• Steel and Composite Structures
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• v.39 no.3
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• pp.319-335
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• 2021

This study proposes a new and highly-accurate artificial intelligence model, namely ANN-IP, which combines an interior-point (IP) algorithm and artificial neural network (ANN), to improve the axial compression capacity prediction of elliptical concrete-filled steel tubular (CFST) columns. For this purpose, 145 tests of elliptical CFST columns extracted from the literature are used to develop the ANN-IP model. In this regard, axial compression capacity is considered as a function of the column length, the major axis diameter, the minor axis diameter, the thickness of the steel tube, the yield strength of the steel tube, and the compressive strength of concrete. The performance of the ANN-IP model is compared with the ANN-LM model, which uses the robust Levenberg-Marquardt (LM) algorithm to train the ANN model. The comparative results show that the ANN-IP model obtains more magnificent precision (R² = 0.983, RMSE = 59.963 kN, a20 - index = 0.979) than the ANN-LM model (R² = 0.938, RMSE = 116.634 kN, a20 - index = 0.890). Finally, a new Graphical User Interface (GUI) tool is developed to use the ANN-IP model for the practical design. In conclusion, this study reveals that the proposed ANN-IP model can properly predict the axial compression capacity of elliptical CFST columns and eliminate the need for conducting costly experiments to some extent.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.17 no.5
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• pp.37-44
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• 2018

In laser material processing for high thermal conductivity, the thermal effect of laser beam shape was examined through computer simulations. In this paper, a circular beam with a focal radius of $500{\mu}m$, an elliptical beam with a major axis of 4 mm and a minor axis of 1 mm, and a rotating beam with a focal radius of $500{\mu}m$ and an angular velocity of 5 rad/sec were compared. Simulation results showed that there was no clear difference in the maximum temperature between the circular focus and the elliptical shape, but the heating and cooling rates were different. The simulation result for a laser beam rotating in a circular pattern with a radius of 5 mm showed an asymmetric temperature rise due to the combination of linear and rotational motion. At points where the rotational and linear speeds combined, the temperature gradually rose and reached the maximum temperature; whereas at points where the rotational and linear speeds were attenuated, the temperature tended to gradually decrease after reaching the maximum temperature. Based on the results of this study, the authors expect to be able to optimize laser material processing by designing patterns of laser beams.

• Advances in Computational Design
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• v.4 no.3
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• pp.295-305
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• 2019

The sealing cement of total hip arthroplasty is the most widely used binder in orthopedic surgery for anchoring implants to their recipient bones. Nevertheless, this latter remains a fragile material with weak mechanical properties. Inside this material cracks initiate from cavities. These cracks propagate under the effect of fatigue and lead to the failure of this binder and consequently the loosening of the prosthesis. In this context, this work consists to predict the position of cracks initiation and their propagations path using the Extended Finite Element Method (XFEM). The results show that cracks can only be initiated from a sharp edges of an ellipsoidal cavity which the ratio of the minor axis over the major axis is equal to 0.1. A maximum crack length of 19 ?m found for a cavity situated in the proximal zone position under a static loading. All cracks propagate in same(almost) way regardless of the cavity(site of initiation) position and its inclination in the proximal zone.

• Journal of Microbiology and Biotechnology
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• v.33 no.9
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• pp.1111-1118
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• 2023

As a long-term condition that affects the airways and lungs, chronic obstructive pulmonary disease (COPD) is characterized by inflammation, emphysema, breathlessness, chronic cough, and sputum production. Currently, the bronchodilators and anti-inflammatory drugs prescribed for COPD are mostly off-target, warranting new disease management strategies. Accumulating research has revealed the gut-lung axis to be a bidirectional communication system. Cigarette smoke, a major exacerbating factor in COPD and lung inflammation, affects gut microbiota composition and diversity, causing gut microbiota dysbiosis, a condition that has recently been described in COPD patients and animal models. For this review, we focused on the gut-lung axis, which is influenced by gut microbial metabolites, bacterial translocation, and immune cell modulation. Further, we have summarized the findings of preclinical and clinical studies on the association between gut microbiota and COPD to provide a basis for using gut microbiota in therapeutic strategies against COPD. Our review also proposes that further research on probiotics, prebiotics, short-chain fatty acids, and fecal microbiota transplantation could assist therapeutic approaches targeting the gut microbiota to alleviate COPD.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.47 no.3
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• pp.18-30
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• 2024

Although concerns about overheating of the franchise industry's market structure continue to be raised, there are few studies that analyze the market structure of the franchise industry and suggest practical use. Most existing studies mainly analyze the market structure of other industries using industrial concentration(HHI) as an indicator of market competition intensity from the perspective of industrial organization theory. This study seeks to present a market structure analysis method that is different from existing methods. Considering practical application, this study presented a method to analyze the market structure that combines industry concentration(HHI) analysis and matrix analysis of the franchise industry. First, the industry concentration(HHI) and operating profit ratio(SMR) of 15 major industries in the franchise industry were analyzed in a time series manner (2014-2019). Second, using industrial concentration and operating profit ratio(SMR) as two variables on the x-axis and y-axis, a two-stage matrix analysis was used to understand the market structure characteristics of 15 industries at a glance. Third, a method of utilizing the matrix analysis results for practical decision-making was presented.

