• BMB Reports
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• 제45권6호
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• pp.337-341
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• 2012

Different from humans, who have a continuous dentition of teeth, mice have only three molars and one incisor separated by a toothless region called the diastema in the hemi mandibular arch. Although tooth buds form in the embryonic diastema, they regress and do not develop into teeth. In this study, we evaluated the proteins that modulate the diastema formation through comparative analysis with molar-forming tissue by liquid chromatography-tandem mass spectroscopy (LC-MS/MS) proteome analysis. From the comparative and semi-quantitative proteome analysis, we identified 147 up- and 173 down-regulated proteins in the diastema compared to the molar forming proteins. Based on this proteome analysis, we selected and evaluated two candidate proteins, EMERIN and RAB7A, as diastema tissue specific markers. This study provides the first list of proteins that were detected in the mouse embryonic diastema region, which will be useful to understand the mechanisms of tooth development.

• 대한치과교정학회지
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• 제41권1호
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• pp.51-58
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• 2011

Objective: To evaluate the shear bond strength (SBS), fracture mode, wire pull out (WPO) resistance and microleakage between low-shrinking and conventional composites used as a lingual retainer adhesive. Methods: A total of 120 human mandibular incisor teeth, extracted for periodontal reasons, were collected. Sixty of them were separated into two groups. To determine the SBS, either Transbond-LR (3M-Unitek) or Silorane (3M-Espe) was applied to the lingual surface of the teeth by packing the material into standard cylindrical plastic matrices (Ultradent) to simulate the lingual retainer bonding area. To test WPO resistance, 20 samples were prepared for each composite where the wire was embedded in the composite materialand cured. Then tensile stress was applied until failure of the composite occurred. The remaining 60 teeth were divided into two groups and multi-stranded 0.0215-inch diameter wire was bonded with the same composites. Microleakage was evaluated by the dye penetration method. Statistical analyses were performed by Wilcoxon, Pearson chi-square, and Mann-Whitney-U tests at p < 0.05 level. Results: The SBS and WPO results were not statistically significant between the two groups. Significant differences were found between the groups in terms of fracture mode (p < 0.001). Greater percentages of the fractures showed mix type failure (85%) for Silorane and adhesive (60%) for Transbond-LR. Microleakage values were lower in low-shrinking composite than the control and this difference was found to be statistically significant (p < 0.001). Conclusions: Low-shrinking composite produced sufficient SBS, WPO and microleakage values on the etched enamel surfaces, when used as a lingual retainer composite.

• 대한치과교정학회지
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• 제45권4호
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• pp.190-197
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• 2015

Objective: The aim of the study was to analyze the prevalence and distribution of ectopic eruption of the permanent maxillary first molar (EEM) in individuals scheduled for orthodontic treatment and to investigate the association of EEM with dental characteristics, maxillary skeletal features, crowding, and other dental anomalies. Methods: A total of 1,317 individuals were included and randomly divided into two groups. The first 265 subjects were included as controls, while the remaining 1,052 subjects included the sample from which the final experimental EEM group was derived. The mesiodistal (M-D) crown width of the deciduous maxillary second molar and permanent maxillary first molar, maxillary arch length (A-PML), maxillomandibular transverse skeletal relationships (anterior and posterior transverse interarch discrepancies, ATID and PTID), maxillary and mandibular tooth crowding, and the presence of dental anomalies were recorded for each subject, and the statistical significance of differences in these parameters between the EEM and control groups was determined using independent sample t -tests. Chi-square tests were used to compare the prevalence of other dental anomalies between the two groups. Results: The prevalence of maxillary EEM was 2.5%. The M-D crown widths, ATID and PTID, and tooth crowding were significantly greater, while A-PML was significantly smaller, in the EEM group than in the control group. Only two subjects showed an association between EEM and maxillary lateral incisor anomalies, which included agenesis in one and microdontia in the other. Conclusions: EEM may be a risk factor for maxillary arch constriction and severe tooth crowding.

• 대한치과보철학회지
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• 제44권5호
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• pp.537-548
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• 2006

Statement of problem : The use of mouthguard is important as the leisure life is popular today. Purpose: The purpose of this study is to investigate the effect of a mouthguard on stress distribution in teeth, maxilla and mandible for maxilla impact. Material and methods: The 3-dimensional finite element model was based on a CT scan film of an average korean adult when the subject is using a customized mouthguard which was made with the Signature Mouthguard system of Dreve. The load was applied to the upper central incisor cervical area parellel impact force for 0.1sec(L1). The Von-mises stress analysis with a mouthguard and without a mouthguard was compared. Results: The results of this study were as follows: 1. Without the mouthguard, stress was concentrated on teeth and alveolar bone in all load conditions. 2. With the mouthguard. maximum stress value was decreased and stress was dispersed in all load conditions. 3. Stress extinction with the mouthguard was faster than without the mouthguard in all load conditions. Conclusion: We acknowledged that the mouthguard has a stress buffer effect as the maximum stress value was decreased and stress was dispersed when impact force was applied.

