• The Korea Journal of Herbology
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• v.28 no.4
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• pp.71-76
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• 2013

Objectives : The biological activities and compound contents of herbal medicine vary depending on manufacturing processes. In this study, we compared anti-inflammatory effects and compound contents of three kinds of multi-herbal extract HT008 produced by different manufacturing processes in order to determine chemical and biological equivalence. Methods : HT008 was produced by three different manufacturing methods: 1. Freeze dried extract of Eleutherococcus senticosus, Scutellaria baicalensis and Angelica sinensis (HT008 FD), 2. Spray dried extract of E. senticosus and S. baicalensis combined with reflux extract of A. sinensis (HT008 SD), 3. Spray dried extract of E. senticosus and S. baicalensis combined with supercritial fluid extract of A. sinensis (HT008 SF). Anti-inflammatory effects were evaluated using acetic acid induced pain model and ${\lambda}$-carageenan induced paw edema model. Compound contents were evaluated by HPLC quantitative analysis of standard compounds of HT008, eleutheroside E, baicalin, z-ligustilide. Results : HT008 FD, HT008 SD and HT008 SF significantly decreased acetic acid induced pain index and ${\lambda}$-carrageenan induced paw edema volume compared with that of control group. There was no significant difference in efficacy among the HT008 FD, HT008 SD and HT008 SF. Standard compound contents of HT008 FD, HT008 SD and HT008 SF were quantified within the range of Korean pharmacopoeia or other research. Conclusions : Three different manufacturing methods of multi-herbal extracts have been developed without noticeable difference in the efficacy or compound contents. The results might be used to establish manufacturing process and industrialization of herbal extracts.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.35 no.5
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• pp.459-465
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• 2011

Excessive heat may be generated during the semiconductor manufacturing process. Therefore, precise control of temperature is required to maintain a constant ambient temperature and wafer temperature in the chamber. Compared to an industrial chiller, a semiconductor chiller's power consumption is high because it is in continuous operation for a year. Because of this high power consumption, it is necessary to develop an energy-efficient chiller by optimizing the operation. The competitiveness of domestic products is low because of the high energy consumption. We experimentally investigated a domestic semiconductor by conducting load change, temperature rise and fall, and control precision experiments. The experimental study showed that the chiller had 2.1-3.9 kW of cooling capacity and 0.56-0.93 of EER. The control precisions were ${\pm}1^{\circ}C$ and ${\pm}0.6^{\circ}C$ when the setting temperatures were $0^{\circ}C$ and $30^{\circ}C$ respectively.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.5 no.2
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• pp.184-192
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• 1995

This study was performed to evaluate methods for determination of airbone mercury in industrial environments. Three methods, such as Hopcalite method, passive monitoring method and Jerome method were evaluated at two (2) fluorescent lamp manufacturing Plants in Korea during a period from May 24 to May 31, 1994 and the result are as follows: 1. The average were concentrations of airbone mercury were $26{\mu}g/m^3$ by Hopcalite method, $25{\mu}g/m^3$ by passive monitoring method, and $38{\mu}g/m^3$ by the Jerome method, respectively, which were below the permissible exposure limit of $50{\mu}g/m^3$ established by both the Korean Ministry of Labor and ACGIH. However, 12 out of 49 cases(24.4%) in plant A and 2 out of 31 cases(6.5%) in plant B were in excess of the standard. 2. The relationship between the results by Hopcalite method and the passive monitoring method was significant(r=0.892). 3. The variation among three results by eath of three methods were different by process. The highest variation was determined at quality control process("process b") which invoved in large variation of concentrations. 4. When short term high concentrations were produced, the Hopcalite method was more efficient then the passive method.

• Journal of the Korean Society for Precision Engineering
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• v.22 no.1
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• pp.137-142
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• 2005

Gas-Assisted Injection Molding(GAIM) is an innovative technology for producing plastic parts and has been received extensive attention in the plastic manufacturing industries. But, due to gas-polymer interacting during the gas injection phase, the process has significantly different characteristics from conventional injection molding and, therefore, the control of the process requires much technical knowledge in processing and materials. The experiment was performed about variations of gas-penetration length that is affected by filling imbalance resulting from the structure of runner. The Taguchi method was used for the design of experiment. The most effective factors for the gas-penetration length were the shot size and mold temperature. The most effective factors for the difference of the gas-penetration length were the melt temperature and shot size. This study also discussed the filling imbalance phenomenon in a unary branch runner type mold that has geometrically balanced runner.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2006.11a
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• pp.359-361
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• 2006

As circuits become increasingly complex and devices sizes shrinks, the demands placed on global planarization of higher level. Chemical Mechanical Polishing (CMP) is an indispensable manufacturing process used to achieve global planarity. In the CMP process, Diamond Disk (DD) plays an important role in the maintenance of removal rate. According to studies, the cause of removal rate decrease in the early or end stage of diamond disk lifetime comes from pad surface change. We also presented pad cutting rate (PCR) as a useful cutting ability index of DD and studied PCR trend about variable parameters that including size, hardness, shape of DD and RPM, pressure of conditioner It has been shown that PCR control ability of pressure and shape is superior to RPM and size. High pressure leads to a decrease of cell open ratio of pad surface because polyurethane of pad is destroyed by pressure. So low pressure high RPM condition is a proper removal rate sustain. By examining correlations between RPM and pressure of conditioner, it has been shown that PCR safe zoneto satisfy proper removal rate has the range 0.06mm/hr to 0.12mm/hr.

