• Journal of Gastric Cancer
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• 제11권3호
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• pp.162-166
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• 2011

Purpose: Endoscopic resection is widely accepted as standard treatment for early gastric cancer (EGC) without lymph node metastasis. The procedure is minimally invasive, safe, and convenient. However, surgery is sometimes needed after endoscopic mucosal resection (EMR)/endoscopic submucosal dissection (ESD) due to perforation, bleeding, or incomplete resection. We evaluated the role of surgery after incomplete resection. Materials and Methods: We retrospectively studied 29 patients with gastric cancer who underwent a gastrectomy after incomplete EMR/ESD from 2006 to 2010 at Korea University Hospital. Results: There were 13 incomplete resection cases, seven bleeding cases, three metachronous lesion cases, three recurrence cases, two perforation cases, and one lymphatic invasion case. Among the incomplete resection cases, a positive vertical margin was found in 10, a positive lateral margin in two, and a positive vertical and lateral margin in one case. Most cases (9/13) were diagnosed as mucosal tumors by endoscopic ultrasonography, but only three cases were confirmed as mucosal tumors on final pathology. The positive residual tumor rate was two of 13. The lymph node metastasis rate was three of 13. All lymph node metastasis cases were submucosal tumors with positive lymphatic invasion and no residual tumor in the gastrectomy specimen. No cases of recurrence were observed after curative resection. Conclusions: A gastrectomy is required for patients with incomplete resection following EMR/ESD due to the risk of residual tumor and lymph node metastasis.

• 한국추진공학회:학술대회논문집
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• 한국추진공학회 2004년도 제22회 춘계학술대회논문집
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• pp.380-384
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• 2004

A fuel spiking test was performed to measure the surge margin of the compressor in a gas turbine engine. During the test, fuel spiking signal was superimposed on the engine controller demand and the mixed signals were used to control a fuel line servo-valve. For the superimposition, a subsystem composed of a fuel controller and a function generator was used. During the fuel spiking test, the original scheduled fuel signals and the modified signals were compared to guarantee the consistency excluding the spiking signals. The spiking signals were carefully selected to maintain the engine speed constant. The fuel spiking effects were checked by three dynamic pressure sensors. Sensors were placed before the servo-valve, after the servo-valve, and after the compressor location, respectively. The modulations of the spiking signal duration and fuel flow rate were examined to make the- operating point approach the surge region. The real engine test was performed at the Altitude Engine Test Facility (AETF) in Korea Aerospace Research Institute (KARI). In the real engine test, fuel spiking signals with 25~50 ㎳ of spiking signal time and 17~46 % of base fuel flow rate condition were used. The dithering signal was 5~6 ㎃ at 490 Hz. The test results showed good agreement between the fuel spiking signals and the fuel line pressure signals. Also, the compressor discharge pressure signals showed fuel spiking effects and the changes of the operating point on the compressor characteristic map could be traced.

• Journal of Gastric Cancer
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• 제12권2호
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• pp.88-98
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• 2012

Purpose: Local recurrence, due to residual tumor, may occur after endoscopic resection for early gastric cancer. The aims of this study are to evaluate the predictive factors for local recurrence, and suggest an appropriate follow-up biopsy strategy. Materials and Methods: We retrospectively reviewed 396 early gastric cancers from 372 consecutive patients, who underwent endoscopic resection between January 2002 and April 2008. Cumulative recurrence rates were determined by the Kaplan-Meier method, and Cox proportional hazard analysis was used to determine the risk factors for local recurrence. Results: Local recurrence at the endoscopic resection site was found in 17 cases, among the total 396 lesions, during a median follow-up period of 48 months. The 5-year cumulative local recurrence rate was 4.8%. Multivariate analyses determined that tumor involvement at the lateral resection margin [hazard ratio: 35.9; P<0.001], uncheckable lateral resection margin [hazard ratio: 16.8; P<0.001], uncheckable or involved deep resection margin [hazard ratio: 3.76; P=0.047], and piecemeal resection [hazard ratio: 3.95; P=0.007] were associated with local recurrence. If a lesion was positive for any of these risk factors, the 5-year cumulative recurrence rate was 27.0%, while local recurrence was not found in any lesion that lacked these risk factors. Most episodes of recurrence were found during the first or second follow-up endoscopic biopsy at the ulcer scar. Conclusions: Routine follow-up biopsies at the endoscopic resection site might be unnecessary in cases where an early gastric cancer lesion was endoscopically resected en bloc with tumor-free lateral and deep margins.