• 대한소아치과학회지
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• 제35권3호
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• pp.523-531
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• 2008

상악골과 치조골 전돌을 가진 II급 부정교합 증례 중 상악 치아 발치의 적응증이 아닌 경우와 하악 구치의 전방 이동을 허용할 수 없는 경우 상악 대구치의 원심이동 기법을 사용하게 된다. Pendulum 장치는 환자의 협조도 없이 상악 대구치를 원심 이동시킬 수 있는 효과적인 장치로 소구치를 안정화시키며, 구개측 고정원을 이용할 수 있다. 하지만 구치부 정출로 하안면 고경이 증가할 수 있고, 전치부 전방 이동이 동반되며, 추벽부 조직에 손상을 줄 수 있으므로 장치의 사용과 환자 선택에 신중을 기해야 한다. 이에 pendulum 장치를 사용하여 상악 대구치를 원심 이동시킴으로써 공간 문제를 해결하고, 대구치 관계를 개선한 증례들을 보고하는 바이다.

• 음성과학
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• 제8권3호
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• pp.161-172
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• 2001

Ankyloglossia (tongue-tie) limits movement of the tongue connected with feeding and has adverse impacts on both dental health and speech. For the patients with ankyloglossia, surgical intervention is recommended as primary treatment. This study suggests the efficient tool in determining indicatory factors for frenulotomy by quantifying Maximum Lingual Length-Protrusion (MLL-P) with boley gauge, and as a preliminary study, to show the measurement results with normal children using the tool. The subjects were 61 normal children, and the distance (MLL-P) between mandibular central incisor and tongue tip during tongue protrusion was measured with a boley gauge (Digimatic $Caliper^{(R)}$). The results of this study can be summarized as follows: (1) The mean value of MLL-P (N=61 normal children) was 21.44 mm, (2) The mean value of MLL-P was 20.69 mm in males (N=33) and 21.91 mm in females (N=28). There was no statistically significant difference between males and females, (3) The mean value of MLL-P was 19.34 mm, 21.19 mm, 22.33 mm, 22.61 mm for measurement of 3-, 4-, 5- and 6-year-old children, respectively, and (4) The mean value of MLL-P showed statistically significant difference between 3- and 5-year-old children, between 3- and 6-year old children.

• 대한소아치과학회지
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• 제40권2호
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• pp.127-132
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• 2013

외상에 의한 미성숙 영구치의 손상은 유치열에서 영구치열로 이환되는 8~10세경에 가장 빈발하며 전체 외상 환자의 높은 빈도를 차지한다. 외상에 대한 결과는 치아의 파절, 전위, 함입, 정출, 탈구 등의 경조직 손상 뿐 아니라 치수, 치주인대, Hertwig 상피 근초, 치조골, 치은 및 구강점막 등의 치아 인접조직의 손상도 포함한다. 일반적으로 Hertwig 상피 근초는 외상성 손상에 취약하지만, 때때로 감염이나 외상에 의한 손상을 견디고 생활력을 유지하여 치근성장에 대한 정상적인 기능을 수행하는 것이 보고된 바 있다. 본 증례에서는 외상에 의해 완전 탈구된 미성숙 영구치를 가진 두 명의 환자에 대해 보고하고자 한다. 첫 번째 환자의 경우 탈구된 상악 중절치를 재식하였고 두 번째 환자의 경우 탈구된 하악 중절치를 재식하지 않았다. 하지만 두 환자 모두에서 탈구된 치아의 치조와 부위에 분리된 치근의 계속적인 성장을 보이는 바 이를 보고하고자 하며, 나아가 계속적인 치근형성에 있어서 미성숙 치수 조직과 Hertwig 상피 근초의 생활력 보존이 결정적임을 알리고자 한다.

• 대한치과교정학회지
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• 제51권5호
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• pp.321-328
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• 2021

Objective: To examine the accuracy of computer-aided intraoperative navigation (Ci-Navi) in bimaxillary orthognathic surgery by comparing preoperative planning and postoperative outcome. Methods: The study comprised 45 patients with congenital dentomaxillofacial deformities who were scheduled to undergo bimaxillary orthognathic surgery. Virtual bimaxillary orthognathic surgery was simulated using Mimics software. Intraoperatively, a Le Fort I osteotomy of the maxilla was performed using osteotomy guide plates. After the Le Fort I osteotomy and bilateral sagittal split ramus osteotomy of the mandible, the mobilized maxilla and the distal mandibular segment were fixed using an occlusal splint, forming the maxillomandibular complex (MMC). Real-time Ci-Navi was used to lead the MMC in the designated direction. Osteoplasty of the inferior border of the mandible was performed using Ci-Navi when facial symmetry and skeletal harmony were of concern. Linear and angular distinctions between preoperative planning and postoperative outcomes were calculated. Results: The mean linear difference was 0.79 mm (maxilla: 0.62 mm, mandible: 0.88 mm) and the overall mean angular difference was 1.20°. The observed difference in the upper incisor point to the Frankfort horizontal plane, midfacial sagittal plane, and coronal plane was < 1 mm in 40 cases. Conclusions: This study demonstrates the role of Ci-Navi in the accurate positioning of bone segments during bimaxillary orthognathic surgery. Ci-Navi was found to be a reliable method for the accurate transfer of the surgical plan during an operation.

