• Title/Summary/Keyword: Malignant musculoskeletal tumor

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Surgical Treatment of Malignant Tumors in Shoulder Girdle (견갑관절 주위 악성종양의 치료경험)

  • Song, Seok-Whan;Chang, Ju-Hai;Kang, Yong-Koo;Kim, Jung-Man;Kim, Hyoung-Min;Rhee, Seung-Koo;Woo, Young-Kyun;Bahk, Won-Jong;Moon, Myung-Sang;Kim, Yang-Soo
    • The Journal of the Korean bone and joint tumor society
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    • v.1 no.1
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    • pp.68-76
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    • 1995
  • To evaluate the clinical result of surgical treatment of malignant tumors in shoulder girdle, nine patients who were treated in Department of Orthopedics, Catholic University Medical College between January 1991 and December 1993, were evaluated. There were 5 men, 4 women. The mean age at operation was 47 years(range from 22 to 64 years). Of 9 patiens, 2 were soft tissue tumors(1 MFH, 1 dermatofibrosarcoma protuberance); one was treated with forequarter amputation, and the other with wide excision, Seven were bone tumor(2 chondrosarcoma, 1 osteosarcoma, 1 MFH, 1 plasmacytoma, 1 thyroid carcinoma metastasis, 1 malignant schwannoma); one patient was treated with segmental excision of proximal humerus, 4 with Malawer type I-A resection and arthroplasty or arthrodesis, 1 with Malawer type V-B resection and arthrodesis. Five patients received adjuvant chemotherapy, with or without local radiation therapy, and one patient received radiation therapy alone. All patients have survived now, but I had local recurrence. Functional results of arthrodesis and arthroplasty were similar.

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Malignant Tumor of the Pelvic Bone (골반골의 악성종양)

  • Shin, Kyoo-Ho;Hahn, Soo-Bong;Kung, Yun-Pei
    • The Journal of the Korean bone and joint tumor society
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    • v.1 no.2
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    • pp.181-188
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    • 1995
  • Malignant tumor of the pelvic bone has nonspecific symptom and it is not easily detected by physical examination or by radiologic study in early stage, because of its anatomical characteristics. Associated with their variety of disease entity, the treatment of malignant pelvic bone tumor is a problematic point. We have analysed 36 cases of malignant pelvic bone tumors diagnosed at the Severance hospital from 1968 to 1993 to provide a reference for diagnosis and treatment of the malignant pelvic bone tumors. We found that the chondrosarcoma(27.8%) and the osteogenic sarcoma(27.8%) were the most common type of pelvic bone malignancy, and then, in the order of incidence, there were Ewing's sarcoma(16.7%), malignant fibrous histiocytoma(11.1%). There were differences of the age distribution among each diseases and the average age was Ewing's sarcoma 20.5, osteogenic sarcoma 27.2, chondrosarcoma 40.0, malignant fibrous histiocytoma 64.8, respectively. Three of the 5 patients with low grade tumors survived(60%), whereas 3 of the 17 patients with high grade tumors survived(18%). The survival rate of the low grade malignant group was 60%, the high grade was 18%.

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Synchronous Double Primary Malignant Neoplasm Consisted of Myxofibrosarcoma of the Forearm and Adenocarcinoma of Rectum (전완부의 점액섬유육종과 직장의 선암이 동반된 동시성 다발성 원발성 종양)

  • Chung, Kee-Yun;Chun, Young-Soo;Han, Chung-Soo;Choi, Il-Hoen
    • The Journal of the Korean bone and joint tumor society
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    • v.14 no.2
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    • pp.146-151
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    • 2008
  • Multiple primary malignant neoplasm of the combination of the musculoskeletal system and the gastrointestinal system were very rare. A case of synchronous double primary malignant neoplasm consisted of myxofibrosarcoma of forearm and adenocarcinoma of rectum in a 52 year-old man was found. The patient had pain and swelling on forearm for 1 year. Histologically, the lesion on forearm showed myxofibrosarcoma. In systemic evaluation, the adenocarcinoma of rectum was found by the sigmoidoscopy, and metastasis on lung and intracardiac mass were found by the CT scan. We performed surgical excision and pre and postoperative chemotherapy after pathologic confirmation. He died of pulmonary thromboembolism after postoperative 2 months. We report this case of exceedingly rare combination of the musculoskeletal system and the gastrointestinal system.

