• Journal of Korean Ophthalmic Optics Society
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• v.19 no.4
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• pp.493-498
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• 2014

Purpose: This study utilized the Geographic Information System (GIS) which is one of the representative methods for describing visual distribution, to show the distribution of visions of middle and high school students in 16 cities or provinces in Korea. Method: The data of National Health and Nutrition Examination Survey (NHANES) were analysed from 2009 to 2011 and designed a population-based cross-sectional study. The subjects were total 1,049 students at the age of 13 to 18 and uncorrected vision was provided. Male subjects were 549 (52.3%) and female subjects were 500 (47.7%). Subjects were divided into 16 cities or provinces and average vision of regions were analysed. the differentials of vision among the regions were analysed by as a spatial analysis method. Results: The average uncorrected vision were significant difference by sex (p=0.001). However male and female student groups' average vision indicated no statistically significant difference by region in those 16 cities and provinces. In order to show the differentials of middle and high school students' vision by region with a visual distribution method, the GIS was utilized for mapping. Conclusions: The differentials of vision among regions by GIS provide a visually effective distribution map.

• Journal of the Korean Geophysical Society
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• v.6 no.1
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• pp.39-46
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• 2003

Twin stone pagodas of the ruins of Kamunsa temple at Kyongju city, Kyungsangbukdo were believed to be built in 682 during the Unified Shilla Kingdom. The 13.4-m-high granodiolite pagodas with the base of 6.78 m x 4.4 m are the largest three-story stone pagoda in Korea. The western pagoda which was re-organized in 1959 is observed to be on the process of severe weathering. Also, some stone contacts are represented by the shape of sharp chevron, which is probably caused by the uneven loading due to the structural unbalance. For the structure-safety diagnosis of the western pagoda, it is necessary to understand its site characteristics and surrounding subsurface environment. Combined geophysical survey such as seismic and resistivity methods was carried out around the western pagoda. The range of 55∼350 Ωm is shown around the pagoda from the electrical resistivity mapping by the Wenner method. The higher resistivities occur the southwestern area, while the lower (<100 Ωm) values indicating the weaker subsurface appear to be on the northeastern area. This result coincides with the measurement of a leaning angle of the pagoda. Along 6 seismic lines, about 3-m-thick uppermost section around the pagoda shows the P-wave velocity of 200∼700 m/s from the refraction survey. Based on the integrated geophysical survey, the foundation of the pagoda is estimated to be in the form of 11-m-side square down to the depth of 3 m.

• Journal of Acupuncture Research
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• v.21 no.6
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• pp.177-186
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• 2004

Introduction : Recent studies Suggested that there is a strong correlation between acupuncture stimulation and its related cortical activation. Anther study showed that either positive or negative BOLD effects could be observed depending on anatomical structure in acupuncture stimulation. In ttis study, we investigated a new acupoint $KI_6$ (照海), which was known as motor-related acupoint and obtained an evidence that the stimulation of $KI_6$ resulted in either negative or positive BOLD response to stimulation. Methods & Results : 1. Subjects and paradigms : Two separate stimulation paradigms were performed on five healthy (aged 22-23 yrs) in this study. First, the paradigm of acupuncture stimulation was that the acupuncture needle was inserted in acupoints $KI_6$, which is located in lateral side of the foot and then continuously twisted(補瀉를 除外한 捻轉法) for 70 seconds for 10 cycles of activation. During rest period (70 seconds), the needle was completed removed from acupoint. Total 60 cycles were performed and 10 images were obtained per cycle. Second, nonacupoint was randomly selected and the same paradigm was performed as acupoint stimulation. The stimulation protocol comprised 10 cycles of alternating. activation and rest (10 images per cycle). Total 60 cycles were performed and each cycle take about 1.5 sec for motor task. Subjects take an at least 15 minutes break before starting anther paradigm. 2. fMRI mapping : Multi-slice functional images were obtained on a 1.5T Magnetom Vision MRI scanner (Simens Medical, Erlangen, Germany) equipped with high performance whole-body gradients. The BOLD T2 * - weighted images were acquired with acho planar imaging sequence (TR = 1.2 sec, TE = 60 msec, and flip angle = $90_{\circ}$). The other sequence parameter are : FOV = 210 mm, matrix=$64{\times}128$ or $64{\times}64$, slice number=10 and slice thickness = 5 or 8 mm. the anatomic images were obtained with Spin-echo T1-weighted images. The resulting images were then anaiyzed with STIMULATE (CMRR, U. of Minnesota) to generate functional maps using a student T-test (p < 0.005) and cluster analysis. Both positive and negative response were evaluated. Conclusions : We have observed the activation of the motor cortex by stimulating motor-related acupoint ($KI_6$). Among five subjects, negative BOLD response was shown in four and positive response in one. All subjects showed positive response to conventional finger flexion-extension task. To understand the detailed mechanisms of correlation between acupuncture stimulation and BOLD fMRI changes and two typs of response, further study strongly required.

