• Journal of Korean Society of Industrial and Systems Engineering
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• v.42 no.4
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• pp.145-152
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• 2019

All machines deteriorate in performance over time. The phenomenon that causes such performance degradation is called deterioration. Due to the deterioration, the process mean of the machine shifts, process variance increases due to the expansion of separate interval, and the failure rate of the machine increases. The maintenance model is a matter of determining the timing of preventive maintenance that minimizes the total cost per wear between the relation to the increasing production cost and the decreasing maintenance cost. The essential requirement of this model is that the preventive maintenance cost is less than the failure maintenance cost. In the process mean shift model, determining the resetting timing due to increasing production costs is the same as the maintenance model. In determining the timing of machine adjustments, there are two differences between the models. First, the process mean shift model excludes failure from the model. This model is limited to the period during the operation of the machine. Second, in the maintenance model, the production cost is set as a general function of the operating time. But in the process mean shift model, the production cost is set as a probability functions associated with the product. In the production system, the maintenance cost of the equipment and the production cost due to the non-confirming items and the quality loss cost are always occurring simultaneously. So it is reasonable that the failure and process mean shift should be dealt with at the same time in determining the maintenance time. This study proposes a model that integrates both of them. In order to reflect the actual production system more accurately, this integrated model includes the items of process variance function and the loss function according to wear level.

• Tuberculosis and Respiratory Diseases
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• v.81 no.2
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• pp.148-155
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• 2018

Background: Although targeted therapy and immuno-oncology have shifted the treatment paradigm for lung cancer, platinum-based combination is still the standard of care for advanced non-small cell lung cancer (NSCLC). Pemetrexed continuation maintenance therapy has been approved and increasingly used for patients with nonsquamous NSCLC. However, the efficacy of this strategy has not been proven in patients without driving mutations. The objective of this study was to compare the clinical benefit of pemetrexed continuation maintenance to conventional platinum-based doublet in epidermal growth factor receptor (EGFR)-negative lung adenocarcinoma. Methods: A total of 114 patients with EGFR-negative lung adenocarcinoma who were treated with platinum doublet were retrospectively enrolled. We compared the survival rates between patients received pemetrexed maintenance after four-cycled pemetrexed/cisplatin and those received at least four-cycled platinum doublet without maintenance chemotherapy as a first-line treatment. Results: Forty-one patients received pemetrexed maintenance and 73 received conventional platinum doublet. Median progression-free survival (PFS), which was defined as the time from the day of response evaluation after four cycles of chemotherapy to disease progression or death, was significantly higher in the pemetrexed maintenance group compared to conventional group (5.8 months vs. 2.2 months, p<0.001). Median overall survival showed an increasing trend in the pemetrexed maintenance group (22.3 months vs. 16.1 months, p=0.098). Multivariate analyses showed that pemetrexed maintenance chemotherapy was associated with better PFS (hazard ratio, 0.73; 95% confidence interval, 0.15-0.87). Conclusion: Compared to conventional platinum-based chemotherapy, premetrexed continuation maintenance treatment is associated with better clinical outcome for the patients with EGFR wild-type lung adenocarcinoma.

• Journal of the Korean Society for Railway
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• v.11 no.1
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• pp.19-25
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• 2008

There are two main parts to improve the quality and the efficiency of railway service. One is to acquire the system with high RAMS performance and the other is to keep it up. Therefore we need to specify RAMS requirements in the system specifications and verify them. In addition, it is necessary to monitor RAMS and to make operation and maintenance policies based on RAMS. This article presents RAMS centered maintenance procedure of which target is to continuously achieve the inherent RAMS performance of the acquired system. The method to evaluate the effect on RAMS and the conceptual optimal model for determining maintenance interval are also proposed.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2008.05a
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• pp.257-262
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• 2008

This study presents a detailed analysis of aircraft engine maintenance cost based on the relationships between engine performance and geometric parameters. Some trend equations based on the engine performance and maintenance database were developed for the estimation of shop-visit interval, work-scope, man-hours, material cost and Life Limited Part cost. The results show that this approach can give a more reasonable and detailed estimation of engine maintenance cost than older empirical methods.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.9 no.2
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• pp.81-86
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• 2014

In this paper, a jointly optimal group replacement and spare provisioning policy is presented. Most maintenance policies assume that the spare inventory is always available, but in practice the maintenance schedule is affected by the availability of spare inventory. We present a maintenance-inventory model which jointly optimizes the group replacement interval and spare ordering quantity. Group replacement policy is used when a group of units are put in operation simultaneously. The operating fleet is replaced altogether at a predetermined number of units are failed. A sufficient level of spare inventory is carried to perform a number of group replacement. A cost rate expression which considers the group maintenance cost and inventory holding cost is derived and a heuristic method for searching the optimum value of decision variables is suggested. Numerical examples demonstrate the analytical results and the performance of the presented model.