• Journal of Periodontal and Implant Science
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• 제48권6호
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• pp.395-404
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• 2018

Purpose: The purpose of this study was to propose a technique for periodontal biotype modification through thickening of the entire facial aspect using a volume-stable collagen matrix and autogenous subepithelial connective tissue graft (CTG) for the treatment of gingival recession. Methods: Four systemically healthy patients showing Miller class I or class II gingival recession in the mandibular incisor area were included in this study. Full-mouth scaling and root planing procedures were performed at least 4 weeks prior to periodontal plastic surgery. A split-thickness flap with a horizontal intrasulcular incision and 2 vertical incisions was used in cases 1-3, and the modified tunnel technique was used in case 4 for coronal advancement of the mucogingival complex. After the exposed root surfaces were debrided thoroughly, double-layered volume-stable collagen matrix was placed on the apical part of the recession and a subepithelial CTG harvested from the palatal area was placed on the coronal part. The amount of root coverage at 3 months postoperatively was evaluated in cases 1-3, and facio-lingual volumetric changes were analyzed in cases 1 and 2. Results: Healing was uneventful in all 4 cases and complete root coverage was shown in cases 1-3. In case 4, reduction of gingival recession was observed at 3 months after surgery. In cases 1 and 2, a comparison of stereolithographic files from the preoperative and postoperative time points demonstrated that the entire facio-lingual volume had increased. Conclusions: The surgical technique suggested herein, using a volume-stable collagen matrix and autogenous subepithelial CTG, may be an effective method for periodontal biotype modification through thickening of the entire facial aspect for the treatment of gingival recession.

• 대한치과교정학회지
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• 제29권2호
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• pp.219-237
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• 1999

영구치의 치근흡수는 대개 특별한 상황, 즉 외상, 감염, 교정적 치아이동, 또는 전신질환의 경우에만 일어난다고 생각되어 왔지만, 정상적인 상황에서도 영구치의 치근흡수를 나타낼 수 있음이 보고된 이래로 치근흡수의 원인을 밝히려는 많은 연구가 있었다. 특히, 교정치료와 연관된 치근흡수의 빈도 및 심각도에 관한 많은 연구들이 있음에도 불구하고 실제로 교정치료를 위해 내원한 영구치열기의 부정교합 환자에서 교정치료전 치근흡수에 대한 연구는 없었다. 이에 본 연구는 교정치료를 위해 내원한 부정교합 환자 중에서 제 3대구치를 제외한 모든 영구치의 치근 형성이 완료된 사람을 대상으로 전치부는 평행촬영법으로 촬영한 구강내 치근단 방사선 사진을, 구치부는 파노라마 방사선 사진을 이용하여 교정치료전 치근흡수의 빈도 및 심각도를 분석하였다. 본 연구에서는 개개 치아에서 치근흡수의 빈도 및 심각도와 나이, 성별, Angle씨 분류법에 따른 부정교합 분류, 수평피개 및 수직피개, 상하악 전치부 치축각도 등의 분류에 따른 치근흡수의 빈도 및 심각도,그리고 개개 치아에서 나타나는 부정교합의 특징 및 뚜렷한 교합마모면과 치근흡수의 빈도에 대해서 분석해 보아 다음과 같은 결론을 얻었다. 1. 본 연구에서 조사된 모든 사람에서 하나 이상의 치아에서 치근흡수를 나타내었고, 총 22,099개의 치아 중에서 7,920 개의 치아, 즉 $35.84\%$에서, 또 남성보다는 여성에서 빈도가 높았다(p<0.01). 2. 개개 치아에서의 치근흡수 감수성은 전체적인 이환치아에 대해서는 하악 전치, 상악 전치 순으로 감수성이 높았지만, 뚜렷한 치근흡수에 대해서는 상악 중절치, 상악 제 1 소구치, 상악 측절치 순으로 감수성이 높았다. 3. 상하악 전치의 치축 각도에 대해서는 상악 전치 치축 각도가 클수록 상악4전치의 치근흡수에 미치는 영향이 컸고, 하악 전치 치축 각도가 클수록 하악 4 전치의 치근흡수에 미치는 영향이 컸다. 4. 수평피개보다는 수직피개가 치근흡수에 미치는 영향이 컸으며 개방교합의 경향이 커질수록 치근흡수의 빈도가 높았다. 5. 개개 치아에서 나타나는 부정교합의 특징에 대해서는 반대교합과 개방교합을 함께 나타내는 치아에서 치근흡수의 빈도가 가장 높았다.