• Journal of the Institute of Electronics Engineers of Korea SC
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• v.49 no.1
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• pp.29-38
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• 2012

The noise generated in the process of obtaining the medical image acts as the element obstructing the image interpretation and diagnosis. To restore the true image from the image polluted from the noise, the total variation optimization algorithm was proposed by the R.O. F (L.Rudin, S Osher, E. Fatemi). This method removes the noise by fitting the balance of the regularity and fidelity. However, the blurring phenomenon of the border area generated in the process of performing the iterative operation cannot be avoided. In this paper, we propose the adaptive total variation method by mapping the control parameter to the proposed transfer function for minimizing boundary error. The proposed transfer function is determined by the noise variance and the local property of the image. The proposed method was applied to 464 tooth images. To evaluate proposed method performance, PSNR which is a indicator of signal and noise's signal power ratio was used. The experimental results show that the proposed method has better performance than other methods.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.48 no.1
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• pp.1-7
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• 2011

In this paper, we propose the digital image enhancement method including local tone reproduction and preservation of the hue. In recent studies, an integrated multi-scale retinex (IMSR) has produced great naturalness in the resulting images through enhancement of visibility in dark area in input images. However, most methods, including IMSR, work in RGB color spaces. As such, this produces hue distortion from the perspective of the human visual system, that is, hue distortion in CIELAB color space. Accordingly, this paper proposes an tone reproduction and enhancement of saturation method in a device-independent color space, CIELAB, to preserve the hue and obtain a high contrast and naturalness. First, to achieve the desired objectives, the IMSR is then applied to only the $L^*$ values in CIELAB color space, normalization, and simple mapping function, thereby preserving the balance of the color components and enhancement of visibility. Then, saturation adjustment is performed by applying the ratio of the chroma variation at the sRGB gamut boundary according to the corrected luminance. In experiments, the proposed method is shown to improve the visibility in dark shadows and bright regions in the resulting images and reduce any color distortion then preference test are performed.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.49 no.1
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• pp.73-80
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• 2012

Recent research efforts have focused on combining high dynamic range imaging with super-resolution reconstruction to enhance both the intensity range and resolution of images. The processes developed to date start with a set of multiple-exposure input images with low dynamic range (LDR) and low resolution (LR), and require several procedural steps: conversion from LDR to HDR, SR reconstruction, and tone mapping. Input images captured with irregular exposure steps have an impact on the quality of the output images from this process. In this paper, we present a simplified framework to replace the separate procedures of previous methods that is also robust to different sets of input images. The proposed method first calculates weight maps to determine the best visible parts of the input images. The weight maps are then applied directly to SR reconstruction, and the best visible parts for the dark and highlighted areas of each input image are preserved without LDR-to-HDR conversion, resulting in high dynamic range. A new luminance control factor (LCF) is used during SR reconstruction to adjust the luminance of input images captured during irregular exposure steps and ensure acceptable luminance of the resulting output images. Experimental results show that the proposed method produces SR images of HDR quality with luminance compensation.

• Sleep Medicine and Psychophysiology
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• v.17 no.2
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• pp.91-99
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• 2010

Objectives: Deficit schizophrenia (DS) constitutes a disease separate from non-deficit schizophrenia (NDS). The aim of the current study was to compare the quantitative EEG and low resolution electromagnetic tomography (LORETA) imaging between DS and NDS. Methods: This study was performed by 32 channels EEG for 42 schizophrenia patients who we categorized into DS and NDS using proxy instrument deficit syndrome (PDS). We performed the absolute power spectral analyses for delta, theta, alpha, low beta and high beta activities. We compared power spectrum between two groups using Independent t-test. Partial correlation test was performed with clinical parameters. Standardized LORETA (sLORETA) was used for comparison of cortical activity, and statistical nonparametric mapping (SnPM) was applied for the statistical analysis. Results: DS showed significantly increased delta and theta absolute power in fontal and parietal region compared with NDS (p<0.05). Power spectrum showed significant correlation with 'anergia' and 'hostility/suspiciousness' subscale of brief psychiatric rating scale (BPRS)(p<0.05). sLORETA found out the source region (anterior cingulate cortex/limbic part) that delta activity was significantly increased in DS (p=0.042). Conclusions: DS showed different cortical activity compared with NDS. Our results may suggest QEEG and LORETA could be the marker in differentiating between DS and NDS.