• Radiation Oncology Journal
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• 제11권2호
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• pp.337-346
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• 1993

This is a retrospective cohort analysis of 58 patients who treated with postoperative radiation therapy following radical hysterectomy and bilateral pelvic adenectomy for early stage carcinoma of uterine cervix between January 1988 and December 1990 at department of radiation oncology, Keimyoung University Hospital. Sixteen percent of patients (9/58) had chemotherapy. Most patients were FIGO I b (47 patients), and FIGO I a and II a were one and ten patients, respectively. The median follow-up periods were 48.5 months. The indications for radiation therapy included pelvic lymph node metastasis, large tumor size, deep stromal invasion, lymphovascular invasion, positive surgical margin, endometrial invasion and parametrial invasion. Eighty five percent of the patients had more than one risk factor. The actuarial overall five year survival rate (5 YSR) and five year disease free survival rate (5 YDFSR) were $89.5\%,\;and\;87.8\%,$ respectively. Their overall recurrence rate was $12.1\%,$(758). Distant metastasis was the most common cause of treatment failure $(71.4\%:5/7).$ The univariate analysis of prognostic factors affecting to five year survival rate disclosed pelvic lymph node status (negative: $95.5\%,\;positive:69.2\%,$ p=0.006) and hemoglobin level $(\le11 :75\%,>11g/dl:93.3\%,p=0.05)$ as significant factor. The age status was marginally significant $(\le40:96.0\%,\;>\;40:84.3\%p=0.15).$ Multivariate analysis clarified three independent prognostic factors: pelvic lymph node metastasis (p=p.006), hemoglobin level (p=0.015) and age (p=0.035). Multivariate analysis of prognostic factor affecting to five year disease free survival rate disclosed pelvic lymph node status (p=0.0078) and status of surgical margin (p=0.008). Complications relating to radiotherapy were $10.3\%,(6/58).$ There were no severe major complication requiring surgical intervention or a long hospital stay. It is our opinion that the benefit of postoperative pelvic radiotherapy may be gained in such a high risk patient population with acceptible morbidity.

• 벤처창업연구
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• 제13권2호
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• pp.1-13
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• 2018

본 연구는 기존연구들을 분석하여 벤처기업의 성공개념을 정리하고 통합적 성공요인 모형을 도출하였다. 성공요인으로는 크게 창업자/팀 요인과 기업요인, 환경 요인 및 창업과정 요인으로 구분하여 각 요인들의 하위 구성요인들을 규명하였고, 기업성과로는 지표의 계량화 여부에 따라 정성/정량적 성과를 측정하거나 응답자의 주관적 평가 여부에 따라 주관/객관적 성과를 측정하는 것으로 통합모형을 설계하였다. 한국 벤처기업에 대한 실증분석으로는 성공 요인 중 하나인 벤처기업의 일반적 특성(업종, 규모, 소재지, 발전단계, 업력)을 주변에서 용이하게 수집할 수 있는 2차 자료를 활용하여 살펴보았다. 분석결과, 2016년 동안 기업의 평균 매출액이 가장 많은 업종은 음식료/섬유/(비)금속이며, 당기순이익이 가장 큰 업종은 컴퓨터/반도체/전자부품, 매출액 증가율이 가장 큰 업종은 정보통신/방송서비스와 소프트웨어 개발, 매출액 당기순이익률이 가장 큰 업종은 에너지/의료/정밀이었다. 종사자규모 측면에서 100인 이상 종사자의 벤처기업이 매출액과 당기순이익이 가장 많았으나, 일반적으로 종사자수와 매출액 및 당기순이익은 높은 상관관계를 보이기 때문에 이러한 결과는 큰 의미가 없으며, 오히려 매출액 증가율이나 매출액 당기순이익률이 의미가 있을 수 있는데, 특히 50~99인의 벤처기업이 이들 지표가 높았다. 소재지 측면에서 매출액이 가장 많은 지역은 서울/인천/경기였고, 당기순이익이 가장 큰 지역은 광주/전라/제주와 서울/인천/경기가 거의 비슷하였다. 매출액 증가율과 매출액 당기순이익률이 가장 큰 지역은 광주/전라/제주였다. 기업의 발전단계와 기업성과와의 관계에서는 예상대로 성숙기와 쇠퇴기의 매출액이 가장 많았다. 당기순이익도 성숙기가 가장 많았으며, 매출액 증가율은 창업기, 초기성장기, 고도성장기, 성숙기, 쇠퇴기의 순으로 전형적인 패턴을 보이고 있었다. 업력 측면에서는 매출액과 당기순이익이 가장 많은 업력은 21년 이상이었고, 창업 3년 이하가 가장 높은 매출액 증가율을 보였으며, 4~10년이 가장 높은 매출액 당기순이익률을 보였다. 연구의 논의사항에서 이들 분석결과에 대한 해석과 시사점들을 제시하였다. 본 연구는 벤처기업의 통합적 성공요인 모형을 제시하고, 한국 벤처기업의 경영성과를 분석함에 있어서 2차 자료의 활용방안을 실증적으로 보여줌으로써 여러 가지 유용한 시사점을 제시하고 있다.