• The Journal of the Korea Contents Association
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• v.12 no.8
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• pp.380-387
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• 2012

A complex seismic survey, which is nondestructive inspection, is used often recently in estimating the location of reclaimed cultural assets. Such a method is the best way to estimate the location of cultural assets most effectively in a short time at a construction site. This study estimated the reclamation location of a cultural asset by using magnetic gradient survey, earth resistivity survey, and ground penetrating radar survey (GPR) in order to figure out the distribution territory in the area with possibility of creation of reclaimed cultural assets in the past. As a result, it was located at +15m on the X axis and +90m on the Y axis on the floor plane coordinate of the study target area. It was shown that the major axis is about 20m long in the north-northeast direction and the width is about 5m. The depth of development distribution of anomaly zone was estimated as about 1.5~3.0m. Geophysical survey is expected to be used as a efficient and accurate way to excavate the reclaimed cultural assets in future.

• Journal of the Korean Society of Hazard Mitigation
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• v.2 no.3 s.6
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• pp.119-125
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• 2002

The objective of this study is to evaluate elastic modulus of bridge-axis direction for optimum structure system in the cable-stayed bridge design. In numerical example of this study, a slight change in axis direction elastic modulus causes major modifications of the bridge characteristics when it is $1\times10^4$ tonf/m/bearing or less. Therefore, the elastic modulus was set at this lower limit of $1\times10^4$ tonf/m/bearing where the strength of the entire bridge system is still determined by girder strength and the entire system is insensitive to variations in elastic modulus. Besides, cable-stayed bridge with freely supported girders have slightly longer vibration periods in the horizontal direction for earthquake forces.

• Journal of architectural history
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• v.21 no.3
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• pp.29-44
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• 2012

If cultural Heritageis located in the downtown, conservation areas was developed or is being developed In most cases Therefore, in this case, the relative height of the building during construction than the regulatory limit is reasonable, is emerging need to be objectified. This study was utilizes GIS analysis techniques for 'View Corridor' and building height standards were determined. First, 'View Corridor' set and building height restrictions for the analysis of urban environmental factors were analyzed in. In particular, the topography and urban planning, and existing buildings, including the distribution of the physical urban environment, with detailed analysis on the major historical and cultural assets with a combination of a review of the impact factor for the formation of the urban landscape recognize the scope has been expanded. Second, the key selection criteria for View point largely focused on cultural Heritageand the surrounding communicative point of view and, consequently, connectivity, and symbolism, accessibility, analysis, factors such as Prospect, setting the standards by applying a detailed assessment of each item the main view point were derived. Third, the derived key View point on the terrain and landscape characteristics simulation analysis carried out by considering together the main axis, and this suggests a reasonable height for the proposed standards.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.23 no.10
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• pp.670-677
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• 2011

Direct numerical simulation are performed in order to investigate the effect of the circular cylinder shape on the forced convection around a circular cylinder at the Reynolds number of 300 and Prandtl number of 0.71. Three-dimensional characteristics of fluid flow and heat transfer around the smooth, wavy and torsional cylinders are investigated. A wavy cylinder has the sinusoidal variation in the cross sectional area along the spanwise direction with the wave length of ${\pi}/3$ and wavy amplitude of 0.1. A torsional cylinder has the twisted elliptic cross section with a torsional period of ${\pi}/2$ and an axis ratio of 1.35 corresponding to the major axis of 1.15 and the minor axis of 0.85. The value of time-and surface-averaged drag coefficient for the smooth cylinder is similar to that for the wavy cylinder, but larger than that for the torsional cylinder. The time and surface-averaged lift coefficient for the smooth cylinder is larger than that for the wavy and torsional cylinders. The time-averaged local heat transfer rate for the wavy and torsional cylinders shows different distribution along the circumferential direction, compared to that for the smooth cylinder because of the shape change in the spanwise direction for the cases of the wavy and torsional cylinders.

• The Korean Journal of Physiology and Pharmacology
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• v.27 no.1
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• pp.113-125
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• 2023

It has been reported that stressful events in early life influence behavior in adulthood and are associated with different psychiatric disorders, such as major depression, post-traumatic stress disorder, bipolar disorder, and anxiety disorder. Maternal separation (MS) is a representative animal model for reproducing childhood stress. It is used as an animal model for depression, and has well-known effects, such as increasing anxiety behavior and causing abnormalities in the hypothalamic-pituitary-adrenal (HPA) axis. This study investigated the effect of MS on anxiety or aggression-like behavior and the number of GABAergic neurons in the hippocampus. Mice were separated from their dams for four hours per day for 19 d from postnatal day two. Elevated plus maze (EPM) test, resident-intruder (RI) test, and counted glutamic acid decarboxylase 67 (GAD67) or parvalbumin (PV) positive cells in the hippocampus were executed using immunohistochemistry. The maternal segregation group exhibited increased anxiety and aggression in the EPM test and the RI test. GAD67-positive neurons were increased in the hippocampal regions we observed: dentate gyrus (DG), CA3, CA1, subiculum, presubiculum, and parasubiculum. PV-positive neurons were increased in the DG, CA3, presubiculum, and parasubiculum. Consistent with behavioral changes, corticosterone was increased in the MS group, suggesting that the behavioral changes induced by MS were expressed through the effect on the HPA axis. Altogether, MS alters anxiety and aggression levels, possibly through alteration of cytoarchitecture and output of the ventral hippocampus that induces the dysfunction of the HPA axis.