• 제목/요약/키워드: Male Reproduction

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Polyunsaturated Fatty Acids in Male Ruminant Reproduction - A Review

  • Tran, Len Van;Malla, Bilal Ahmad;Kumar, Sachin;Tyagi, Amrish Kumar
    • Asian-Australasian Journal of Animal Sciences
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    • 제30권5호
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    • pp.622-637
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    • 2017
  • Fatty acids such as n-3 and n-6 polyunsaturated fatty acids (PUFA) are critical nutrients, used to improve male reproductive performance through modification of fatty acid profile and maintenance of sperm membrane integrity, especially under cold shock or cryopreservation condition. Also, PUFA provide the precursors for prostaglandin synthesis and can modulate the expression patterns of many key enzymes involved in both prostaglandin and steroid metabolism. Many studies carried out on diets supplemented with PUFA have demonstrated their capability to sustain sperm motility, viability and fertility during chilling and freezing as well as improving testis development and spermatogenesis in a variety of livestock species. In addition to the type and quantity of dietary fatty acids, ways of addition of PUFA to diet or semen extender is very crucial as it has different effects on semen quality in male ruminants. Limitation of PUFA added to ruminant ration is due to biohydrogenation by rumen microorganisms, which causes conversion of unsaturated fatty acids to saturated fatty acids, leading to loss of PUFA quantity. Thus, many strategies for protecting PUFA from biohydrogenation in rumen have been developed over the years. This paper reviews four aspects of PUFA in light of previous research including rumen metabolism, biological roles, influence on reproduction, and strategies to use in male ruminants.

An infertile patient with Y chromosome b1/b3 deletion presenting with congenital bilateral absence of the vas deferens with normal spermatogenesis

  • Kuroda, Shinnosuke;Usui, Kimitsugu;Mori, Kohei;Yasuda, Kengo;Asai, Takuo;Sanjo, Hiroyuki;Yakanaka, Hiroyuki;Takeshima, Teppei;Kawahara, Takashi;Hamanoue, Haruka;Kato, Yoshitake;Miyoshi, Yasuhide;Uemura, Hiroji;Iwasaki, Akira;Yumura, Yasushi
    • Clinical and Experimental Reproductive Medicine
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    • 제45권1호
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    • pp.48-51
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    • 2018
  • We report the case of a 46-year-old Chinese male patient who visited our clinic complaining of infertility. Semen analysis revealed azoospermia, and azoospermia factor c region partial deletion (b1/b3) was detected using Y chromosome microdeletion analysis. Testicular sperm extraction was performed after genetic counseling. The bilateral ductus deferens and a portion of the epididymis were absent, whereas the remaining epididymis was expanded. Motile intratesticular spermatozoa were successfully extracted from the seminiferous tubule. On histopathology, nearly complete spermatogenesis was confirmed in almost every seminiferous tubule. To our knowledge, this is the first case report of b1/b3 deletion with a congenital bilateral absence of the vas deferens and almost normal spermatogenesis.

Neuroendocrine System in Seasonal Breeder: Focusing on the Reproductive Activity of Male Golden Hamster

  • Choi, Don-Chan;Lee, Seung-Hoon
    • 한국발생생물학회지:발생과생식
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    • 제16권1호
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    • pp.1-8
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    • 2012
  • The reproduction of animals is a way to maintain their species and demands a large amount of energy. The golden hamsters are seasonal breeders whose reproductive activities are regulated by photoperiod (length of day time in a day). The photic information received is transported to the pineal gland via many steps. Melatonin produced by the pineal gland affects the reproductive neuroendocrine system to manage reproductive activities. The major regulator neurons, secreting gonadotropin-releasing hormone, integrate all kinds of information to govern the reproductive frame hypothalamuspituitary-gonad axis. The elements impinging on the neurons are recently outspread. Thus the present review is to briefly survey the elements discovered newly and subjected to the active research realm and their correlations, focusing on the regulation of reproduction in mainly male golden hamsters as a representative animal.

The reactive oxygen species-total antioxidant capacity score is a new measure of oxidative stress to predict male infertility

  • Sharma, Rakesh K.;Pasqualotto, Fabio F.;Nelson, David R.;Thomas Jr, Anthony J.;Agarwal, Ashok
    • 대한생식의학회:학술대회논문집
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    • 대한불임학회 2000년도 제39차 춘계 학술대회
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    • pp.29-35
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    • 2000
  • The imbalance between reactive oxygen species (ROS) production and total antioxidant capacity (TAC) in seminal fluid indicates oxidative stress and is correlated with male infertility. A composite ROS-TAC score may be more strongly correlated with infertility than ROS or TAC alone. We measured ROS, TAC, and ROS-TAC scores in semen from 127 patients and 24 healthy controls. Of the patients, 56 had varicocele, eight had varicocele with prostatitis, 35 had vasectomy reversals, and 28 had Idiopathic infertility. ROS levels were higher among infertile men, especially those with varicocele with prostatitis (mean ${\pm}$ SE, 3.25 ${\pm}$ 0.89) and vasectomy reversals (2.65 ${\pm}$ 1.01). All infertility groups had significantly lower ROS-TAC scores than control. ROS-TAC score identified 80% of patients and was significantly better than ROS at identifying varicocele and idiopathic infertility. The 13 patients whose partners later achieved pregnancies had a mean ROS-TAC score of 47.7 ${\pm}$ 13.2, similar to controls but significantly higher than the 39 patients who remained infertile (35.8 ${\pm}$ 15.0; P < 0.01). ROS-TAC score is a novel measure of oxidative stress and Is superior to ROS or TAC alone in discriminating between fertile and infertile men. Infertile men with male factor or idiopathic diagnoses had significantly lower ROS-TAC scores than controls, and men with male factor diagnoses that eventually were able to initiate a successful pregnancy had significantly higher ROS-TAC scores than those who failed.

