• Proceedings of the KACD Conference
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• 대한치과보존학회 2003년도 제120회 추계학술대회 제 5차 한ㆍ일 치과보존학회 공동학술대회
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• pp.591-591
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• 2003

Apical periodontitis is inflammation of the periodontium caused by infection of the pulp canal system. Moreover, a dental periradicular lesion occurs as a periradicular tissue reaction to bacterial infection and consists of periradicular inflammation with alveolar bone destruction and root resorption, a consequence of the interaction between oral flora and the existing host defenses. Many investigations dealing with the pathogenesis and history of periradicular lesions have described histologically, immunologically, biochemically the development of the periradicular lesion；but none of these studies have shown any correlation between this lesion and several factors, the whole body disease in the worldwide.(omitted)

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 한국정보통신학회 2022년도 춘계학술대회
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• pp.276-278
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• 2022

All drugs have a specific action in the body, and in many cases, drugs are combinated due to complications or new symptoms during existing drug treatment. In this case, unexpected interactions may occur within the body. Therefore, predicting drug-drug interactions is a very important task for safe drug use. In this study, we propose a deep learning-based predictive model that learns using drug information documents to predict drug interactions that may occur when using multiple drugs. The drug information document was created by combining several properties such as the drug's mechanism of action, toxicity, and target using DrugBank data. And drug information document is pair with another drug documents and used as an input to a deep learning-based predictive model, and the model outputs the interaction between the two drugs. This study can be used to predict future interactions between new drug pairs by analyzing the differences in experimental results according to changes in various conditions.

• Proceedings of the National Institute of Ecology of the Republic of Korea
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• 제2권2호
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• pp.108-113
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• 2021

Detrimental effects of inbreeding have been studied by many researchers for a long time. However, only a few studies have shown the occurrence of inbreeding depression due to evolutionary changes as a purging process. In this study, two different populations (inbreeding and outbreeding) of Drosophila melanogaster were compared to assess inbreeding effects on artificial population bottlenecks. For inbreeding conditions, a couple of D. melanogaster (one virgin and one male) were selected from an inbred population and cultured in a vial. For outbreeding conditions, a couple of D. melanogaster were selected from different populations and cultured in a vial. There were significant differences in body lengths of adults, but not in other parameters such as the total number of adults, the rate of survival, and the rate of wing mutants. The mean body length of adults of outbreeding populations was longer than that of inbreeding populations in the first generation (G1; P = 0.004), but not in the second generation (G2; P = 0.066). Although the other three parameters (total number of adults, rate of survival, and rate of wing mutants) showed differences in their mean values between inbreeding and outbreeding populations, these differences were not statistically significant. This might be due to genetic purging. This study demonstrated one additional experimental case related to inbreeding depression in artificial bottlenecked populations. Further studies are necessary to confirm the clear interaction between inbreeding depression and genetic purging using more generations and replicates (or samples) of D. melanogaster.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• 제38권6호
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• pp.547-556
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• 2010

For the safety of aircraft and accuracy of bombs, many companies have researched the new concept of adaptive kit to flying-bombs. For the long distance flying, it's normally used deployed high-aspect ratio wing because of limited volume. The probabilities of large elastic deformation and flutter are increased due to decreased stiffness of high-aspect ratio wing. In this paper, computational fluid dynamics and computational structure dynamics interaction methodology are applied for prediction of aerodynamic characteristics. FLUENT and ABAQUS are used to calculate fluid and structural dynamics. Code-bridge was made base on the compactly supported radial basis function to execute interpolation and mapping. There are some differences between rigid body and fluid-structure interaction analysis which are results of aerodynamics characteristics due to structural deformation. Small successive vibration was observed by interaction.

• The Journal of the Korea Contents Association
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• 제11권4호
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• pp.215-224
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• 2011

There have been studying many researches to detect human body and to track one with increasing interest on human and computer interaction. In this paper, we propose the algorithm that automatically extracts joints, linked points of human body, using the ratio of human body under single camera and tracks object. The proposed method gets the difference images of the grayscale images and ones of the hue images between input image and background image. Then the proposed method composes the results, splits background and foreground, and extracts objects. Also we standardize the ratio of human body using face' length and the measurement of human body and automatically extract joints of the object using the ratio and the corner points of the silhouette of object. After then, we tract the joints' movement using block-matching algorithm. The proposed method is applied to test video to be acquired through a camera and the result shows that the proposed method automatically extracts joints and effectively tracks the detected joints.

