• Asian Pacific Journal of Cancer Prevention
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• 제14권11호
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• pp.6935-6940
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• 2013

Background: This study aimed to develop a prognostic model in patients with early-stage cervical squamous cell carcinoma based on clinicopathological features, including invasive margin characteristics. Materials and Methods: Clinicopathological features and outcomes of 190 patients with FIGO stage IB-IIA cervical squamous cell carcinoma treated by surgery were collected and analyzed for factors associated with tumor recurrence. In addition to well-recognized pathological risk factors, the pathological characteristics of invasive margin (type of invasive pattern and degree of stromal desmoplasia and peritumoral inflammatory reaction) were also included in the analysis. Multiple scoring models were made by matching different clinicopathological variables and/or different weighting of the score for each variable. The model with the best performance in the prediction of recurrence and decreased survival was selected. Results: The model with the best performance was composed of a combined score of invasive pattern, lymphovascular space invasion (LVSI), and degree of inflammatory reaction and stromal desmoplasia (total score =10). Compared to those with score ${\leq}8$, the patients with score 9-10 had a significantly higher recurrence rate in the overall group (p<0.001) and the subgroup without adjuvant therapy (p<0.001), while the significance was marginal in the subgroup with adjuvant therapy (p=0.069). In addition, the patients with score 9-10 had a higher rate of tumor recurrence at distant sites (p=0.007). The disease-free survival was significantly lower in the patients with score 9-10 than those with score ${\leq}8$ among the overall patients (p<0.001), in the subgroup without adjuvant therapy (p<0.001), and the subgroup with adjuvant therapy (p=0.047). Conclusions: In this study, a prognostic model based on a combination of pathological characteristics of invasive margin and LVSI proved to be predictive of tumor recurrence and decreased disease-free survival in patients with early-stage cervical squamous cell carcinoma.

• Restorative Dentistry and Endodontics
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• 제31권4호
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• pp.282-289
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• 2006

본 연구의 목적은 5급 복합레진 수복물에 각종 레진 전색제를 적용한 후, 수복물의 교합면측과 치은측 변연 미세누출에 대한 레진 전색제의 감소효과를 평가하기 위하여 시행하였다. 40개의 발거된 대구치의 협면 치경부에 5급 와동을 형성하고 복합레진을 충전한 후, 사용된 레진 전색제에 따라 다음 과 같이 4개의 군으로 분류하였다; 복합레진 표면과 변연부에 레진 전색제를 적용하지 않은 대조군, 복합레진 표면과 변연부에 각각 레진 전색제를 적용한 Fortify Plus 군, BisCover 군 및 PermaSeal 군으로 분류하였다. 각 군의 시편을 실온의 증류수에 24시간 동안 보관한 후, $5^{\circ}C$와 $55^{\circ}C$에서 1,000회의 열 순환을 시행하고 2% methylene blue 용액에 4시간동안 침적시켰다. 각 치아는 저속의 diamond disk 를 이용하여 각 수복물의 중앙부를 따라 협, 설 방향으로 양분 하고 20배율의 광학 입체현미경 하에서 각각 교합면측과 치은측 변연 미세누출을 평가하였다. 각 군의 교합면측과 치은측 변연 미세누출에 대한 유의성을 검정을 시행하여 다음과 같은 결과를 얻었다. 1. 교합면측 변연 미세누출은 사용된 레진 전색제 간에 통계학적으로 유의한 차이를 나타내지 않았다. 2. 치은측 변연 미세누출은 대조군과 Fortify Plus 군이 PermaSeal 군보다 통계학적으로 높게 나타났으며, 또한 Fortify Plus 군은 Biscover 군보다 통계학적으로 높은 변연 미세누출을 나타내었다 (p < 0.05). 3. 대조군과 Fortify Plus 군은 교합면측 보다 치은측 변연에서 통계학적으로 더 높은 미세누출을 나타내었다 (p < 0.05). 4. BisCover 군과 PermaSeal 군은 교합면측과 치은측의 변연 미세누출 간에 통계학적으로 유의한 차이를 나타내지 않았다. 본 연구를 종합하면, 5급 복합레진 수복물의 교합면측 변연 미세누출에 대한 레진 전색제의 감소효과는 크게 나타나지 않았지만, 치은측 변연 미세누출에 대한 레진 전색제의 감소효과는 사용된 레진 전색제에 따라 서로 다르게 나타났다.

• 한국공간구조학회논문집
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• 제18권2호
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• pp.121-128
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• 2018

The push-out tests have been conducted on the specimens which consist of the steel beam with U-shape section and the cap-type shear connectors with constant intervals. Existing equations for the evaluation of shear connector strength have been investigated on the basis of test results. The reinforcing bars for longitudinal reinforcement and the penetrative bars for transverse reinforcement didn't have much effect on the shear capacity of the cap-type shear connector. The larger the width of cap-type shear connector was profiled, the greater the shear strength turned. The shear capacities of cap-type shear connectors with constant intervals were evaluated on the basis of push-out test results, and those were possible to be determined with proper safety margin using the Eurocode 4. The slip capacity of cap-type shear connector was shown to exceed the limit value of 6mm for sufficiently ductile behavior.