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설치류 수컷 생식력에 미치는 에스트로겐의 효과 (Estrogen Function in Male Rodents Fertility)

  • 김지향;김진규;윤용달
    • 한국발생생물학회지:발생과생식
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    • 제9권2호
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    • pp.85-93
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    • 2005
  • 스테로이드 호르몬인 에스트로겐은 여러 조직의 발생 및 분화에 영향을 주는 것으로 알려져 있다. 최근 에스트로겐의 영향을 평가하는데 있어 전통적인 여성 호르몬이라는 인식을 탈피하여 수컷 생식계상의 역할에 관한 연구가 활발하게 이루어지고 있다. 특히 내분비계 교란물질에 관한 다양한 연구 결과가 보고되면서, 수컷에서의 에스트로겐 역할에 대한 관심이 증대되고 있는 실정이다. 따라서 에스트로겐의 정확한 역할을 파악하기 위해서 발생 단계에 따른 에스트로겐 수용체의 수컷 생식기관 내 분포를 정리해 보고, 내분비계 교란물질의 노출에 따른 수컷 생식계의 발생 및 분화 이상과 정자형성과정의 장애 등을 알아보고자 하였다. 끝으로 외인성 화학물의 에스트로겐성을 평가하기 위한 지표인자들을 정리하여, 남성 생식기관의 발생, 분화, 기능에 관련된 에스트로겐의 역할에 대한 실제적인 정보를 얻을 수 있을 것으로 사료된다.

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Sexual Reproduction of Anthoplexaura dimorpha(Gorgonacea: Octocorallia) from Munseom, Jejudo Islands, Korea

  • Seo, Su-Yeon;Hwang, Sung-Jin;Song, Jun-Im
    • Animal cells and systems
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    • 제12권4호
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    • pp.231-240
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    • 2008
  • The gorgonian coral Anthoplexaura dimorpha Kukenthal, 1908(Gorgonacea: Octocorallia) is abundant in Jejudo Islands, Korea. To investigate the sexual reproduction of this species, we surveyed the morphology and cycle of gametogenesis. 5-6cm long fragments from 3-7 randomly chosen colonies were collected monthly at a depth of 12-24m in the water surrounding Munseom from August 2003 to August 2005. This species was gonochoric with sex ratio of 1.86:1(female to male), and had one annual reproductive cycle affected by elevation of seawater temperature. Oogenesis was longer than spermatogenesis as 12 months in female and 6 months in male. The planulae were not observed from the field survey and histological sections, which suggested broadcast spawning for the reproductive mode in this species. The possible spawning events may occur after the seawater temperature attain to the annual peak in September.

Assessment on combined repeated dose and reproduction/developmental toxicity of benzoyl peroxide

  • Sanghwan Song;Kim, Su-Hyon;Heekyung Bae;Lee, Moon-Soon;Park, Kwangsik
    • 한국독성학회:학술대회논문집
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    • 한국독성학회 2002년도 Molecular and Cellular Response to Toxic Substances
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    • pp.171-171
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    • 2002
  • This study was carried out by an Korean GLP laboratory to assess the combined repeated dose, reproduction and developmental toxicity of benzoyl peroxide for OECD SIDS(Screening Information Data Set) program. Male and female Sprague Dawley rats were exposed to benzoyl peroxide at levels of 0, 250, 500 and 1,000 mg/kg/day for 29 days for male and for 41-51 days for female.(omitted)

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돼지의 산자성비에 대한 조사 (Investigations on Sex Ratio of offspring in Swine)

  • 상병찬;박태진;박무균;한성욱
    • 한국가축번식학회지
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    • 제8권2호
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    • pp.92-96
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    • 1984
  • This study was carried out ot examine the sex ratios of offspring in swine. The sex ratios were obtained on the basis of the data from 15,892 pigs produced by 1,728 litters of Landrace, Large Yorkshire, Hampshire and Duroc breeds at National Animal Breeding Institute from 1975 to 1980. The results obtained are summarized as follows: 1. The sex ratio of total offspring was 51.47% for male and significant at 5% level, and Landrace and Duroc breeds were 51.46% and 52.27% for male and significant at 5% level, respectively, but no significant difference between the breeds. 2. The sex ratio of offspring by years was 52.74% for male and significant at 5% level in 1979, but no significant difference for other years and between years. 3. The sex ratio of offspring by seasons were a little highly 51.65% and 51.25%, for male in spring and autumn, but no significant difference, respectively. 4. The sex ratio of offspring by parities were 52.65% and 55.81% for male in groups of the 3rd to 4th and the 5th to 6th parity, and significant difference at 5% and 1% level, respectively. 5. The sex ratio of offspring by groups of litter size was 52.65% for male in 1 to 6 heads group, and significant difference at 5% level, but no significant difference between groups of litter size.

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