• Proceedings of the Korean Society of Machine Tool Engineers Conference
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• 2003.10a
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• pp.368-373
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• 2003

A major concern at present is the simultaneous control of transverse thickness profile and flatness in the finishing stages of hot rolling process. The mathematical modeling of hot rolling process has long been recognized to be a desirable approach to investigate rolling operating practice and the design of mill equipment to improve productivity and quality. However, many factors make the mathematical analysis of the rolling process very complex and time-consuming. In order to overcome these problems and to obtain an accurate rolling force, the predicted model of rolling force using neural networks has widely been employed. In this paper, Radial Basis Function Network(RBFN) is applied to improve the accuracy of rolling force prediction in hot rolling mill. In order to verify and analysis the performance of applied neural network, the comparison with the measured rolling force and the predicted results using two different neural networks - RBFN, MLP, has respectively been carried out. The results obtained using RBFN neural network are much more accurate those obtained the MLP.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2001.04a
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• pp.15-19
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• 2001

A dedicated reverse engineering(RE) system for rapid manufacturing of human head in a 3D bust has been developed. The first step in the process is to capture the surface details of a human head and shoulder by three scanners based upon the digital moire fringe technique. Then the multiple scans captured from different angles are aligned and merged into a single polygonal mesh, and the aligned data set is refined by smoothing, subdividing or hole filling process. Finally, the refined data set is sent to a 4-axis computer numerically control(NC) machine to manufacture a replica. In this paper, we mainly describe on the algorithms and software for aligning multiple data sets. The method is based on the recently popular Iterative Closest Point(ICP) algorithm that aligns different polygonal meshes into one common coordinate system. The ICP algorithm finds the nearest positions on one scan to a collection of points on the other scan by minimizing the collective distance between different scans. We also integrate some heuristics into the ICP to enhance the aligning process. A typical example is presented to validate the system and further research work is also discussed.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.28 no.7
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• pp.961-969
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• 2004

Most manufacturing companies are trying to develop a competitive product by increasing the quality, shortening time to market and reducing the cost of a product. Collaborators related to the development of a new product want to confirm geometric forms and dimensions during the design process, as well as to verify dimensional errors of a product during the fabrication process. Objective of this paper is the development of a collaborative design and dimension verification system on the Internet. STEP files obtained from the design process are used for the design and dimension verification. Functions of the design and dimension verification modules are constructed over the ActiveX control using the visual C/sup ++/ and OpenGL. By using mark up functions over the Internet, collaborators check geometries, interferences, dimensional errors, human factors and form errors, as well as share their design ideas and opinions with XML rapidly and remotely. The usefulness of the developed system is confirmed through case studies.

• Transactions of the Korean Society of Machine Tool Engineers
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• v.13 no.6
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• pp.29-33
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• 2004

A major concern at present is the simultaneous control of transverse thickness profile and flatness in the finishing stages of hot rolling process. The mathematical modeling of hot rolling process has long been recognized to be a desirable approach to investigate rolling operating practice and the design of mill equipment to improve productivity and quality. However, many factors make the mathematical analysis of the rolling process very complex and time-consuming. In order to overcome these problems and to obtain an accurate rolling force, the predicted model of rolling force using neural networks has widely been employed. In this paper, Radial Basis Function Network(RBFN) is applied to improve the accuracy of rolling force prediction in hot rolling mill. In order to verify and analyze the performance of applied neural network the comparison with the measured rolling force and the predicted results using two different neural networks-RBFN, MLP, has respectively been carried out. The results obtained using RBFN neural network are much more accurate those obtained the MLP.

• Journal of the Korean Society for Precision Engineering
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• v.25 no.11
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• pp.66-72
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• 2008

During the plate and foil cold rolling process, considerable values of the force of material pressure on the tool occur. These pressures cause the elastic deformation of the roll, thus changing the shape of the deformation legion. Rolled copper foils should be characterized by a good quality and light dimensional tolerances. Because of automation that is commonly implemented in flat product rolling mills, these products should meet the requirements of tightened tolerances, particularly strip thickness, and feature the greatest possible flatness. The shape of the roll gap is influenced by the elastic deformation of rolls parts of the rolling process affecter of the pressure force. However, to control roll deformation should be difficult. Because the foil thickness is very thin and the permissible deviations in the thickness of foil are small. In this paper, FE-simulation of roll deformation in thin foil cold roiling process is presented.