• BMB Reports
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• 제38권3호
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• pp.343-349
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• 2005

Gamma-glutamyltransferase (GGT, EC 2.3.2.2) which hydrolyzes glutathione (GSH), is required for the maintenance of normal intracellular GSH concentration. GGT is a membrane enzyme present in leukocytes and platelets. Its activity has also been observed in human neutrophils. In this study, GGT was purified from Triton X-100 solubilized neutrophils and its kinetic parameters were determined. For kinetic analyses of transpeptidation reaction, $\gamma$-glutamyl p-nitroanilide was used as the substrate and glycylglycine as the acceptor. Apparent $K_m$ values were determined as 1.8 mM for $\gamma$-glutamyl p-nitroanilide and 16.9 mM for glycylglycine. The optimum pH of GGT activity was 8.2 and the optimum temperature was $37^{\circ}C$. It had thermal stability with 58% relative activity at $56^{\circ}C$ for 30 min incubation. L-serine, in the presence of borate, was detected as the competetive inhibitor. Bromcresol green inhibited neutrophil GGT activity as a noncompetetive inhibitor. The neutrophils seem to contain only the isoenzyme that is present in platelets. We characterized the kinetic properties and compared the type of the isoenzyme of neutrophil GGT with platelet GGT via polyacrylamide gel electrophoresis (PAGE) under a standart set of conditions.

• 한국국방경영분석학회지
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• 제23권2호
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• pp.1-14
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• 1997

TPNSim++ is the object-oriented framework for the discrete event simulation of military systems, developed by authors. The simulation world view of TPNSim++ is on the basis of activity scanning. TPNSim++ is implemented as C++ class library under Windows 95/NT. It uses the extended timed Petri nets which are called TPNSim nets for simulation modeling tool. The aim of this study is to conduct a comparative study of TPNSim++ and SLAM II in the simulation of military maintenance systems for the validation and the applicability of TPNSim++. From this study, TPNSim++ and SLAMII have given the same results under the equivalent assumption. Thus we can get the validation of TPNSim++ and its applicability to the simulation of maintenance systems.

• 한국군사과학기술학회지
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• 제16권5호
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• pp.675-682
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• 2013

Reliability analysis and prediction of next failure time is critical to sustain weapon systems, concerning scheduled maintenance, spare parts replacement and maintenance interventions, etc. Since 1981, many methodology derived from various probabilistic and statistical theories has been suggested to do that activity. Nowadays, many A.I. tools have been used to support these predictions. Support Vector Regression(SVR) is a nonlinear regression technique extended from support vector machine. SVR can fit data flexibly and it has a wide variety of applications. This paper utilizes SVM and SVR with combining time series to predict the next failure time based on historical failure data. A numerical case using failure data from the military equipment is presented to demonstrate the performance of the proposed approach. Finally, the proposed approach is proved meaningful to predict next failure point and to estimate instantaneous failure rate and MTBF.

• Journal of Information Processing Systems
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• 제6권2호
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• pp.235-252
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• 2010

Regression testing is a very costly process performed primarily as a software maintenance activity. It is the process of retesting the modified parts of the software and ensuring that no new errors have been introduced into previously tested source code due to these modifications. A regression test selection technique selects an appropriate number of test cases from a test suite that might expose a fault in the modified program. In this paper, we propose both a regression test selection and prioritization technique. We implemented our regression test selection technique and demonstrated in two case studies that our technique is effective regarding selecting and prioritizing test cases. The results show that our technique may significantly reduce the number of test cases and thus the cost and resources for performing regression testing on modified software.

• 응용통계연구
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• 제23권3호
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• pp.573-584
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• 2010

This paper considers the differences in the software execution environments in the testing phase and the operational phase to determine the optimal release time and warranty period of software systems. We formulate equations for the total expected software cost until the end of the software life cycle based on the NHPP. In addition, we derive the optimal release time that minimizes the total expected software cost for an imperfect debugging software reliability model. Finally, we analyze the sensitivity of the optimal testing and maintenance design related to variation of the cost model parameters based on the fault data observed in the actual testing process, and discuss the quantitative properties of the proposed model.

• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 2006년도 춘계 학술발표회 논문집(II)
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• pp.261-264
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• 2006

Recently, the environment problems are risen to social problems. People have requested the convenience of a human activity and the enhancement of a human quality. The facility was, however, emphasized on the acquisition and treatment of water with the construction and maintenance of a irrigation and drainage structure. The concept of an environmental friendship has been introduced to change our society structure to an environment friendship at 21th century. But the concept lacks theoretical and systematic foundation. So, The maintenance technique, concrete products and construction methods will be made to be an environment friendship. The standards for environment friendship will be presented.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2001년도 하계학술대회 논문집 C
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• pp.1634-1636
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• 2001

We have developed the global assessment system for medium voltage power cable systems. Our purpose of diagnostic activity is the economic discrimination and maintenance of bad cables which is likely to cause cable system failure. We have atapted the Voltage Decay Method to construct the power cable assessment system for our diagnostic purpose. From the field application test results, we have concluded that our system is successful and convenient for the discrimination and maintenance of the damaged cables economically.

• Journal of Ginseng Research
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• 제24권2호
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• pp.83-88
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• 2000

6년생 고려인삼근(Panax ginseng C.A. Meyer) 중의 Sucrose synthase, UDP-glucose pyrophosphorylase 및 ADP-glucose pyrophosphorylase의 활성을 생육 시기별로 조사한 결과, Sucrose synthase 와 ADP-glucose pyrophosphorylase는 뿌리저장활성 지표로서 adaptive enzyme의 특성을 나타내는 반면, UDP-glucose pyrophosphorylase는 maintenance enzyme으로서 존재하였다. 평균기온이 24。C 이상일 때 전분합성이 저하되고 중심부의 산소소비량이 급격히 증가되었다.

• 품질경영학회지
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• 제30권4호
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• pp.154-163
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• 2002

This study tries to analyze how TPM works in domestic manufacturing industry by estimating two-stage model. First stage tests the effects of five TPM-factor variables (TFV : (1) Small group activity & Autonomous maintenance, (2) Education & Training, (3) Planned maintenance, (4) improving effectiveness of each piece of facility (5) Safety & Environment) to two TPM-performance variables. Second stage tests how two TPVs affect the industry's productivity level. By combining these two stages, this study uses a model to explain how TPM, represented by TFVs, works to improve productivity via TPVs. Multivariate and univariate regression and correlation analyses were peformed. It is shown that five TFVs works in two different ways to improve the industry's productivity level. In the second stage, overall equipment effectiveness has relatively more significant effects to the productivity level.

• 해양환경안전학회지
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• 제26권1호
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• pp.47-56
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• 2020

본 연구는 국내외 수중레저활동 관련 법률을 분석하여 국내 수중레저법에 대한 개선방안을 다음과 같이 제안한다. 첫째, 수중레저활동자는 '수중레저사업자로부터 계약을 통해 수중레저활동 서비스를 제공받으며 수중레저활동을 하는 사람'으로 개정되어야 한다. 둘째, 수중레저활동구역을 설치하는 주체는 '수중레저사업자 및 수중레저활동자 등'으로 확대되어야 한다. 셋째, 레저 테크니컬 다이빙은 나이트록스 또는 혼합 가스 등을 사용하므로 가스 종류가 명확히 기재된 스티커 또는 밴드를 부착하도록 규제가 추가되어야 한다. 넷째, 다이빙 필수 장비에 수면표시부표(SMB)를 추가하고 공기통에 대한 일상 관리 및 정비방법에 대한 규제조항이 추가되어야 한다. 다섯째, 수중레저활동자의 다이빙 보험가입을 적극 권유하도록 제도화 할 필요가 있다. 이외에도 수중레저활동자의 안전을 확보하기 위해 수중레저사업자의 응급절차와 다이빙 가이드라인을 구체적으로 명시할 필요가 있다.