• International Journal of Concrete Structures and Materials
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• 제18권2E호
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• pp.111-116
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• 2006

The purpose of this study is to investigate the relations between unbonded tendon stress and its influential parameters, i.e. bonded reinforcement ratio, span/depth ratio, and loading type. To this end, the influence of such parameters was examined with twenty eight test results of previous studies. Afterwards, an experimental study was carried out with twenty one test specimens. The investigation of previous and current experiments revealed the followings; (1) The bonded reinforcement ratio and prestressing ratio were proved to be important variables on the unbonded tendon stress. (2) The ratio of span to depth and the type of loading affected the unbonded tendon stress partially although their effects varied with bonded reinforcement ratio. (3) AASHTO LRFD Code and Moon/Lim's design equations predicted the experimental results well with the safety margin.

• 대한수의학회지
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• 제42권3호
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• pp.419-423
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• 2002

Postoperative suture granuloma have rarely been reported in animals. Eight biopsy masses from testes areas of neutralized dogs were diagnosed as suture granuloma. The suture granuloma occurred at any time from several weeks to a few years after surgery and appeared to be testicular tumors by macroscopic examination. The granulomas were classified into three types based on the histopathological findings. The first type of pyogranuloma was mainly composed of neutrophils, macrophages, and suture fragments. The second type was chronic necrotizing granuloma which was well demarcated by fibrous connective tissues and was composed of a few suture fragments, macrophages and central fibrinoid necrosis. The third type of granuloma had a poorly defined margin with scarcely observed suture fragments and central necrosis in the tissue. These histopathological findings suggested that various types of suture granuloma may be caused by suture material and could even appear long after surgery.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2001년도 춘계학술대회논문집
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• pp.744-749
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• 2001

As related to rotordynamics, dynamic characteristics of the wear ring seal in high pressure multi-stage pump is calculated in the cases of labyrinth, damper and helically grooved types. The. results show that the labyrinth seal type has superior performance in the view point of leakage. However, in terms of rotordynamics view point, the damper seal type gains acceptable separate margin in critical speed range, while it has slightly inferior leakage performance compared to labyrinth seal type.

• 보건의료산업학회지
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• 제8권2호
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• pp.1-10
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• 2014

This study examined nonpatient revenues of university hospitals in korea. The data source for this study was 22 university hospitals over the period 2010-2012. In this study, patient revenues, patient expenses, operating profit, nonpatient revenues, total revenues, operating margin, normal profit to gross revenues, ratio of the nonpatient revenues in the total revenues were analysed by the annual and three-year average. The analysis of nonpatient revenue differences by hospital type, bed size, location, management performance was performed by T-test and oneway ANOVA. The results were as follows. First, nonpatient revenues of university hospitals were increased during the period 2010-2012. Second, nonpatient revenues according to hospital type, bed size, location in the university hospitals had significant difference. Third, hospital type was significantly associated with normal profit to gross revenues which was profitability index about nonpatient revenues. Based on these results, this study suggests implications to diversify for management performance in hospitals.

• 한국원자력학회:학술대회논문집
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• 한국원자력학회 1997년도 춘계학술발표회논문집(1)
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• pp.335-341
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• 1997

The generic analysis method for core flow instability is suggested to confirm that the core flow instability would not occur on PWR conditions. For the confirmation, the stability criteria of each fuel type are provided. Instability investigations in various accident conditions prove that the locked rotor accident is the most limiting case to instability. Parametric Effects are surveyed and in good agreement with available studies. The effects of heat flux distribution become negligible as the subcooling number is decreased. The power margin to instability is calculated quantitatively in various accident conditions.

• 한국원자력학회:학술대회논문집
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• 한국원자력학회 1997년도 춘계학술발표회논문집(1)
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• pp.489-494
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• 1997

A comparative transient analyses were performed for oxide and nitride cores or a large (3000 MWt), pool-type, liquid-metal-cooled reactor (LMR). The study was focused on three representative accident initiators with failure to scram : the unprotected loss-of-flow (ULOF), the unprotected transient overpower (UTOP), and the unprotected fast transient overpower (UFTOP). The margins to fuel melting and sodium boiling have been evaluated for these representative transients. The results show that there is an increase in safety margin with nitride core which maintains the physical dimensions of the oxide core.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2005년도 ICCAS
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• pp.2183-2187
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• 2005

In this paper we propose a new fault detection and isolation (FDI) method for those faults of parameter change type. First, we design a residual generator based on the ${\delta}$-operator model of the plant by using the stable pseudo inverse system. Second, the parameter change is estimated by using the property of the block Hankel operator. Third, reliability with respect to stability is quantified. Fourth, the limitations for the meaningful diagnosis in our method are given. The numerical examples demonstrate the effectiveness of the proposed method.