarged. Thus, this period could not be defined as the one of enlightenment philosophies in light of the persistent unsanitary construction of costumes distorting the body. The third period(1780-1789): There are many portraits depicting the Queen and her children. It is noteworthy that the English style picturesque garden was illustrated as a background while the costume was simple and sanitary, both being affected by the enlightenment. The last period(1789-1793): This is the period between the French revolution and the death of the Queen. The form of costumes was transformed into the neoclassic style, headdress was reduced in size, and was simplified as a result of complete change of costume for the enlightenment. This research is to be interpreted as a tool of study about the relationship of costume, society and ideological streams and also be a means of elucidating the contemporary times in view of the past ones.

• Journal of the Korean Operations Research and Management Science Society
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• v.27 no.4
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• pp.41-65
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• 2002

We study a multi-component production/inventory system in which individual components are made to meet various demand types. We assume that the demands arrive according to a Poisson process, but there is a fixed probability that a demand requests a particular kit of different components. Each component is produced by a flow line with several stations in which the processing times of each station follow a two-stage Coxian distribution. The production of each component is operated by an independent base-stock policy with blocking. We assume that the time needed to assemble final products follows a general distribution and the capacity of an assembling facility is sufficiently large. The objective of this study is to obtain key performance measures such as the distribution of the number of each orders for each final product and the mean time of fulfilling a customer order. The basic principle of the proposed approximation method is to decompose the original system into a set of subsystems, each subsystem being associated with a flow line. Each subsystem is analyzed in isolation using a Marie's method. An iterative procedure is then used to determine the unknown parameters of each subsystem. Numerical results show that the accuracy of the approximation method is acceptable.

• Molecules and Cells
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• v.23 no.1
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• pp.39-48
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• 2007

Charcot-Marie-Tooth (CMT) disease and hereditary neuropathy with liability to pressure palsies (HNPP) are frequent forms of genetically heterogeneous peripheral neuropathies. Reciprocal unequal crossover between flanking CMT1A-REPs on chromosome 17p11.2-p12 is a major cause of CMT type 1A (CMT1A) and HNPP. The importance of a sensitive and rapid method for identifying the CMT1A duplication and HNPP deletion is being emphasized. In the present study, we established a molecular diagnostic method for the CMT1A duplication and HNPP deletion based on hexaplex PCR of 6 microsatellite markers (D17S921, D17S9B, D17S9A, D17S918, D17S4A and D17S2230). The method is highly time-, cost- and sample-saving because the six markers are amplified by a single PCR reaction and resolved with a single capillary in 3 h. Several statistical and forensic estimates indicated that most of these markers are likely to be useful for diagnosing the peripheral neuropathies. Reproducibility, as determined by concordance between independent tests, was estimated to be 100%. The likelihood that genotypes of all six markers are homozygous in randomly selected individuals was calculated to be $1.6{\times}10^{-4}$, which indicates that the statistical error rate for this diagnosis of HNPP deletion is only 0.016%.

• Journal of Genetic Medicine
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• v.19 no.1
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• pp.7-13
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• 2022

Purpose: Preimplantation genetic testing for monogenic disorders (PGT-M) has been successfully used to prevent couples with monogenic disorders from passing them on to their child. Charcot-Marie-Tooth Disease (CMT) is a genetic disorder characterized by progressive extremity muscle degeneration and loss of sensory function. For the first time in Korea, we report our experience of applying single nucleotide polymorphism genotyping and karyomapping for PGT-M of CMT disease. Materials and Methods: Prior to clinical PGT-M, preclinical tests were performed using genotypes of affected families to identify informative single-nucleotide polymorphisms associated with mutant alleles. We performed five cycles of in vitro fertilization PGT-M in four couples with CMT1A, CMT2A, and CMT2S in CHA Fertility Center, Seoul Station. Results: From July 2020 through August 2021, five cycles of PGT-M with karyomapping in four cases with CMT1 and CMT2 were analyzed retrospectively. A total of 17 blastocysts were biopsied and 15 embryos were successfully diagnosed (88.2%). Ten out of 15 embryos were diagnosed as unaffected (66.7%). Five cycles of PGT-M resulted in four transfer cycles, in which four embryos were transferred. Three clinical pregnancies were achieved (75%) and the prenatal diagnosis by amniocentesis for all three women confirmed PGT-M of karyomapping. One woman delivered a healthy baby uneventfully and two pregnancies are currently ongoing. Conclusion: This is the first report in Korea on the application of karyomapping in PGT-M for CMT patients. This study shows that karyomapping is an efficient, reliable and accurate diagnostic method for PGT-M in various types of CMT diseases.