• Korean Journal of Biological Psychiatry
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• 제6권1호
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• pp.49-66
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• 1999

Polypharmacotherapy, both psychotropic and nonpsychotropic, is widespread in various situations including psychiatric hospitals and general hospitals. As the clinical practice of using more than one drug at a time increase, the clinician is faced with ever-increasing number of potential drug interactions. Although many interactions have little clinical significances, some may interfere with treatment or even be life-threatening. The objective of this review is evaluation for drug-drug interactions often encountered in psychiatric consultation. Drug interactions can be grouped into two principal subdivisions : pharmacokinetic and pharmacodynamic. These subgroups serve to focus attention on possible sites of interaction as a drug moves from the site of administration and absorption to its site of action. Pharmacokinetic processes are those that include transport to and from the receptor site and consist of absorption, distribution on body tissue, plasma protein binding, metabolism, and excretion. Pharmacodynamic interactions occur at biologically active sites. In psychiatric consultation, these two subdivisions of drug interactions between psychotropic drugs and other drugs are likely to happen. We gathered informations of the drugs used in physically ill patients who are consulted to psychiatric department in Korea University Hospital. And we reviewed the related literatures about the drug-drug interactions between psychotropic drugs and other drugs.

• Asian-Australasian Journal of Animal Sciences
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• 제17권1호
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• pp.13-17
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• 2004

The aim of this study was to investigate genetic development and genotype${\times}$environment interactions (GEI) in postweaning body weight of fattening bulls at the end of test period (WT-T) under various beef fattening environments. Data on a total of 24,247 fattening bulls obtained from the industrial farm, breeding farms and testing stations were used. Heritability estimates for WT-T in all environments were nearly similar. Significant genetic developments of sire, dam and progenies for WT-T were observed in all environments. However, many differences in annual genetic developments between the environments were significant. The genetic correlations for WT-T between industrial farm and breeding farms, industrial farm and testing stations and breeding farms and testing stations were respectively 0.004, 0.004 and 0.013. These low estimates of genetic correlations and significant differences in genetic developments among environments clearly show the existence of GEI for WT-T among various fattening environments. Results of this study indicate the need for environment-specific genetic evaluation and selection of beef bulls for commercial beef production.

• Journal of Digital Contents Society
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• 제13권2호
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• pp.255-262
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• 2012

Human motion tracking algorithm is receiving attention from many research areas, such as human computer interaction, video conference, surveillance analysis, and game or entertainment applications. Over the last decade, various tracking technologies for each application have been demonstrated and refined among them such of real time computer vision and image processing, advanced man-machine interface, and so on. In this paper, we introduce cost-effective and real-time human motion tracking algorithms based on depth image 3D point matching with a given superellipsoid body representation. The body representative model is made by using parametric volume modeling method based on superellipsoid and consists of 18 articulated joints. For more accurate estimation, we exploit initial inverse kinematic solution with classified body parts' information, and then, the initial pose is modified to more accurate pose by using 3D point matching algorithm.

• Korean Journal of Computational Design and Engineering
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• 제12권1호
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• pp.50-57
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• 2007

In recent years, many robotics researches have been focused on developing human-friendly robots, that is, humanoid biped robots. The researches of humanoid robots include various areas such as hardware development, control of biped locomotion, artificial intelligence, human interaction, etc. The present work concerns the hardware development of a mid-size humanoid robot, BONOBO, focusing on rapid development of outer body parts with integrated application if CAD/CAM/CAE/RP. Most parts are three-dimensionally designed using 3D CAD, and effectively connected with CAE analyses using both kinematic simulation and structural analysis. In order to reduce lead time and investment cost for parts developments, Rapid Prototyping (RP) and CAM are selectively utilized for manufacturing body parts. These master parts are then replicated using the vacuum casting process, from which we can obtain plastic parts repeatedly. Through this integrated approach, the first prototype of BONOBO can be successfully developed with relatively low time and investment costs.

• Journal of Computing Science and Engineering
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• 제9권1호
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• pp.29-38
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• 2015

Human action recognition has become an important research topic in computer vision area recently due to many applications in the real world, such as video surveillance, video retrieval, video analysis, and human-computer interaction. The goal of this paper is to evaluate descriptors which have recently been used in action recognition, namely Histogram of Oriented Gradient (HOG) and Histogram of Optical Flow (HOF). This paper also proposes new descriptors to represent the change of points within each part of a human body, caused by actions named as Histogram of Changing Points (HCP) and so-called Average Speed (AS) which measures the average speed of actions. The descriptors are combined to build a strong descriptor to represent human actions by modeling the information about appearance, local motion, and changes on each part of the body, as well as motion speed. The effectiveness of these new descriptors is evaluated in the experiments on KTH and Hollywood datasets.