• The KIPS Transactions:PartA
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• v.11A no.6
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• pp.459-468
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• 2004

Sharing XML trees on mobile devices has become more and more popular. Optimistic replication of XML trees for mobile devices raises the need for reconciliation of concurrently modified data. Especially for reconciling the modified tree structures, we have to compare trees by node mapping which takes O($n^2$) time. Also, using semantic based conflict resolving policy is often discussed in the literature. In this research, we focused on an efficient reconciliation method for mobile environments, using edit scripts of XML data sent from each device. To get a simple model for mobile devices, we use the XML list data sharing model, which allows inserting/deleting subtrees only for the repetitive parts of the tree, based on the document type. Also, we use keys for repetitive part subtrees, keys are unique between nodes with a same parent. This model not only guarantees that the edit action always results a valid tree but also allows a linear time reconciliation algorithm due to key based list reconciliation. The algorithm proposed in this paper takes linear time to the length of edit scripts, if we can assume that there is no insertion key conflict. Since the previous methods take a linear time to the size of the tree, the proposed method is expected to provide a more efficient reconciliation model in the mobile environment.

• Spatial Information Research
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• v.9 no.2
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• pp.239-261
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• 2001

A large suite of official statistical data sets has been compiled for geographical units under the national directives, and it is the quantitative regional analysis procedures that could add values to them. This paper reports our attempts at prototyping a statistical GIS which is capable of serving over the Web a variety of regional analysis routines as well as value-added statistics and maps. A pilot database of some major statistical data was ingested for the city of Seoul. The baseline subset of regional analysis methods of practical usage was selected and accommodated into the business logic of the target system, which ranges from descriptive statistics, regional structure/inequality measures, spatial ANOVA, spatial (auto) correlation to regression and residual analysis. The leading-edge information technologies including the application server were adopted in the system design and implementation so that the database, analysis modules and analytic mapping components may cooperate seamlessly behind the Web front-end. The prototyped system supports tables, maps, and files of downloadable format for input and output of the analyses. One of the most salient features of out proposed system is that both the database and analysis modules are extensible via the bi-directional interface for end users; The system provides users with operators and parsers for algebraic formulae such that the stored statistical variables may be transformed and combined into the newly-derived set of variables. This functionality eventually leads to on-the-fly fabrication of user-defined regional analysis algorithms. The stored dataset may also be temporarily augmented by user-uploaded dataset; The extension of this form, in essence, results in a virtual database which awaits for users commands as usual. An initial evaluation of the proposed system confirms that the issues involving the usage and dissemination of information can be addressed with success.

• IMMUNE NETWORK
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• v.7 no.3
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• pp.149-157
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• 2007

Background: The microsatellites within human leukocyte antigen (HLA) region show considerable polymorphism and strong linkage disequilibrium (LD) with HLA alleles. These microsatellites have been used for genetic analysis including disease mapping to understand susceptibility to autoimmune and infectious diseases. Also, use of microsatellites has recently been proposed as an approach for identifying non-HLA markers within the HLA region that could function as transplantation determinants and for the selection of potential donors for transplantation. Methods: To analyse the frequency of five microsatellites in the Korean population, genotyping for polymorphisms at five microsatellites markers (BAT2, MIB, DQCAR, D6S105 and TNFd) within HLA region was performed on 143 healthy Korean controls. Results: The most frequent genotype shown in healthy Korean controls were BAT2 8 (153 bp, 42.7%), MIB 1 (326 bp, 40.6%), DQCAR 3 (188 bp, 38.5%), D6S105 7 (126 bp, 58.0%) and TNFd 3 (128 bp, 58.0%). And common two-loci haplotypes were found as MIB 1-HLA-B*62 (HF: 10.6%), MIB 6-HLA-B*44 (HF: 7.8%), DQCAR 3-HLA-DRB1*13 (HF: 8.5%), TNFd 5-HLA-B*62 (HF: 7.8%) and D6S105 7-HLA-A*02 (HF: 16.2%). Conclusion: These data might provide useful information on the microsatellites markers with HLA region in Korean population and be helpful in further defining the clinical impact of these microsatellites.