• 한국유체기계학회 논문집
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• 제17권5호
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• pp.27-36
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• 2014

This paper presents a numerical investigation of the effect of the rotation speed on the performance in a transonic axial compressor with the dihedral stator. Four stator geometries with different stacking line variables were tested in the flow simulations over the whole operating range. It was found that a large shroud loss at the rotor outlet and the subsequent shroud corner separation in the stator passage occurred at low mass flow rate with the 100 % design speed. The hub dihedral stator could suppress the shroud loss region and consequently improve the stall margin. In case of the 70 % design speed condition as the mass flow rate decreased, it was seen that the high loss region was placed at the midspan of the rotor passage. The dihedral stator slightly affected the local diffusion factor, but the performance of the compressor was not changed.

• 한국유체기계학회 논문집
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• 제18권4호
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• pp.30-35
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• 2015

This study analyzed the variations in the performance and operation of a 200 kW class micro gas turbine according to performance degradation of compressor and turbine. An in-house code, developed by the present authors and presented in the first part of these series of papers, were used for the analysis. The degradation of compressor and turbine were simulated by modifications in the their performance maps: mass flow rate, pressure ratio and efficiency were decreased from the reference values. Firstly, the variations in the operating conditions (air flow rate, pressure ratio) were predicted for the full load condition. Then, the same analysis were performed for a wide partial load operating range. The change in engine's performance (power output and efficiency) due to the component degradation was predicted. In addition, the change in the compressor surge margin, which is an important indicator for safe engine operation, was evaluated.

• The Plant Pathology Journal
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• 제18권1호
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• pp.23-29
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• 2002

A total of 672 Cryphonectria parasitica was isolated from 2,536 blight lesions on chestnut twigs, which were collected from major chestnut plantations all over Korea. Isolation rates of each province ranged from 13.5% in Jeonbuk-ds to 37.4% in Gyeongnam-do, with an average rate of 25.6%. The isolates were classified into six groups according to color and shape of colony on PDA: smooth margin (S), irregular margin (I), yellow to brown (Y), white (W), and white with yellow center (C). Among these groups, IY was the most abundant with an isolation rate of 65%. On the other hand, SW, SC, IW, and SY were quite rare, with isolation rates ranging from 1.5% to 5.8%. When the 672 isolates were inoculated on the chestnut twigs,380 isolates (56.5%) caused lesions larger than the standard virulent isolate EPISS-2, while 158 isolates (23.4%) caused smaller lesions than the standard hypovirulent isolate UEP-1. However, 87.4% of the isolates belonged to the virulent group and only 12.6% belonged to the hypovirulent group based on Bavendamm test. In the provinces of Jeonnam-do, Jeonbuk-do, and Gyeongnamdo, which have high density of chestnut trees, the rates of hypovirulent-like isolates were over 20%.

• 대한원격탐사학회:학술대회논문집
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• 대한원격탐사학회 2005년도 Proceedings of ISRS 2005
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• pp.98-100
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• 2005

This paper describes link analysis on the processed data, HRIT (High Rate Information Transmission) and LRIT (Low Rate Information Transmission), for the preliminary design of interface between COMS (Communication, Ocean and Meteorological Satellite) and ground station. At the MODAC (MeteorologicaVOcean Data Application Center), the processed data are transmitted to user station via COMS with normalization and calibration by pre-processing of MI (Meteorological Imager) data. Due to consider satellite as radio relay, overall analysis containing uplink and downlink is needed. Specific link parameters can be obtained with using the outcomes of SRR (System Requirement Review) which was held on 13-14 June 2005, in Toulouse. From the relation between overall link margin and output power of HPA (High Power Amplifier) of MODAC, it is shown that even though the minimum power related with COMS receiving power range is transmitted at MODAC, the obtained link margin of HRIT could be above 3 dB at user station which antenna elevation angle is 10 degree.

• Archives of Plastic Surgery
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• 제32권4호
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• pp.454-460
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• 2005

Dematofibrosarcoma protuberans(DFSP) is a moderate-degree malignant tumor with high recurrence rate and low metastasis rate, from soft tissue. Principle of treatment is wide excision or Mohs micrographic surgery(MMS). Although wide excision has been performed with surgical margins of 2-5 cm until nowadays, there are problems of preservation of surrounding normal tissue. Therefore the authors tried to identify desirable surgical margins and operative method. From January 1999 to April 2003, 12 patients with DFSP were operated. We applied different surgical margins and operative methods according to the location of lesions. On the face, we performed MMS with surgical margin of 3-4 mm in 2 cases although there are problems of operation time and expense. But on the extremities and trunk, we performed authors' method to begin excising with surgical margins of 1 cm and excise extensively with MMS by 1 cm in 4 cases after April, 2001 although we had performed wide excision with surgical margin of 3 cm in 6 cases before. There was no recurrence or metastasis in the follow-up period. So we think that author's method is effective in surgical excision of DFSP