• Journal of Ecology and Environment
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• v.43 no.2
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• pp.183-190
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• 2019

Background: In the Philippines, the practice of planting mangroves over seagrass has been a practice done to promote coastline protection from damages done by storms. Despite the added protection to the coastline, the addition of an artificial ecosystem gradually inflicts damage to the ecosystem already established. In this study, seagrass communities that had no history of mangrove planting were compared with those that had mangrove planting. The percent substrate cover of seagrass in the sampling areas was determined, and the macroinvertebrates present in the sampling areas were also observed. The study was conducted based on reports of mangrove planting activity that disrupted seagrass functions on Santa Fe, Bantayan Island, Cebu. Transect-quadrat method sampling was done to assess the chosen sites. Results: Six species of seagrass was found on the site without mangrove planting which was barangay Ocoy (Cymodocea sp., Thalassia sp., Halodule sp., Enhalus sp., Halophila sp., and Syringodium sp.) and had a higher percent cover, while only four were found on the site with mangrove planting (barangay Marikaban). It was also found that barangay Marikaban had a lesser Shannon-Wiener and Simpson's index compared to barangay Ocoy. Jaccard's index of similarity between the two sites was low. Conclusion: With the results of the assessment, we recommend proper monitoring of future mangrove planting activities and that these activities should not disrupt another ecosystem as all ecosystems are important.

• Proceedings of the Korean Society of Tobacco Science Conference
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• 1999.10a
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• pp.9-12
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• 1999

Up to the 60's cigarette paper commercial grades were simply described as ' non combustible ', ' combustible ' or ' extra-combustible '. It was assumed that combustibility of the paper itself was correlated with cigarette combustibility. Since then, the characteristics of cigarette paper, like natural porosity and burning additives, which influence truly cigarette combustibility, have been described by various authors and it became clear to cigarette designers that paper combustibility was not generally a significant factor governing cigarette combustibility. On the other hand, for Roll Your Own(RYO)wrapping papers, the ECPCI has proposed to the CORESTA RYO Task Force to use paper combustibility, and specially the LCT test, to classify papers between low and high smoke delivery, and a new Task Force on PAPER COMBUSTIBILITY was recently set up to develop a recommended method. The objective of this presentation Is to show results demonstrating that for paper used on cigarettes, there is NO GENERAL CORTRELATION between PAPER and CIGARETTE combustibility. We will also show results confirming that, for the specific group of RYO booklet papers containing no burning additives, there is a correlation between paper combustibility and FCSA's Combustibility/smoke delivery. This apparent discrepancy will be explained by reviewing the role played by the various characteristics of cigarette paper in governing cigarette combustibility.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.4
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• pp.1791-1796
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• 2014

Background: Colorectal cancer (CRC) is a leading cause of cancer death among Vietnamese Americans, yet screening remains underutilized. We investigated the effectiveness of a culturally tailored DVD intervention in promoting CRC screening among unscreened Vietnamese Americans age 50 and over. Materials and Methods: Using a community-based participatory research approach, we conducted a trial comparing twenty-eight subjects who received a mailed DVD in Vietnamese, with twenty-eight subjects who received a mailed brochure in Vietnamese. Subjects completed telephone surveys at baseline, One-month, and one-year. The primary outcome was receipt of screening. Secondary measures were participants' knowledge, attitudes, and beliefs about CRC screening. Two focus groups explored the intervention's acceptability and effectiveness. Results: At one year, CRC screening rates of 57.1% and 42.9% were observed in experimental and control group respectively (p=0.42), Subjects in both groups showed increased knowledge about CRC after one month. Focus group findings revealed that the DVD was an effective method of communicating information and would help promote screening. Conclusions: The findings suggest that culturally tailored, linguistically appropriate content is more important than the type of media used. This relatively low intensity, low cost intervention utilizing a DVD can be another useful method for outreach to the often hard-to-reach unscreened population.

• Journal of Smart Tourism
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• v.4 no.2
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• pp.5-14
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• 2024

This study explores the transformative potential of machine learning (ML) and ML-driven data analytics in the hospitality industry. It provides a comprehensive overview of this emerging method, from explaining ML's origins to introducing the evolution of ML-driven data analytics in the hospitality industry. The present study emphasizes the shift embodied in ML, moving from explicit programming towards a self-learning, adaptive approach refined over time through big data. Meanwhile, social media analytics has progressed from simplistic metrics deriving nuanced qualitative insights into consumer behavior as an industry-specific example. Additionally, this study explores innovative applications of these innovative technologies in the hospitality sector, whether in demand forecasting, personalized marketing, predictive maintenance, etc. The study also emphasizes the integration of ML and social media analytics, discussing the implications like enhanced customer personalization, real-time decision-making capabilities, optimized marketing campaigns, and improved fraud detection. In conclusion, ML-driven hospitality data analytics have become indispensable in the strategic and operation machinery of contemporary hospitality businesses. It projects these technologies' continued significance in propelling data-centric advancements across the industry.