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Diagnosis of Primary Malignant Lesion Using $^{18}F$ FDG PET/CT in Metastatic Bone Tumor (전이성 골종양에서 $^{18}F$ FDG PET/CT를 이용한 원발성 악성 질환의 진단)

  • Yoon, Hoi-Soo
    • The Journal of the Korean bone and joint tumor society
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    • v.14 no.1
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    • pp.44-50
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    • 2008
  • Purpose: To evaluate usefulness in diagnosing primary malignant lesion of metastatic bone tumor using $^{18}F$ FDG PET/CT. Material & Methods: Retrospective analysis was executed on 5,452 patients who were taken with $^{18}F$ FDG PET/CT between December 2003 and December 2007. 180 patients who had not any history of malignancy and complained musculoskeletal pain and had ill-defined osteolytic lesion in plain X-ray, were included. 96 male and 84 female were enrolled and mean age was 59.1 year old (22~90). We analyzed diagnostic accuracy, age and sex distribution of primary malignant lesion, location of metastatic lesion. Results: We could confirmed primary malignant lesion in 152 cases (84.4%). Most common malignant primary lesion was lung (28.3%), breast (18.9%) and gastrointestinal system (16.7%) and spine was the most common metastatic location of primary malignant lesion. Conclusion: $^{18}F$ FDG PET/CT is a effective molecular imaging detecting primary malignant lesion in patients having metastatic bone lesion without history of malignancy.

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Clinical Applications of $^{18}F$-FDG PET/CT in Malignant Bone and Soft Tissue Tumors (악성 골 및 연부조직 종양에서 $^{18}F$-FDG PET/CT의 임상적 적용)

  • Shin, Duk-Seop
    • The Journal of the Korean bone and joint tumor society
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    • v.14 no.2
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    • pp.86-94
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    • 2008
  • $^{18}F$-FDG PET/CT has led to advancement in diagnostic imaging, providing correlation of both physiology and anatomic information, and to new and innovative ways to utilize PET/CT imaging for the evaluation of musculoskeletal tumors. Recently, the most widely utilized musculoskeletal application of PET/CT imaging is for the detection and characterization of bone metastases, staging and restaging of primary malignant bone tumors and soft tissue sarcomas. And it is also useful in evaluating response to therapy for malignant musculoskeletal tumors and in detecting local recurrences or distant metastases during follow up. The future likely holds even more unique and potentially quite useful applications of PET/CT imaging for primary bone and soft tissue tumors. This article will review the useful applications of $^{18}F$-FDG PET/CT imaging for evaluating musculoskeletal tumors.

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Rapidly Destructive Coxarthrosis Mimicking a Malignant Bone Tumor - A Case Report - (악성 골 종양으로 오인된 급속 파괴형 고관절증 - 증례 보고 -)

  • Lee, Hyung-Seok;Kim, Jung-Ryul
    • The Journal of the Korean bone and joint tumor society
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    • v.14 no.2
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    • pp.203-207
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    • 2008
  • Rapid destructive hip osteoarthritis is a rare subset of osteoarthritis with rapid destruction of the hip joint within months of the onset of symptoms. The entity simulates rheumatoid arthritis, septic arthritis, neuropathy or malignant bone tumor. We report a case of rapidly destructive coxarthrosis of the right hip joint initially misdiagnosed as a malignant bone tumor at outside hospital in a 80-year-old woman.