• KIEAE Journal
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• v.3 no.3
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• pp.67-74
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• 2003

The repair and maintenance planning is the principal transaction to prevent from the degradation of apartment buildings to prolong their lives. Various building components as part of living area should be maintained properly and timely before critical defects are realized, then the building life might be extended until the limit of its usability. In other words, various building components such as utilities, finishes and structural members are needed to be repaired and replaced in different time interval after completion. To do this systematically, a maintenance management system for Long-Range Planning (LRP) needs developing. The LRP should be figured out based on the forecast of repairing and replacing cycle of building components according to work trades. And the precise forecast of repairing and replacing time of the components helps to enhance the usability of the developed system. The purpose of this paper is to suggest a system with which apartment building managers carry out the tasks of periodical check, diagnosis and replacement of building components based on the maintenance calendar. By using the system, they can easily forecast repairing and replacing time of the components with the consideration of life cycle of building materials and build the LRP.

• Physical Therapy Korea
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• v.3 no.1
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• pp.73-79
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• 1996

Photochemotherapy(UVA with 8-methoxypsoralen) was given to 30 patients with systemic psoriasis. The results of clearing and long-term(6-month) interval maintenance were reported. Clearing requirements were in general similar to these reported by Melski and Burger. The skin of the 14 patients (46.6%) recovered good skin condition by a once weekly maintenance dose. This result was better than that reported by other authors. 1. During initial treatment period, average number of treatment was 27.3 and average duration treatment was 24.8 weeks. 2. The factors to quit treatment were motion decrease, moving to the remote area, complications, etc. 3. Number of patient who received maintenance treatment was 14. 4. The complications reported from the patients were hyperpigmentation, nausea, headache, pruritis, vomiting, gastritis.

• 제어로봇시스템학회:학술대회논문집
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• 1996.10a
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• pp.271-274
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• 1996

In this paper we made a reliability analysis of power system pumps by using the dimensional reduction method which over comes the problem due to unavailability of enpugh data in the actual systems under many different operational environments. Hence a resonable method was proposed to determine the optimum maintenance interval of given pump in thermal power stations. This analysis was based on an actual data set of pumps for over ten years in thermal power stations belonged to Kyushu Electric Power Company, Japan.

• Journal of Korean Institute of Industrial Engineers
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• v.25 no.1
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• pp.47-55
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• 1999

This paper develops an efficient heuristic algorithm for scheduling workforce level that can accommodate all the requested maintenance jobs. Each job has its own release and due dates as well as man-day requirement, and must be scheduled in a non-interrupted time interval, namely, without preemption. Duration of each job is not fixed, but to be determined within given specific range. The objective is to minimize workforce level to complete all the requested maintenance jobs. We show that the problem can be seen as a variant of the two-dimensional bin-packing problem with some additional constraints. A non-linear mixed integer programming model for the problem is developed, and an efficient heuristic algorithm based on bin-packing algorithms is proposed. In order to evaluate goodness of the solution obtained from the proposed algorithm, a scheme for getting a good lower bound for the optimum solution is presented and analyzed. The computational experiment shows that the proposed algorithm performs quite satisfactorily.

• International Journal of Reliability and Applications
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• v.1 no.1
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• pp.15-26
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• 2000

This paper considers an aperiodic preventive maintenance (PM) model for repairable systems, in which the time intervals between two consecutive preventive maintenances are unequal. To propose such an aperiodic PM model, we assume that each PM reduces the current hazard rate by a certain amount which depends on the number of PMs performed previously. If the system fails between PMs, the minimal repair is performed and the hazard rate remains unchanged after the repair. We give the exact expressions for the hazard rate function for the aperiodic PM model. Based on the proposed aperiodic PM model, we suggest the maximum likelihood method to estimate the parameters characterizing the model and apply the method to the case of Weibull distribution. Numerical examples for estimating the parameters are presented for the purpose of illustration.