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Malignant Tumor of the Hand (수부에 발생한 악성 종양)

  • Park, Hong-Jun;Shin, Kyoo-Ho;Bae, Im-Don;Hahn, Soo-Bong;Kang, Eung-Shick
    • The Journal of the Korean bone and joint tumor society
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    • v.5 no.4
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    • pp.201-207
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    • 1999
  • Malignant tumors of the hand are very rare. Between 1989 and 1998, 17 patients with malignant tumors of the hand were evaluated for clinical features, prevalence, treatment and results. The mean age was 45 years and median duration of follow-up was 38 months. A painless mass was the most common symptom and the most common lesion was the digit. Fifteen cases of soft tissue and 2 cases of bone tumor were diagnosed. On pathology, soft tissue tumors were comprised of 8 cases of malignant melanoma, 2 cases of angiosarcoma and 1 case each of malignant fibrous histiocytoma, malignant peripheral nerve sheath tumor, extraskeletal chondrosarcoma, and squamous cell carcinoma. Bone tumors were metastatic tumors and each originated from the rectal cancer or lung cancer. Lymph node involvements were noted in 4 cases of malignant melanoma and 1 case of squamous cell carcinoma. Six cases of metacarpo-phalangeal joint disarticulation and 4 cases of phalanx amputation were performed. Wide excision, ray amputation and below-elbow amputation were also performed. Three cases expired due to metastasis and progression of the original lesion. Among the surviving 14 cases, a malignant melanoma had metastasis on the axillary lymph node and 13 cases showed no local recurrence or metastasis during the follow-up.

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Malignant Proliferating Trichilemmal Tumor - A Case Report - (악성 증식성 모낭 종양 - 증례 보고 -)

  • Hong, Ki-Do;Kim, Jae-Young;Ha, Sung-Sik;Sim, Jae-Chun;Cho, Hye-Jae;Choi, Yoon-Ho
    • The Journal of the Korean bone and joint tumor society
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    • v.15 no.1
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    • pp.65-68
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    • 2009
  • Proliferating trichilemmal tumor(PTT) is a rare neoplasm derived from the outer root sheath of the hair follicle. Malignant transformation is rare, but abrupt enlargement of size, infiltrative growth, and non-scalp location are suggestive of malignant PTT. Histopathologic characteristics of malignant PTT are nuclear atypia, pleomorphism, and mitotic figures. Recurrence and metastasis have been documented in malignant PTT. Wide resection of the tumor with the normal tissue and accurate follow-up is the treatment of choice of the both malignant and benign PTT. We report a 51-year-old man with the mass on right 5th finger distal phalanx for 7 years. The tumor was excised with middle phalangiectomy, and based on the histopathologic findings of the tumor, this case was diagnosed as mailignant PTT. We cannot detect recurrence and metastasis because the patient was lost to follow-up.

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Malignant Extrarenal Rhabdoid Tumor in Soft Tissue - A Case Report - (연부 조직에 발생한 악성 횡문근양 종양 - 증례 보고 -)

  • Lee, Sang-Hoon;Kim, Han-Soo;Oh, Joo-Han;Suh, Sung-Wook;Lee, Han-Koo
    • The Journal of the Korean bone and joint tumor society
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    • v.6 no.4
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    • pp.173-177
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    • 2000
  • Malignant rhabdoid tumor is a highly aggressive tumor of children, that often arises in the kidney. Some rhabdoid tumors have been reported in various extra-renal location including the central nervous system, liver, skin, and soft tissues. In case of arising in soft tissues, it may be misdiagnosed as rhabdomyosarcoma. It is important to distinguish malignant rabdoid tumor from rhadomyosarcoma, because malignant rhabdoid tumor has more aggressive behavior and poorer survival rate. And this differential diagnosis can be performed by several immunohistochemistry. Here we report a case of malignant rhabdoid tumor that arose in lower abdominal wall with related articles.

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Malignant Transformation to Osteosarcoma from GCT (골육종으로 악성 전환된 거대 세포종 - 증례 보고 -)

  • Cho, Wan-Hyung;Lee, Seung-Jun;Cho, Sang-Hyeon;Lee, Soo-Yong
    • The Journal of the Korean bone and joint tumor society
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    • v.13 no.2
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    • pp.167-172
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    • 2007
  • Malignant transformation of giant cell tumor (GCT) is known to be rare. Most of malignant transformation is reported to occur after radiation and malignant transformation without prior radiation is extremly rare. Both radiographic and pathologic findings are confusing to make a correct diagnosis. Due to the poor prognosis, early aggressive treatment is mandatory. We report this rare case together with the review of the literature.

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